{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T12:16:28Z","timestamp":1773058588108,"version":"3.50.1"},"reference-count":20,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.chest.2025.11.039","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:12:05Z","timestamp":1767831125000},"page":"790-802","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Influence of Heart Failure and Ventilatory Support Mode on Hospital Morbidity and Mortality in Patients With or at Risk of Obesity Hypoventilation Syndrome"],"prefix":"10.1016","volume":"169","author":[{"given":"Roop","family":"Kaw","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shashank","family":"Shekhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reena","family":"Mehra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loutfi","family":"Aboussouan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babak","family":"Mokhlesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.chest.2025.11.039_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.amjmed.2003.08.022","article-title":"Obesity associated hypoventilation in hospitalized patients: prevalence, effects and outcome","volume":"116","author":"Nowbar","year":"2004","journal-title":"Am J Med"},{"key":"10.1016\/j.chest.2025.11.039_bib2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/1471-2466-13-68","article-title":"Perseverant, non-indicated treatment of obese patients for obstructive lung disease","volume":"13","author":"Fortis","year":"2013","journal-title":"BMC Pulm Med"},{"issue":"5","key":"10.1016\/j.chest.2025.11.039_bib3","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1136\/thx.2006.075945\/10.1136\/thx.2006.074245","article-title":"Previously undiagnosed obesity hypoventilation syndrome","volume":"62","author":"Quint","year":"2007","journal-title":"Thorax"},{"issue":"3","key":"10.1016\/j.chest.2025.11.039_bib4","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1378\/chest.11-0948","article-title":"Risk of misdiagnosis, health-related quality of life, and BMI in patients who are overweight with doctor-diagnosed asthma","volume":"141","author":"Scott","year":"2012","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.chest.2025.11.039_bib5","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1164\/rccm.201905-1071ST","article-title":"Evaluation and management of obesity hypoventilation syndrome, 2019, An official American Thoracic Society Clinical Practice Guideline","volume":"200","author":"Mokhlesi","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.chest.2025.11.039_bib6","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1177\/0885066612444261","article-title":"Characteristics of patients with the \u201cmalignant obesity hypoventilation syndrome\u201d admitted to an ICU","volume":"28","author":"Marik","year":"2013","journal-title":"J Intensive Care Med"},{"issue":"12","key":"10.1016\/j.chest.2025.11.039_bib7","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.4187\/respcare.06901","article-title":"Acute respiratory failure in obesity-hypoventilation syndrome managed in the ICU","volume":"64","author":"Chebib","year":"2019","journal-title":"Respir Care"},{"key":"10.1016\/j.chest.2025.11.039_bib9","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.chest.2025.11.039_bib10","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1016\/j.jcin.2020.10.007","article-title":"Reply: Tavr with or without embolic cerebral protection","volume":"13","author":"Megaly","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"issue":"2","key":"10.1016\/j.chest.2025.11.039_bib11","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1378\/chest.128.2.587","article-title":"Short-term and long-term effects of nasal intermittent positive pressure ventilation in patients with obesity-hypoventilation syndrome","volume":"128","author":"Perez de Llano","year":"2005","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.chest.2025.11.039_bib12","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1378\/chest.10-2531","article-title":"Noninvasive ventilation in mild obesity hypoventilation syndrome: a randomized controlled trial","volume":"141","author":"Borel","year":"2012","journal-title":"Chest"},{"key":"10.1016\/j.chest.2025.11.039_bib13","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1164\/rccm.201206-1101OC","article-title":"Non invasive ventilation in acute hypercapnic respiratory failure caused by obesity hypoventilation syndrome and chronic obstructive pulmonary disease","volume":"186","author":"Carillo","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.chest.2025.11.039_bib14","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1161\/CIRCULATIONAHA.116.026807","article-title":"Evidence supporting the existence of a distinct obese phenotype of heart failure with preserved ejection fraction","volume":"136","author":"Obokata","year":"2017","journal-title":"Circulation"},{"issue":"20","key":"10.1016\/j.chest.2025.11.039_bib15","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1093\/eurheartj\/ehab911","article-title":"Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality","volume":"43","author":"Verbrugge","year":"2022","journal-title":"Our Heart J"},{"issue":"2","key":"10.1016\/j.chest.2025.11.039_bib16","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/ejhf.2377","article-title":"Uncoupling between intravascular and distending pressures leads to underestimation of circulatory congestion in obesity","volume":"24","author":"Obokata","year":"2022","journal-title":"Eur J Heart Fail"},{"issue":"12","key":"10.1016\/j.chest.2025.11.039_bib17","first-page":"1089","article-title":"Central hemodynamic abnormality and outcome in patients with unexplained dyspnea","volume":"387","author":"Omote","year":"2022","journal-title":"Eur J Heart Fail"},{"issue":"1","key":"10.1016\/j.chest.2025.11.039_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052006","article-title":"Comorbidities and mortality in hypercapnic obese under domiciliary non-invasive ventilation","volume":"8","author":"Borel","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.chest.2025.11.039_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0117808","article-title":"Obesity-hypoventilation syndrome: increased risk of death over sleep apnea syndrome","volume":"10","author":"Castro-Anon","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.chest.2025.11.039_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2024.107813","article-title":"Obesity hypoventilation syndrome is associated with worse in-hospital outcomes in patients with acute myocardial infarction: a nationwide study","volume":"234","author":"Mohamoud","year":"2024","journal-title":"Respir Med"},{"issue":"12","key":"10.1016\/j.chest.2025.11.039_bib21","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1513\/AnnalsATS.202305-469OC","article-title":"Sleep-disordered breathing and inpatient outcomes in nonsurgical patients: analysis of the nationwide inpatient cohort","volume":"20","author":"May","year":"2023","journal-title":"Ann Am Thorac Soc"}],"container-title":["CHEST"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369225058210?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369225058210?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:32:32Z","timestamp":1773048752000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369225058210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S0012369225058210"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2025.11.039","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Influence of Heart Failure and Ventilatory Support Mode on Hospital Morbidity and Mortality in Patients With or at Risk of Obesity Hypoventilation Syndrome","name":"articletitle","label":"Article Title"},{"value":"CHEST","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2025.11.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American College of Chest Physicians. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}