{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:45:19Z","timestamp":1792813519575,"version":"4.5.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T00:00:00Z","timestamp":1547078400000},"content-version":"vor","delay-in-days":374,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"ERC","award":["310372"],"award-info":[{"award-number":["310372"]}]},{"name":"Netherlands Organization for Scientific Research","award":["016.176.006"],"award-info":[{"award-number":["016.176.006"]}],"id":[{"id":"https:\/\/ror.org\/04jsz6e67","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000925","name":"NHMRC","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Danish National Research Foundation","award":["DNRF108"],"award-info":[{"award-number":["DNRF108"]}],"id":[{"id":"https:\/\/ror.org\/00znyv691","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Host &amp; Microbe"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.chom.2017.12.010","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T11:34:39Z","timestamp":1515584079000},"page":"89-100.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1132,"title":["BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity"],"prefix":"10.1016","volume":"23","author":[{"given":"Rob J.W.","family":"Arts","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone J.C.F.M.","family":"Moorlag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Novakovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang-Yin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marije","family":"Oosting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramnik J.","family":"Xavier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cisca","family":"Wijmenga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo A.B.","family":"Joosten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal B.E.M.","family":"Reusken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine S.","family":"Benn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Aaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion P.","family":"Koopmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik G.","family":"Stunnenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinout","family":"van Crevel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihai G.","family":"Netea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chom.2017.12.010_bib1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/infdis\/jir240","article-title":"Randomized trial of BCG vaccination at birth to low-birth-weight children: beneficial nonspecific effects in the neonatal period?","volume":"204","author":"Aaby","year":"2011","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.chom.2017.12.010_bib2","doi-asserted-by":"crossref","first-page":"R106","DOI":"10.1186\/gb-2010-11-10-r106","article-title":"Differential expression analysis for sequence count data","volume":"11","author":"Anders","year":"2010","journal-title":"Genome Biol."},{"key":"10.1016\/j.chom.2017.12.010_bib3","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1189\/jlb.4MA0215-059R","article-title":"Long-term in\u00a0vitro and in\u00a0vivo effects of \u03b3-irradiated BCG on innate and adaptive immunity","volume":"98","author":"Arts","year":"2015","journal-title":"J.\u00a0Leukoc. Biol."},{"key":"10.1016\/j.chom.2017.12.010_bib4","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1016\/j.celrep.2016.11.011","article-title":"Immunometabolic Pathways in BCG-Induced Trained Immunity","volume":"17","author":"Arts","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.chom.2017.12.010_bib5","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/978-1-4615-3434-1_26","article-title":"Stimulation of host-defense mechanism with synthetic adjuvants and recombinant cytokines against viral infection in mice","volume":"319","author":"Azuma","year":"1992","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.chom.2017.12.010_bib6","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/bioinformatics\/btr174","article-title":"BamTools: a C++ API and toolkit for analyzing and managing BAM files","volume":"27","author":"Barnett","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.chom.2017.12.010_bib7","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1161\/ATVBAHA.114.303887","article-title":"Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes","volume":"34","author":"Bekkering","year":"2014","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.chom.2017.12.010_bib8","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1128\/CVI.00349-16","article-title":"In\u00a0vitro experimental model of trained innate immunity in human primary monocytes","volume":"23","author":"Bekkering","year":"2016","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.chom.2017.12.010_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2017.11.025","article-title":"Metabolic induction of trained immunity through the mevalonate pathway","volume":"172","author":"Bekkering","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.chom.2017.12.010_bib10","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1002\/1521-4141(2002010)32:10<2807::AID-IMMU2807>3.0.CO;2-0","article-title":"Contribution of CD8+ T\u00a0cells to innate immunity: IFN-gamma secretion induced by IL-12 and IL-18","volume":"32","author":"Berg","year":"2002","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.chom.2017.12.010_bib11","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1084\/jem.20031051","article-title":"Memory CD8+ T\u00a0cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen","volume":"198","author":"Berg","year":"2003","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.chom.2017.12.010_bib12","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/INF.0b013e3182458289","article-title":"Small randomized trial among low-birth-weight children receiving bacillus Calmette-Gu\u00e9rin vaccination at first health center contact","volume":"31","author":"Biering-S\u00f8rensen","year":"2012","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.chom.2017.12.010_bib13","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1016\/j.vaccine.2015.02.056","article-title":"Variation of growth in the production of the BCG vaccine and the association with the immune response. An observational study within a randomised trial","volume":"33","author":"Biering-S\u00f8rensen","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.chom.2017.12.010_bib14","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1189\/jlb.5RI0315-096R","article-title":"Trained innate immunity as underlying mechanism for the long-term, nonspecific effects of vaccines","volume":"98","author":"Blok","year":"2015","journal-title":"J.\u00a0Leukoc. Biol."},{"key":"10.1016\/j.chom.2017.12.010_bib15","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1128\/CVI.00162-15","article-title":"Mycobacterium bovis BCG vaccination induces divergent proinflammatory or regulatory T\u00a0cell responses in adults","volume":"22","author":"Boer","year":"2015","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.chom.2017.12.010_bib16","doi-asserted-by":"crossref","first-page":"1250684","DOI":"10.1126\/science.1250684","article-title":"mTOR- and HIF-1\u03b1-mediated aerobic glycolysis as metabolic basis for trained immunity","volume":"345","author":"Cheng","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.chom.2017.12.010_bib17","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1038\/ni.3398","article-title":"Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis","volume":"17","author":"Cheng","year":"2016","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.chom.2017.12.010_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2017.12.013","article-title":"Western diet\u00a0triggers NLRP3-dependent innate immune reprogramming","volume":"172","author":"Christ","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.chom.2017.12.010_bib19","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1001\/jama.1994.03510330076038","article-title":"Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature","volume":"271","author":"Colditz","year":"1994","journal-title":"JAMA"},{"issue":"5, Suppl 27","key":"10.1016\/j.chom.2017.12.010_bib20","first-page":"S1","article-title":"The IL-1 family and inflammatory diseases","volume":"20","author":"Dinarello","year":"2002","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.chom.2017.12.010_bib21","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1128\/JCM.40.7.2323-2330.2002","article-title":"Rapid detection and quantification of RNA of Ebola and Marburg viruses, Lassa virus, Crimean-Congo hemorrhagic fever virus, Rift Valley fever virus, dengue virus, and yellow fever virus by real-time reverse transcription-PCR","volume":"40","author":"Drosten","year":"2002","journal-title":"J.\u00a0Clin. Microbiol."},{"key":"10.1016\/j.chom.2017.12.010_bib22","doi-asserted-by":"crossref","first-page":"172","DOI":"10.4269\/ajtmh.2012.12-0179","article-title":"A randomized, double-blind, controlled trial of the 17D yellow fever virus vaccine given in combination with immune globulin or placebo: comparative viremia and immunogenicity","volume":"88","author":"Edupuganti","year":"2013","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.chom.2017.12.010_bib23","doi-asserted-by":"crossref","first-page":"2782","DOI":"10.1016\/S0264-410X(03)00181-6","article-title":"BCG scar and positive tuberculin reaction associated with reduced child mortality in West Africa. A non-specific beneficial effect of BCG?","volume":"21","author":"Garly","year":"2003","journal-title":"Vaccine"},{"key":"10.1016\/j.chom.2017.12.010_bib24","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.urology.2005.12.014","article-title":"Can intravesical bacillus Calmette-Gu\u00e9rin reduce recurrence in patients with superficial bladder cancer? A meta-analysis of randomized trials","volume":"67","author":"Han","year":"2006","journal-title":"Urology"},{"key":"10.1016\/j.chom.2017.12.010_bib25","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.molcel.2010.05.004","article-title":"Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities","volume":"38","author":"Heinz","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chom.2017.12.010_bib26","doi-asserted-by":"crossref","first-page":"7300","DOI":"10.1016\/j.vaccine.2012.09.035","article-title":"Non-specific and sex-differential effects of vaccinations on child survival in rural western India","volume":"30","author":"Hirve","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.chom.2017.12.010_bib27","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.chom.2017.12.010_bib28","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0264-410X(89)90234-X","article-title":"Protective activity of recombinant cytokines against Sendai virus and herpes simplex virus (HSV) infections in mice","volume":"7","author":"Iida","year":"1989","journal-title":"Vaccine"},{"key":"10.1016\/j.chom.2017.12.010_bib29","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1093\/infdis\/jiu508","article-title":"Heterologous immunological effects of early BCG vaccination in low-birth-weight infants in Guinea-Bissau: a randomized-controlled trial","volume":"211","author":"Jensen","year":"2015","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.chom.2017.12.010_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2017.12.031","article-title":"BCG educates hematopoietic stem cells to generate protective innate immunity against tuberculosis","volume":"172","author":"Kaufmann","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.chom.2017.12.010_bib31","doi-asserted-by":"crossref","first-page":"17537","DOI":"10.1073\/pnas.1202870109","article-title":"Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes","volume":"109","author":"Kleinnijenhuis","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.12.010_bib32","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1159\/000355628","article-title":"Long-lasting effects of BCG vaccination on both heterologous Th1\/Th17 responses and innate trained immunity","volume":"6","author":"Kleinnijenhuis","year":"2014","journal-title":"J.\u00a0Innate Immun."},{"key":"10.1016\/j.chom.2017.12.010_bib33","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1136\/bmj.321.7274.1435","article-title":"Routine vaccinations and child survival: follow up study in Guinea-Bissau, West Africa","volume":"321","author":"Kristensen","year":"2000","journal-title":"BMJ"},{"key":"10.1016\/j.chom.2017.12.010_bib34","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1093\/infdis\/jiv332","article-title":"BCG vaccination enhances the immunogenicity of subsequent influenza vaccination in healthy volunteers: a randomized, placebo-controlled pilot study","volume":"212","author":"Leentjens","year":"2015","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.chom.2017.12.010_bib35","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.4049\/jimmunol.166.2.1097","article-title":"Bystander activation of CD8+ T\u00a0cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens","volume":"166","author":"Lertmemongkolchai","year":"2001","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.chom.2017.12.010_bib36","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1093\/bioinformatics\/btp324","article-title":"Fast and accurate short read alignment with Burrows-Wheeler transform","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.chom.2017.12.010_bib37","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The Sequence Alignment\/Map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.chom.2017.12.010_bib38","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/nm.4139","article-title":"Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi","volume":"22","author":"Li","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.chom.2017.12.010_bib39","doi-asserted-by":"crossref","first-page":"3528","DOI":"10.1128\/JVI.02393-08","article-title":"CD4 T-cell-mediated heterologous immunity between mycobacteria and poxviruses","volume":"83","author":"Mathurin","year":"2009","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.chom.2017.12.010_bib40","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/nbt.1630","article-title":"GREAT improves functional interpretation of cis-regulatory regions","volume":"28","author":"McLean","year":"2010","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.chom.2017.12.010_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2017.11.034","article-title":"Modulation of myelopoiesis progenitors is an integral component of trained immunity","volume":"172","author":"Mitroulis","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.chom.2017.12.010_bib42","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1111\/j.1365-3156.2005.01434.x","article-title":"Evaluation of non-specific effects of infant immunizations on early infant mortality in a southern Indian population","volume":"10","author":"Moulton","year":"2005","journal-title":"Trop. Med. Int. Health"},{"key":"10.1016\/j.chom.2017.12.010_bib43","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S1471-4906(03)00079-6","article-title":"Proinflammatory cytokines and sepsis syndrome: not enough, or too much of a good thing?","volume":"24","author":"Netea","year":"2003","journal-title":"Trends Immunol."},{"key":"10.1016\/j.chom.2017.12.010_bib44","doi-asserted-by":"crossref","first-page":"aaf1098","DOI":"10.1126\/science.aaf1098","article-title":"Trained immunity: a program of innate immune memory in health and disease","volume":"352","author":"Netea","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.chom.2017.12.010_bib45","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/j.cell.2016.09.034","article-title":"\u03b2-Glucan reverses the epigenetic state of LPS-induced immunological tolerance","volume":"167","author":"Novakovic","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.chom.2017.12.010_bib46","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1097\/01.inf.0000129693.81082.a0","article-title":"Low birth weight infants and Calmette-Gu\u00e9rin bacillus vaccination at birth: community study from Guinea-Bissau","volume":"23","author":"Roth","year":"2004","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.chom.2017.12.010_bib47","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/ije\/dyh392","article-title":"BCG vaccination scar associated with better childhood survival in Guinea-Bissau","volume":"34","author":"Roth","year":"2005","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.chom.2017.12.010_bib48","doi-asserted-by":"crossref","first-page":"1251086","DOI":"10.1126\/science.1251086","article-title":"Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity","volume":"345","author":"Saeed","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.chom.2017.12.010_bib49","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1086\/520094","article-title":"Tumor necrosis factor-alpha and interleukin-1 beta play a critical role in the resistance against lethal herpes simplex virus encephalitis","volume":"196","author":"Sergerie","year":"2007","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.chom.2017.12.010_bib50","doi-asserted-by":"crossref","first-page":"R13","DOI":"10.1186\/gb-2011-12-2-r13","article-title":"Haplotype and isoform specific expression estimation using multi-mapping RNA-seq reads","volume":"12","author":"Turro","year":"2011","journal-title":"Genome Biol."},{"key":"10.1016\/j.chom.2017.12.010_bib51","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1073\/pnas.85.5.1620","article-title":"A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection","volume":"85","author":"van der Meer","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2017.12.010_bib52","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/nri.2017.36","article-title":"The immunopathology of sepsis and potential therapeutic targets","volume":"17","author":"van der Poll","year":"2017","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.chom.2017.12.010_bib53","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/01.shk.0000223125.56888.c7","article-title":"Effects of haplotypes in the interleukin 1beta promoter on lipopolysaccharide-induced interleukin 1beta expression","volume":"26","author":"Wen","year":"2006","journal-title":"Shock"},{"key":"10.1016\/j.chom.2017.12.010_bib54","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1093\/infdis\/jiu636","article-title":"IL1B and DEFB1 polymorphisms increase susceptibility to invasive mold infection after solid-organ transplantation","volume":"211","author":"W\u00f3jtowicz","year":"2015","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.chom.2017.12.010_bib55","doi-asserted-by":"crossref","first-page":"30488","DOI":"10.2807\/1560-7917.ES.2017.22.11.30488","article-title":"Yellow fever in a traveller returning from Suriname to the Netherlands, March 2017","volume":"22","author":"Wouthuyzen-Bakker","year":"2017","journal-title":"Euro Surveill."},{"key":"10.1016\/j.chom.2017.12.010_bib56","doi-asserted-by":"crossref","first-page":"R137","DOI":"10.1186\/gb-2008-9-9-r137","article-title":"Model-based analysis of ChIP-Seq (MACS)","volume":"9","author":"Zhang","year":"2008","journal-title":"Genome Biol."},{"key":"10.1016\/j.chom.2017.12.010_bib57","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1056\/NEJMra1200894","article-title":"Tuberculosis","volume":"368","author":"Zumla","year":"2013","journal-title":"N.\u00a0Engl. J. Med."}],"container-title":["Cell Host &amp; Microbe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312817305462?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312817305462?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T05:42:02Z","timestamp":1565329322000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931312817305462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":57,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S1931312817305462"],"URL":"https:\/\/doi.org\/10.1016\/j.chom.2017.12.010","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.732450556.793565370","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.732450556.793546130","asserted-by":"object"}]},"ISSN":["1931-3128"],"issn-type":[{"value":"1931-3128","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity","name":"articletitle","label":"Article Title"},{"value":"Cell Host & Microbe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chom.2017.12.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2017.11.034","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2017.12.013","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2017.12.031","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2017.11.025","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}