{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:07:28Z","timestamp":1791234448288,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":1262,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Host & Microbe"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.chom.2010.01.004","type":"journal-article","created":{"date-parts":[[2010,2,12]],"date-time":"2010-02-12T04:47:04Z","timestamp":1265950024000},"page":"128-139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":316,"title":["Enhanced Infection of Liver Sinusoidal Endothelial Cells in a Mouse Model of Antibody-Induced Severe Dengue Disease"],"prefix":"10.1016","volume":"7","author":[{"given":"Rapha\u00ebl M.","family":"Zellweger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler R.","family":"Prestwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujan","family":"Shresta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chom.2010.01.004_bib1","doi-asserted-by":"crossref","first-page":"416","DOI":"10.4269\/ajtmh.2009.80.416","article-title":"Tropism of dengue virus in mice and humans defined by viral nonstructural protein 3-specific immunostaining","volume":"80","author":"Balsitis","year":"2009","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.chom.2010.01.004_bib2","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1084\/jem.193.6.671","article-title":"A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection","volume":"193","author":"Bashirova","year":"2001","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.chom.2010.01.004_bib3","doi-asserted-by":"crossref","first-page":"13325","DOI":"10.1128\/JVI.01568-07","article-title":"Primary human splenic macrophages, but not T or B cells, are the principal target cells for dengue virus infection in\u00a0vitro","volume":"81","author":"Blackley","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.chom.2010.01.004_bib4","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.1128\/JVI.02484-07","article-title":"Role of dendritic cells in antibody-dependent enhancement of dengue virus infection","volume":"82","author":"Boonnak","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.chom.2010.01.004_bib5","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1038\/nm1492","article-title":"Interleukin-10 determines viral clearance or persistence in\u00a0vivo","volume":"12","author":"Brooks","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.chom.2010.01.004_bib6","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1038\/nri891","article-title":"Antibodies, viruses and vaccines","volume":"2","author":"Burton","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.chom.2010.01.004_bib7","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1574-695X.2000.tb01474.x","article-title":"Cytokine cascade in dengue hemorrhagic fever: implications for pathogenesis","volume":"28","author":"Chaturvedi","year":"2000","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.chom.2010.01.004_bib8","doi-asserted-by":"crossref","first-page":"441","DOI":"10.4269\/ajtmh.2005.73.441","article-title":"Endoscopic findings and management of dengue patients with upper gastrointestinal bleeding","volume":"73","author":"Chiu","year":"2005","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.chom.2010.01.004_bib9","doi-asserted-by":"crossref","first-page":"7814","DOI":"10.1128\/JVI.74.17.7814-7823.2000","article-title":"Infection of human cells by dengue virus is modulated by different cell types and viral strains","volume":"74","author":"Diamond","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.chom.2010.01.004_bib10","first-page":"G391","article-title":"The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity","volume":"294","author":"Elvevold","year":"2008","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.chom.2010.01.004_bib11","doi-asserted-by":"crossref","first-page":"9422","DOI":"10.1073\/pnas.0703498104","article-title":"Monoclonal antibody-mediated enhancement of dengue virus infection in\u00a0vitro and in\u00a0vivo and strategies for prevention","volume":"104","author":"Goncalvez","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2010.01.004_bib12","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1086\/314680","article-title":"Early immune activation in acute dengue illness is related to development of plasma leakage and disease severity","volume":"179","author":"Green","year":"1999","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.chom.2010.01.004_bib13","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1093\/infdis\/140.4.527","article-title":"In vivo enhancement of dengue virus infection in rhesus monkeys by passively transferred antibody","volume":"140","author":"Halstead","year":"1979","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.chom.2010.01.004_bib14","first-page":"301","article-title":"Immune enhancement of viral infection","volume":"31","author":"Halstead","year":"1982","journal-title":"Prog. Allergy"},{"key":"10.1016\/j.chom.2010.01.004_bib15","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0065-3527(03)60011-4","article-title":"Neutralization and antibody-dependent enhancement of dengue viruses","volume":"60","author":"Halstead","year":"2003","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.chom.2010.01.004_bib16","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1016\/S0140-6736(07)61687-0","article-title":"Dengue","volume":"370","author":"Halstead","year":"2007","journal-title":"Lancet"},{"issue":"Suppl","key":"10.1016\/j.chom.2010.01.004_bib17","first-page":"96","article-title":"Hemorrhagic fever in Thailand; recent knowledge regarding etiology","volume":"20","author":"Halstead","year":"1967","journal-title":"Jpn. J.\u00a0Med. Sci. Biol."},{"key":"10.1016\/j.chom.2010.01.004_bib18","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1084\/jem.146.1.218","article-title":"Dengue viruses and mononuclear phagocytes. II. Identity of blood and tissue leukocytes supporting in\u00a0vitro infection","volume":"146","author":"Halstead","year":"1977","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.chom.2010.01.004_bib19","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1086\/383043","article-title":"Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in\u00a0situ hybridization","volume":"189","author":"Jessie","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.chom.2010.01.004_bib20","doi-asserted-by":"crossref","first-page":"5414","DOI":"10.1128\/JVI.79.9.5414-5420.2005","article-title":"Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression","volume":"79","author":"Jones","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.chom.2010.01.004_bib21","doi-asserted-by":"crossref","first-page":"230","DOI":"10.4049\/jimmunol.173.1.230","article-title":"Liver sinusoidal endothelial cells are insufficient to activate T\u00a0cells","volume":"173","author":"Katz","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.chom.2010.01.004_bib22","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jcv.2007.04.006","article-title":"The differences of clinical manifestations and laboratory findings in children and adults with dengue virus infection","volume":"39","author":"Kittigul","year":"2007","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.chom.2010.01.004_bib23","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/jmv.21051","article-title":"Monocytes, but not T or B cells, are the principal target cells for dengue virus (DV) infection among human peripheral blood mononuclear cells","volume":"80","author":"Kou","year":"2008","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.chom.2010.01.004_bib24","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1128\/JCM.43.7.3267-3272.2005","article-title":"Flow cytometry-based assay for titrating dengue virus","volume":"43","author":"Lambeth","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.chom.2010.01.004_bib25","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.chom.2007.09.015","article-title":"Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specific manner","volume":"2","author":"Mehlhop","year":"2007","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.chom.2010.01.004_bib26","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1371\/journal.ppat.0040017","article-title":"The mannose receptor mediates dengue virus infection of macrophages","volume":"4","author":"Miller","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.chom.2010.01.004_bib27","doi-asserted-by":"crossref","first-page":"14333","DOI":"10.1073\/pnas.2335168100","article-title":"Inhibition of interferon signaling by dengue virus","volume":"100","author":"Munoz-Jordan","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2010.01.004_bib28","doi-asserted-by":"crossref","first-page":"e12","DOI":"10.1017\/S1462399408000665","article-title":"Molecular mechanisms of antibody-mediated neutralisation of flavivirus infection","volume":"10","author":"Pierson","year":"2008","journal-title":"Expert Rev. Mol. Med."},{"key":"10.1016\/j.chom.2010.01.004_bib29","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.chom.2007.03.002","article-title":"The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection","volume":"1","author":"Pierson","year":"2007","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.chom.2010.01.004_bib30","doi-asserted-by":"crossref","first-page":"8411","DOI":"10.1128\/JVI.00611-08","article-title":"A mouse-passaged dengue virus strain with reduced affinity for heparan sulfate causes severe disease in mice by establishing increased systemic viral loads","volume":"82","author":"Prestwood","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.chom.2010.01.004_bib31","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1086\/517587","article-title":"Dengue virus evolution and virulence models","volume":"44","author":"Rico-Hesse","year":"2007","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.chom.2010.01.004_bib32","doi-asserted-by":"crossref","first-page":"720","DOI":"10.4269\/ajtmh.1999.61.720","article-title":"Detection of dengue virus RNA by reverse transcription-polymerase chain reaction in the liver and lymphoid organs but not in the brain in fatal human infection","volume":"61","author":"Rosen","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.chom.2010.01.004_bib33","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0065-3527(03)60010-2","article-title":"Immunology and immunopathogenesis of dengue disease","volume":"60","author":"Rothman","year":"2003","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.chom.2010.01.004_bib34","doi-asserted-by":"crossref","first-page":"10208","DOI":"10.1128\/JVI.00062-06","article-title":"Murine model for dengue virus-induced lethal disease with increased vascular permeability","volume":"80","author":"Shresta","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.chom.2010.01.004_bib35","doi-asserted-by":"crossref","first-page":"4185","DOI":"10.4049\/jimmunol.145.12.4185","article-title":"Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice","volume":"145","author":"Starnes","year":"1990","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.chom.2010.01.004_bib36","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1084\/jem.20021840","article-title":"DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells","volume":"197","author":"Tassaneetrithep","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.chom.2010.01.004_bib37","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/ni.1622","article-title":"Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5","volume":"9","author":"Uematsu","year":"2008","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.chom.2010.01.004_bib38","first-page":"518","article-title":"Prospects for a dengue virus vaccine","volume":"5","author":"Whitehead","year":"2007","journal-title":"Nat. Rev."},{"key":"10.1016\/j.chom.2010.01.004_bib39","doi-asserted-by":"crossref","first-page":"3363","DOI":"10.1128\/JVI.75.7.3363-3370.2001","article-title":"Single amino acid substitution in the V protein of simian virus 5 differentiates its ability to block interferon signaling in human and murine cells","volume":"75","author":"Young","year":"2001","journal-title":"J. Virol."}],"container-title":["Cell Host & Microbe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312810000302?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312810000302?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T12:10:20Z","timestamp":1761826220000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931312810000302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S1931312810000302"],"URL":"https:\/\/doi.org\/10.1016\/j.chom.2010.01.004","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.2846956.2511054","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.2846956.3600055","asserted-by":"object"}]},"ISSN":["1931-3128"],"issn-type":[{"value":"1931-3128","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhanced Infection of Liver Sinusoidal Endothelial Cells in a Mouse Model of Antibody-Induced Severe Dengue Disease","name":"articletitle","label":"Article Title"},{"value":"Cell Host & Microbe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chom.2010.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}