{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T02:36:22Z","timestamp":1772678182924,"version":"3.50.1"},"reference-count":10,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.chest.2024.07.141","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T09:11:15Z","timestamp":1733735475000},"page":"1264-1265","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Dexmedetomidine for Decatecholaminization in Septic Shock"],"prefix":"10.1016","volume":"166","author":[{"given":"Daisuke","family":"Hasegawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8806-2852","authenticated-orcid":false,"given":"Ryota","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.chest.2024.07.141_bib1","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/00000542-200008000-00016","article-title":"The effects of increasing plasma concentrations of dexmedetomidine in humans","volume":"93","author":"Ebert","year":"2000","journal-title":"Anesthesiology"},{"issue":"6","key":"10.1016\/j.chest.2024.07.141_bib2","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1016\/j.chest.2024.06.3794","article-title":"Dexmedetomidine for reducing mortality in patients with septic shock: a randomized controlled trial (DecatSepsis)","volume":"166","author":"Al-regal","year":"2024","journal-title":"Chest"},{"issue":"15","key":"10.1016\/j.chest.2024.07.141_bib3","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1056\/NEJMoa2024922","article-title":"Dexmedetomidine or propofol for sedation in mechanically ventilated adults with sepsis","volume":"384","author":"Hughes","year":"2021","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.chest.2024.07.141_bib4","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1016\/j.chest.2021.01.009","article-title":"Effect of ultrashort-acting \u03b2-blockers on mortality in patients with sepsis with persistent tachycardia despite initial resuscitation: a systematic review and meta-analysis of randomized controlled trials","volume":"159","author":"Hasegawa","year":"2021","journal-title":"Chest"},{"issue":"17","key":"10.1016\/j.chest.2024.07.141_bib5","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1001\/jama.2023.20134","article-title":"Landiolol and organ failure in patients with septic shock: the STRESS-L randomized clinical trial","volume":"330","author":"Whitehouse","year":"2023","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.chest.2024.07.141_bib6","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s00134-019-05596-z","article-title":"Cardiovascular clusters in septic shock combining clinical and echocardiographic parameters: a post hoc analysis","volume":"45","author":"Geri","year":"2019","journal-title":"Intensive Care Med"},{"issue":"1","key":"10.1016\/j.chest.2024.07.141_bib7","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s13613-022-01052-2","article-title":"Use of dexmedetomidine in patients with sepsis: a systematic review and meta-analysis of randomized-controlled trials","volume":"12","author":"Zhang","year":"2022","journal-title":"Ann Intensive Care"},{"issue":"6","key":"10.1016\/j.chest.2024.07.141_bib8","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.bja.2020.05.058","article-title":"Systolic-dicrotic notch pressure difference can identify tachycardic patients with septic shock at risk of cardiovascular decompensation following pharmacological heart rate reduction","volume":"125","author":"Morelli","year":"2020","journal-title":"Br J Anaesth"},{"issue":"1","key":"10.1016\/j.chest.2024.07.141_bib9","doi-asserted-by":"crossref","first-page":"6234","DOI":"10.1038\/s41598-024-55667-5","article-title":"Identification of a hyperinflammatory sepsis phenotype using protein biomarker and clinical data in the ProCESS randomized trial","volume":"14","author":"DeMerle","year":"2024","journal-title":"Sci Rep"},{"issue":"18","key":"10.1016\/j.chest.2024.07.141_bib10","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1056\/NEJMoa1401602","article-title":"A\u00a0randomized trial of protocol-based care for early septic shock","volume":"370","author":"Yealy","year":"2014","journal-title":"N\u00a0Engl J Med"}],"container-title":["CHEST"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369224048426?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369224048426?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T09:38:52Z","timestamp":1733737132000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369224048426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0012369224048426"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2024.07.141","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dexmedetomidine for Decatecholaminization in Septic Shock","name":"articletitle","label":"Article Title"},{"value":"CHEST","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2024.07.141","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2024.06.3794","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American College of Chest Physicians. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}