{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T00:32:44Z","timestamp":1762561964034,"version":"build-2065373602"},"reference-count":10,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472288"],"award-info":[{"award-number":["82472288"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2306200"],"award-info":[{"award-number":["2023YFC2306200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Host &amp; Microbe"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.chom.2025.03.002","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T10:36:38Z","timestamp":1744194998000},"page":"464-466","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["QDS pathoblockers target and lock \u03b1-hemolysin"],"prefix":"10.1016","volume":"33","author":[{"given":"Yanan","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.chom.2025.03.002_bib1","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.chom.2025.03.002_bib2","doi-asserted-by":"crossref","DOI":"10.1172\/JCI185824","article-title":"Intertwining clonality and resistance: Staphylococcus aureus in the antibiotic era","volume":"134","author":"Chambers","year":"2024","journal-title":"J.\u00a0Clin. Investig."},{"key":"10.1016\/j.chom.2025.03.002_bib3","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20240002","article-title":"A path forward for Staphylococcus aureus vaccine development","volume":"221","author":"Fritz","year":"2024","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.chom.2025.03.002_bib4","doi-asserted-by":"crossref","DOI":"10.1128\/aac.02071-21","article-title":"Considerations for the Use of Phage Therapy in Clinical Practice","volume":"66","author":"Suh","year":"2022","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.chom.2025.03.002_bib5","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nrmicro.2015.3","article-title":"Pore-forming toxins: ancient, but never really out of fashion","volume":"14","author":"Dal Peraro","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.chom.2025.03.002_bib6","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.3390\/toxins5061140","article-title":"Staphylococcus aureus \u03b1-toxin: nearly a century of intrigue","volume":"5","author":"Berube","year":"2013","journal-title":"Toxins"},{"key":"10.1016\/j.chom.2025.03.002_bib7","doi-asserted-by":"crossref","first-page":"9835","DOI":"10.1038\/s41467-024-53979-8","article-title":"Post-translational toxin modification by lactate controls Staphylococcus aureus virulence","volume":"15","author":"Wang","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.chom.2025.03.002_bib8","first-page":"153","article-title":"Exhausted local lactate accumulation via injectable nanozyme-functionalized hydrogel microsphere for inflammation relief and tissue regeneration","volume":"12","author":"Shen","year":"2022","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.chom.2025.03.002_bib9","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aad9922","article-title":"Staphylococcus aureus \u03b1 toxin potentiates opportunistic bacterial lung infections","volume":"8","author":"Cohen","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.chom.2025.03.002_bib10","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.chom.2025.03.006","article-title":"Highly potent quinoxalinediones inhibit \u03b1-hemolysin and ameliorate lung infections by Staphylococcus aureus","volume":"33","author":"Shekhar","year":"2015","journal-title":"Cell Host Microbe"}],"container-title":["Cell Host &amp; Microbe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193131282500085X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193131282500085X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T00:27:46Z","timestamp":1762561666000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S193131282500085X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S193131282500085X"],"URL":"https:\/\/doi.org\/10.1016\/j.chom.2025.03.002","relation":{},"ISSN":["1931-3128"],"issn-type":[{"type":"print","value":"1931-3128"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"QDS pathoblockers target and lock \u03b1-hemolysin","name":"articletitle","label":"Article Title"},{"value":"Cell Host & Microbe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chom.2025.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}