{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T19:17:58Z","timestamp":1770146278296,"version":"3.49.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373634"],"award-info":[{"award-number":["82373634"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008047","name":"Hebei University","doi-asserted-by":"publisher","award":["IT2023A06"],"award-info":[{"award-number":["IT2023A06"]}],"id":[{"id":"10.13039\/501100008047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.chroma.2025.466196","type":"journal-article","created":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T17:51:16Z","timestamp":1751824276000},"page":"466196","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Green synthesis of a urea\u2013melamine\u2013hexamethylenetetramine resin for efficient extraction and determination of berberine hydrochloride in Pudilan antiphlogistic oral liquid"],"prefix":"10.1016","volume":"1758","author":[{"given":"Hui","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinku","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Di","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhezhe","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinbei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyuan","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehong","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"15","key":"10.1016\/j.chroma.2025.466196_bib0001","article-title":"Differential absorption and metabolic characteristics of organic acid components in pudilan xiaoyan oral liquid between young rats and adult rats","volume":"334","author":"Yang","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.chroma.2025.466196_bib0002","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s13020-023-00853-2","article-title":"Network pharmacology: a bright guiding light on the way to explore the personalized precise medication of traditional Chinese medicine","volume":"18","author":"Li","year":"2023","journal-title":"Chin. Med."},{"issue":"6","key":"10.1016\/j.chroma.2025.466196_bib0003","doi-asserted-by":"crossref","first-page":"6770","DOI":"10.1021\/acsnano.9b01346","article-title":"Natural berberine-based Chinese herb medicine assembled nanostructures with modified antibacterial application","volume":"13","author":"Li","year":"2019","journal-title":"ACS Nano"},{"issue":"10","key":"10.1016\/j.chroma.2025.466196_bib0004","article-title":"A novel strategy for active compound efficacy status identification in multi-tropism Chinese herbal medicine (Scutellaria baicalensis Georgi) based on multi-indexes spectrum-effect gray correlation analysis","volume":"300","author":"Deng","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"5","key":"10.1016\/j.chroma.2025.466196_bib0005","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.jpha.2022.05.001","article-title":"Multimodal integrated strategy for the discovery and identification of quality markers in traditional Chinese medicine","volume":"12","author":"Lu","year":"2022","journal-title":"J. Pharm. Anal."},{"key":"10.1016\/j.chroma.2025.466196_bib0006","first-page":"1609","article-title":"A classification of liquid chromatography mass spectrometry techniques for evaluation of chemical composition and quality control of traditional medicine","author":"Andrey","year":"2020","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2025.466196_bib0007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10408347.2024.2431222","article-title":"Quality consistency evaluation of traditional Chinese medicines: current status and future perspectives","author":"Liu","year":"2024","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.chroma.2025.466196_bib0008","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.talanta.2007.05.048","article-title":"Supramolecular interaction of ethylenediamine linked \u03b2-cyclodextrin dimer and berberine hydrochloride by spectrofluorimetry and its analytical application","volume":"74","author":"Liu","year":"2007","journal-title":"Talanta"},{"key":"10.1016\/j.chroma.2025.466196_bib0009","doi-asserted-by":"crossref","first-page":"2678","DOI":"10.3390\/pr10122678","article-title":"Determination of 7 kinds of alkaloids in semen nelumbinis and its products by HPLC","volume":"10","author":"Zhong","year":"2022","journal-title":"Processes"},{"key":"10.1016\/j.chroma.2025.466196_bib0010","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1002\/jssc.202001026","article-title":"Preparation of a zirconium terephthalate metal-organic framework coated magnetic nanoparticle for the extraction of berberine prior to high-performance liquid chromatography analysis","volume":"44","author":"Wang","year":"2021","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2025.466196_bib0011","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.talanta.2012.10.014","article-title":"Preparation of micropipette tip-based molecularly imprinted monolith for selective micro-solid phase extraction of berberine in plasma and urine samples","volume":"103","author":"Zhang","year":"2013","journal-title":"Talanta"},{"issue":"8","key":"10.1016\/j.chroma.2025.466196_bib0012","first-page":"54","article-title":"Determination of three alkaloids in jinji granules by SPE-HPLC","volume":"18","author":"Bing","year":"2011","journal-title":"Chin. J. Info. Tradit. Chin. Med."},{"issue":"5","key":"10.1016\/j.chroma.2025.466196_bib0013","first-page":"650","article-title":"Saturated flow-through mode in SPE to determine berberine in huanglian shangqing pills by HPLC-UV","volume":"27","author":"Yong","year":"2007","journal-title":"J. Pharm. Anal."},{"key":"10.1016\/j.chroma.2025.466196_bib0014","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jhazmat.2015.11.022","article-title":"Moisture insensitive adsorption of ammonia on resorcinol-formaldehyde resins","volume":"305","author":"Seredych","year":"2016","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2025.466196_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.145043","article-title":"A compressible and underwater superelastic hydrophilic molecularly imprinted resin composite cellulose nanofiber aerogel to separate and purify catechins from tea","volume":"472","author":"Ma","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.chroma.2025.466196_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.139341","article-title":"Green synthesis of superhydrophilic resin\/graphene oxide for efficient analysis of multiple pesticide residues in fruits and vegetables","volume":"450","author":"Yuan","year":"2024","journal-title":"Food Chem."},{"issue":"41","key":"10.1016\/j.chroma.2025.466196_bib0017","doi-asserted-by":"crossref","DOI":"10.1002\/app.48038","article-title":"Effect of a novel environmentally friendly additive of polyaspartic acid on the properties of urea formaldehyde resins\/montmorillonite","volume":"136","author":"Zhou","year":"2019","journal-title":"J. Appl. Polym. Sci."},{"key":"10.1016\/j.chroma.2025.466196_bib0018","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.cej.2015.12.007","article-title":"A novel fabrication of monodisperse melamine\u2212formaldehyde resin microspheres to adsorb lead (II)","volume":"288","author":"Guang","year":"2016","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.chroma.2025.466196_bib0019","doi-asserted-by":"crossref","first-page":"3763","DOI":"10.1039\/c3cc41109e","article-title":"Facile preparation and ultra-microporous structure of melamine-resorcinol-formaldehyde polymeric microspheres","volume":"49","author":"Zhou","year":"2013","journal-title":"Chem. Commun."},{"key":"10.1016\/j.chroma.2025.466196_bib0020","article-title":"A novel colorless flexible polymer aerogel with stable amine linkage enabled superior formaldehyde removal and multifunctional application","volume":"500","author":"Wang","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.chroma.2025.466196_bib0021","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/s41586-023-06507-5","article-title":"Bonding wood with uncondensed lignins as adhesives","volume":"621","author":"Yang","year":"2023","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.chroma.2025.466196_bib0022","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1039\/D3GC04207C","article-title":"Facile and green synthesis of a hydrophilic imprinted resin in a deep eutectic solvent\u2013water medium for the specific molecular recognition of tumor biomarkers in complex biological matrices","volume":"26","author":"Wang","year":"2024","journal-title":"Green Chem."},{"key":"10.1016\/j.chroma.2025.466196_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.139677","article-title":"Molecularly imprinted resin modified with ionic liquid for dispersive filter extraction and determination of perfluoroalkyl acids in eggs","volume":"453","author":"Lu","year":"2024","journal-title":"Food Chem."},{"issue":"24","key":"10.1016\/j.chroma.2025.466196_bib0024","doi-asserted-by":"crossref","DOI":"10.1002\/app.53956","article-title":"Optimizing the dielectric and mechanical properties of melamine based-benzoxazine resin by copolymerizing with epoxy resin","volume":"140","author":"Ye","year":"2023","journal-title":"J. Appl. Polym. Sci."},{"key":"10.1016\/j.chroma.2025.466196_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2023.123762","article-title":"Cost-effective removal of Cr (VI) ions from aqueous media using l-cysteine functionalized gold nanoparticles embedded in melamine-based covalent organic framework (Cys-AuNPs@COF)","volume":"308","author":"Rashidi","year":"2024","journal-title":"Spectrochim. Acta A."},{"issue":"24","key":"10.1016\/j.chroma.2025.466196_bib0026","doi-asserted-by":"crossref","first-page":"3578","DOI":"10.3390\/polym16243578","article-title":"Preparation and characterization of melamine aniline formaldehyde-organo clay nanocomposite foams (MAFOCF) as a novel thermal insulation material","volume":"16","author":"G\u00fcrses","year":"2024","journal-title":"Polym. (Basel)"},{"key":"10.1016\/j.chroma.2025.466196_bib0027","article-title":"Sustainable application of functionalized resins in adsorbing and recycling aromatic compounds from complex wastewater systems: exploration of synthesis strategies, performance predictions, and interaction mechanisms","volume":"361","author":"Yang","year":"2024","journal-title":"Sep. Purif. Technol."},{"issue":"7","key":"10.1016\/j.chroma.2025.466196_bib0028","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jmgm.2016.05.005","article-title":"A theoretical study of \u03c0\u2013stacking interactions in C\u2013substituted tetrazoles","volume":"6","author":"Farrokhzadeh","year":"2016","journal-title":"J. Mol. Graph. Model"},{"key":"10.1016\/j.chroma.2025.466196_bib0029","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.comptc.2014.09.022","article-title":"Ab initio study of the \u03c0\u2013\u03c0 interaction in the pyridine dimer: effects of bond functions","volume":"1049","author":"Zhang","year":"2014","journal-title":"Comput. Theor. Chem."},{"key":"10.1016\/j.chroma.2025.466196_bib0030","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.molstruc.2015.01.020","article-title":"luminescent properties, internal hydrogen bonds and \u03c0\u2013\u03c0 interactions of Cd (II), Zn (II), Co (II) complexes based on 2,8\u2013di (pyridin\u20134\u2013yl) dibenzothiophene and dicarboxylate ligands","volume":"1086","author":"Huang","year":"2015","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.chroma.2025.466196_bib0031","first-page":"1","article-title":"Wet-spinning preparation of high-performance phenol-modified melamine-formaldehyde fibers","author":"Li","year":"2024","journal-title":"J. Macromol. Sci. B."},{"issue":"19","key":"10.1016\/j.chroma.2025.466196_bib0032","doi-asserted-by":"crossref","first-page":"7441","DOI":"10.1039\/D3GC02948D","article-title":"A review of the green chemistry approaches to leather tanning in imparting sustainable leather manufacturing","volume":"25","author":"Hassan","year":"2023","journal-title":"Green Chem."},{"issue":"6","key":"10.1016\/j.chroma.2025.466196_bib0033","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1007\/s10934-017-0395-0","article-title":"Solvothermal polycondensation of novolacs phenolic-resin to nanopowders and their derived activated nanocarbons as efficient adsorbents for water cleaning","volume":"24","author":"Zou","year":"2017","journal-title":"J. Porous Mater."},{"issue":"2","key":"10.1016\/j.chroma.2025.466196_bib0034","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jfoodeng.2011.05.023","article-title":"Physical, mechanical and antibacterial properties of alginate film: effect of the crosslinking degree and oregano essential oil concentration","volume":"110","author":"Benavides","year":"2012","journal-title":"J. Food Eng."},{"issue":"1","key":"10.1016\/j.chroma.2025.466196_bib0035","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jhazmat.2008.06.069","article-title":"Adsorption isotherm and kinetic modeling of 2.4-D pesticide on activated carbon derived from date stones","volume":"163","author":"Hameed","year":"2009","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2025.466196_bib0036","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jhazmat.2016.02.045","article-title":"Adsorption behavior and mechanism of chloramphenicols, sulfonamides, and non-antibiotic pharmaceuticals on multi-walled carbon nanotubes","volume":"310","author":"Zhao","year":"2016","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2025.466196_bib0037","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1002\/jssc.201500440","article-title":"Development of a method using high-performance liquid chromatographic fingerprint and multi-ingredients quantitative analysis for the quality control of Yangxinshi Pian","volume":"38","author":"Li","year":"2015","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2025.466196_bib0038","doi-asserted-by":"crossref","first-page":"6075","DOI":"10.1039\/C7RA13048A","article-title":"Determination of berberine hydrochloride using a fluorimetric method with silica nanoparticles as a probe","volume":"8","author":"Liu","year":"2018","journal-title":"RSC Adv."},{"key":"10.1016\/j.chroma.2025.466196_bib0039","doi-asserted-by":"crossref","first-page":"7928","DOI":"10.1039\/C4AY01442A","article-title":"Simultaneous determination of berberine and palmatine in human plasma and in urine by capillary electrophoresis combined with polypropylene hollow fiber liquid\u2013liquid\u2013liquid microextraction","volume":"6","author":"Song","year":"2014","journal-title":"Anal. Methods"},{"issue":"18","key":"10.1016\/j.chroma.2025.466196_bib0040","first-page":"88","article-title":"Automated online-SPE-HPLC for rapid determination of the content of berberine in the Chinese traditional medicine compound","volume":"18","author":"Li","year":"2012","journal-title":"Chin. J. Exp. Tradit. Med. Form"},{"issue":"1","key":"10.1016\/j.chroma.2025.466196_bib0041","first-page":"342","article-title":"Fast determination of berberine hydrochloride and robenidine hydrochloride in fish meat","volume":"22","author":"Zhu","year":"2022","journal-title":"J. Chin. Inst. Food Sci. Technol."},{"issue":"5","key":"10.1016\/j.chroma.2025.466196_bib0042","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1093\/chromsci\/bmv244","article-title":"Determination of mycotoxins in brown rice using QuEChERS sample preparation and UHPLC\u2013MS-MS","volume":"54","author":"Jettanajit","year":"2016","journal-title":"J. Chromatogr. Sci."},{"key":"10.1016\/j.chroma.2025.466196_bib0043","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s10337-020-04000-z","article-title":"Application of simultaneously validated UHPLCPDA and LC\u2013ESI\u2013MS\/MS methods for determining 22 antidepressants and anxiolytics in food matrix samples","volume":"84","author":"Kim","year":"2021","journal-title":"Chromatographia"}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967325005424?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967325005424?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T14:16:43Z","timestamp":1762265803000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967325005424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":43,"alternative-id":["S0021967325005424"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2025.466196","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Green synthesis of a urea\u2013melamine\u2013hexamethylenetetramine resin for efficient extraction and determination of berberine hydrochloride in Pudilan antiphlogistic oral liquid","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2025.466196","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"466196"}}