{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:49:57Z","timestamp":1791848997232,"version":"4.3.4"},"reference-count":117,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Host & Microbe"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.chom.2026.03.012","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T15:29:54Z","timestamp":1774970994000},"page":"905-924.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Bacteroides acidifaciens exacerbates cardiac ischemia\/reperfusion injury via the microbial-host isozyme DPP4"],"prefix":"10.1016","volume":"34","author":[{"given":"Junxia","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changyun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yupeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibao","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yahan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guisong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdan","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chom.2026.03.012_bib1","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/S0140-6736(20)30752-2","article-title":"Global burden of 87 risk factors in 204 countries and territories, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"396","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.chom.2026.03.012_bib2","first-page":"935","article-title":"Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations","volume":"38","author":"Hausenloy","year":"2017","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib3","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1056\/NEJMra071667","article-title":"Myocardial reperfusion injury","volume":"357","author":"Yellon","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chom.2026.03.012_bib4","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.cell.2020.06.030","article-title":"Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury","volume":"182","author":"Yokota","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.chom.2026.03.012_bib5","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1016\/j.jacc.2020.03.020","article-title":"Extracellular Matrix in Ischemic Heart Disease, Part 4\/4: JACC Focus Seminar","volume":"75","author":"Frangogiannis","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib6","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1093\/cvr\/cvz301","article-title":"Pathophysiology and diagnosis of coronary microvascular dysfunction in ST-elevation myocardial infarction","volume":"116","author":"Konijnenberg","year":"2020","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib7","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1016\/j.jcmg.2019.10.021","article-title":"Sudden Cardiac Death in Ischemic Heart Disease: From Imaging Arrhythmogenic Substrate to Guiding Therapies","volume":"13","author":"Gr\u00e4ni","year":"2020","journal-title":"JACC Cardiovasc. Imaging"},{"key":"10.1016\/j.chom.2026.03.012_bib8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.tem.2023.10.010","article-title":"Regulated cell death in myocardial ischemia-reperfusion injury","volume":"35","author":"Xiang","year":"2024","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.chom.2026.03.012_bib9","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1161\/CIRCULATIONAHA.121.055920","article-title":"Novel CaMKII-\u03b4 Inhibitor Hesperadin Exerts Dual Functions to Ameliorate Cardiac Ischemia\/Reperfusion Injury and Inhibit Tumor Growth","volume":"145","author":"Zhang","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib10","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1152\/physrev.00022.2018","article-title":"Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease","volume":"99","author":"Del Re","year":"2019","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.chom.2026.03.012_bib11","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1146\/annurev.physiol.010908.163111","article-title":"Cell death in the pathogenesis of heart disease: mechanisms and significance","volume":"72","author":"Whelan","year":"2010","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.chom.2026.03.012_bib12","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1517\/14728222.2013.809064","article-title":"The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias","volume":"17","author":"Westenbrink","year":"2013","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.chom.2026.03.012_bib13","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1161\/CIRCRESAHA.119.315252","article-title":"Increased Drp1 Acetylation by Lipid Overload Induces Cardiomyocyte Death and Heart Dysfunction","volume":"126","author":"Hu","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib14","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1161\/CIRCULATIONAHA.121.055841","article-title":"Elevated MCU Expression by CaMKII\u03b4B Limits Pathological Cardiac Remodeling","volume":"145","author":"Wang","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib15","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abq7839","article-title":"An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor","volume":"15","author":"Reyes Gaido","year":"2023","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.chom.2026.03.012_bib16","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1016\/j.jacc.2024.02.056","article-title":"Reperfusion Injury in Patients With Acute Myocardial Infarction: JACC Scientific Statement","volume":"83","author":"Welt","year":"2024","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib17","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1093\/eurheartj\/ehae371","article-title":"Acute myocardial infarction and ischaemic stroke: differences and similarities in reperfusion therapies-a review","volume":"45","author":"Scheldeman","year":"2024","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib18","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.1093\/eurheartj\/ehab271","volume":"42","author":"Bulluck","year":"2021","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib19","article-title":"Ischemia-reperfusion injury: molecular mechanisms and therapeutic targets","volume":"9","author":"Zhang","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.chom.2026.03.012_bib20","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1093\/cvr\/cvae185","article-title":"Heart-brain axis in health and disease: role of innate and adaptive immunity","volume":"120","author":"Simats","year":"2025","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib21","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.cmet.2025.02.009","article-title":"Remote limb ischemic conditioning alleviates steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk","volume":"37","author":"Zhao","year":"2025","journal-title":"Cell Metab."},{"key":"10.1016\/j.chom.2026.03.012_bib22","doi-asserted-by":"crossref","DOI":"10.1126\/science.adp5540","article-title":"A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite-CerS6-ceramide axis","volume":"388","author":"Zhou","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.chom.2026.03.012_bib23","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/s41586-022-05299-4","article-title":"Gut bacteria alleviate smoking-related NASH by degrading gut nicotine","volume":"610","author":"Chen","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.chom.2026.03.012_bib24","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.cmet.2019.09.016","article-title":"Adipocyte Hypoxia-Inducible Factor 2\u03b1 Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism","volume":"30","author":"Zhang","year":"2019","journal-title":"Cell Metab."},{"key":"10.1016\/j.chom.2026.03.012_bib25","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1126\/science.abn0910","article-title":"Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure","volume":"377","author":"Cao","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.chom.2026.03.012_bib26","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1093\/eurheartj\/eht271","article-title":"The heart and the gut","volume":"35","author":"Rogler","year":"2014","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib27","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1093\/eurheartj\/ehw008","article-title":"Intestinal congestion and right ventricular dysfunction: a link with appetite loss, inflammation, and cachexia in chronic heart failure","volume":"37","author":"Valentova","year":"2016","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib28","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1536\/ihj.14-255","article-title":"Assessment of transthyretin combined with mini nutritional assessment on admission provides useful prognostic information in patients with acute decompensated heart failure","volume":"56","author":"Suzuki","year":"2015","journal-title":"Int. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib29","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.1093\/eurheartj\/eht246","article-title":"Interactions of the heart and the liver","volume":"34","author":"M\u00f8ller","year":"2013","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib30","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1016\/j.jacc.2013.03.042","article-title":"Cardiohepatic interactions in heart failure: an overview and clinical implications","volume":"61","author":"Samsky","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib31","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1007\/s00134-009-1508-2","article-title":"Hypoxic hepatitis: underlying conditions and risk factors for mortality in critically ill patients","volume":"35","author":"Fuhrmann","year":"2009","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.chom.2026.03.012_bib32","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/ki.2008.107","article-title":"The risk of acute renal failure in patients with chronic kidney disease","volume":"74","author":"Hsu","year":"2008","journal-title":"Kidney Int."},{"key":"10.1016\/j.chom.2026.03.012_bib33","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1007\/s00392-016-1009-6","article-title":"Similar hemodynamic decongestion with vasodilators and inotropes: systematic review, meta-analysis, and meta-regression of 35 studies on acute heart failure","volume":"105","author":"Ishihara","year":"2016","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib34","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/ejhf.872","article-title":"Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)","volume":"19","author":"Harjola","year":"2017","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.chom.2026.03.012_bib35","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1161\/CIRCRESAHA.120.316242","article-title":"Gut Microbiota and Cardiovascular Disease","volume":"127","author":"Witkowski","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib36","article-title":"Gut microbiota and atherosclerosis","author":"Fusco","year":"2025","journal-title":"Gut"},{"key":"10.1016\/j.chom.2026.03.012_bib37","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1161\/CIRCRESAHA.124.325056","article-title":"Salt-Responsive Gut Microbiota Induces Sex-Specific Blood Pressure Changes","volume":"135","author":"Bardhan","year":"2024","journal-title":"Circ. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib38","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1161\/CIRCRESAHA.125.325516","article-title":"Gut-Heart Axis: The Role of Gut Microbiota and Metabolites in Heart Failure","volume":"136","author":"Snelson","year":"2025","journal-title":"Circ. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib39","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1161\/CIRCULATIONAHA.118.035235","article-title":"Loss of Gut Microbiota Alters Immune System Composition and Cripples Postinfarction Cardiac Repair","volume":"139","author":"Tang","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib40","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1093\/eurheartj\/ehad089","article-title":"Trimethylamine N-oxide is associated with long-term mortality risk: the multi-ethnic study of atherosclerosis","volume":"44","author":"Wang","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib41","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1056\/NEJMoa1109400","article-title":"Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk","volume":"368","author":"Tang","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chom.2026.03.012_bib42","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature09922","article-title":"Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease","volume":"472","author":"Wang","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.chom.2026.03.012_bib43","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1161\/CIRCULATIONAHA.122.060573","article-title":"Gut Microbiota-Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms","volume":"147","author":"Benson","year":"2023","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib44","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1126\/science.aav3487","article-title":"Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy","volume":"366","author":"Gil-Cruz","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.chom.2026.03.012_bib45","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.chom.2022.08.002","article-title":"Gut microbial DL-endopeptidase alleviates Crohn's disease via the NOD2 pathway","volume":"30","author":"Gao","year":"2022","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.chom.2026.03.012_bib46","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/s41586-023-06583-7","article-title":"Unraveling the functional dark matter through global metagenomics","volume":"622","author":"Pavlopoulos","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.chom.2026.03.012_bib47","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1161\/CIRCRESAHA.121.319077","article-title":"Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease","volume":"128","author":"Ridker","year":"2021","journal-title":"Circ. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2013.09.019","article-title":"The role of monocytes in angiogenesis and atherosclerosis","volume":"63","author":"Jaipersad","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib49","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1161\/CIRCRESAHA.111.300171","article-title":"Broad suppression of NADPH oxidase activity exacerbates ischemia\/reperfusion injury through inadvertent downregulation of hypoxia-inducible factor-1\u03b1 and upregulation of peroxisome proliferator-activated receptor-\u03b1","volume":"112","author":"Matsushima","year":"2013","journal-title":"Circ. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib50","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1161\/CIRCULATIONAHA.106.657486","article-title":"Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress","volume":"115","author":"Silver","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib51","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.ijbiomac.2020.01.072","article-title":"Native \u03ba-carrageenan induced-colitis is related to host intestinal microecology","volume":"147","author":"Mi","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.chom.2026.03.012_bib52","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2025.2488105","article-title":"Raffinose-metabolizing bacteria impair radiation-associated hematopoietic recovery via the bile acid\/FXR\/NF-\u03baB signaling pathway","volume":"17","author":"Jiao","year":"2025","journal-title":"Gut Microbes"},{"key":"10.1016\/j.chom.2026.03.012_bib53","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2323227","article-title":"Gut microbiota-palmitoleic acid-interleukin-5 axis orchestrates benzene-induced hematopoietic toxicity","volume":"16","author":"Zhang","year":"2024","journal-title":"Gut Microbes"},{"key":"10.1016\/j.chom.2026.03.012_bib54","doi-asserted-by":"crossref","DOI":"10.1126\/science.add5787","article-title":"Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target","volume":"381","author":"Wang","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.chom.2026.03.012_bib55","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00277-17","article-title":"Degradation of Incretins and Modulation of Blood Glucose Levels by Periodontopathic Bacterial Dipeptidyl Peptidase 4","volume":"85","author":"Ohara-Nemoto","year":"2017","journal-title":"Infect. Immun."},{"key":"10.1016\/j.chom.2026.03.012_bib56","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1038\/s41589-023-01357-8","article-title":"Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron","volume":"19","author":"Keller","year":"2023","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.chom.2026.03.012_bib57","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1001\/jama.2021.1527","article-title":"Diagnosis and Management of Stable Angina: A Review","volume":"325","author":"Joshi","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.chom.2026.03.012_bib58","doi-asserted-by":"crossref","DOI":"10.1186\/s12933-023-02118-6","article-title":"GLP-1 receptor agonists-SGLT-2 inhibitors combination therapy and cardiovascular events after acute myocardial infarction: an observational study in patients with type 2 diabetes","volume":"23","author":"Marfella","year":"2024","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.chom.2026.03.012_bib59","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1093\/cvr\/cvw216","article-title":"Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning","volume":"112","author":"Basalay","year":"2016","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib60","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cmet.2016.06.009","article-title":"The Cardiovascular Biology of Glucagon-like Peptide-1","volume":"24","author":"Drucker","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.chom.2026.03.012_bib61","article-title":"Cell-cell communication: new insights and clinical implications","volume":"9","author":"Su","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.chom.2026.03.012_bib62","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/s42255-018-0030-7","article-title":"TGF-\u03b22 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism","volume":"1","author":"Takahashi","year":"2019","journal-title":"Nat. Metab."},{"key":"10.1016\/j.chom.2026.03.012_bib63","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41579-020-0433-9","article-title":"Gut microbiota in human metabolic health and disease","volume":"19","author":"Fan","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.chom.2026.03.012_bib64","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1093\/cvr\/cvad023","article-title":"Heart-gut microbiota communication determines the severity of cardiac injury after myocardial ischaemia\/reperfusion","volume":"119","author":"Zhao","year":"2023","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib65","doi-asserted-by":"crossref","first-page":"H1210","DOI":"10.1152\/ajpheart.00346.2019","article-title":"Gut microbiota regulates cardiac ischemic tolerance and aortic stiffness in obesity","volume":"317","author":"Battson","year":"2019","journal-title":"Am. J. Physiol., Heart Circ. Physiol."},{"key":"10.1016\/j.chom.2026.03.012_bib66","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1161\/HYPERTENSIONAHA.119.13155","article-title":"Gut Microbiota Plays a Central Role to Modulate the Plasma and Fecal Metabolomes in Response to Angiotensin II","volume":"74","author":"Cheema","year":"2019","journal-title":"Hypertension"},{"key":"10.1016\/j.chom.2026.03.012_bib67","doi-asserted-by":"crossref","DOI":"10.1186\/s40168-016-0222-x","article-title":"Gut microbiota dysbiosis contributes to the development of hypertension","volume":"5","author":"Li","year":"2017","journal-title":"Microbiome"},{"key":"10.1016\/j.chom.2026.03.012_bib68","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1038\/s42255-022-00649-y","article-title":"Gut Parabacteroides merdae protects against cardiovascular damage by enhancing branched-chain amino acid catabolism","volume":"4","author":"Qiao","year":"2022","journal-title":"Nat. Metab."},{"key":"10.1016\/j.chom.2026.03.012_bib69","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/nrcardio.2016.183","article-title":"Role of gut microbiota in atherosclerosis","volume":"14","author":"Jonsson","year":"2017","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib70","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/s41575-025-01041-3","article-title":"A Consensus Statement on establishing causality, therapeutic applications and the use of preclinical models in microbiome research","volume":"22","author":"Metwaly","year":"2025","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.chom.2026.03.012_bib71","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/s41586-025-09263-w","article-title":"Imidazole propionate is a driver and therapeutic target in atherosclerosis","volume":"645","author":"Mastrangelo","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.chom.2026.03.012_bib72","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/j.cmet.2019.08.021","article-title":"Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction","volume":"30","author":"Chen","year":"2019","journal-title":"Cell Metab."},{"key":"10.1016\/j.chom.2026.03.012_bib73","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.cell.2018.09.055","article-title":"Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1","volume":"175","author":"Koh","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.chom.2026.03.012_bib74","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ads5721","article-title":"Microbial dipeptidyl peptidases of the S9B family as host-microbe isozymes","volume":"11","author":"Aljumaah","year":"2025","journal-title":"Sci. Adv."},{"key":"10.1016\/j.chom.2026.03.012_bib75","doi-asserted-by":"crossref","first-page":"E1437","DOI":"10.1073\/pnas.1717565115","article-title":"Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer","volume":"115","author":"Ross","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chom.2026.03.012_bib76","article-title":"Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta-analysis","volume":"384","author":"Yao","year":"2024","journal-title":"Br. Med. J. (Clin. Res. Ed)"},{"key":"10.1016\/j.chom.2026.03.012_bib77","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/s41569-023-00849-3","article-title":"Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action","volume":"20","author":"Ussher","year":"2023","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib78","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1161\/CIRCULATIONAHA.122.059595","article-title":"GLP-1 Receptor Agonists for the Reduction of Atherosclerotic Cardiovascular Risk in Patients With Type 2 Diabetes","volume":"146","author":"Marx","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib79","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1001\/jamainternmed.2022.0338","article-title":"Association of Glucagon-Like Peptide-1 Receptor Agonist Use With Risk of Gallbladder and Biliary Diseases: A Systematic Review and Meta-analysis of Randomized Clinical Trials","volume":"182","author":"He","year":"2022","journal-title":"JAMA Intern. Med."},{"key":"10.1016\/j.chom.2026.03.012_bib80","article-title":"Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials","volume":"372","author":"Palmer","year":"2021","journal-title":"Br. Med. J. (Clin. Res. Ed)"},{"key":"10.1016\/j.chom.2026.03.012_bib81","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S2213-8587(24)00271-7","article-title":"Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials","volume":"13","author":"Badve","year":"2025","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.chom.2026.03.012_bib82","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1056\/NEJMoa2501006","article-title":"Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes","volume":"392","author":"McGuire","year":"2025","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chom.2026.03.012_bib83","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/s41574-022-00783-3","article-title":"Beyond the pancreas: contrasting cardiometabolic actions of GIP and GLP1","volume":"19","author":"Hammoud","year":"2023","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.chom.2026.03.012_bib84","doi-asserted-by":"crossref","DOI":"10.1186\/s12933-017-0572-0","article-title":"The impact of DPP-4 inhibitors on long-term survival among diabetic patients after first acute myocardial infarction","volume":"16","author":"Wang","year":"2017","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.chom.2026.03.012_bib85","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1161\/CIRCULATIONAHA.114.010389","article-title":"Heart failure, saxagliptin, and diabetes mellitus: observations from the SAVOR-TIMI 53 randomized trial","volume":"130","author":"Scirica","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib86","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1056\/NEJMoa1501352","article-title":"Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes","volume":"373","author":"Green","year":"2015","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chom.2026.03.012_bib87","doi-asserted-by":"crossref","DOI":"10.1186\/s12933-017-0593-8","article-title":"A randomized, placebo-controlled study of the cardiovascular safety of the once-weekly DPP-4 inhibitor omarigliptin in patients with type 2 diabetes mellitus","volume":"16","author":"Gantz","year":"2017","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.chom.2026.03.012_bib88","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1056\/NEJMoa1305889","article-title":"Alogliptin after acute coronary syndrome in patients with type 2 diabetes","volume":"369","author":"White","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chom.2026.03.012_bib89","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.jcmgh.2021.12.004","article-title":"Intestinal HIF-2\u03b1 Regulates GLP-1 Secretion via Lipid Sensing in L-Cells","volume":"13","author":"Mooli","year":"2022","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.chom.2026.03.012_bib90","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1161\/CIRCRESAHA.117.309715","article-title":"Gut Microbiota in Cardiovascular Health and Disease","volume":"120","author":"Tang","year":"2017","journal-title":"Circ. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib91","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1161\/CIRCRESAHA.123.322381","article-title":"Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction","volume":"134","author":"Wang","year":"2024","journal-title":"Circ. Res."},{"key":"10.1016\/j.chom.2026.03.012_bib92","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.102649","article-title":"The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions","volume":"52","author":"Tr\u00f8seid","year":"2020","journal-title":"EBiomedicine"},{"key":"10.1016\/j.chom.2026.03.012_bib93","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.jacc.2017.12.057","article-title":"Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts","volume":"71","author":"Kummen","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib94","doi-asserted-by":"crossref","DOI":"10.1002\/mco2.70168","article-title":"Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy","volume":"6","author":"Shen","year":"2025","journal-title":"MedComm"},{"key":"10.1016\/j.chom.2026.03.012_bib95","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2020.109252","article-title":"GLP-1 receptor agonist liraglutide protects cardiomyocytes from IL-1\u03b2-induced metabolic disturbance and mitochondrial dysfunction","volume":"332","author":"Zhang","year":"2020","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.chom.2026.03.012_bib96","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1007\/s11883-022-01062-2","article-title":"GLP-1 Agonist to Treat Obesity and Prevent Cardiovascular Disease: What Have We Achieved so Far?","volume":"24","author":"Pedrosa","year":"2022","journal-title":"Curr. Atheroscler. Rep."},{"key":"10.1016\/j.chom.2026.03.012_bib97","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2022.101641","article-title":"Glucagon-like Peptide-1 receptor Tie2+ cells are essential for the cardioprotective actions of liraglutide in mice with experimental myocardial infarction","volume":"66","author":"McLean","year":"2022","journal-title":"Mol. Metab."},{"key":"10.1016\/j.chom.2026.03.012_bib98","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1161\/CIRCULATIONAHA.113.004046","article-title":"The global burden of ischemic heart disease in 1990 and 2010: the Global Burden of Disease 2010 study","volume":"129","author":"Moran","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib99","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.012188","article-title":"Prognostic Implications of Door-to-Balloon Time and Onset-to-Door Time on Mortality in Patients With ST -Segment-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention","volume":"8","author":"Park","year":"2019","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.chom.2026.03.012_bib100","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1001\/jama.2022.0358","article-title":"Diagnosis and Treatment of Acute Coronary Syndromes: A Review","volume":"327","author":"Bhatt","year":"2022","journal-title":"JAMA"},{"key":"10.1016\/j.chom.2026.03.012_bib101","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.jacc.2019.11.058","article-title":"Stent-Related Adverse Events >1 Year After Percutaneous Coronary Intervention","volume":"75","author":"Madhavan","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.chom.2026.03.012_bib102","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1016\/S0140-6736(21)02248-0","article-title":"Angiographic quantitative flow ratio-guided coronary intervention (FAVOR III China): a multicentre, randomised, sham-controlled trial","volume":"398","author":"Xu","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.chom.2026.03.012_bib103","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.jcin.2016.01.034","article-title":"Percutaneous Coronary Intervention in Native Coronary Arteries Versus Bypass Grafts in Patients With Prior Coronary Artery Bypass Graft Surgery: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program","volume":"9","author":"Brilakis","year":"2016","journal-title":"JACC, Cardiovasc. Interv."},{"key":"10.1016\/j.chom.2026.03.012_bib104","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1136\/gutjnl-2020-323071","article-title":"Gut microbiota-derived metabolites as central regulators in metabolic disorders","volume":"70","author":"Agus","year":"2021","journal-title":"Gut"},{"key":"10.1016\/j.chom.2026.03.012_bib105","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1136\/gutjnl-2024-331880","article-title":"Puerarin alleviates atherosclerosis via the inhibition of Prevotella copri and its trimethylamine production","volume":"73","year":"2024","journal-title":"Gut"},{"key":"10.1016\/j.chom.2026.03.012_bib106","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1002\/ejhf.1409","article-title":"Trimethylamine N-oxide and risk of heart failure progression: marker or mediator of disease","volume":"21","author":"Chioncel","year":"2019","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.chom.2026.03.012_bib107","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/j.cell.2015.11.055","article-title":"Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis","volume":"163","author":"Wang","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.chom.2026.03.012_bib108","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC Guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.chom.2026.03.012_bib109","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1021\/acssynbio.1c00543","article-title":"CRISPR\/Cas-Based Genome Editing for Human Gut Commensal Bacteroides Species","volume":"11","author":"Zheng","year":"2022","journal-title":"ACS Synth. Biol."},{"key":"10.1016\/j.chom.2026.03.012_bib110","article-title":"Seipin-Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia\/Reperfusion Injury","volume":"13","author":"Liu","year":"2026","journal-title":"Adv. Sci. (Weinh)"},{"key":"10.1016\/j.chom.2026.03.012_bib111","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1161\/CIRCULATIONAHA.123.068595","article-title":"Extracellular RIPK3 Acts as a Damage-Associated Molecular Pattern to Exaggerate Cardiac Ischemia\/Reperfusion Injury","volume":"150","author":"Zhang","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib112","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1021\/jm0493156","article-title":"(2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes","volume":"48","author":"Kim","year":"2005","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.chom.2026.03.012_bib113","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1161\/CIRCULATIONAHA.124.070936","article-title":"Intracellular L-PGDS-Derived 15d-PGJ2 Inhibits CaMKII Through Lipoxidation to Alleviate Cardiac Ischemia\/Reperfusion Injury","volume":"152","author":"Hu","year":"2025","journal-title":"Circulation"},{"key":"10.1016\/j.chom.2026.03.012_bib114","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1038\/s41419-021-04396-y","article-title":"Interactions between gastric microbiota and metabolites in gastric cancer","volume":"12","author":"Dai","year":"2021","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.chom.2026.03.012_bib115","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.83","article-title":"EasyAmplicon: An easy-to-use, open-source, reproducible, and community-based pipeline for amplicon data analysis in microbiome research","volume":"2","author":"Liu","year":"2023","journal-title":"Imeta"},{"key":"10.1016\/j.chom.2026.03.012_bib116","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.70001","article-title":"EasyMetagenome: A user-friendly and flexible pipeline for shotgun metagenomic analysis in microbiome research","volume":"4","author":"Bai","year":"2025","journal-title":"Imeta"},{"key":"10.1016\/j.chom.2026.03.012_bib117","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/s42255-024-01011-0","article-title":"Activation of GPR81 by lactate drives tumour-induced cachexia","volume":"6","author":"Liu","year":"2024","journal-title":"Nat. Metab."}],"container-title":["Cell Host & Microbe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312826001204?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931312826001204?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:15:54Z","timestamp":1788322554000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931312826001204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":117,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S1931312826001204"],"URL":"https:\/\/doi.org\/10.1016\/j.chom.2026.03.012","relation":{},"ISSN":["1931-3128"],"issn-type":[{"value":"1931-3128","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bacteroides acidifaciens exacerbates cardiac ischemia\/reperfusion injury via the microbial-host isozyme DPP4","name":"articletitle","label":"Article Title"},{"value":"Cell Host & Microbe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chom.2026.03.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}