{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:03:47Z","timestamp":1793059427999,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.chest.2024.01.005","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T16:22:34Z","timestamp":1704817354000},"page":"1111-1119","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Effect of Atypical Sleep EEG Patterns on Weaning From Prolonged Mechanical Ventilation"],"prefix":"10.1016","volume":"165","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1033-1511","authenticated-orcid":false,"given":"Hameeda","family":"Shaikh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2931-3558","authenticated-orcid":false,"given":"Ramona","family":"Ionita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usman","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youngsook","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8762-3125","authenticated-orcid":false,"given":"Amal","family":"Jubran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin J.","family":"Tobin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Laghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chest.2024.01.005_bib1","series-title":"Principles and Practice of Mechanical Ventilation","first-page":"1293","article-title":"Sleep in the ventilator-supported patient","author":"Hanly","year":"2013"},{"issue":"3","key":"10.1016\/j.chest.2024.01.005_bib2","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1378\/chest.117.3.809","article-title":"Sleep in critically ill patients requiring mechanical ventilation","volume":"117","author":"Cooper","year":"2000","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.chest.2024.01.005_bib3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.sleep.2011.07.012","article-title":"A\u00a0new classification for sleep analysis in critically ill patients","volume":"13","author":"Drouot","year":"2012","journal-title":"Sleep Med"},{"issue":"4","key":"10.1016\/j.chest.2024.01.005_bib4","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02465-2017","article-title":"Impact of sleep alterations on weaning duration in mechanically ventilated patients: a prospective study","volume":"51","author":"Thille","year":"2018","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.chest.2024.01.005_bib5","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1097\/CCM.0b013e3181bc8243","article-title":"Poor sleep quality is associated with late noninvasive ventilation failure in patients with acute hypercapnic respiratory failure","volume":"38","author":"Campo","year":"2010","journal-title":"Crit Care Med"},{"issue":"5","key":"10.1016\/j.chest.2024.01.005_bib6","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1007\/s00134-010-1842-4","article-title":"Depressive disorders during weaning from prolonged mechanical ventilation","volume":"36","author":"Jubran","year":"2010","journal-title":"Intensive Care Med"},{"issue":"18","key":"10.1016\/j.chest.2024.01.005_bib7","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1001\/archinte.166.18.1993","article-title":"Brain dysfunction: another burden for the chronically critically ill","volume":"166","author":"Nelson","year":"2006","journal-title":"Arch Intern Med"},{"issue":"7","key":"10.1016\/j.chest.2024.01.005_bib8","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1001\/jama.2013.159","article-title":"Effect of pressure support vs\u00a0unassisted breathing through a tracheostomy collar on weaning duration in patients requiring prolonged mechanical ventilation: a randomized trial","volume":"309","author":"Jubran","year":"2013","journal-title":"JAMA"},{"issue":"12","key":"10.1016\/j.chest.2024.01.005_bib9","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1007\/s00134-001-1132-2","article-title":"The impact of delirium in the intensive care unit on hospital length of stay","volume":"27","author":"Ely","year":"2001","journal-title":"Intensive Care Med"},{"issue":"7","key":"10.1016\/j.chest.2024.01.005_bib10","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1097\/00003246-199907000-00022","article-title":"Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients","volume":"27","author":"Riker","year":"1999","journal-title":"Crit Care Med"},{"key":"10.1016\/j.chest.2024.01.005_bib11","series-title":"The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. Version 2.6","author":"Berry","year":"2020"},{"issue":"8","key":"10.1016\/j.chest.2024.01.005_bib12","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1097\/CCM.0b013e31828a3f75","article-title":"Atypical sleep in ventilated patients: empirical electroencephalography findings and the path toward revised ICU sleep scoring criteria","volume":"41","author":"Watson","year":"2013","journal-title":"Crit Care Med"},{"issue":"11","key":"10.1016\/j.chest.2024.01.005_bib13","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1093\/sleep\/31.11.1559","article-title":"Assessment of sleep in ventilator-supported critically ill patients","volume":"31","author":"Ambrogio","year":"2008","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.chest.2024.01.005_bib14","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.cmpb.2014.01.019","article-title":"Spectral and complexity analysis of scalp EEG characteristics for mild cognitive impairment and early Alzheimer's disease","volume":"114","author":"Mcbride","year":"2014","journal-title":"Comput Methods Programs Biomed"},{"issue":"5","key":"10.1016\/j.chest.2024.01.005_bib15","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1164\/rccm.2201090","article-title":"Contribution of the intensive care unit environment to sleep disruption in mechanically ventilated patients and healthy subjects","volume":"167","author":"Gabor","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"issue":"7","key":"10.1016\/j.chest.2024.01.005_bib16","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1097\/CCM.0b013e318287f569","article-title":"Comparison of sleep quality with mechanical versus spontaneous ventilation during weaning of critically ill tracheostomized patients","volume":"41","author":"Roche-Campo","year":"2013","journal-title":"Crit Care Med"},{"issue":"3","key":"10.1016\/j.chest.2024.01.005_bib17","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/sleep\/34.3.355","article-title":"Sleep disturbances in patients admitted to a step-down unit after ICU discharge: the role of mechanical ventilation","volume":"34","author":"Fanfulla","year":"2011","journal-title":"Sleep"},{"issue":"7","key":"10.1016\/j.chest.2024.01.005_bib18","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1007\/s00134-010-1870-0","article-title":"Physiological comparison of three spontaneous breathing trials in difficult-to-wean patients","volume":"36","author":"Cabello","year":"2010","journal-title":"Intensive Care Med"},{"issue":"1","key":"10.1016\/j.chest.2024.01.005_bib19","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/2110-5820-1-42","article-title":"Sleep quality in mechanically ventilated patients: comparison between NAVA and PSV modes","volume":"1","author":"Delisle","year":"2011","journal-title":"Ann Intensive Care"},{"issue":"6","key":"10.1016\/j.chest.2024.01.005_bib20","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/s00134-007-0618-y","article-title":"Subsyndromal delirium in the ICU: evidence for a disease spectrum","volume":"33","author":"Ouimet","year":"2007","journal-title":"Intensive Care Med"},{"issue":"6","key":"10.1016\/j.chest.2024.01.005_bib21","first-page":"447","article-title":"Subsyndromal delirium and institutionalization among patients with critical illness","volume":"26","author":"Brummel","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.chest.2024.01.005_bib22","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/1471-2202-9-86","article-title":"Serum anticholinergic activity and cerebral cholinergic dysfunction: an EEG study in frail elderly with and without delirium","volume":"9","author":"Thomas","year":"2008","journal-title":"BMC Neurosci"},{"issue":"2","key":"10.1016\/j.chest.2024.01.005_bib23","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1164\/ajrccm.163.2.9912128","article-title":"Abnormal sleep\/wake cycles and the effect of environmental noise on sleep disruption in the intensive care unit","volume":"163","author":"Freedman","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"10.1016\/j.chest.2024.01.005_bib24","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1164\/rccm.201811-2119OC","article-title":"Sleep and Pathological Wakefulness at Time of Liberation from Mechanical Ventilation (SLEEWE): a prospective multicenter physiological study","volume":"199","author":"Dres","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.chest.2024.01.005_bib25","first-page":"86","article-title":"EEG in delirium","volume":"5","author":"Jacobson","year":"2000","journal-title":"Semin Clin Neuropsychiatry"},{"issue":"1","key":"10.1016\/j.chest.2024.01.005_bib26","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.bja.2018.08.021","article-title":"Delirium detection using relative delta power based on 1-minute single-channel EEG: a multicentre study","volume":"122","author":"Numan","year":"2019","journal-title":"Br J Anaesth"},{"issue":"12","key":"10.1016\/j.chest.2024.01.005_bib27","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1007\/s00134-013-3105-7","article-title":"The accurate recognition of delirium in the ICU: the emperor\u2019s new clothes?","volume":"39","author":"Devlin","year":"2013","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.chest.2024.01.005_bib28","first-page":"432","article-title":"Alterations of cholinergic and monoamine neurotransmitters in cerebrospinal fluid in patients with postoperative delirium","volume":"12","author":"Yang","year":"2020","journal-title":"Chin J Behav Med Brain Sci"},{"issue":"12","key":"10.1016\/j.chest.2024.01.005_bib29","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.jagp.2013.09.005","article-title":"Neuropathogenesis of delirium: review of current etiologic theories and common pathways","volume":"21","author":"Maldonado","year":"2013","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.chest.2024.01.005_bib30","series-title":"Principles and Practice of Sleep Medicine","first-page":"62","article-title":"Neural control of sleep in mammals","author":"McGinty","year":"2017"},{"issue":"1","key":"10.1016\/j.chest.2024.01.005_bib31","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1378\/chest.08-1546","article-title":"Sleep in the ICU: potential mechanisms and clinical implications","volume":"136","author":"Hardin","year":"2009","journal-title":"Chest"},{"key":"10.1016\/j.chest.2024.01.005_bib32","series-title":"Principles and Practice of Sleep Medicine","first-page":"480","article-title":"Drugs that disturb sleep and wakefulness","author":"Schweitzer","year":"2017"},{"issue":"7","key":"10.1016\/j.chest.2024.01.005_bib33","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1097\/01.CCM.0000129485.08835.5A","article-title":"The symptom burden of chronic critical illness","volume":"32","author":"Nelson","year":"2004","journal-title":"Crit Care Med"},{"issue":"14","key":"10.1016\/j.chest.2024.01.005_bib34","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1001\/jama.291.14.1753","article-title":"Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit","volume":"291","author":"Ely","year":"2004","journal-title":"JAMA"},{"issue":"6","key":"10.1016\/j.chest.2024.01.005_bib35","first-page":"984","article-title":"Sleep deprivation and the control of ventilation","volume":"128","author":"White","year":"1983","journal-title":"Am Rev Respir Dis"},{"issue":"4","key":"10.1016\/j.chest.2024.01.005_bib36","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1164\/ajrccm\/140.4.907","article-title":"Sleep loss impairs inspiratory muscle endurance","volume":"140","author":"Chen","year":"1989","journal-title":"Am Rev Respir Dis"},{"issue":"7","key":"10.1016\/j.chest.2024.01.005_bib37","doi-asserted-by":"crossref","first-page":"435","DOI":"10.7326\/0003-4819-153-7-201010050-00006","article-title":"Insufficient sleep undermines dietary efforts to reduce adiposity","volume":"153","author":"Nedeltcheva","year":"2010","journal-title":"Ann Intern Med"},{"issue":"8","key":"10.1016\/j.chest.2024.01.005_bib38","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1164\/rccm.201904-0819OC","article-title":"Impact of sleep deprivation on respiratory motor output and endurance: a physiological study","volume":"201","author":"Rault","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.chest.2024.01.005_bib39","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/mus.22322","article-title":"Paradoxical sleep deprivation induces muscle atrophy","volume":"45","author":"Dattilo","year":"2012","journal-title":"Muscle Nerve"},{"issue":"1","key":"10.1016\/j.chest.2024.01.005_bib40","doi-asserted-by":"crossref","first-page":"E68","DOI":"10.1152\/ajpendo.00543.2004","article-title":"Chronic REM-sleep deprivation of rats elevates metabolic rate and increases uncoupling protein-1 gene expression in brown adipose tissue","volume":"289","author":"Koban","year":"2005","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"4","key":"10.1016\/j.chest.2024.01.005_bib41","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1055\/s-0034-1381953","article-title":"Weaning from mechanical ventilation","volume":"35","author":"Shaikh","year":"2014","journal-title":"Semin Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.chest.2024.01.005_bib42","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ccm.2019.02.012","article-title":"Why physiology is critical to the practice of medicine: a 40-year personal perspective","volume":"40","author":"Tobin","year":"2019","journal-title":"Clin Chest Med"},{"key":"10.1016\/j.chest.2024.01.005_bib43","series-title":"Modern Epidemiology","first-page":"82","author":"Rothman","year":"1986"},{"issue":"6156","key":"10.1016\/j.chest.2024.01.005_bib44","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1126\/science.1241224","article-title":"Sleep drives\u00a0metabolite clearance from the adult brain","volume":"342","author":"Xie","year":"2013","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.chest.2024.01.005_bib45","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1001\/jamaneurol.2014.1173","article-title":"Effect of 1 night of total sleep deprivation on cerebrospinal fluid \u03b2-amyloid 42 in healthy middle-aged men: a randomized clinical trial","volume":"71","author":"Ooms","year":"2014","journal-title":"JAMA Neurol"},{"issue":"9188","key":"10.1016\/j.chest.2024.01.005_bib46","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/S0140-6736(99)01376-8","article-title":"Impact of sleep debt on metabolic and endocrine function","volume":"354","author":"Spiegel","year":"1999","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.chest.2024.01.005_bib47","doi-asserted-by":"crossref","first-page":"R905","DOI":"10.1152\/ajpregu.2000.278.4.R905","article-title":"Systemic bacterial invasion induced by sleep deprivation","volume":"278","author":"Everson","year":"2000","journal-title":"Am J Physiol Regul Integre Comp Physiol"},{"issue":"3","key":"10.1016\/j.chest.2024.01.005_bib48","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/psyg.12314","article-title":"Suvorexant is associated with a low incidence of delirium in critically ill patients: a retrospective cohort study","volume":"18","author":"Masuyama","year":"2018","journal-title":"Psychogeriatrics"},{"issue":"7","key":"10.1016\/j.chest.2024.01.005_bib49","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1097\/CCM.0000000000003132","article-title":"Effect of administration of ramelteon, a melatonin receptor agonist, on the duration of stay in the ICU: a single-center randomized placebo-controlled trial","volume":"46","author":"Nishikimi","year":"2018","journal-title":"Crit Care Med"},{"issue":"3","key":"10.1016\/j.chest.2024.01.005_bib50","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1097\/CCM.0b013e3182746442","article-title":"The effect of a quality improvement intervention on perceived sleep quality and cognition in a medical ICU","volume":"41","author":"Kamdar","year":"2013","journal-title":"Crit Care Med"}],"container-title":["CHEST"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369224000114?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369224000114?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T12:59:46Z","timestamp":1717592386000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369224000114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":50,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S0012369224000114"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2024.01.005","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of Atypical Sleep EEG Patterns on Weaning From Prolonged Mechanical Ventilation","name":"articletitle","label":"Article Title"},{"value":"CHEST","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2024.01.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. under license from the American College of Chest Physicians.","name":"copyright","label":"Copyright"}]}}