{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:35:45Z","timestamp":1790123745926,"version":"4.0.1"},"reference-count":67,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T00:00:00Z","timestamp":1544659200000},"content-version":"vor","delay-in-days":377,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100007197","name":"USPHS","doi-asserted-by":"publisher","award":["R01CA025235"],"award-info":[{"award-number":["R01CA025235"]}],"id":[{"id":"10.13039\/100007197","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007197","name":"USPHS","doi-asserted-by":"publisher","award":["T32AI060567"],"award-info":[{"award-number":["T32AI060567"]}],"id":[{"id":"10.13039\/100007197","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Philip Whitcome Fellowship"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Host & Microbe"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.chom.2017.11.008","type":"journal-article","created":{"date-parts":[[2017,12,13]],"date-time":"2017-12-13T16:34:00Z","timestamp":1513182840000},"page":"789-800.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling"],"prefix":"10.1016","volume":"22","author":[{"given":"Nathan R.","family":"Zemke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold J.","family":"Berk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chom.2017.11.008_bib1","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.virol.2004.08.007","article-title":"Comprehensive sequence analysis of the E1A proteins of human and simian adenoviruses","volume":"329","author":"Avvakumov","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.chom.2017.11.008_bib2","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/nrd2422","article-title":"Interferons at age 50: past, current and future impact on biomedicine","volume":"6","author":"Borden","year":"2007","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.chom.2017.11.008_bib3","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/j.1460-2075.1993.tb05679.x","article-title":"A region in the C-terminus of adenovirus 2\/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis","volume":"12","author":"Boyd","year":"1993","journal-title":"EMBO J."},{"key":"10.1016\/j.chom.2017.11.008_bib4","first-page":"67","article-title":"Transformation by human adenoviruses","volume":"780","author":"Branton","year":"1985","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.chom.2017.11.008_bib5","doi-asserted-by":"crossref","first-page":"9373","DOI":"10.1073\/pnas.0903487106","article-title":"Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes","volume":"106","author":"Cheon","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.11.008_bib6","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1038\/emboj.2013.203","article-title":"IFN\u03b2-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage","volume":"32","author":"Cheon","year":"2013","journal-title":"EMBO J."},{"key":"10.1016\/j.chom.2017.11.008_bib7","doi-asserted-by":"crossref","first-page":"10348","DOI":"10.1128\/JVI.00786-13","article-title":"Dissection of the C-terminal region of E1A redefines the roles of CtBP and other cellular targets in oncogenic transformation","volume":"87","author":"Cohen","year":"2013","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib8","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1126\/science.8197455","article-title":"Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins","volume":"264","author":"Darnell","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.chom.2017.11.008_bib9","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1101\/gad.7.4.546","article-title":"Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B","volume":"7","author":"Debbas","year":"1993","journal-title":"Genes Dev."},{"key":"10.1016\/j.chom.2017.11.008_bib10","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.molcel.2014.12.026","article-title":"Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase","volume":"57","author":"Di Vona","year":"2015","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chom.2017.11.008_bib11","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/0076-6879(83)01039-3","article-title":"Eukaryotic gene transcription with purified components","volume":"101","author":"Dignam","year":"1983","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.chom.2017.11.008_bib12","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1128\/JVI.63.2.987-991.1989","article-title":"Phosphorylation at serine 89 induces a shift in gel mobility but has little effect on the function of adenovirus type 5 E1A proteins","volume":"63","author":"Dumont","year":"1989","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib13","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0014-5793(01)03294-X","article-title":"The FHA domain","volume":"513","author":"Durocher","year":"2002","journal-title":"FEBS Lett."},{"key":"10.1016\/j.chom.2017.11.008_bib14","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.chom.2014.10.004","article-title":"Adenovirus small E1A employs the lysine acetylases p300\/CBP and tumor suppressor Rb to repress select host genes and promote productive virus infection","volume":"16","author":"Ferrari","year":"2014","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.chom.2017.11.008_bib15","doi-asserted-by":"crossref","first-page":"13260","DOI":"10.1073\/pnas.0906770106","article-title":"Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein","volume":"106","author":"Ferreon","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.11.008_bib16","first-page":"e27521","article-title":"STAT2 and IRF9: beyond ISGF3","volume":"2","author":"Fink","year":"2013","journal-title":"JAKSTAT"},{"key":"10.1016\/j.chom.2017.11.008_bib17","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.chom.2012.05.005","article-title":"Adenovirus evasion of interferon-mediated innate immunity by direct antagonism of a cellular histone posttranslational modification","volume":"11","author":"Fonseca","year":"2012","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.chom.2017.11.008_bib18","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.celrep.2013.07.043","article-title":"Extensive cooperation of immune master regulators IRF3 and NF\u03baB in RNA Pol II recruitment and pause release in human innate antiviral transcription","volume":"4","author":"Freaney","year":"2013","journal-title":"Cell Rep."},{"key":"10.1016\/j.chom.2017.11.008_bib19","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/nrm827","article-title":"Adenovirus-5 E1A: paradox and paradigm","volume":"3","author":"Frisch","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.chom.2017.11.008_bib20","doi-asserted-by":"crossref","first-page":"5416","DOI":"10.1073\/pnas.100501197","article-title":"Myogenic stem cell function is impaired in mice lacking the forkhead\/winged helix protein MNF","volume":"97","author":"Garry","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.11.008_bib21","doi-asserted-by":"crossref","first-page":"28241","DOI":"10.1038\/srep28241","article-title":"The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2","volume":"6","author":"Glenewinkel","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.chom.2017.11.008_bib22","doi-asserted-by":"crossref","first-page":"3079","DOI":"10.1091\/mbc.e11-02-0170","article-title":"Live-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control","volume":"23","author":"Grant","year":"2012","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.chom.2017.11.008_bib23","doi-asserted-by":"crossref","first-page":"4568","DOI":"10.1073\/pnas.0830998100","article-title":"C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs","volume":"100","author":"Grooteclaes","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.11.008_bib24","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1128\/JVI.71.3.1842-1849.1997","article-title":"Construction of adenovirus vectors through Cre-lox recombination","volume":"71","author":"Hardy","year":"1997","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib25","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1128\/JVI.55.3.533-546.1985","article-title":"Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products","volume":"55","author":"Harlow","year":"1985","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib26","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.molcel.2010.05.004","article-title":"Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities","volume":"38","author":"Heinz","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chom.2017.11.008_bib27","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1126\/science.1155544","article-title":"Adenovirus small e1a alters global patterns of histone modification","volume":"321","author":"Horwitz","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.chom.2017.11.008_bib28","doi-asserted-by":"crossref","first-page":"5883","DOI":"10.1073\/pnas.87.15.5883","article-title":"Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis","volume":"87","author":"Howe","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.11.008_bib29","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1101\/sqb.2013.78.020321","article-title":"The IRF family transcription factors at the interface of innate and adaptive immune responses","volume":"78","author":"Ikushima","year":"2013","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"10.1016\/j.chom.2017.11.008_bib30","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.molcel.2006.08.010","article-title":"A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1","volume":"23","author":"Jin","year":"2006","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chom.2017.11.008_bib31","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/0092-8674(79)90275-7","article-title":"Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells","volume":"17","author":"Jones","year":"1979","journal-title":"Cell"},{"key":"10.1016\/j.chom.2017.11.008_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0042-6822(86)90366-1","article-title":"Induction of cellular DNA synthesis by purified adenovirus E1A proteins","volume":"152","author":"Kaczmarek","year":"1986","journal-title":"Virology"},{"key":"10.1016\/j.chom.2017.11.008_bib33","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1128\/MCB.6.5.1487","article-title":"A novel general approach to eucaryotic mutagenesis functionally identifies conserved regions within the adenovirus 13S E1A polypeptide","volume":"6","author":"Kimelman","year":"1986","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.chom.2017.11.008_bib34","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1128\/JVI.02119-09","article-title":"Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1\/K2 transcription factors","volume":"84","author":"Komorek","year":"2010","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib35","doi-asserted-by":"crossref","first-page":"4143","DOI":"10.1242\/jcs.113.23.4143","article-title":"The FHA domain mediates phosphoprotein interactions","volume":"113","author":"Li","year":"2000","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.chom.2017.11.008_bib36","doi-asserted-by":"crossref","first-page":"2986","DOI":"10.1128\/MCB.18.5.2986","article-title":"Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation","volume":"18","author":"Lin","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.chom.2017.11.008_bib37","doi-asserted-by":"crossref","first-page":"11455","DOI":"10.1073\/pnas.88.24.11455","article-title":"High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons","volume":"88","author":"McKendry","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.11.008_bib38","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1016\/j.bbamcr.2011.06.023","article-title":"DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation","volume":"1813","author":"Miyata","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.chom.2017.11.008_bib39","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/0092-8674(84)90045-X","article-title":"Complete transformation by adenovirus 2 requires both E1A proteins","volume":"36","author":"Montell","year":"1984","journal-title":"Cell"},{"key":"10.1016\/j.chom.2017.11.008_bib40","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1534\/genetics.113.154211","article-title":"The Drosophila wings apart gene anchors a novel, evolutionarily conserved pathway of neuromuscular development","volume":"195","author":"Morriss","year":"2013","journal-title":"Genetics"},{"key":"10.1016\/j.chom.2017.11.008_bib41","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1471-213X-6-28","article-title":"A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression","volume":"6","author":"Nissen","year":"2006","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.chom.2017.11.008_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/JVI.02484-16","article-title":"Suppression of type I interferon signaling by E1A via RuvBL1\/Pontin","volume":"91","author":"Olanubi","year":"2017","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib43","doi-asserted-by":"crossref","first-page":"e02509-14","DOI":"10.1128\/mBio.02509-14","article-title":"The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression","volume":"6","author":"Panda","year":"2015","journal-title":"MBio"},{"key":"10.1016\/j.chom.2017.11.008_bib44","doi-asserted-by":"crossref","first-page":"7252","DOI":"10.1128\/JVI.00104-08","article-title":"Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes","volume":"82","author":"Pelka","year":"2008","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib45","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1038\/281694a0","article-title":"Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses","volume":"281","author":"Perricaudet","year":"1979","journal-title":"Nature"},{"key":"10.1016\/j.chom.2017.11.008_bib46","doi-asserted-by":"crossref","first-page":"6683","DOI":"10.1073\/pnas.96.12.6683","article-title":"ZEB represses transcription through interaction with the corepressor CtBP","volume":"96","author":"Postigo","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.11.008_bib47","doi-asserted-by":"crossref","first-page":"8159","DOI":"10.1128\/MCB.00680-06","article-title":"Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins","volume":"26","author":"Quinlan","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.chom.2017.11.008_bib48","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.1038\/emboj.2010.251","article-title":"The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions","volume":"29","author":"Ritterhoff","year":"2010","journal-title":"EMBO J."},{"key":"10.1016\/j.chom.2017.11.008_bib49","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1038\/304602a0","article-title":"Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture","volume":"304","author":"Ruley","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.chom.2017.11.008_bib50","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/nrc3556","article-title":"The DREAM complex: master coordinator of cell cycle-dependent gene expression","volume":"13","author":"Sadasivam","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.chom.2017.11.008_bib51","doi-asserted-by":"crossref","first-page":"10467","DOI":"10.1073\/pnas.92.23.10467","article-title":"Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation","volume":"92","author":"Schaeper","year":"1995","journal-title":"Proc.\u00a0Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.11.008_bib52","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.coviro.2014.03.006","article-title":"Interferon-stimulated genes: roles in viral pathogenesis","volume":"6","author":"Schoggins","year":"2014","journal-title":"Curr. Opin. Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib53","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0092-8674(00)81902-9","article-title":"Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a","volume":"88","author":"Serrano","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.chom.2017.11.008_bib54","first-page":"41","article-title":"The Down syndrome critical region","volume":"57","author":"Shapiro","year":"1999","journal-title":"J.\u00a0Neural Transm. Suppl."},{"key":"10.1016\/j.chom.2017.11.008_bib55","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/nature01550","article-title":"Coordinated histone modifications mediated by a CtBP co-repressor complex","volume":"422","author":"Shi","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.chom.2017.11.008_bib56","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1002\/j.1460-2075.1985.tb03934.x","article-title":"The release of growth arrest by microinjection of adenovirus E1A DNA","volume":"4","author":"Stabel","year":"1985","journal-title":"EMBO J."},{"key":"10.1016\/j.chom.2017.11.008_bib57","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.cytogfr.2007.06.013","article-title":"How cells respond to interferons revisited: from early history to current complexity","volume":"18","author":"Stark","year":"2007","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.chom.2017.11.008_bib58","first-page":"1171","article-title":"Requirement of the C-terminal region of adenovirus E1a for cell transformation in cooperation with E1b","volume":"6","author":"Subramanian","year":"1991","journal-title":"Oncogene"},{"key":"10.1016\/j.chom.2017.11.008_bib59","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S1097-2765(01)00301-X","article-title":"Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin","volume":"8","author":"Suka","year":"2001","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chom.2017.11.008_bib60","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0896-6273(95)90286-4","article-title":"minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila","volume":"14","author":"Tejedor","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.chom.2017.11.008_bib61","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1128\/JVI.59.1.14-22.1986","article-title":"Genetic mapping of a major site of phosphorylation in adenovirus type 2 E1A proteins","volume":"59","author":"Tsukamoto","year":"1986","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib62","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.celrep.2013.03.027","article-title":"The protein interaction landscape of the human CMGC kinase group","volume":"3","author":"Varjosalo","year":"2013","journal-title":"Cell Rep."},{"key":"10.1016\/j.chom.2017.11.008_bib63","doi-asserted-by":"crossref","first-page":"7917","DOI":"10.1128\/JVI.69.12.7917-7924.1995","article-title":"E1A promotes association between p300 and pRB in multimeric complexes required for normal biological activity","volume":"69","author":"Wang","year":"1995","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.11.008_bib64","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1002\/j.1460-2075.1984.tb02066.x","article-title":"Dissection of overlapping functions within the adenovirus type 5 E1A gene","volume":"3","author":"Winberg","year":"1984","journal-title":"EMBO J."},{"key":"10.1016\/j.chom.2017.11.008_bib65","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.immuni.2010.11.027","article-title":"The ubiquitin E3 ligase RAUL negatively regulates type I interferon through ubiquitination of the transcription factors IRF7 and IRF3","volume":"33","author":"Yu","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.chom.2017.11.008_bib66","doi-asserted-by":"crossref","first-page":"7544","DOI":"10.1038\/sj.onc.1210569","article-title":"PLDLS-dependent interaction of E1A with CtBP: regulation of CtBP nuclear localization and transcriptional functions","volume":"26","author":"Zhao","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.chom.2017.11.008_bib67","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.virol.2014.04.006","article-title":"A new look at adenovirus splicing","volume":"456-457","author":"Zhao","year":"2014","journal-title":"Virology"}],"container-title":["Cell Host & Microbe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312817305024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312817305024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T12:35:34Z","timestamp":1660134934000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931312817305024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":67,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["S1931312817305024"],"URL":"https:\/\/doi.org\/10.1016\/j.chom.2017.11.008","relation":{},"ISSN":["1931-3128"],"issn-type":[{"value":"1931-3128","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling","name":"articletitle","label":"Article Title"},{"value":"Cell Host & Microbe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chom.2017.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}