{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:35:44Z","timestamp":1792632944226,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T00:00:00Z","timestamp":1705536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["chestpulmonary.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST Pulmonary"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.chpulm.2024.100037","type":"journal-article","created":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T18:00:23Z","timestamp":1706119223000},"page":"100037","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["The Diagnostic Yield of Cone Beam CT Combined With Radial-Endobronchial Ultrasound for the Diagnosis of Peripheral Pulmonary Nodules"],"prefix":"10.1016","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6678-1407","authenticated-orcid":false,"given":"Michael V.","family":"Brown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash","family":"Badiei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9510-0948","authenticated-orcid":false,"given":"Matthew","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubertus","family":"Jersmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2311-4919","authenticated-orcid":false,"given":"David","family":"Fielding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8573-3574","authenticated-orcid":false,"given":"Phan","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib1","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1148\/radiol.2017161659","article-title":"Guidelines for management of incidental pulmonary nodules detected on CT images: from the Fleischner Society 2017","volume":"284","author":"MacMahon","year":"2017","journal-title":"Radiology"},{"issue":"5","key":"10.1016\/j.chpulm.2024.100037_bib2","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1056\/NEJMoa1102873","article-title":"Reduced lung-cancer mortality with low-dose computed tomographic screening","volume":"365","author":"Aberle","year":"2011","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib3","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1378\/chest.68.1.12","article-title":"Diagnostic fiberoptic bronchoscopy: techniques and results of biopsy in 600 patients","volume":"68","author":"Zavala","year":"1975","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib4","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1378\/chest.129.1.147","article-title":"Endobronchial ultrasound-guided transbronchial lung biopsy in fluoroscopically invisible solitary pulmonary nodules: a prospective trial","volume":"129","author":"Herth","year":"2006","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.chpulm.2024.100037_bib5","doi-asserted-by":"crossref","first-page":"3551","DOI":"10.1378\/chest.128.5.3551","article-title":"Endobronchial ultrasound-driven biopsy in the diagnosis of peripheral lung lesions","volume":"128","author":"Paone","year":"2005","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.chpulm.2024.100037_bib6","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/resp.12980","article-title":"Radial endobronchial ultrasound for the diagnosis of peripheral pulmonary lesions: a systematic review and meta-analysis","volume":"22","author":"Ali","year":"2017","journal-title":"Respirology"},{"issue":"suppl 4","key":"10.1016\/j.chpulm.2024.100037_bib7","first-page":"S304","article-title":"Transthoracic needle biopsy of the lung","volume":"7","author":"DiBardino","year":"2015","journal-title":"J\u00a0Thorac Dis"},{"issue":"4","key":"10.1016\/j.chpulm.2024.100037_bib8","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1183\/09031936.00075310","article-title":"Radial probe endobronchial ultrasound for the diagnosis of peripheral lung cancer: systematic review and meta-analysis","volume":"37","author":"Steinfort","year":"2011","journal-title":"Eur Respir J"},{"issue":"4","key":"10.1016\/j.chpulm.2024.100037_bib9","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/LBR.0000000000000546","article-title":"Cone beam CT-guided bronchoscopy: Here to stay?","volume":"25","author":"Casal","year":"2018","journal-title":"J Bronchology Interv Pulmonol"},{"issue":"2","key":"10.1016\/j.chpulm.2024.100037_bib10","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1378\/chest.11-1764","article-title":"Meta-analysis of guided bronchoscopy for the evaluation of the pulmonary nodule","volume":"142","author":"Wang Memoli","year":"2012","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.chpulm.2024.100037_bib11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1159\/000355710","article-title":"Diagnostic yield and safety of electromagnetic navigation bronchoscopy for lung nodules: a systematic review and meta-analysis","volume":"87","author":"Gex","year":"2014","journal-title":"Respiration"},{"issue":"6","key":"10.1016\/j.chpulm.2024.100037_bib12","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1378\/chest.06-3016","article-title":"Electromagnetic navigation diagnostic bronchoscopy in peripheral lung lesions","volume":"131","author":"Eberhardt","year":"2007","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib13","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1186\/s12890-019-1010-8","article-title":"Robot-assisted bronchoscopy for pulmonary lesion diagnosis: results from the initial multicenter experience","volume":"19","author":"Chaddha","year":"2019","journal-title":"BMC Pulm Med"},{"issue":"2","key":"10.1016\/j.chpulm.2024.100037_bib14","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.chest.2020.08.2047","article-title":"Robotic bronchoscopy for peripheral pulmonary lesions: a multicenter pilot and feasibility study (BENEFIT)","volume":"159","author":"Chen","year":"2021","journal-title":"Chest"},{"key":"10.1016\/j.chpulm.2024.100037_bib15","doi-asserted-by":"crossref","DOI":"10.1097\/LBR.0000000000000700","article-title":"Prospective analysis of a novel endobronchial augmented fluoroscopic navigation system for diagnosis of peripheral pulmonary lesions","author":"Pritchett","year":"2021","journal-title":"J Bronchology Interv Pulmonol"},{"key":"10.1016\/j.chpulm.2024.100037_bib16","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1164\/rccm.201502-0205OC","article-title":"Ultrathin bronchoscopy with multimodal devices for peripheral pulmonary lesions. A randomized trial","volume":"(4),","author":"Oki","year":"2015","journal-title":"Am J Respir Crit Care Med, 192"},{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib17","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.pulmoe.2020.12.006","article-title":"Efficacy of radial endobronchial ultrasound (R-EBUS) guided transbronchial cryobiopsy for peripheral pulmonary lesions (PPLs): a systematic review and meta-analysis","volume":"29","author":"Sryma","year":"2023","journal-title":"Pulmonology"},{"issue":"2","key":"10.1016\/j.chpulm.2024.100037_bib18","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.athoracsur.2017.02.035","article-title":"Feasibility and safety of the transbronchial access tool for peripheral pulmonary nodule and mass","volume":"104","author":"Bowling","year":"2017","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"10.1016\/j.chpulm.2024.100037_bib19","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1183\/09031936.00111314","article-title":"Diagnostic utility and accuracy of rapid on-site evaluation of bronchoscopic brushings","volume":"45","author":"Steinfort","year":"2015","journal-title":"Eur Respir J"},{"issue":"9","key":"10.1016\/j.chpulm.2024.100037_bib20","first-page":"e778","article-title":"Cone beam CT vs. fan beam CT: a comparison of image quality and dose delivered between two differing CT imaging modalities","volume":"8","author":"Lechuga","year":"2016","journal-title":"Cureus"},{"issue":"4","key":"10.1016\/j.chpulm.2024.100037_bib21","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1097\/LBR.0000000000000536","article-title":"Cone-beam CT with augmented fluoroscopy combined with electromagnetic navigation bronchoscopy for biopsy of pulmonary nodules","volume":"25","author":"Pritchett","year":"2018","journal-title":"J Bronchology Interv Pulmonol"},{"issue":"3","key":"10.1016\/j.chpulm.2024.100037_bib22","doi-asserted-by":"crossref","first-page":"231","DOI":"10.7150\/jca.8834","article-title":"Cone beam computertomography (CBCT) in interventional chest medicine - high feasibility for endobronchial realtime navigation","volume":"5","author":"Hohenforst-Schmidt","year":"2014","journal-title":"J Cancer"},{"issue":"5","key":"10.1016\/j.chpulm.2024.100037_bib23","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/resp.14016","article-title":"Cone-beam computed tomography versus computed tomography-guided ultrathin bronchoscopic diagnosis for peripheral pulmonary lesions: a propensity score-matched analysis","volume":"26","author":"Kawakita","year":"2021","journal-title":"Respirology"},{"issue":"4","key":"10.1016\/j.chpulm.2024.100037_bib24","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1159\/000500228","article-title":"Transbronchial biopsy using an ultrathin bronchoscope guided by cone-beam computed tomography and virtual bronchoscopic navigation in the diagnosis of pulmonary nodules","volume":"98","author":"Ali","year":"2019","journal-title":"Respiration"},{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib25","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/LBR.0000000000000697","article-title":"Cone-beam CT image guidance with and without electromagnetic navigation bronchoscopy for biopsy of peripheral pulmonary lesions","volume":"28","author":"Verhoeven","year":"2021","journal-title":"J Bronchology Interv Pulmonol"},{"issue":"4","key":"10.1016\/j.chpulm.2024.100037_bib26","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1214\/aoms\/1177729756","article-title":"Transformations related to the angular and the square root","volume":"21","author":"Murray","year":"1950","journal-title":"The Annals of Mathematical Statistics"},{"issue":"3","key":"10.1016\/j.chpulm.2024.100037_bib27","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"issue":"7414","key":"10.1016\/j.chpulm.2024.100037_bib28","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"issue":"7","key":"10.1016\/j.chpulm.2024.100037_bib29","doi-asserted-by":"crossref","first-page":"4396","DOI":"10.21037\/jtd-21-518","article-title":"Multi-modal tissue sampling in cone beam CT guided navigation bronchoscopy: comparative accuracy of different sampling tools and rapid on-site evaluation of cytopathology","volume":"13","author":"Verhoeven","year":"2021","journal-title":"J\u00a0Thorac Dis"},{"issue":"6","key":"10.1016\/j.chpulm.2024.100037_bib30","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.3390\/diagnostics13061055","article-title":"Cone-beam computed-tomography-derived augmented fluoroscopy-guided biopsy for peripheral pulmonary nodules in a hybrid operating room: a case series","volume":"13","author":"Chen","year":"2023","journal-title":"Diagnostics (Basel)"},{"issue":"12","key":"10.1016\/j.chpulm.2024.100037_bib31","doi-asserted-by":"crossref","first-page":"6950","DOI":"10.21037\/jtd.2018.11.21","article-title":"Cone beam computed tomography-guided thin\/ultrathin bronchoscopy for diagnosis of peripheral lung nodules: a prospective pilot study","volume":"10","author":"Casal","year":"2018","journal-title":"J Thorac Dis"},{"issue":"5","key":"10.1016\/j.chpulm.2024.100037_bib32","doi-asserted-by":"crossref","first-page":"827","DOI":"10.3390\/diagnostics13050827","article-title":"Mobile cone-beam CT-assisted bronchoscopy for peripheral lung lesions","volume":"13","author":"Salahuddin","year":"2023","journal-title":"Diagnostics (Basel)"},{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib33","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3390\/diagnostics12010041","article-title":"Cone-beam computed tomography-derived augmented fluoroscopy improves the diagnostic yield of endobronchial ultrasound-guided transbronchial biopsy for peripheral pulmonary lesions","volume":"12","author":"Lin","year":"2022","journal-title":"Diagnostics"},{"issue":"6","key":"10.1016\/j.chpulm.2024.100037_bib34","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1159\/000515181","article-title":"Efficacy and safety of cone-beam computed tomography-derived augmented fluoroscopy combined with endobronchial ultrasound in peripheral pulmonary lesions","volume":"100","author":"Yu","year":"2021","journal-title":"Respiration"},{"key":"10.1016\/j.chpulm.2024.100037_bib35","article-title":"Diagnostic yield of cone-beam-derived augmented fluoroscopy and ultrathin bronchoscopy versus conventional navigational bronchoscopy techniques","author":"DiBardino","year":"2022","journal-title":"J Bronchology Interv Pulmonol"},{"issue":"2","key":"10.1016\/j.chpulm.2024.100037_bib36","doi-asserted-by":"crossref","first-page":"579","DOI":"10.21037\/jtd-22-1369","article-title":"Cone-beam computed tomography-guided endobronchial ultrasound using an ultrathin bronchoscope for diagnosis of peripheral pulmonary lesions: a prospective pilot study","volume":"15","author":"Kawakita","year":"2023","journal-title":"J Thorac Dis"},{"issue":"3","key":"10.1016\/j.chpulm.2024.100037_bib37","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1159\/000512802","article-title":"High accuracy of digital tomosynthesis-guided bronchoscopic biopsy confirmed by intraprocedural computed tomography","volume":"100","author":"Katsis","year":"2021","journal-title":"Respiration"},{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib38","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1159\/000510763","article-title":"Cone-beam computed tomography-guided electromagnetic navigation for peripheral lung nodules","volume":"100","author":"Kheir","year":"2021","journal-title":"Respiration"},{"issue":"4","key":"10.1016\/j.chpulm.2024.100037_bib39","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.3390\/tomography8040172","article-title":"Efficacy and safety of cone-beam CT augmented electromagnetic navigation guided bronchoscopic biopsies of indeterminate pulmonary nodules","volume":"8","author":"Podder","year":"2022","journal-title":"Tomography"},{"issue":"10","key":"10.1016\/j.chpulm.2024.100037_bib40","doi-asserted-by":"crossref","first-page":"5953","DOI":"10.21037\/jtd.2018.09.16","article-title":"Biopsy of peripheral lung nodules utilizing cone beam computer tomography with and without trans bronchial access tool: a retrospective analysis","volume":"10","author":"Sobieszczyk","year":"2018","journal-title":"J Thorac Dis"},{"issue":"4","key":"10.1016\/j.chpulm.2024.100037_bib41","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/LBR.0000000000000783","article-title":"Cone-beam CT and augmented fluoroscopy-guided navigation bronchoscopy: radiation exposure and diagnostic accuracy learning curves","volume":"28","author":"Verhoeven","year":"2021","journal-title":"J Bronchology Interv Pulmonol"},{"issue":"4","key":"10.1016\/j.chpulm.2024.100037_bib42","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1097\/LBR.0000000000000860","article-title":"Robotic-assisted bronchoscopy and cone-beam CT: a retrospective series","volume":"29","author":"Cumbo-Nacheli","year":"2022","journal-title":"J Bronchology Interv Pulmonol"},{"issue":"6","key":"10.1016\/j.chpulm.2024.100037_bib43","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s00408-022-00590-7","article-title":"Shape-sensing robotic-assisted bronchoscopy with concurrent use of radial endobronchial ultrasound and cone beam computed tomography in the evaluation of pulmonary lesions","volume":"200","author":"Styrvoky","year":"2022","journal-title":"Lung"},{"issue":"3","key":"10.1016\/j.chpulm.2024.100037_bib44","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.mayocpiqo.2022.02.004","article-title":"Combining shape-sensing robotic bronchoscopy with mobile three-dimensional imaging to verify tool-in-lesion and overcome divergence: a pilot study","volume":"6","author":"Reisenauer","year":"2022","journal-title":"Mayo Clin Proc Innov Qual Outcomes"},{"issue":"11","key":"10.1016\/j.chpulm.2024.100037_bib45","first-page":"1469","article-title":"Radiation dose to patients and clinicians during fluoroscopically-guided biopsy of peripheral pulmonary lesions","volume":"55","author":"Steinfort","year":"2010","journal-title":"Respir Care"},{"issue":"1","key":"10.1016\/j.chpulm.2024.100037_bib46","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1164\/rccm.201507-1332OC","article-title":"Diagnostic yield and complications of bronchoscopy for peripheral lung lesions. Results of the AQuIRE Registry","volume":"193","author":"Ost","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.chpulm.2024.100037_bib47","first-page":"107196","volume":"180","author":"Kops","year":"2023","journal-title":"Diagnostic yield and safety of navigation bronchoscopy: a systematic review and meta-analysis, Lung Cancer"},{"issue":"3","key":"10.1016\/j.chpulm.2024.100037_bib48","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.jtho.2018.11.013","article-title":"Electromagnetic navigation bronchoscopy for peripheral pulmonary lesions: one-year results of the prospective, multicenter NAVIGATE Study","volume":"14","author":"Folch","year":"2019","journal-title":"J Thorac Oncol"},{"issue":"8","key":"10.1016\/j.chpulm.2024.100037_bib49","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1513\/AnnalsATS.201711-856OC","article-title":"Computed tomography bronchus sign and the diagnostic yield of guided bronchoscopy for peripheral pulmonary lesions. A systematic review and meta-analysis","volume":"15","author":"Ali","year":"2018","journal-title":"Ann Am Thorac Soc"}],"container-title":["CHEST Pulmonary"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2949789224000035?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2949789224000035?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T22:31:48Z","timestamp":1722724308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2949789224000035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S2949789224000035"],"URL":"https:\/\/doi.org\/10.1016\/j.chpulm.2024.100037","relation":{},"ISSN":["2949-7892"],"issn-type":[{"value":"2949-7892","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Diagnostic Yield of Cone Beam CT Combined With Radial-Endobronchial Ultrasound for the Diagnosis of Peripheral Pulmonary Nodules","name":"articletitle","label":"Article Title"},{"value":"CHEST Pulmonary","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chpulm.2024.100037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2024 Published by Elsevier Inc. under license from the American College of Chest Physicians.","name":"copyright","label":"Copyright"}],"article-number":"100037"}}