{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:22:26Z","timestamp":1788456146071,"version":"build-2803163510"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003030","name":"Ag\u00e8ncia de Gesti\u00f3 d&apos;Ajuts Universitaris i de Recerca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["CTM2013-48548-C2"],"award-info":[{"award-number":["CTM2013-48548-C2"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["ICRA-ENV 2017 SGR 1124"],"award-info":[{"award-number":["ICRA-ENV 2017 SGR 1124"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["SGR 1404"],"award-info":[{"award-number":["SGR 1404"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.chroma.2018.06.027","type":"journal-article","created":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T11:34:46Z","timestamp":1528716886000},"page":"57-68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["An automated on-line turbulent flow liquid-chromatography technology coupled to a high resolution mass spectrometer LTQ-Orbitrap for suspect screening of antibiotic transformation products during microalgae wastewater treatment"],"prefix":"10.1016","volume":"1568","author":[{"given":"Adri\u00e1n","family":"Ja\u00e9n-Gil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Hom-Diaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6065-2129","authenticated-orcid":false,"given":"Marta","family":"Llorca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Vicent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paqui","family":"Bl\u00e1nquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dami\u00e0","family":"Barcel\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2962-8144","authenticated-orcid":false,"given":"Sara","family":"Rodr\u00edguez-Mozaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2018.06.027_bib0005","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1007\/s00216-014-7672-4","article-title":"Suspect screening and target quantification of multi-class pharmaceuticals in surface water based on large-volume injection liquid chromatography and time-of-flight mass spectrometry","volume":"406","author":"Vergeynst","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.chroma.2018.06.027_bib0010","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.biortech.2016.01.038","article-title":"Biodegradation of carbamazepine using freshwater microalgae Chlamydomonas mexicana and Scenedesmus obliquus and the determination of its metabolic fate","volume":"205","author":"Xiong","year":"2016","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0015","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.copbio.2008.05.006","article-title":"Antibiotics and antibiotic resistance in water environments","volume":"19","author":"Baquero","year":"2008","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0020","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/1741-7007-8-123","article-title":"Q&A: antibiotic resistance: where does it come from and what can we do about it?","volume":"8","author":"Wright","year":"2010","journal-title":"BMC Biol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0025","series-title":"Safe Management of Wastes from Health-Care Activities","author":"Chartier","year":"2014"},{"key":"10.1016\/j.chroma.2018.06.027_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jhazmat.2012.05.040","article-title":"Occurrence of organic microcontaminants in the wastewater treatment process. A mini review","volume":"239\u2013240","author":"Ratola","year":"2012","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2018.06.027_bib0035","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.scitotenv.2012.04.028","article-title":"Occurrence of pharmaceutical compounds in urban wastewater: removal, mass load and environmental risk after a secondary treatment\u2014a review","volume":"429","author":"Verlicchi","year":"2012","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chroma.2018.06.027_bib0040","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.watres.2017.01.005","article-title":"From the conventional biological wastewater treatment to hybrid processes, the evaluation of organic micropollutant removal: a review","volume":"111","author":"Grandcl\u00e9ment","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.chroma.2018.06.027_bib0045","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jhazmat.2015.08.050","article-title":"Assessment of the mechanisms involved in the removal of emerging contaminants by microalgae from wastewater: a laboratory scale study","volume":"301","author":"Matamoros","year":"2016","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2018.06.027_bib0050","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s11157-016-9397-7","article-title":"Efficacy of microalgae for industrial wastewater treatment: a review on operating conditions, treatment efficiency and biomass productivity","volume":"15","author":"Umamaheswari","year":"2016","journal-title":"Rev. Environ. Sci. Biotechnol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0055","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.jhazmat.2016.04.073","article-title":"Ciprofloxacin toxicity and its co-metabolic removal by a freshwater microalga Chlamydomonas mexicana","volume":"323","author":"Xiong","year":"2017","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2018.06.027_bib0060","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.cej.2016.12.110","article-title":"A new disposal method for systematically processing of ceftazidime: the intimate coupling UV\/algae-algae treatment","volume":"314","author":"Liu","year":"2017","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.chroma.2018.06.027_bib0065","doi-asserted-by":"crossref","first-page":"59953","DOI":"10.1039\/C5RA10806C","article-title":"Understanding the algal contribution in combined UV-algae treatment to remove antibiotic cefradine","volume":"5","author":"Du","year":"2015","journal-title":"RSC Adv."},{"key":"10.1016\/j.chroma.2018.06.027_bib0070","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jhazmat.2016.03.085","article-title":"Emerging contaminant degradation and removal in algal wastewater treatment ponds: identifying the research gaps","volume":"313","author":"Norvill","year":"2016","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2018.06.027_bib0075","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jenvman.2015.03.003","article-title":"Microalgae cultivation on wastewater digestate: \u03b2-estradiol and 17\u03b1-ethynylestradiol degradation and transformation products identification","volume":"155","author":"Hom-Diaz","year":"2015","journal-title":"J. Environ. Manage."},{"key":"10.1016\/j.chroma.2018.06.027_bib0080","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.chemosphere.2013.10.013","article-title":"Biotransformation of progesterone and norgestrel by two freshwater microalgae (Scenedesmus obliquus and Chlorella pyrenoidosa): transformation kinetics and products identification","volume":"95","author":"Peng","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.chroma.2018.06.027_bib0085","doi-asserted-by":"crossref","first-page":"12270","DOI":"10.1007\/s11356-014-3157-4","article-title":"Toxicity of atrazine and its bioaccumulation and biodegradation in a green microalga, Chlamydomonas mexicana","author":"Kabra","year":"2014","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.chroma.2018.06.027_bib0090","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1039\/C7EM00100B","article-title":"Exploring micropollutant biotransformation in three freshwater phytoplankton species","volume":"19","author":"Stravs","year":"2017","journal-title":"Environ. Sci. Process. Impacts"},{"key":"10.1016\/j.chroma.2018.06.027_bib0095","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.1021\/es1030799","article-title":"Recent advances in environmental risk assessment of transformation products","volume":"45","author":"Escher","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0100","doi-asserted-by":"crossref","first-page":"6237","DOI":"10.1007\/s00216-015-8681-7","article-title":"Non-target screening with high-resolution mass spectrometry: critical review using a collaborative trial on water analysis","volume":"407","author":"Schymanski","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.chroma.2018.06.027_bib0105","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.trac.2007.10.005","article-title":"Mass spectrometry for identifying pharmaceutical biotransformation products in the environment","volume":"26","author":"Kosjek","year":"2007","journal-title":"TrAC\u2014Trends Anal. Chem."},{"key":"10.1016\/j.chroma.2018.06.027_bib0110","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1039\/C1AY05385J","article-title":"Target and non-target screening strategies for organic contaminants, residues and illicit substances in food, environmental and human biological samples by UHPLC-QTOF-MS","volume":"4","author":"D\u00edaz","year":"2012","journal-title":"Anal. Methods"},{"key":"10.1016\/j.chroma.2018.06.027_bib0115","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1021\/es5002105","article-title":"Identifying small molecules via high resolution mass spectrometry: communicating confidence","volume":"48","author":"Schymanski","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0120","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1021\/es4044374","article-title":"Strategies to characterize polar organic contamination in wastewater: exploring the capability of high resolution mass spectrometry","volume":"48","author":"Schymanski","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0125","series-title":"State-of-the-Art of Screening Methods for the Rapid Identification of Chemicals in Drinking Water ERNCIP Thematic Area Chemical & Biological Risks in the Water Sector","author":"Task","year":"2013"},{"key":"10.1016\/j.chroma.2018.06.027_bib0130","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.envpol.2013.07.048","article-title":"Identification of novel micropollutants in wastewater by a combination of suspect and nontarget screening","volume":"184","author":"Hug","year":"2014","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chroma.2018.06.027_bib0135","doi-asserted-by":"crossref","first-page":"6289","DOI":"10.1007\/s00216-015-8852-6","article-title":"Advances in liquid chromatography-high-resolution mass spectrometry for quantitative and qualitative environmental analysis","volume":"407","author":"Ace\u00f1a","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.chroma.2018.06.027_bib0140","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.chroma.2016.03.063","article-title":"Liquid chromatography coupled to tandem and high resolution mass spectrometry for the characterisation of ofloxacin transformation products after titanium dioxide photocatalysis","volume":"1443","author":"Jimenez-Villarin","year":"2016","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.06.027_bib0145","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1021\/acs.estlett.6b00455","article-title":"Integrated framework for identifying toxic transformation products in complex environmental mixtures","volume":"4","author":"Chibwe","year":"2017","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.chroma.2018.06.027_bib0150","doi-asserted-by":"crossref","first-page":"7039","DOI":"10.1021\/es901979h","article-title":"Identification of transformation products of organic contaminants in natural waters by computer-aided prediction and high-resolution mass spectrometry","volume":"43","author":"Kern","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0155","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.chemosphere.2016.08.039","article-title":"Suspect screening of OH-PAHs and non-target screening of other organic compounds in wood smoke particles using HR-orbitrap-MS","volume":"163","author":"Avagyan","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.chroma.2018.06.027_bib0160","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.chemosphere.2014.05.072","article-title":"Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap","volume":"119","author":"Llorca","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.chroma.2018.06.027_bib0165","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.chroma.2012.06.078","article-title":"Direct analysis of pharmaceuticals, their metabolites and transformation products in environmental waters using on-line TurboFlowTM chromatography-liquid chromatography-tandem mass spectrometry","volume":"1252","author":"L\u00f3pez-Serna","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.06.027_bib0170","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.chroma.2012.07.024","article-title":"Achievements and future trends in the analysis of emerging organic contaminants in environmental samples by mass spectrometry and bioanalytical techniques","volume":"1259","author":"Farr\u00e9","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.06.027_bib0175","unstructured":"A. Hom-Diaz, Degradation of pharmaceutical compounds by microalgae: photobioreactor wastewater treatment, biomass harvesting and methanization, Universitat Aut\u00f2noma de Barcelona, 2016. http:\/\/www.tdx.cat\/handle\/10803\/390962 (accessed June 12, 2018)."},{"key":"10.1016\/j.chroma.2018.06.027_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.scitotenv.2017.02.224","article-title":"Performance of a microalgal photobioreactor treating toilet wastewater: pharmaceutically active compound removal and biomass harvesting","volume":"592","author":"Hom-Diaz","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chroma.2018.06.027_bib0185","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.watres.2018.02.060","article-title":"Effect of cultivation conditions on \u03b2-estradiol removal at laboratory and pilot-plant photobioreactor by an algal-bacteria consortium","volume":"137","author":"Parlad\u00e9","year":"2018","journal-title":"Water Res."},{"key":"10.1016\/j.chroma.2018.06.027_bib0190","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.chroma.2012.05.084","article-title":"Fast and comprehensive multi-residue analysis of a broad range of human and veterinary pharmaceuticals and some of their metabolites in surface and treated waters by ultra-high-performance liquid chromatography coupled to quadrupole-linear ion trap tandem","volume":"1248","author":"Gros","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.06.027_bib0195","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.trac.2014.11.009","article-title":"Targeted and non-targeted liquid chromatography-mass spectrometric workflows for identification of transformation products of emerging pollutants in the aquatic environment","volume":"66","author":"Bletsou","year":"2015","journal-title":"TrAC\u2014Trends Anal. Chem."},{"key":"10.1016\/j.chroma.2018.06.027_bib0200","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.chroma.2015.10.077","article-title":"Suspect screening of emerging pollutants and their major transformation products in wastewaters treated with fungi by liquid chromatography coupled to a high resolution mass spectrometry","volume":"1439","author":"Llorca","year":"2016","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.06.027_bib0205","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1002\/rcm.7405","article-title":"Development of a suspect and non-target screening approach to detect veterinary antibiotic residues in a complex biological matrix using liquid chromatography\/high-resolution mass spectrometry","volume":"29","author":"Solliec","year":"2015","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.chroma.2018.06.027_bib0210","doi-asserted-by":"crossref","first-page":"8002","DOI":"10.1016\/j.chroma.2011.09.003","article-title":"Use of an accurate-mass database for the systematic identification of transformation products of organic contaminants in wastewater effluents","volume":"1218","author":"del Mar G\u00f3mez-Ramos","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.06.027_bib0215","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1248\/cpb.40.725","article-title":"Physicochemical properties and stability in the acidic solution of a new macrolide antibiotic, clarithromycin, in comparison with erythromycin","volume":"40","author":"Nakagawa","year":"1992","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.chroma.2018.06.027_bib0220","doi-asserted-by":"crossref","first-page":"10098","DOI":"10.1021\/jp073030y","article-title":"Mechanism for the degradation of erythromycin A and erythromycin A 2\u2019-ethyl succinate in acidic aqueous solution","volume":"111","author":"Hassanzadeh","year":"2007","journal-title":"J. Phys. Chem. A"},{"key":"10.1016\/j.chroma.2018.06.027_bib0225","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.scitotenv.2013.09.057","article-title":"Photodegradation of antibiotics under simulated solar radiation: implications for their environmental fate","volume":"470\u2013471","author":"Batchu","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chroma.2018.06.027_bib0230","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.chemosphere.2010.12.025","article-title":"Photodegradation of azithromycin in various aqueous systems under simulated and natural solar radiation: kinetics and identification of photoproducts","volume":"83","author":"Tong","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.chroma.2018.06.027_bib0235","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1574-6968.2004.tb09529.x","article-title":"Mineralization of erythromycin A in aquaculture sediments","volume":"234","author":"Kim","year":"2004","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.chroma.2018.06.027_bib0240","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1021\/bi201790u","article-title":"Mechanism and diversity of the erythromycin esterase family of enzymes","volume":"51","author":"Morar","year":"2012","journal-title":"Biochemistry"},{"key":"10.1016\/j.chroma.2018.06.027_bib0245","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.7164\/antibiotics.37.1692","article-title":"Enzymic hydrolysis of erythomycin by a strain of escherichia coli","author":"Barth\u00e9l\u00e9my","year":"1984","journal-title":"J. Antibiot. (Tokyo)"},{"key":"10.1016\/j.chroma.2018.06.027_bib0250","doi-asserted-by":"crossref","first-page":"217","DOI":"10.2174\/1568005043340696","article-title":"Inactivation of macrolides by producers and pathogens","volume":"4","author":"Matsuoka","year":"2004","journal-title":"Curr. Drug Targets Infect. Disord."},{"key":"10.1016\/j.chroma.2018.06.027_bib0255","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jes.2016.08.004","article-title":"Transformation of erythromycin during secondary effluent soil aquifer recharging: removal contribution and degradation path","volume":"51","author":"Wei","year":"2017","journal-title":"J. Environ. Sci. (China)"},{"key":"10.1016\/j.chroma.2018.06.027_bib0260","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/jac\/25.suppl_A.39","article-title":"Comparison of the acid stability of azithromycin and erythromycin A","volume":"25","author":"Fiese","year":"1990","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.chroma.2018.06.027_bib0265","doi-asserted-by":"crossref","first-page":"5575","DOI":"10.1016\/j.watres.2012.07.043","article-title":"Photodegradation of fluoroquinolones in surface water and antimicrobial activity of the photoproducts","volume":"46","author":"Sturini","year":"2012","journal-title":"Water Res."},{"key":"10.1016\/j.chroma.2018.06.027_bib0270","doi-asserted-by":"crossref","first-page":"2400","DOI":"10.1021\/es902852v","article-title":"Aquatic photochemistry of fluoroquinolone antibiotics: kinetics, pathways, and multivariate effects of main water constituents","volume":"44","author":"Linke","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2018.06.027_bib0275","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.scitotenv.2013.04.054","article-title":"Light-induced catalytic transformation of ofloxacin by solar Fenton in various water matrices at a pilot plant: mineralization and characterization of major intermediate products","volume":"461\u2013462","author":"Michael","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chroma.2018.06.027_bib0280","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.chroma.2014.01.069","article-title":"Degradation of fluoroquinolone antibiotics and identification of metabolites\/transformation products by liquid chromatography-tandem mass spectrometry","volume":"1333","author":"Maia","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.06.027_bib0285","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.chemosphere.2014.02.013","article-title":"Characterization of photo-transformation products of the antibiotic drug ciprofloxacin with liquid chromatography-tandem mass spectrometry in combination with accurate mass determination using an LTQ-orbitrap","volume":"115","author":"Haddad","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.chroma.2018.06.027_bib0290","doi-asserted-by":"crossref","first-page":"613","DOI":"10.4065\/74.6.613","article-title":"The macrolides: erythromycin, clarithromycin, and azithromycin","volume":"74","author":"Alvarez-Elcoro","year":"1999","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.chroma.2018.06.027_bib0295","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1046\/j.1365-2125.2000.00261.x","article-title":"Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin","volume":"50","author":"Westphal","year":"2000","journal-title":"Br. J. Clin. Pharmacol."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967318307702?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967318307702?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T05:47:34Z","timestamp":1758260854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967318307702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":59,"alternative-id":["S0021967318307702"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2018.06.027","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An automated on-line turbulent flow liquid-chromatography technology coupled to a high resolution mass spectrometer LTQ-Orbitrap for suspect screening of antibiotic transformation products during microalgae wastewater treatment","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2018.06.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}