{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:54:49Z","timestamp":1791874489823,"version":"4.3.4"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.chroma.2012.12.071","type":"journal-article","created":{"date-parts":[[2013,1,9]],"date-time":"2013-01-09T13:46:45Z","timestamp":1357739205000},"page":"160-172","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":79,"special_numbering":"C","title":["Fast quantification of ten psychotropic drugs and metabolites in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry for therapeutic drug monitoring"],"prefix":"10.1016","volume":"1292","author":[{"given":"Nicolas","family":"Ansermot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlyse","family":"Brawand-Amey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Kottelat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin B.","family":"Eap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2012.12.071_bib0005","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1056\/NEJMra035458","volume":"349","author":"Freedman","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chroma.2012.12.071_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1176\/appi.ajp.161.1.1","volume":"161","author":"Lehman","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.chroma.2012.12.071_bib0015","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(08)61764-X","volume":"373","author":"Leucht","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.chroma.2012.12.071_bib0020","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1056\/NEJMoa051688","volume":"353","author":"Lieberman","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chroma.2012.12.071_bib0025","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1001\/archpsyc.63.10.1079","volume":"63","author":"Jones","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.chroma.2012.12.071_bib0030","first-page":"e06","volume":"71","author":"Gelenberg","year":"2010","journal-title":"J. Clin. Psychiatry"},{"issue":"Suppl. 4","key":"10.1016\/j.chroma.2012.12.071_bib0035","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00004850-199512004-00004","volume":"10","author":"De Boer","year":"1995","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/j.chroma.2012.12.071_bib0040","doi-asserted-by":"crossref","first-page":"516","DOI":"10.2174\/138920010791636202","volume":"11","author":"Sheehan","year":"2010","journal-title":"Curr. Drug Metab."},{"key":"10.1016\/j.chroma.2012.12.071_bib0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphar.2011.00006","volume":"2","author":"Crisafulli","year":"2011","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.chroma.2012.12.071_bib0050","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1055\/s-0031-1286287","volume":"44","author":"Hiemke","year":"2011","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.chroma.2012.12.071_bib0055","first-page":"22","volume":"38","author":"Prieto","year":"2010","journal-title":"Actas Esp. Psiquiatr."},{"key":"10.1016\/j.chroma.2012.12.071_bib0060","doi-asserted-by":"crossref","first-page":"63","DOI":"10.2165\/0003088-200948010-00005","volume":"48","author":"Lind","year":"2009","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.chroma.2012.12.071_bib0065","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.chroma.2007.10.096","volume":"1176","author":"Wille","year":"2007","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2012.12.071_bib0070","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s00414-008-0287-6","volume":"123","author":"Wille","year":"2009","journal-title":"Int. J. Legal Med."},{"key":"10.1016\/j.chroma.2012.12.071_bib0075","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0378-4347(95)00418-1","volume":"676","author":"Ascalone","year":"1996","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0080","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.jchromb.2005.11.032","volume":"830","author":"Sachse","year":"2006","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0085","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s00216-007-1195-1","volume":"388","author":"Mercolini","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.chroma.2012.12.071_bib0090","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0378-4347(95)00114-X","volume":"669","author":"Mutlib","year":"1995","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0095","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/jms.440","volume":"38","author":"Kratzsch","year":"2003","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.chroma.2012.12.071_bib0100","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.jpba.2009.07.007","volume":"50","author":"Choong","year":"2009","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2012.12.071_bib0105","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jchromb.2005.11.042","volume":"831","author":"Gschwend","year":"2006","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0110","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1002\/bmc.1076","volume":"22","author":"Nirogi","year":"2008","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.chroma.2012.12.071_bib0115","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/jat\/32.2.147","volume":"32","author":"Roman","year":"2008","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.chroma.2012.12.071_bib0120","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.jpba.2009.11.018","volume":"51","author":"Davis","year":"2010","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2012.12.071_bib0125","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1002\/bmc.1530","volume":"25","author":"Couchman","year":"2011","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.chroma.2012.12.071_bib0130","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1002\/jms.1783","volume":"45","author":"Saar","year":"2010","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.chroma.2012.12.071_bib0135","doi-asserted-by":"crossref","first-page":"583","DOI":"10.3797\/scipharm.1105-12","volume":"79","author":"Mogili","year":"2011","journal-title":"Sci. Pharm."},{"key":"10.1016\/j.chroma.2012.12.071_bib0140","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1093\/chromsci\/bms001","volume":"50","author":"Pan","year":"2012","journal-title":"J. Chromatogr. Sci."},{"key":"10.1016\/j.chroma.2012.12.071_bib0145","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/bmc.1640","volume":"26","author":"de Boer","year":"2012","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.chroma.2012.12.071_bib0150","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1002\/(SICI)1096-9888(1998100)33:10<1003::AID-JMS716>3.0.CO;2-P","volume":"33","author":"Berna","year":"1998","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.chroma.2012.12.071_bib0155","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1002\/rcm.718","volume":"16","author":"Kollroser","year":"2002","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.chroma.2012.12.071_bib0160","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1093\/jat\/33.4.212","volume":"33","author":"Nielsen","year":"2009","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.chroma.2012.12.071_bib0165","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1002\/rcm.2537","volume":"20","author":"Bhatt","year":"2006","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.chroma.2012.12.071_bib0170","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jchromb.2006.05.031","volume":"843","author":"Kirchherr","year":"2006","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0175","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1007\/s00216-009-3305-8","volume":"397","author":"Guillarme","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.chroma.2012.12.071_bib0180","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/FTD.0b013e31823bf0fd","volume":"34","author":"del Mar Ramirez Fernandez","year":"2012","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.chroma.2012.12.071_bib0185","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jchromb.2010.11.024","volume":"879","author":"Hasselstrom","year":"2011","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0190","doi-asserted-by":"crossref","first-page":"E30","DOI":"10.1208\/aapsj0901004","volume":"9","author":"Viswanathan","year":"2007","journal-title":"AAPS J."},{"key":"10.1016\/j.chroma.2012.12.071_bib0195","unstructured":"FDA, Guidance for Industry: Bioanalytical Method Validation. http:\/\/www.fda.gov\/downloads\/Drugs\/GuidanceComplianceRegulatoryInformation\/Guidances\/UCM070107.pdf 2001 (last access May 2012)."},{"key":"10.1016\/j.chroma.2012.12.071_bib0200","unstructured":"European Medicines Agency, Guideline on Bioanalytical Method Validation. http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Scientific_guideline\/2011\/08\/WC500109686.pdf 2011 (last access May 2012)."},{"key":"10.1016\/j.chroma.2012.12.071_bib0205","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.chroma.2007.03.111","volume":"1158","author":"Rozet","year":"2007","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2012.12.071_bib0210","first-page":"101","volume":"13","author":"Hubert","year":"2003","journal-title":"STP Pharma. Pract."},{"key":"10.1016\/j.chroma.2012.12.071_bib0215","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/(SICI)1097-0231(19990630)13:12<1175::AID-RCM639>3.0.CO;2-0","volume":"13","author":"Bonfiglio","year":"1999","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.chroma.2012.12.071_bib0220","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0021-9673(04)01477-3","volume":"1058","author":"Souverain","year":"2004","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2012.12.071_bib0225","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1021\/ac020361s","volume":"75","author":"Matuszewski","year":"2003","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2012.12.071_bib0230","first-page":"169","volume":"7","author":"Chapuzet","year":"1997","journal-title":"STP Pharma. Pract."},{"key":"10.1016\/j.chroma.2012.12.071_bib0235","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/j.jchromb.2011.03.049","volume":"879","author":"Choong","year":"2011","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0240","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/FTD.0b013e31821126cf","volume":"33","author":"Noetzli","year":"2011","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.chroma.2012.12.071_bib0245","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jchromb.2011.12.028","volume":"885\u2013886","author":"Ansermot","year":"2012","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0250","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S1570-0232(02)00914-5","volume":"785","author":"Polson","year":"2003","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2012.12.071_bib0255","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jpba.2012.02.008","volume":"64\u201365","author":"Noetzli","year":"2012","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2012.12.071_bib0260","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.jchromb.2006.08.045","volume":"845","author":"Marchi","year":"2007","journal-title":"J. Chromatogr. B"}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967313000356?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967313000356?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T05:38:00Z","timestamp":1758260280000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967313000356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":52,"alternative-id":["S0021967313000356"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2012.12.071","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fast quantification of ten psychotropic drugs and metabolites in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry for therapeutic drug monitoring","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2012.12.071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}