{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T20:59:26Z","timestamp":1776286766987,"version":"3.50.1"},"reference-count":9,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","award":["K08 K08AI159384"],"award-info":[{"award-number":["K08 K08AI159384"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Host &amp; Microbe"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.chom.2026.03.007","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T16:24:45Z","timestamp":1775665485000},"page":"551-553","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Don\u2019t keep this endopeptidase on the DL"],"prefix":"10.1016","volume":"34","author":[{"given":"Jaeden D.","family":"Flury","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1568-7733","authenticated-orcid":false,"given":"Drew J.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.chom.2026.03.007_bib2","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jpeds.2011.05.033","article-title":"Prolonged initial empirical antibiotic treatment is associated with adverse outcomes in premature infants","volume":"159","author":"Kuppala","year":"2011","journal-title":"J. Pediatr."},{"key":"10.1016\/j.chom.2026.03.007_bib1","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.chom.2026.02.004","article-title":"Gut microbiota immaturity with DL-endopeptidase deficiency links antibiotic use to preterm late-onset sepsis","volume":"34","author":"Shen","year":"2026","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.chom.2026.03.007_bib3","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1016\/j.chom.2024.07.027","article-title":"Clinical sequelae of gut microbiome development and disruption in hospitalized preterm infants","volume":"32","author":"Th\u00e4nert","year":"2024","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.chom.2026.03.007_bib4","doi-asserted-by":"crossref","first-page":"eadg5562","DOI":"10.1126\/scitranslmed.adg5562","article-title":"Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit","volume":"15","author":"Schwartz","year":"2023","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.chom.2026.03.007_bib5","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1126\/science.abj2972","article-title":"Robust variation in infant gut microbiome assembly across a spectrum of lifestyles","volume":"376","author":"Olm","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.chom.2026.03.007_bib6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s41390-018-0022-z","article-title":"The premature infant gut microbiome during the first 6 weeks of life differs based on gestational maturity at birth","volume":"84","author":"Chernikova","year":"2018","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.chom.2026.03.007_bib7","article-title":"Progression of gut microbiome in preterm infants during the first three months","volume":"15","author":"Li","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.chom.2026.03.007_bib8","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.chom.2022.08.002","article-title":"Gut microbial DL-endopeptidase alleviates Crohn\u2019s disease via the NOD2 pathway","volume":"30","author":"Gao","year":"2022","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.chom.2026.03.007_bib9","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2024-069102","article-title":"Effectiveness and Risks of Probiotics in Preterm Infants","volume":"155","author":"Alshaikh","year":"2025","journal-title":"Pediatrics"}],"container-title":["Cell Host &amp; Microbe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312826001150?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312826001150?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T20:26:42Z","timestamp":1776284802000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931312826001150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S1931312826001150"],"URL":"https:\/\/doi.org\/10.1016\/j.chom.2026.03.007","relation":{},"ISSN":["1931-3128"],"issn-type":[{"value":"1931-3128","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Don\u2019t keep this endopeptidase on the DL","name":"articletitle","label":"Article Title"},{"value":"Cell Host & Microbe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chom.2026.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.chom.2026.02.004","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}