{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:34:26Z","timestamp":1781829266344,"version":"3.54.5"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003130","name":"FWO","doi-asserted-by":"publisher","award":["30897864"],"award-info":[{"award-number":["30897864"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002661","name":"Fonds De La Recherche Scientifique - FNRS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.chroma.2024.464765","type":"journal-article","created":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T22:04:59Z","timestamp":1708725899000},"page":"464765","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Temperature-responsive comprehensive two-dimensional liquid chromatography coupled to high resolution mass spectrometry for the elucidation of the oxidative degradation processes of chemicals of environmental concern"],"prefix":"10.1016","volume":"1719","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8057-3228","authenticated-orcid":false,"given":"Elena","family":"Bandini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Wicht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2782-0434","authenticated-orcid":false,"given":"Maike Felipe Santos","family":"Barbetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamed","family":"Eghbali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4690-7690","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Lynen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2024.464765_bib0001","doi-asserted-by":"crossref","first-page":"7697","DOI":"10.1039\/C5AY01143D","article-title":"A comparison of one-dimensional and microscale two-dimensional liquid chromatographic approaches coupled to high resolution mass spectrometry for the analysis of complex samples","volume":"7","author":"Leonhardt","year":"2015","journal-title":"Analyt. Methods"},{"key":"10.1016\/j.chroma.2024.464765_bib0002","first-page":"1644","article-title":"A comprehensive two-dimensional liquid chromatography method for the simultaneous separation of lipid species and their oxidation products","author":"Lazaridi","year":"2021","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2024.464765_bib0003","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00253-012-3929-z","article-title":"New developments in the trace analysis of organic water pollutants","volume":"94","author":"Fischer","year":"2012","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.chroma.2024.464765_bib0004","first-page":"241","article-title":"Assessment of automated off-line solid-phase extraction LC-MS\/MS to monitor EPA priority endocrine disruptors in tap water, surface water, and wastewater","author":"Goeury","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.chroma.2024.464765_bib0005","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.trac.2013.03.011","article-title":"Application of LC-MS to the analysis of advanced oxidation process (AOP) degradation of dye products and reaction mechanisms","volume":"49","author":"Hisaindee","year":"2013","journal-title":"TrAC - Trends Anal. Chem."},{"key":"10.1016\/j.chroma.2024.464765_bib0006","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1021\/acs.analchem.8b04841","article-title":"Recent developments in two-dimensional liquid chromatography: fundamental improvements for practical applications","volume":"91","author":"Pirok","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2024.464765_bib0007","first-page":"272","article-title":"Environmental and health impacts of contaminants of emerging concerns: recent treatment challenges and approaches","author":"Yadav","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.chroma.2024.464765_bib0008","series-title":"Advanced Oxidation Processes For Wastewater Treatment: Emerging Green Chemical Technology","author":"Ameta","year":"2018"},{"key":"10.1016\/j.chroma.2024.464765_bib0009","doi-asserted-by":"crossref","first-page":"6222","DOI":"10.1021\/es300897u","article-title":"Enhanced biodegradation of carbamazepine after UV\/H2O 2 advanced oxidation","volume":"46","author":"Keen","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2024.464765_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2021.114465","article-title":"On-line 2D-RPLC x RPLC \u2013 HRMS to assess wastewater treatment in a pharmaceutical plant","volume":"208","author":"Saint Germain","year":"2022","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2024.464765_bib0011","doi-asserted-by":"crossref","DOI":"10.1007\/s11274-021-02998-4","article-title":"Assessing the bioremediation potential of indigenously isolated Klebsiella sp. WAH1 for diclofenac sodium: optimization, toxicity and metabolic pathway studies","volume":"37","author":"Sharma","year":"2021","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.chroma.2024.464765_bib0012","doi-asserted-by":"crossref","first-page":"242","DOI":"10.56530\/lcgc.eu.dy3481z3","article-title":"Practical approaches to overcome the challenges of comprehensive two-dimensional liquid chromatography","author":"Pirok","year":"2018","journal-title":"LCGC Europe"},{"key":"10.1016\/j.chroma.2024.464765_bib0013","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/jssc.202100534","article-title":"Strategies to circumvent the solvent strength mismatch problem in online comprehensive two-dimensional liquid chromatography","volume":"45","author":"Chapel","year":"2022","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2024.464765_bib0014","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.talanta.2018.11.030","article-title":"Quantitative aspects in on-line comprehensive two-dimensional liquid chromatography for pharmaceutical applications","volume":"195","author":"Iguiniz","year":"2019","journal-title":"Talanta"},{"key":"10.1016\/j.chroma.2024.464765_bib0015","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.1021\/acs.analchem.7b04914","article-title":"Enhancing the possibilities of comprehensive two-dimensional liquid chromatography through hyphenation of purely aqueous temperature-responsive and reversed-phase liquid chromatography","volume":"90","author":"Baert","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2024.464765_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2022.340441","article-title":"Hyphenating temperature gradient elution with refractive index detection through temperature-responsive liquid chromatography","volume":"1231","author":"Bandini","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.chroma.2024.464765_bib0017","doi-asserted-by":"crossref","unstructured":"F. Lynen, A. Ampe, E. Bandini, M. Baert, K. Wicht, A. Kajtazi, T. Rahmani, J. Veenhoven, G. Spileers, Perspectives in hydrophobic interaction temperature- responsive liquid chromatography (TRLC), LCGC North America (2022) 566\u2013572. https:\/\/doi.org\/10.56530\/lcgc.na.vd2373d8.","DOI":"10.56530\/lcgc.na.vd2373d8"},{"key":"10.1016\/j.chroma.2024.464765_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2020.461561","article-title":"Pharmaceutical impurity analysis by comprehensive two-dimensional temperature responsive \u00d7 reversed phase liquid chromatography","volume":"1630","author":"Wicht","year":"2020","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2024.464765_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2021.122889","article-title":"Comprehensive two-dimensional temperature-responsive \u00d7 reversed phase liquid chromatography for the analysis of wine phenolics","volume":"236","author":"Wicht","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.chroma.2024.464765_bib0020","doi-asserted-by":"crossref","first-page":"8763","DOI":"10.1021\/acs.analchem.3c00780","article-title":"Temperature responsive \u00d7 fast chiral comprehensive liquid chromatography: a New 2D-LC platform for resolving mixtures of chiral isomers","volume":"95","author":"Rahmani","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2024.464765_bib0021","doi-asserted-by":"crossref","first-page":"248","DOI":"10.56530\/lcgc.na.vm4090l5","article-title":"Possibilities and limitations of aqueous temperature responsive liquid chromatography in comprehensive 2D\u2013LC","author":"Lynen","year":"2023","journal-title":"LCGC North America"},{"key":"10.1016\/j.chroma.2024.464765_bib0022","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1365\/s10337-007-0301-z","article-title":"Evaluation of the temperature responsive stationary phase poly(N-isopropylacrylamide) in aqueous LC for the analysis of small molecules","volume":"66","author":"Lynen","year":"2007","journal-title":"Chromatographia"},{"key":"10.1016\/j.chroma.2024.464765_bib0023","doi-asserted-by":"crossref","DOI":"10.1021\/acs.analchem.0c01321","article-title":"Exploration of the selectivity and retention behavior of alternative polyacrylamides in temperature responsive liquid chromatography","author":"Baert","year":"2020","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2024.464765_bib0024","series-title":"Two-Dimensional Liquid Chromatography","author":"Carr","year":"2015"},{"key":"10.1016\/j.chroma.2024.464765_bib0025","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s10311-010-0285-z","article-title":"Removal of carbamazepine from urban wastewater by sulfate radical oxidation","volume":"9","author":"Matta","year":"2011","journal-title":"Environ. Chem. Lett."},{"key":"10.1016\/j.chroma.2024.464765_bib0026","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.psep.2017.07.015","article-title":"Photolysis and UV\/H2O2 of diclofenac, sulfamethoxazole, carbamazepine, and trimethoprim: identification of their major degradation products by ESI\u2013LC\u2013MS and assessment of the toxicity of reaction mixtures","volume":"112","author":"Alharbi","year":"2017","journal-title":"Process Saf. Environ. Prot."},{"key":"10.1016\/j.chroma.2024.464765_bib0027","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.scitotenv.2019.06.011","article-title":"Effect of alpha-hydroxy acids on transformation products formation and degradation mechanisms of carbamazepine by UV\/H2O2 process","volume":"689","author":"Lu","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chroma.2024.464765_bib0028","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.apcata.2013.08.050","article-title":"Photocatalytic oxidation of carbamazepine in triclinic-WO3 suspension: role of alcohol and sulfate radicals in the degradation pathway","volume":"468","author":"Rao","year":"2013","journal-title":"Appl. Catal. A Gen."},{"key":"10.1016\/j.chroma.2024.464765_bib0029","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.jhazmat.2016.09.053","article-title":"Carbamazepine degradation by gamma irradiation coupled to biological treatment","volume":"321","author":"Wang","year":"2017","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2024.464765_bib0030","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/j.watres.2010.10.037","article-title":"Direct photodegradation of carbamazepine followed by micellar electrokinetic chromatography and mass spectrometry","volume":"45","author":"Calisto","year":"2011","journal-title":"Water. Res."},{"key":"10.1016\/j.chroma.2024.464765_bib0031","doi-asserted-by":"crossref","first-page":"5977","DOI":"10.1021\/es060502y","article-title":"Photodegradation processes of the antiepileptic drug carbamazepine, relevant to estuarine waters","volume":"40","author":"Chiron","year":"2006","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2024.464765_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146498","article-title":"The degradation pathways of carbamazepine in advanced oxidation process: a mini review coupled with DFT calculation","volume":"779","author":"Li","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chroma.2024.464765_bib0033","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.cej.2011.04.002","article-title":"Degradation of aqueous carbamazepine in ultrasonic\/Fe0\/H2O2 systems","volume":"172","author":"Ghauch","year":"2011","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.chroma.2024.464765_bib0034","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.psep.2018.05.004","article-title":"Carbamazepine degradation by UV and UV-assisted AOPs: kinetics, mechanism and toxicity investigations","volume":"117","author":"Ali","year":"2018","journal-title":"Process Saf. Environ. Prot."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967324001389?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967324001389?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T18:03:53Z","timestamp":1762193033000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967324001389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":34,"alternative-id":["S0021967324001389"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2024.464765","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Temperature-responsive comprehensive two-dimensional liquid chromatography coupled to high resolution mass spectrometry for the elucidation of the oxidative degradation processes of chemicals of environmental concern","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2024.464765","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"464765"}}