{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:45:03Z","timestamp":1790282703464,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51675420"],"award-info":[{"award-number":["51675420"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"111 Program","award":["B12016"],"award-info":[{"award-number":["B12016"]}]},{"name":"National Key Research & Development (R&D) Program of China","award":["2016YFB0501604-02"],"award-info":[{"award-number":["2016YFB0501604-02"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.chroma.2018.08.058","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T17:54:36Z","timestamp":1535738076000},"page":"27-36","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Micro-fabricated packed metal gas preconcentrator for enhanced monitoring of ultralow concentration of isoprene"],"prefix":"10.1016","volume":"1572","author":[{"given":"Baoqing","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hairong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tinghan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guishan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiuhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2018.08.058_bib0005","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.cgh.2011.03.020","article-title":"Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008","volume":"9","author":"Younossi","year":"2011","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.chroma.2018.08.058_bib0010","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/ajg.2011.314","article-title":"Hospital readmissions among patients with decompensated cirrhosis","volume":"107","author":"Volk","year":"2012","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.chroma.2018.08.058_bib0015","doi-asserted-by":"crossref","first-page":"e112","DOI":"10.1038\/ctg.2015.40","article-title":"Isoprene in the exhaled breath is a novel biomarker for advanced fibrosis in patients with chronic liver disease: a pilot study","volume":"6","author":"Alkhouri","year":"2015","journal-title":"Clin. Transl. Gastroenterol."},{"key":"10.1016\/j.chroma.2018.08.058_bib0020","doi-asserted-by":"crossref","first-page":"16820","DOI":"10.3748\/wjg.v20.i45.16820","article-title":"Non-invasive diagnosis of advanced fibrosis and cirrhosis","volume":"20","author":"Sharma","year":"2014","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.chroma.2018.08.058_bib0025","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/hep.22742","article-title":"Liver biopsy","volume":"49","author":"Rockey","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.chroma.2018.08.058_bib0030","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/bmc.835","article-title":"Human exhaled air analytics: biomarkers of diseases","volume":"21","author":"Buszewski","year":"2007","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.chroma.2018.08.058_bib0035","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.sna.2011.01.019","article-title":"A microfluidic preconcentrator for enhanced monitoring of ethylene gas","volume":"167","author":"Dow","year":"2011","journal-title":"Sens. Actuators A Phys."},{"key":"10.1016\/j.chroma.2018.08.058_bib0040","series-title":"Design and Analysis of a Preconcentrator for the ChemLab, Office of Scientific & Technical Information Technical Reports","author":"Wong","year":"2000"},{"key":"10.1016\/j.chroma.2018.08.058_bib0045","first-page":"262","article-title":"Microfabricated silicon gas chromatographic microchannels: fabrication and performance","volume":"3511","author":"Fryemason","year":"1998","journal-title":"Proc. SPIE \u2013 Int. Soc. Opt. Eng."},{"key":"10.1016\/j.chroma.2018.08.058_bib0050","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.snb.2008.01.019","article-title":"Sub-ppm gas sensor detection via spiral \u03bc-preconcentrator","volume":"132","author":"Gr\u00e0cia","year":"2008","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.chroma.2018.08.058_bib0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9673(03)00560-0","article-title":"A microfabricated microconcentrator for sensors and gas chromatography","volume":"996","author":"Kim","year":"2003","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.08.058_bib0060","article-title":"Thin film preconcentrator array, in","author":"Krishnaswamy","year":"1996","journal-title":"US"},{"key":"10.1016\/j.chroma.2018.08.058_bib0065","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1039\/b111689d","article-title":"Multi-adsorbent preconcentration\/focusing module for portable-GC\/microsensor-array analysis of complex vapor mixtures","volume":"127","author":"Lu","year":"2002","journal-title":"Analyst"},{"key":"10.1016\/j.chroma.2018.08.058_bib0070","series-title":"Principles, Techniques and Applications","author":"Brenner","year":"1962"},{"key":"10.1016\/j.chroma.2018.08.058_bib0075","series-title":"Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International","first-page":"249","article-title":"Microfluidic channels in porous silicon filled with a carbon absorbent for GAS preconcentration","author":"Camara","year":"2007"},{"key":"10.1016\/j.chroma.2018.08.058_bib0080","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.chroma.2015.12.001","article-title":"Micro-fabricated packed gas chromatography column based on laser etching technology","volume":"1429","author":"Sun","year":"2015","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.08.058_bib0085","first-page":"15039","volume":"1","author":"Akbar","year":"2015"},{"key":"10.1016\/j.chroma.2018.08.058_bib0090","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.snb.2014.02.001","article-title":"High sensitive and selective ethylene measurement by using a large-capacity-on-chip preconcentrator device","volume":"197","author":"Janssen","year":"2014","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.chroma.2018.08.058_bib0095","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.snb.2011.12.110","article-title":"Application of a miniaturised packed gas chromatography column and a SnO 2 gas detector for analysis of low molecular weight hydrocarbons with focus on ethylene detection","volume":"180","author":"Sklorz","year":"2013","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.chroma.2018.08.058_bib0100","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.chroma.2013.01.009","article-title":"Hybrid preconcentrator\/focuser module for determinations of explosive marker compounds with a micro-scale gas chromatograph","volume":"1279","author":"Serrano","year":"2013","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2018.08.058_bib0105","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1016\/j.microrel.2012.05.012","article-title":"A gas micropreconcentrator for low level acetone measurements","volume":"52","author":"Rydosz","year":"2012","journal-title":"Microelectron. Reliab."},{"key":"10.1016\/j.chroma.2018.08.058_bib0110","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.aca.2010.12.039","article-title":"A micro gas preconcentrator with improved performance for pollution monitoring and explosives detection","volume":"688","author":"Camara","year":"2011","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.chroma.2018.08.058_bib0115","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.snb.2010.09.029","article-title":"A micromachined preconcentrator for ethylene monitoring system","volume":"151","author":"Dow","year":"2010","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.chroma.2018.08.058_bib0120","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.snb.2010.05.054","article-title":"Micro gas preconcentrator in porous silicon filled with a carbon absorbent","volume":"148","author":"Camara","year":"2010","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.chroma.2018.08.058_bib0125","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.snb.2008.01.063","article-title":"MEMS-based multi-inlet\/outlet preconcentrator coated by inkjet printing of polymer adsorbents","volume":"133","author":"Alfeeli","year":"2008","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.chroma.2018.08.058_bib0130","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.snb.2007.07.032","article-title":"Improvement of the gas sensor response via silicon \u03bc-preconcentrator","volume":"127","author":"Ivanov","year":"2007","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.chroma.2018.08.058_bib0135","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1109\/JMEMS.2005.844842","article-title":"Multiple-stage microfabricated preconcentrator-focuser for micro gas chromatography system","volume":"14","author":"Tian","year":"2005","journal-title":"J. Microelectromechanical Syst."},{"key":"10.1016\/j.chroma.2018.08.058_bib0140","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1541\/ieejsmas.130.207","article-title":"Micro gas preconcentrator made of a film of single-walled carbon nanotubes","volume":"130","author":"Takada","year":"2010","journal-title":"Ieej Trans. Sens. Micromach."},{"key":"10.1016\/j.chroma.2018.08.058_bib0145","series-title":"Recent Advancements in the Gas-Phase MicroChemLab","author":"Lewis","year":"2006"},{"key":"10.1016\/j.chroma.2018.08.058_bib0150","series-title":"Monolithically-integrated MicroChemLab for Gas-phase Chemical Analysis","author":"Kottenstette","year":"2003"},{"key":"10.1016\/j.chroma.2018.08.058_bib0155","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1039\/b003385p","article-title":"Performance evaluation of a sorbent tube sampling method using short path thermal desorption for volatile organic compounds","volume":"2","author":"Peng","year":"2000","journal-title":"J. Environ. Monit. Jem"},{"key":"10.1016\/j.chroma.2018.08.058_bib0160","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.jpba.2013.09.028","article-title":"Double-bed-type extraction needle packed with activated-carbon-based sorbents for very volatile organic compounds","volume":"88","author":"Ueta","year":"2014","journal-title":"J. Pharm. Biomed. Anal."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967318310781?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967318310781?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T12:50:23Z","timestamp":1536670223000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967318310781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":32,"alternative-id":["S0021967318310781"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2018.08.058","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Micro-fabricated packed metal gas preconcentrator for enhanced monitoring of ultralow concentration of isoprene","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2018.08.058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}