{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:54:42Z","timestamp":1791179682698,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1016\/j.chroma.2008.01.040","type":"journal-article","created":{"date-parts":[[2008,1,22]],"date-time":"2008-01-22T12:02:20Z","timestamp":1201003340000},"page":"48-56","source":"Crossref","is-referenced-by-count":31,"title":["Development of a high performance size exclusion chromatography method to determine the stability of Human Serum Albumin in a lyophilized formulation of Interferon alfa-2b"],"prefix":"10.1016","volume":"1194","author":[{"given":"Jin","family":"Qian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinglin","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Cronin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Markovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu","family":"Rustum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2008.01.040_bib1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1126\/science.285.5424.26","volume":"285","author":"Cohen","year":"1999","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.chroma.2008.01.040_bib2","doi-asserted-by":"crossref","first-page":"839","DOI":"10.2174\/138955707781387902","volume":"7","author":"Palumbo","year":"2007","journal-title":"Mini-Rev. Med. Chem."},{"key":"10.1016\/j.chroma.2008.01.040_bib3","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1365-2710.1988.tb00185.x","volume":"13","author":"Palmer","year":"1988","journal-title":"J. Clin. Pharm. Ther."},{"key":"10.1016\/j.chroma.2008.01.040_bib4","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0169-409X(02)00027-3","volume":"54","author":"Wang","year":"2002","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.chroma.2008.01.040_bib5","doi-asserted-by":"crossref","first-page":"9906","DOI":"10.1021\/bi027434m","volume":"42","author":"Carballal","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.chroma.2008.01.040_bib6","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1211\/0022357991772574","volume":"51","author":"Oliva","year":"1999","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.chroma.2008.01.040_bib7","doi-asserted-by":"crossref","first-page":"46896","DOI":"10.1074\/jbc.M108451200","volume":"276","author":"Sengupta","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.chroma.2008.01.040_bib8","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1097\/01.CCM.0000169876.14858.91","volume":"33","author":"Bar-Or","year":"2005","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.chroma.2008.01.040_bib9","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/S0731-7085(96)01721-9","volume":"14","author":"Usami","year":"1996","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2008.01.040_bib10","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1002\/jps.20432","volume":"94","author":"Ramani","year":"2005","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.chroma.2008.01.040_bib11","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1023\/A:1015108115452","volume":"19","author":"Treuheit","year":"2002","journal-title":"Pharm. Res."},{"key":"10.1016\/j.chroma.2008.01.040_bib12","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0731-7085(03)00223-1","volume":"33","author":"Oliva","year":"2003","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2008.01.040_bib13","doi-asserted-by":"crossref","first-page":"E564","DOI":"10.1208\/aapsj080365","volume":"8","author":"Philo","year":"2006","journal-title":"AAPS J."},{"key":"10.1016\/j.chroma.2008.01.040_bib14","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/jps.20758","volume":"96","author":"Luthra","year":"2007","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.chroma.2008.01.040_bib15","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/jps.20630","volume":"96","author":"Schwegman","year":"2007","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.chroma.2008.01.040_bib16","series-title":"Practical HPLC Method Development","first-page":"523","author":"Boyes","year":"1997"},{"key":"10.1016\/j.chroma.2008.01.040_bib17","series-title":"HPLC Columns-Theory, Technology, and Practice","first-page":"140","author":"Neue","year":"1997"},{"key":"10.1016\/j.chroma.2008.01.040_bib18","doi-asserted-by":"crossref","first-page":"251R","DOI":"10.1021\/a1980015t","volume":"70","author":"Barth","year":"1998","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2008.01.040_bib19","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jbbm.2004.01.007","volume":"60","author":"Goetz","year":"2004","journal-title":"J. Biochem. Biophys. Methods"},{"key":"10.1016\/j.chroma.2008.01.040_bib20","doi-asserted-by":"crossref","first-page":"7193","DOI":"10.1016\/S0021-9258(19)68947-7","volume":"256","author":"Lee","year":"1981","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.chroma.2008.01.040_bib21","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/oxfordjournals.jbchem.a134330","volume":"94","author":"Gekko","year":"1983","journal-title":"J. Biochem."},{"key":"10.1016\/j.chroma.2008.01.040_bib22","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/j.1399-3011.2005.00290.x","volume":"66","author":"Kamberi","year":"2005","journal-title":"J. Pept. Res."},{"key":"10.1016\/j.chroma.2008.01.040_bib23","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1021\/j150512a005","volume":"58","author":"Lumry","year":"1954","journal-title":"Phys. Chem."},{"key":"10.1016\/j.chroma.2008.01.040_bib24","doi-asserted-by":"crossref","first-page":"5567","DOI":"10.1021\/bi00592a007","volume":"18","author":"Zettlmeissl","year":"1979","journal-title":"Biochemistry"},{"key":"10.1016\/j.chroma.2008.01.040_bib25","doi-asserted-by":"crossref","first-page":"E590","DOI":"10.1208\/aapsj080368","volume":"8","author":"Berkowitz","year":"2006","journal-title":"AAPS J."},{"key":"10.1016\/j.chroma.2008.01.040_bib26","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1110\/ps.04831804","volume":"13","author":"Stathopulos","year":"2004","journal-title":"Protein Sci."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967308001295?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967308001295?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T09:42:48Z","timestamp":1630575768000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967308001295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["S0021967308001295"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2008.01.040","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2008,6]]}}}