{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:22:43Z","timestamp":1778286163927,"version":"3.51.4"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004572","name":"National Health Commission of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004572","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.chroma.2026.466728","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:42:52Z","timestamp":1769042572000},"page":"466728","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Determination of 15 phthalates metabolites and 9 bisphenols in human serum by using high-performance liquid chromatography coupled with tandem mass spectrometry"],"prefix":"10.1016","volume":"1769","author":[{"given":"Yilin","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuangzhuang","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dejun","family":"Bao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojian","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.chroma.2026.466728_bib0001","doi-asserted-by":"crossref","first-page":"12875","DOI":"10.1007\/s13762-022-04636-4","article-title":"A global overview of endocrine disrupting chemicals in the environment: occurrence, effects, and treatment methods","volume":"20","author":"Puri","year":"2022","journal-title":"Int. J. Environ. Sci. Technol."},{"issue":"7","key":"10.1016\/j.chroma.2026.466728_bib0002","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.1021\/acs.est.2c07611","article-title":"Association of endocrine-disrupting chemicals with all-cause and cause-specific mortality in the U.S.: A prospective cohort study","volume":"57","author":"Fan","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"10","key":"10.1016\/j.chroma.2026.466728_bib0003","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/s41574-023-00872-x","article-title":"The regulation of endocrine-disrupting chemicals to minimize their impact on health","volume":"19","author":"Duh-Leong","year":"2023","journal-title":"Nat. Rev. Endocrinol."},{"issue":"5","key":"10.1016\/j.chroma.2026.466728_bib0004","article-title":"Endocrine-disrupting chemicals","volume":"35","author":"Kiess","year":"2021","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.chroma.2026.466728_bib0005","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1021\/envhealth.3c00202","article-title":"Environmental obesogens and their perturbations in lipid metabolism","volume":"2","author":"Wang","year":"2024","journal-title":"Environ. Health"},{"issue":"4","key":"10.1016\/j.chroma.2026.466728_bib0006","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/s41574-024-00958-0","article-title":"Endocrine disrupting chemicals are a threat to hormone health: A commentary on behalf of the ESE","volume":"20","author":"Reincke","year":"2024","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.chroma.2026.466728_bib0007","article-title":"Occurrence patterns of bisphenol analogues in human blood, subcutaneous fat, and visceral fat","author":"Jiao","year":"2025","journal-title":"Environ. Health"},{"issue":"13","key":"10.1016\/j.chroma.2026.466728_bib0008","doi-asserted-by":"crossref","first-page":"6708","DOI":"10.1021\/acs.est.4c10394","article-title":"Occurrence, characteristics, and mixed reproductive exposure risk assessment of traditional phthalates and their novel alternatives in campus indoor dust","volume":"59","author":"Gao","year":"2025","journal-title":"Environ. Sci. Technol."},{"issue":"2","key":"10.1016\/j.chroma.2026.466728_bib0009","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1021\/acs.estlett.4c01002","article-title":"Cigarette filters-A neglected source of phthalate exposure to humans","volume":"12","author":"Zhang","year":"2025","journal-title":"Environ. Sci. Technol. Lett."},{"issue":"2","key":"10.1016\/j.chroma.2026.466728_bib0010","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1111\/1541-4337.13113","article-title":"Endocrine modulating chemicals in food packaging: A review of phthalates and bisphenols","volume":"22","author":"Tumu","year":"2023","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"issue":"3","key":"10.1016\/j.chroma.2026.466728_bib0011","doi-asserted-by":"crossref","DOI":"10.1289\/EHP11760","article-title":"Effects of behavioral, clinical, and policy interventions in reducing human exposure to bisphenols and phthalates: A scoping review","volume":"132","author":"Sieck","year":"2024","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chroma.2026.466728_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.108294","article-title":"Worldwide risk assessment of phthalates and bisphenol A in humans: the need for updating guidelines","volume":"181","author":"Due\u00f1as-Moreno","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.chroma.2026.466728_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2024.107230","article-title":"Neurodevelopmental toxicity and mechanism of action of monoethylhexyl phthalate (MEHP) in the developing zebrafish (Danio rerio)","volume":"279","author":"Wu","year":"2025","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.chroma.2026.466728_bib0014","article-title":"Developmental mono (2-ethylhexyl) phthalate exposure impairs offspring neurobehavior through suppression of CYP450 transcriptional pathways","author":"Dong","year":"2025","journal-title":"Environ. Health"},{"key":"10.1016\/j.chroma.2026.466728_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.118702","article-title":"Transgenerational hepatotoxicity induced by bisphenol B as a substitute for bisphenol A","volume":"302","author":"Yue","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.chroma.2026.466728_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.112109","article-title":"Phthalate exposure and risk of diabetes mellitus: implications from a systematic review and meta-analysis","volume":"204","author":"Zhang","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.chroma.2026.466728_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121853","article-title":"Bisphenol and phthalate exposure during pregnancy and the development of childhood lung function and asthma. The Generation R Study","volume":"332","author":"Karramass","year":"2023","journal-title":"Environ. Pollut."},{"issue":"6582","key":"10.1016\/j.chroma.2026.466728_bib0018","doi-asserted-by":"crossref","DOI":"10.1126\/science.abe8244","article-title":"From cohorts to molecules: adverse impacts of endocrine disrupting mixtures","volume":"375","author":"Caporale","year":"2022","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.chroma.2026.466728_bib0019","doi-asserted-by":"crossref","DOI":"10.1289\/EHP10293","article-title":"Maternal phthalate and bisphenol urine concentrations during pregnancy and early markers of arterial health in children","volume":"130","author":"Blaauwendraad","year":"2022","journal-title":"Environ. Health Perspect."},{"issue":"4","key":"10.1016\/j.chroma.2026.466728_bib0020","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1021\/acs.est.6b05718","article-title":"Bisphenol A metabolites and bisphenol S in paired maternal and cord serum","volume":"51","author":"Liu","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2026.466728_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.127487","article-title":"Bisphenol exposure during pregnancy and serum total bile acid levels across trimesters: single and combined effects in pregnant women from Guangxi Zhuang, China","volume":"390","author":"Liang","year":"2026","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chroma.2026.466728_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2019.120144","article-title":"A multi-residue method for determination of 36 endocrine disrupting chemicals in human serum with a simple extraction procedure in combination of UPLC-MS\/MS analysis","volume":"205","author":"Wang","year":"2019","journal-title":"Talanta"},{"key":"10.1016\/j.chroma.2026.466728_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.119305","article-title":"Phthalates exposure as a risk factor for gestational diabetes mellitus: integrated evidence from epidemiological and human liver organoids studies","volume":"306","author":"Liu","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.chroma.2026.466728_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.136991","article-title":"Typical endocrine disrupting chemicals in newborns with congenital hypothyroidism: concentrations, exposure assessment, and potential risks","volume":"486","author":"Chen","year":"2025","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.chroma.2026.466728_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2021.462079","article-title":"Determination of 21 photoinitiators in human plasma by using high-performance liquid chromatography coupled with tandem mass spectrometry: A systemically validation and application in healthy volunteers","volume":"1643","author":"Li","year":"2021","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466728_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2025.466234","article-title":"A reliable UHPLC-MS\/MS method for the determination of legacy and emerging bisphenol analogues in human urine","volume":"1759","author":"Lin","year":"2025","journal-title":"J. Chromatogr. A"},{"issue":"12","key":"10.1016\/j.chroma.2026.466728_bib0027","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1021\/acs.estlett.9b00626","article-title":"Photoinitiators in breast milk from United States donors: occurrence and implications for exposure in infants","volume":"6","author":"Liu","year":"2019","journal-title":"Environ. Sci. Technol. Lett."},{"issue":"18","key":"10.1016\/j.chroma.2026.466728_bib0028","doi-asserted-by":"crossref","first-page":"10969","DOI":"10.1021\/acs.est.9b03127","article-title":"Occurrence and distribution of photoinitiator additives in paired maternal and cord plasma in a South China population","volume":"53","author":"Li","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2026.466728_bib0029","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.chroma.2019.06.045","article-title":"Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of 17 traditional and emerging aryl organophosphate esters in indoor dust","volume":"1603","author":"Du","year":"2019","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466728_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114005","article-title":"Investigation of phthalate metabolites in urine and daily phthalate intakes among three age groups in Beijing, China","volume":"260","author":"Zhang","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chroma.2026.466728_bib0031","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.envres.2015.11.029","article-title":"Urinary biomarkers of exposure to 57 xenobiotics and its association with oxidative stress in a population in Jeddah, Saudi Arabia","volume":"150","author":"Asimakopoulos","year":"2016","journal-title":"Environ. Res."},{"issue":"23","key":"10.1016\/j.chroma.2026.466728_bib0032","doi-asserted-by":"crossref","DOI":"10.1002\/jssc.202300571","article-title":"Matrix effects demystified: strategies for resolving challenges in analytical separations of complex samples","volume":"46","author":"Williams","year":"2023","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2026.466728_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2021.122716","article-title":"Development and validation of a micro-QuEChERS method with high-throughput enhanced matrix removal followed with UHPLC-QqQ-MS\/MS for analysis of raspberry ketone-related phenolic compounds in adipose tissues","volume":"235","author":"Yuan","year":"2021","journal-title":"Talanta"},{"issue":"17","key":"10.1016\/j.chroma.2026.466728_bib0034","doi-asserted-by":"crossref","first-page":"10089","DOI":"10.1021\/acs.est.8b02457","article-title":"First detection of photoinitiators and metabolites in human sera from united states donors","volume":"52","author":"Liu","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2026.466728_bib0035","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.talanta.2016.01.037","article-title":"Rapid, automated online SPE-LC-QTRAP-MS\/MS method for the simultaneous analysis of 14 phthalate metabolites and 5 bisphenol analogues in human urine","volume":"151","author":"Heffernan","year":"2016","journal-title":"Talanta"},{"key":"10.1016\/j.chroma.2026.466728_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2024.465096","article-title":"Determination of nine bisphenol analogues in human urine by high-throughput solid-phase extraction and ultra-high performance liquid chromatography-tandem mass spectrometry analysis","volume":"1730","author":"Jin","year":"2024","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466728_bib0037","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.scitotenv.2018.02.148","article-title":"Determination of trace levels of eleven bisphenol A analogues in human blood serum by high performance liquid chromatography\u2013tandem mass spectrometry","volume":"628-629","author":"Owczarek","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chroma.2026.466728_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.159570","article-title":"Serum concentrations of phthalate metabolites in pregnant women and their association with gestational diabetes mellitus and blood glucose levels","volume":"857","author":"Wang","year":"2023","journal-title":"Sci. Total Environ."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326000580?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326000580?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T21:06:56Z","timestamp":1770239216000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967326000580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":38,"alternative-id":["S0021967326000580"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2026.466728","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Determination of 15 phthalates metabolites and 9 bisphenols in human serum by using high-performance liquid chromatography coupled with tandem mass spectrometry","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2026.466728","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"466728"}}