{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T02:17:04Z","timestamp":1792894624928,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC1602700"],"award-info":[{"award-number":["2018YFC1602700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2019YFC1606502"],"award-info":[{"award-number":["2019YFC1606502"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21874006"],"award-info":[{"award-number":["21874006"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.chroma.2021.462606","type":"journal-article","created":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T14:08:23Z","timestamp":1633702103000},"page":"462606","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Development of a high-throughput method for the comprehensive lipid analysis in milk using ultra-high performance supercritical fluid chromatography combined with quadrupole time-of-flight mass spectrometry"],"prefix":"10.1016","volume":"1658","author":[{"given":"Yan","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Mujahid","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuechun","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4578-588X","authenticated-orcid":false,"given":"Augustine Atta","family":"Debrah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyue","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaozhen","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0708-031X","authenticated-orcid":false,"given":"Zhenxia","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2021.462606_bib0001","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1080\/10408690590957098","article-title":"Composition, structure and absorption of milk lipids: a source of energy, fat-soluble nutrients and bioactive molecules","volume":"46","author":"German","year":"2006","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.chroma.2021.462606_bib0002","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.idairyj.2019.01.005","article-title":"Comparison of bovine milk fat and vegetable fat for infant formula: Implications for infant health","volume":"92","author":"Hageman","year":"2019","journal-title":"Int. Dairy J."},{"key":"10.1016\/j.chroma.2021.462606_bib0003","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1476-511X-11-3","article-title":"Health effects of dietary phospholipids","volume":"11","author":"K\u00fcllenberg","year":"2012","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.chroma.2021.462606_bib0004","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1080\/10408398.2013.803951","article-title":"Phospholipids in human milk and infant formulas: benefits and needs for correct infant nutrition","volume":"56","author":"Cilla","year":"2016","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.chroma.2021.462606_bib0005","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.foodchem.2012.05.111","article-title":"Phospholipid fingerprints of milk from different mammalians determined by 31P NMR: towards specific interest in human health","volume":"135","author":"Garcia","year":"2012","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0006","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0958-6946(00)00026-1","article-title":"Composition of goat\u2019s milk fat triglycerides analysed by silver ion adsorption-TLC and GC\u2013MS","volume":"10","author":"Fontecha","year":"2000","journal-title":"Int. Dairy J."},{"key":"10.1016\/j.chroma.2021.462606_bib0007","doi-asserted-by":"crossref","first-page":"4571","DOI":"10.1021\/acs.jafc.8b00868","article-title":"Differences in the triacylglycerol and fatty acid compositions of human colostrum and mature milk","volume":"66","author":"Zhao","year":"2018","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2021.130414","article-title":"Investigation of alterations in phospholipids during the production chain of infant formulas via HILIC-QTOF-MS and multivariate data analysis","volume":"364","author":"Tang","year":"2021","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2021.129091","article-title":"Profiling of phospholipid molecular species in human breast milk of Chinese mothers and comprehensive analysis of phospholipidomic characteristics at different lactation stages","volume":"348","author":"Song","year":"2021","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0010","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.foodchem.2016.12.083","article-title":"Lipidomics profiling of goat milk, soymilk and bovine milk by UPLC-Q-Exactive Orbitrap Mass Spectrometry","volume":"224","author":"Li","year":"2017","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2019.125865","article-title":"Comparative lipidomics analysis of human, bovine and caprine milk by UHPLC-Q-TOF-MS","volume":"310","author":"Wang","year":"2020","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0012","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.chroma.2014.07.073","article-title":"High performance characterization of triacylglycerols in milk and milk-related samples by liquid chromatography and mass spectrometry","volume":"1360","author":"Beccaria","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0013","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1194\/jlr.M500506-JLR200","article-title":"LC-MS-based method for the qualitative and quantitative analysis of complex lipid mixtures","volume":"47","author":"Sommer","year":"2006","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.chroma.2021.462606_bib0014","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.foodchem.2016.11.139","article-title":"A comparative study of triacylglycerol composition in Chinese human milk within different lactation stages and imported infant formula by SFC coupled with Q-TOF-MS","volume":"221","author":"Tu","year":"2017","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0015","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.chroma.2015.12.075","article-title":"A simple, accurate, time-saving and green method for the determination of 15 sulfonamides and metabolites in serum samples by ultra-high performance supercritical fluid chromatography","volume":"1432","author":"Zhang","year":"2016","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0016","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/jssc.201600936","article-title":"Supercritical fluid chromatography for lipid analysis in foodstuffs","volume":"40","author":"Donato","year":"2017","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2021.462606_bib0017","first-page":"S1","article-title":"Method development for the analysis of bioactive and minor compounds from vegetable oil by supercritical fluid chromatography (SFC)","volume":"82","author":"Duval","year":"2016","journal-title":"Planta. Med."},{"key":"10.1016\/j.chroma.2021.462606_bib0018","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.chroma.2013.01.020","article-title":"Simultaneous profiling of polar lipids by supercritical fluid chromatography\/tandem mass spectrometry with methylation","volume":"1279","author":"Lee","year":"2013","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0019","doi-asserted-by":"crossref","first-page":"3553","DOI":"10.1002\/jssc.201100539","article-title":"Development of a polar lipid profiling method by supercritical fluid chromatography\/mass spectrometry","volume":"34","author":"Lee","year":"2011","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2021.462606_bib0020","doi-asserted-by":"crossref","first-page":"7187","DOI":"10.1021\/acs.analchem.5b01054","article-title":"High-throughput and comprehensive lipidomic analysis using ultrahigh-performance supercritical fluid chromatography-mass spectrometry","volume":"87","author":"Lisa","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0021","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1194\/jlr.D083014","article-title":"Widely-targeted quantitative lipidomics method by supercritical fluid chromatography triple quadrupole mass spectrometry","volume":"59","author":"Takeda","year":"2018","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.chroma.2021.462606_bib0022","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1263\/jbb.105.460","article-title":"High throughput and exhaustive analysis of diverse lipids by using supercritical fluid chromatography-mass spectrometry for metabolomics","volume":"105","author":"Bamba","year":"2008","journal-title":"J. Biosci. Bioeng."},{"key":"10.1016\/j.chroma.2021.462606_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchromb.2018.05.003","article-title":"Designs and methods for interfacing SFC with MS","volume":"1091","author":"Tarafder","year":"2018","journal-title":"J. Chromatogr. B Analyt. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.chroma.2021.462606_bib0024","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jchromb.2018.03.010","article-title":"What are the current solutions for interfacing supercritical fluid chromatography and mass spectrometry?","volume":"1083","author":"Guillarme","year":"2018","journal-title":"J. Chromatogr. B Analyt. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.chroma.2021.462606_bib0025","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0021-9673(93)83323-K","article-title":"Ion spray mass spectrometric detection for liquid chromatography: A concentration- or a mass-flow-sensitive device?","volume":"647","author":"Hopfgartner","year":"1993","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0026","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.chroma.2017.08.044","article-title":"Effects of liquid post-column addition in electrospray ionization performance in supercritical fluid chromatography-mass spectrometry","volume":"1517","author":"Akbal","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0027","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.foodchem.2011.01.123","article-title":"The chemical composition of human milk from Inner Mongolia of China","volume":"127","author":"Shi","year":"2011","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2021.462606_bib0028","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.chroma.2011.11.034","article-title":"An efficient hydrophilic interaction liquid chromatography separation of 7 phospholipid classes based on a diol column","volume":"1220","author":"Zhu","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0029","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.chroma.2016.02.052","article-title":"An improved classification of stationary phases for ultra-high performance supercritical fluid chromatography","volume":"1440","author":"West","year":"2016","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0030","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.chroma.2013.06.003","article-title":"Effects of mobile phase composition on retention and selectivity in achiral supercritical fluid chromatography","volume":"1302","author":"West","year":"2013","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0031","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.chroma.2005.04.086","article-title":"Effect of ionic additives on the elution of sodium aryl sulfonates in supercritical fluid chromatography","volume":"1082","author":"Zheng","year":"2005","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0032","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.chroma.2019.02.002","article-title":"Unravelling the effects of mobile phase additives in supercritical fluid chromatography-part II: adsorption on the stationary phase","volume":"1593","author":"West","year":"2019","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2021.462606_bib0033","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.idairyj.2016.06.005","article-title":"Addition of milk fat globule membrane as an ingredient of infant formulas for resembling the polar lipids of human milk","volume":"61","author":"Claumarchirant","year":"2016","journal-title":"Int. Dairy J."},{"key":"10.1016\/j.chroma.2021.462606_bib0034","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.idairyj.2006.06.011","article-title":"Properties, analysis and purification of milk polar lipids","volume":"16","author":"Rombaut","year":"2006","journal-title":"Int. Dairy J."},{"key":"10.1016\/j.chroma.2021.462606_bib0035","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.foodchem.2016.02.163","article-title":"Identification and quantification of phosphatidylinositol in infant formulas by liquid chromatography-mass spectrometry","volume":"205","author":"Liu","year":"2016","journal-title":"Food Chem."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967321007305?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967321007305?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T06:09:07Z","timestamp":1758262147000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967321007305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":35,"alternative-id":["S0021967321007305"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2021.462606","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of a high-throughput method for the comprehensive lipid analysis in milk using ultra-high performance supercritical fluid chromatography combined with quadrupole time-of-flight mass spectrometry","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2021.462606","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"462606"}}