{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T21:24:32Z","timestamp":1787261072913,"version":"build-2736575974"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T00:00:00Z","timestamp":1783814400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.chest.2025.10.007","type":"journal-article","created":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T14:19:13Z","timestamp":1760278753000},"page":"262-272","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long-Term Major Respiratory Mortality Among 5-Year Survivors of Adolescent and Young Adult Cancer"],"prefix":"10.1016","volume":"170","author":[{"given":"Po","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenping","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunwei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxing","family":"Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9013-658X","authenticated-orcid":false,"given":"Lai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.chest.2025.10.007_bib1","first-page":"443","article-title":"Cancer statistics for adolescents and young adults, 2020","volume":"70","author":"Miller","year":"2020","journal-title":"CA Cancer Clin J"},{"issue":"13","key":"10.1016\/j.chest.2025.10.007_bib2","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1161\/CIRCULATIONAHA.116.025778","article-title":"Risk of cerebrovascular events in 178 962 five-year survivors of cancer diagnosed at 15 to 39 years of age: the TYACSS (Teenage and Young Adult Cancer Survivor Study)","volume":"135","author":"Bright","year":"2017","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.chest.2025.10.007_bib3","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1002\/cncr.32063","article-title":"Noncancer mortality among adolescents and young adults with cancer","volume":"125","author":"Anderson","year":"2019","journal-title":"Cancer"},{"issue":"17","key":"10.1016\/j.chest.2025.10.007_bib4","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1161\/CIR.0b013e3182a88099","article-title":"Long-term cardiovascular toxicity in children, adolescents, and young adults who receive cancer therapy: pathophysiology, course, monitoring, management, prevention, and research directions: a scientific statement from the American Heart Association","volume":"128","author":"Lipshultz","year":"2013","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.chest.2025.10.007_bib5","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/eurheartj\/ehaa779","article-title":"Long-term cardiovascular disease mortality among 160 834 5-year survivors of adolescent and young adult cancer: an American population-based cohort study","volume":"42","author":"Wang","year":"2021","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1016\/j.chest.2025.10.007_bib6","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1053\/j.seminoncol.2013.09.009","article-title":"Renal and pulmonary late effects of cancer therapy","volume":"40","author":"Skinner","year":"2013","journal-title":"Semin Oncol"},{"issue":"11","key":"10.1016\/j.chest.2025.10.007_bib7","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1007\/s00432-015-1974-6","article-title":"Radiation-induced fibrosis: mechanisms and implications for therapy","volume":"141","author":"Straub","year":"2015","journal-title":"J Cancer Res Clin Oncol"},{"issue":"6","key":"10.1016\/j.chest.2025.10.007_bib8","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1080\/0284186X.2017.1406137","article-title":"Obstructive and restrictive pulmonary dysfunction in long-term lymphoma survivors after high-dose therapy with autologous stem cell transplantation","volume":"57","author":"Stenehjem","year":"2018","journal-title":"Acta Oncol"},{"issue":"11","key":"10.1016\/j.chest.2025.10.007_bib9","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1002\/cncr.10978","article-title":"Pulmonary complications in survivors of childhood and adolescent cancer. A report from the Childhood Cancer Survivor Study","volume":"95","author":"Mertens","year":"2002","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.chest.2025.10.007_bib10","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.26749","article-title":"Long-term pulmonary disease among Swiss childhood cancer survivors","volume":"65","author":"Kasteler","year":"2018","journal-title":"Pediatr Blood Cancer"},{"issue":"4","key":"10.1016\/j.chest.2025.10.007_bib11","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1378\/chest.10-2133","article-title":"Pulmonary outcomes in survivors of childhood cancer: a systematic review","volume":"140","author":"Huang","year":"2011","journal-title":"Chest"},{"issue":"19","key":"10.1016\/j.chest.2025.10.007_bib12","doi-asserted-by":"crossref","first-page":"3924","DOI":"10.1002\/cncr.31650","article-title":"Respiratory emergency department use from diagnosis through survivorship in children, adolescents, and young adults with cancer","volume":"124","author":"Ramsay","year":"2018","journal-title":"Cancer"},{"issue":"10","key":"10.1016\/j.chest.2025.10.007_bib13","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1136\/thoraxjnl-2017-210683","article-title":"Respiratory mortality of childhood, adolescent and young adult cancer survivors","volume":"73","author":"Fidler","year":"2018","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.chest.2025.10.007_bib14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/ijc.32066","article-title":"Respiratory morbidity in young people surviving cancer: population-based study of hospital admissions, treatment-related risk factors and subsequent mortality","volume":"145","author":"Smith","year":"2019","journal-title":"Int J Cancer"},{"issue":"16","key":"10.1016\/j.chest.2025.10.007_bib15","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1002\/cncr.25129","article-title":"A survey of image-guided radiation therapy use in the United States","volume":"116","author":"Simpson","year":"2010","journal-title":"Cancer"},{"key":"10.1016\/j.chest.2025.10.007_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugalcdep.2019.107635","article-title":"Social norms towards smoking and vaping and associations with product use among youth in England, Canada, and the US","volume":"205","author":"East","year":"2019","journal-title":"Drug Alcohol Depend"},{"issue":"44","key":"10.1016\/j.chest.2025.10.007_bib17","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.15585\/mmwr.mm6544a2","article-title":"Current cigarette smoking among adults\u2014United States, 2005-2015","volume":"65","author":"Jamal","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"1","key":"10.1016\/j.chest.2025.10.007_bib18","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1186\/s12916-024-03635-1","article-title":"Trends in non-daily cigarette smoking in England, 2006-2024","volume":"22","author":"Jackson","year":"2024","journal-title":"BMC Med"},{"issue":"18","key":"10.1016\/j.chest.2025.10.007_bib19","doi-asserted-by":"crossref","first-page":"475","DOI":"10.15585\/mmwr.mm7218a1","article-title":"Tobacco product use among adults\u2014United States, 2021","volume":"72","author":"Cornelius","year":"2023","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"7","key":"10.1016\/j.chest.2025.10.007_bib20","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1002\/cncr.21773","article-title":"Classification schemes for tumors diagnosed in adolescents and young adults","volume":"106","author":"Barr","year":"2006","journal-title":"Cancer"},{"issue":"7","key":"10.1016\/j.chest.2025.10.007_bib21","doi-asserted-by":"crossref","first-page":"742","DOI":"10.4103\/indianjpsychiatry.indianjpsychiatry_578_22","article-title":"Brief intervention to enhance cessation of smokeless tobacco use in newly diagnosed patients with head and neck cancers: a randomized controlled trial in patient-relative dyads","volume":"65","author":"Tikka","year":"2023","journal-title":"Indian J Psychiatry"},{"key":"10.1016\/j.chest.2025.10.007_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2024.102487","article-title":"Recommendations for surveillance of pulmonary dysfunction among childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group","volume":"69","author":"Otth","year":"2024","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.chest.2025.10.007_bib23","article-title":"Breast cancer radiation therapy: a bibliometric analysis of the scientific literature","volume":"39","author":"Franco","year":"2023","journal-title":"Clin Transl Radiat Oncol"},{"issue":"32","key":"10.1016\/j.chest.2025.10.007_bib24","first-page":"35","article-title":"Time and generational trends in smoking among men and women in Great Britain, 1972-2004\/05","author":"Davy","year":"2006","journal-title":"Health Stat"},{"issue":"12","key":"10.1016\/j.chest.2025.10.007_bib25","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1093\/ntr\/ntz007","article-title":"Likelihood of smoking among cancer survivors: an updated health information national trends survey analysis","volume":"21","author":"Swoboda","year":"2019","journal-title":"Nicotine Tob Res"},{"key":"10.1016\/j.chest.2025.10.007_bib26","unstructured":"National Cancer Institute, Cancer Trends Progress Report. National Cancer Institute website. Accessed May 20, 2024. https:\/\/progressreport.cancer.gov."},{"issue":"15","key":"10.1016\/j.chest.2025.10.007_bib27","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1093\/jnci\/djn210","article-title":"Extent of smoking and age at initiation of smoking among adult survivors of childhood cancer in Britain","volume":"100","author":"Frobisher","year":"2008","journal-title":"J Natl Cancer Inst"},{"issue":"14","key":"10.1016\/j.chest.2025.10.007_bib28","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1200\/JCO.2014.59.8318","article-title":"Long-term pulmonary function in survivors of childhood cancer","volume":"33","author":"Armenian","year":"2015","journal-title":"J Clin Oncol"},{"issue":"12","key":"10.1016\/j.chest.2025.10.007_bib29","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1136\/thoraxjnl-2011-200618","article-title":"Pulmonary function impairment measured by pulmonary function tests in long-term survivors of childhood cancer","volume":"66","author":"Mulder","year":"2011","journal-title":"Thorax"},{"issue":"4","key":"10.1016\/j.chest.2025.10.007_bib30","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1002\/cncr.32617","article-title":"Adverse respiratory outcomes among head and neck cancer survivors in the Utah Cancer Survivors Study","volume":"126","author":"Kawakita","year":"2020","journal-title":"Cancer"},{"issue":"4","key":"10.1016\/j.chest.2025.10.007_bib31","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1164\/rccm.201204-0596PP","article-title":"Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary","volume":"187","author":"Vestbo","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.chest.2025.10.007_bib32","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/pon.3388","article-title":"Tobacco use among long-term survivors of head and neck cancer treated with radiation therapy","volume":"23","author":"Chen","year":"2014","journal-title":"Psycho-oncology"},{"issue":"9","key":"10.1016\/j.chest.2025.10.007_bib33","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1002\/pon.3682","article-title":"Post-operative smoking status in lung and head and neck cancer patients: association with depressive symptomatology, pain, and fatigue","volume":"24","author":"Bloom","year":"2015","journal-title":"Psycho-oncology"},{"issue":"9","key":"10.1016\/j.chest.2025.10.007_bib34","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1001\/jamaoto.2013.4072","article-title":"Depression among long-term survivors of head and neck cancer treated with radiation therapy","volume":"139","author":"Chen","year":"2013","journal-title":"JAMA Otolaryngolo Head Neck Surg"},{"issue":"6","key":"10.1016\/j.chest.2025.10.007_bib35","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1002\/cncr.21284","article-title":"Intensity-modulated radiation therapy use in the U.S., 2004","volume":"104","author":"Mell","year":"2005","journal-title":"Cancer"}],"container-title":["CHEST"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369225055114?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369225055114?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T20:32:47Z","timestamp":1787257967000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369225055114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0012369225055114"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2025.10.007","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-Term Major Respiratory Mortality Among 5-Year Survivors of Adolescent and Young Adult Cancer","name":"articletitle","label":"Article Title"},{"value":"CHEST","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2025.10.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc under license from the American College of Chest Physicians.","name":"copyright","label":"Copyright"}]}}