{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T09:56:21Z","timestamp":1768902981995,"version":"3.49.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100013007","name":"Universit\u00e0 Ca&apos; Foscari Venezia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013007","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009120","name":"Centre International de Recherche aux Fronti\u00e8res de la Chimie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009120","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.chroma.2020.461303","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T11:15:30Z","timestamp":1591182930000},"page":"461303","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Comparative enantioseparation of chiral 4,4\u2019-bipyridine derivatives on coated and immobilized amylose-based chiral stationary phases"],"prefix":"10.1016","volume":"1625","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3489-3428","authenticated-orcid":false,"given":"Paola","family":"Peluso","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Sechi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8258-7332","authenticated-orcid":false,"given":"Alessandro","family":"Dess\u00ec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Dallocchio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Cossu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Aubert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3924-530X","authenticated-orcid":false,"given":"Patrick","family":"Pale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8996-7880","authenticated-orcid":false,"given":"Victor","family":"Mamane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bezhan","family":"Chankvetadze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2020.461303_bib0001","first-page":"93","article-title":"Polysaccharide-based chiral stationary phases for enantioseparations by high-performance liquid chromatography: an overview","volume":"1985","author":"Chankvetadze","year":"2019"},{"key":"10.1016\/j.chroma.2020.461303_bib0002","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1021\/acs.chemrev.5b00317","article-title":"Efficient separation of enantiomers using stereoregular chiral polymers","volume":"116","author":"Shen","year":"2016","journal-title":"Chem. Rev."},{"key":"10.1016\/j.chroma.2020.461303_bib0003","doi-asserted-by":"crossref","first-page":"430","DOI":"10.2533\/chimia.2017.430","article-title":"Polysaccharide derivatives as unique chiral selectors for enantioselective chromatography","volume":"71","author":"Francotte","year":"2017","journal-title":"Chimia"},{"key":"10.1016\/j.chroma.2020.461303_bib0004","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.chroma.2009.10.022","article-title":"Chiral recognition by enantioselective liquid chromatography: mechanisms and modern chiral stationary phases","volume":"1217","author":"L\u00e4mmerhofer","year":"2010","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2019.115639","article-title":"Chiral recognition in separation sciences. Part I: polysaccharide and cyclodextrin selectors","volume":"120","author":"Scriba","year":"2019","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.chroma.2020.461303_bib0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2019.460788","article-title":"Halogen bond in separation science: a critical analysis across experimental and theoretical results","volume":"1616","author":"Peluso","year":"2020","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0007","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.chroma.2019.05.026","article-title":"Chromatographic and thermodynamic comparison of amylose tris(3-chloro-5-methylphenylcarbamate) coated or covalently immobilized on silica in high-performance liquid chromatographic separation of the enantiomers of select chiral weak acids","volume":"1602","author":"Maisuradze","year":"2019","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0008","series-title":"Chiral Separation Techniques - a Practical Approach","first-page":"99","article-title":"Analytical and preparative potential of immobilized polysaccharide-derived chiral stationary phases","author":"Zhang","year":"2006"},{"key":"10.1016\/j.chroma.2020.461303_bib0009","doi-asserted-by":"crossref","first-page":"8394","DOI":"10.1016\/j.chroma.2011.09.052","article-title":"Application of 3 \u03bcm particle-based amylose-derived chiral stationary phases for the enantioseparation of potential histone deacetylase inhibitors","volume":"1218","author":"Ferretti","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0010","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s10337-018-3493-5","article-title":"Comparative enantiomer-resolving ability of coated and covalently immobilized versions of two polysaccharide-based chiral selectors in high-performance liquid chromatography","volume":"81","author":"Beridze","year":"2018","journal-title":"Chromatographia"},{"key":"10.1016\/j.chroma.2020.461303_bib0011","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.chroma.2019.04.024","article-title":"The effect of temperature on the separation of enantiomers with coated and covalently immobilized polysaccharide-based chiral stationary phases","volume":"1599","author":"Matarashvili","year":"2019","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2019.115709","article-title":"Recent trends in preparation, investigation and application of polysaccharide-based chiral stationary phases for separation of enantiomers in high-performance liquid chromatography","volume":"122","author":"Chankvetadze","year":"2020","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.chroma.2020.461303_bib0013","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.chroma.2007.12.066","article-title":"Molecular dynamic theories in chromatography","volume":"1184","author":"Felinger","year":"2008","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0014","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.chroma.2009.12.044","article-title":"Characterization of adsorption processes in analytical liquid\u2013solid chromatography","volume":"1217","author":"Fornstedt","year":"2010","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0015","first-page":"871","article-title":"Density functional theory","volume":"Ch. 15","author":"Band","year":"2013"},{"key":"10.1016\/j.chroma.2020.461303_bib0016","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.3390\/molecules25092213","article-title":"Rational design, synthesis, characterization and evaluation of iodinated 4,4\u2019-bipyridines as new transthyretin fibrillogenesis inhibitors","volume":"25","author":"Dess\u00ec","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.chroma.2020.461303_bib0017","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1002\/jssc.201300576","article-title":"Optimization of the HPLC enantioseparation of 3,3\u2019-dibromo-5,5\u2019-disubstituted-4,4\u2019-bipyridines using immobilized polysaccharide-based chiral stationary phases","volume":"36","author":"Peluso","year":"2013","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2020.461303_bib0018","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1002\/jssc.201400413","article-title":"High-performance liquid chromatography enantioseparation of polyhalogenated 4,4\u2019-bipyridines on polysaccharide-based chiral stationary phases under multimodal elution","volume":"37","author":"Peluso","year":"2014","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2020.461303_bib0019","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.chroma.2014.04.040","article-title":"Insights into the impact of shape and electronic properties on the enantioseparation of polyhalogenated 4,4\u2019-bipyridines on polysaccharide-type selectors. Evidence of stereoselective halogen bonding interactions","volume":"1345","author":"Peluso","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0020","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1002\/jssc.201701206","article-title":"Polysaccharide-based chiral stationary phases as halogen bond acceptors: a novel strategy for detection of stereoselective \u03c3-hole bonds in solution","volume":"41","author":"Peluso","year":"2018","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2020.461303_bib0021","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0021-9673(00)91594-2","article-title":"High-pressure liquid chromatography on triacetylcellulose: characterization of a sorbent for the separation of enantiomers","volume":"282","author":"Koller","year":"1983","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.chroma.2020.461303_bib0022","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1039\/B517914A","article-title":"Advances in methods and algorithms in a modern quantum chemistry program package","volume":"8","author":"Shao","year":"2006","journal-title":"Phys. Chem. Chem. Phys."},{"key":"10.1016\/j.chroma.2020.461303_bib0023","series-title":"Gaussian 09, Revision B. 01","author":"Frisch","year":"2010"},{"key":"10.1016\/j.chroma.2020.461303_bib0024","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1002\/jcc.22885","article-title":"Multiwfn: a multifunctional wavefunction analyzer","volume":"33","author":"Lu","year":"2012","journal-title":"J. Comp. Chem."},{"key":"10.1016\/j.chroma.2020.461303_bib0025","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.jmgm.2012.07.004","article-title":"Quantitative analysis of molecular surface based on improved marching tetrahedra algorithm","volume":"38","author":"Lu","year":"2012","journal-title":"J. Mol. Graph. Model."},{"key":"10.1016\/j.chroma.2020.461303_bib0026","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.chroma.2016.06.007","article-title":"Insights into halogen bond-driven enantioseparations","volume":"1467","author":"Peluso","year":"2016","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0027","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.chroma.2012.06.035","article-title":"High performance liquid chromatography enantioseparation of atropisomeric 4,4\u2019-bipyridines on polysaccharide-type chiral stationary phases: impact of substituents and electronic properties","volume":"1251","author":"Peluso","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0028","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1002\/chir.22094","article-title":"Chiral recognition of N-phthaloyl, N-tetrachlorophthaloyl, and N-naphthaloyl \u03b1-amino acids and their esters on polysaccharide-derived chiral stationary phases","volume":"24","author":"Kim","year":"2012","journal-title":"Chirality"},{"key":"10.1016\/j.chroma.2020.461303_bib0029","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/chir.22202","article-title":"Comparative HPLC enantioseparation of thirty-six aromatic compounds on four columns of the Lux series: impact of substituents, shapes and electronic properties","volume":"25","author":"Peluso","year":"2013","journal-title":"Chirality"},{"key":"10.1016\/j.chroma.2020.461303_bib0030","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.chroma.2015.11.030","article-title":"Molecular-shape selectivity by naphthalimido-modified silica stationary phases: Insight into the substituents effect of naphthalene on shape recognition and \u03c0-\u03c0 interactions via electrostatic potential","volume":"1425","author":"Yamada","year":"2015","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0031","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1351\/PAC-REC-12-05-10","article-title":"Definition of the halogen bond (IUPAC recommendations 2013)","volume":"85","author":"Desiraju","year":"2013","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.chroma.2020.461303_bib0032","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.chroma.2012.10.033","article-title":"Recent developments on polysaccharide-based chiral stationary phases for liquid-phase separation of enantiomers","volume":"1269","author":"Chankvetadze","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0033","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0021-9673(97)00648-1","article-title":"3-Fluoro-, 3-chloro- and 3-bromo-5-methylphenylcarbamates of cellulose and amylose as chiral stationary phases for high performance liquid chromatographic enantioseparation","volume":"787","author":"Chankvetadze","year":"1997","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0034","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0021-9673(01)00958-X","article-title":"Enantioseparation of selected chiral sulfoxides using polysaccharide-type chiral stationary phases and polar organic, polar aqueous\u2013organic and normal-phase eluents","volume":"922","author":"Chankvetadze","year":"2001","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0035","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0021-9673(96)00698-X","article-title":"Approach to the thermodynamics of enantiomer separation by gas chromatography. Enantioselectivity between the chiral inhalation anesthetics enflurane, isoflurane and desflurane and a diluted \u03b3-cyclodextrin derivative","volume":"757","author":"Schurig","year":"1997","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0036","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1021\/ja9631458","article-title":"Thermodynamic study of an unusual chiral separation. Propranolol enantiomers on an immobilized cellulase","volume":"119","author":"Fornstedt","year":"1997","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.chroma.2020.461303_bib0037","series-title":"Fundamentals of Preparative and Nonlinear Chromatography","author":"Guiochon","year":"2006"},{"key":"10.1016\/j.chroma.2020.461303_bib0038","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1002\/jssc.200900165","article-title":"Potential of adsorption isotherm measurements for closer elucidating of binding in chiral liquid chromatographic phase systems","volume":"32","author":"Samuelsson","year":"2009","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2020.461303_bib0039","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1002\/jssc.201701264","article-title":"Van't Hoff analysis in chiral chromatography","volume":"41","author":"Asnin","year":"2018","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2020.461303_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2019.460594","article-title":"The correctness of van't Hoff plots in chiral and achiral chromatography","volume":"1611","author":"Sepsey","year":"2020","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0041","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1021\/ac961241l","article-title":"Mechanistic aspects of chiral discrimination on modified cellulose","volume":"69","author":"O'Brien","year":"1997","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2020.461303_bib0042","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.jpha.2019.04.002","article-title":"Temperature and eluent composition effects on enantiomer separation of carvedilol by high-performance liquid chromatography on immobilized amylose-based chiral stationary phases","volume":"9","author":"Panella","year":"2019","journal-title":"J. Pharm. Anal."},{"key":"10.1016\/j.chroma.2020.461303_bib0043","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/(SICI)1520-636X(1998)10:5<375::AID-CHIR3>3.0.CO;2-5","article-title":"A closer study of chiral retention mechanisms","volume":"10","author":"Fornstedt","year":"1998","journal-title":"Chirality"},{"key":"10.1016\/j.chroma.2020.461303_bib0044","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.chroma.2014.03.060","article-title":"Direct enantioseparation of underivatized aliphatic 3-hydroxyalkanoic acids with a quinine-based zwitterionic chiral stationary phase","volume":"1363","author":"Ianni","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2020.461303_bib0045","doi-asserted-by":"crossref","first-page":"5877","DOI":"10.1021\/ac034714e","volume":"75","author":"Wang","year":"2003","journal-title":"Anal. Chem."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967320305811?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967320305811?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T17:55:44Z","timestamp":1762192544000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967320305811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":45,"alternative-id":["S0021967320305811"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2020.461303","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative enantioseparation of chiral 4,4\u2019-bipyridine derivatives on coated and immobilized amylose-based chiral stationary phases","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2020.461303","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"461303"}}