{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T01:34:13Z","timestamp":1789263253470,"version":"build-2803163510"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.chroma.2014.04.024","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T01:46:27Z","timestamp":1397612787000},"page":"128-138","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry"],"prefix":"10.1016","volume":"1345","author":[{"given":"Jannick","family":"Clemens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Longo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Seckinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Hose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter Emil","family":"Haefeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Burhenne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2014.04.024_bib0005","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/clpt.2012.240","volume":"93","author":"Dollery","year":"2013","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.chroma.2014.04.024_bib0010","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1182\/blood-2005-11-4687","volume":"108","author":"White","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.chroma.2014.04.024_bib0015","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0093-7754(01)90034-X","volume":"28","author":"Adams","year":"2001","journal-title":"Semin. Oncol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0020","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1200\/JCO.2005.11.030","volume":"23","author":"Rajkumar","year":"2005","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0025","first-page":"191","volume":"7","author":"Hideshima","year":"2003","journal-title":"Rev. Clin. Exp. Hematol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0030","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1358\/dot.2005.41.5.893706","volume":"41","author":"Montagut","year":"2005","journal-title":"Drugs Today"},{"key":"10.1016\/j.chroma.2014.04.024_bib0035","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1056\/NEJMoa030288","volume":"348","author":"Richardson","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chroma.2014.04.024_bib0040","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1056\/NEJMoa043445","volume":"354","author":"Richardson","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chroma.2014.04.024_bib0045","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1182\/blood-2011-09-379164","volume":"119","author":"Neben","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.chroma.2014.04.024_bib0050","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1200\/JCO.2011.39.6820","volume":"30","author":"Sonneveld","year":"2012","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0055","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.tvjl.2013.10.006","volume":"198","author":"Reisman","year":"2013","journal-title":"Vet. J."},{"key":"10.1016\/j.chroma.2014.04.024_bib0060","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s00280-010-1283-3","volume":"67","author":"Reece","year":"2011","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0065","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s00280-007-0424-9","volume":"60","author":"Hemeryck","year":"2007","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0070","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jchromb.2013.01.037","volume":"926","author":"Andriamanana","year":"2013","journal-title":"J. Chromatogr. B: Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.chroma.2014.04.024_bib0075","doi-asserted-by":"crossref","first-page":"e56132","DOI":"10.1371\/journal.pone.0056132","volume":"8","author":"Shabaneh","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.chroma.2014.04.024_bib0080","doi-asserted-by":"crossref","first-page":"3518","DOI":"10.1200\/JCO.2008.18.3087","volume":"27","author":"Richardson","year":"2009","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0085","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1038\/leu.2010.129","volume":"24","author":"Dispenzieri","year":"2010","journal-title":"Leukemia"},{"key":"10.1016\/j.chroma.2014.04.024_bib0090","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1007\/s00280-013-2136-7","volume":"71","author":"O\u2019Connor","year":"2013","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0095","doi-asserted-by":"crossref","first-page":"e123","DOI":"10.1111\/j.1751-553X.2009.01145.x","volume":"32","author":"L\u00fc","year":"2010","journal-title":"Int. J. Lab. Hematol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0100","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1182\/blood-2007-08-104950","volume":"112","author":"Oerlemans","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.chroma.2014.04.024_bib0105","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1016\/j.clinthera.2009.11.012","volume":"31","author":"Venkatakrishnan","year":"2009","journal-title":"Clin. Ther."},{"key":"10.1016\/j.chroma.2014.04.024_bib0110","doi-asserted-by":"crossref","first-page":"3260","DOI":"10.1182\/blood-2011-10-386789","volume":"120","author":"Kuhn","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.chroma.2014.04.024_bib0115","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1021\/ac061680c","volume":"79","author":"Brockman","year":"2007","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2014.04.024_bib0120","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1182\/blood-2012-03-415588","volume":"120","author":"Seckinger","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.chroma.2014.04.024_bib0125","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/BF02623725","volume":"25","author":"Namba","year":"1989","journal-title":"In vitro Cell. Dev. Biol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0130","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1365-2141.1990.tb04352.x","volume":"75","author":"Hamilton","year":"1990","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.chroma.2014.04.024_bib0135","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1182\/blood.V73.4.1020.1020","volume":"73","author":"Pegoraro","year":"1989","journal-title":"Blood"},{"key":"10.1016\/j.chroma.2014.04.024_bib0140","unstructured":"Bioanalytical Method Validation, Center of Drug Evaluation and Research, Food and Drug Association (FDA), c2001 [cited 2014 Jan 22]. Available from: http:\/\/www.fda.gov\/downloads\/Drugs\/Guidances\/ucm070107.pdf."},{"key":"10.1016\/j.chroma.2014.04.024_bib0145","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1021\/ac020361s","volume":"75","author":"Matuszewski","year":"2003","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2014.04.024_bib0150","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1345\/aph.1E620","volume":"39","author":"Andr\u00e9","year":"2005","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.chroma.2014.04.024_bib0155","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1177\/1078155210386268","volume":"17","author":"Vanderloo","year":"2011","journal-title":"J. Oncol. Pharm. Pract."},{"key":"10.1016\/j.chroma.2014.04.024_bib0160","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jpba.2004.03.005","volume":"35","author":"Souverain","year":"2004","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2014.04.024_bib0165","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/BF02467489","volume":"47","author":"Dawidowicz","year":"1998","journal-title":"Chromatographia"},{"key":"10.1016\/j.chroma.2014.04.024_bib0170","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0731-7085(02)00002-X","volume":"28","author":"Naidong","year":"2002","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2014.04.024_bib0175","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.jpba.2004.02.028","volume":"35","author":"James","year":"2004","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2014.04.024_bib0180","first-page":"149","volume":"59","author":"James","year":"2004","journal-title":"Chromatographia"},{"key":"10.1016\/j.chroma.2014.04.024_bib0185","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/rcm.1276","volume":"18","author":"Mallet","year":"2004","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.chroma.2014.04.024_bib0190","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S1570-0232(02)00914-5","volume":"785","author":"Polson","year":"2003","journal-title":"J. Chromatogr. B: Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.chroma.2014.04.024_bib0195","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1124\/jpet.111.187542","volume":"341","author":"Verbrugge","year":"2012","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.chroma.2014.04.024_bib0200","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.bbrc.2007.07.049","volume":"361","author":"Rumpold","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967314005767?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967314005767?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T05:41:55Z","timestamp":1758260515000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967314005767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":40,"alternative-id":["S0021967314005767"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2014.04.024","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2014.04.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}