{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T19:24:46Z","timestamp":1780514686465,"version":"3.54.1"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.chroma.2026.466996","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T06:05:11Z","timestamp":1776233111000},"page":"466996","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Automated solid-phase extraction coupled with heart-cutting two\u2011dimensional liquid chromatography for simultaneous quantification of thirteen fat-soluble vitamins in foods for special medical purposes"],"prefix":"10.1016","volume":"1778","author":[{"given":"Lulu","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiqi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijian","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huadong","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuifeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2026.466996_bib0001","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.tifs.2020.04.007","article-title":"Food ingredients in human health: ecological and metabolic perspectives implicating gut microbiota function","volume":"100","author":"Wu","year":"2020","journal-title":"Trends Food Sci. Technol."},{"key":"10.1016\/j.chroma.2026.466996_bib0002","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.3390\/nu11112823","article-title":"Dietary trace minerals","volume":"11","author":"Tako","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.chroma.2026.466996_bib0003","doi-asserted-by":"crossref","DOI":"10.1111\/1541-4337.70005","article-title":"Potential of 3D printing in development of foods for special medical purpose: a review","volume":"23","author":"Shi","year":"2024","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.chroma.2026.466996_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.advnut.2025.100546","article-title":"Bioactives in food-As-medicine for special medical purposes","volume":"16","author":"Xi","year":"2025","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.chroma.2026.466996_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.crfs.2025.101055","article-title":"Stability of nutrients in complex liquid and powder food matrices: learnings from shelf-life studies in foods for special medical purposes","volume":"10","author":"Ameye","year":"2025","journal-title":"Curr. Res. Food Sci."},{"key":"10.1016\/j.chroma.2026.466996_bib0006","doi-asserted-by":"crossref","first-page":"505","DOI":"10.3390\/ph17040505","article-title":"Development and validation of novel HPLC methods for quantitative determination of vitamin D3 in tablet dosage form","volume":"17","author":"Gohar","year":"2024","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.chroma.2026.466996_bib0007","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.3390\/pr12071530","article-title":"Optimization of sample preparation procedure for determination of fat-soluble vitamins in milk and infant food by HPLC technique","volume":"12","author":"Bo\u0161nir","year":"2024","journal-title":"Processes"},{"key":"10.1016\/j.chroma.2026.466996_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.jfca.2025.107573","article-title":"Simultaneous determination of vitamins A, D3 and E in milk and dairy foods by HPLC","volume":"143","author":"Yao","year":"2025","journal-title":"J. Food Compos. Anal."},{"key":"10.1016\/j.chroma.2026.466996_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2025.466021","article-title":"Supercritical fluid chromatography versus high-performance liquid chromatography \u2013 Performance, robustness and selectivity in the separation of vitamin A acetate and related substances","volume":"1754","author":"Legelli","year":"2025","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466996_bib0010","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1007\/s10068-025-01861-8","article-title":"Quantification of carotenoids in Korean fruits and vegetables using reverse-phase HPLC","volume":"34","author":"Jung","year":"2025","journal-title":"Food Sci. Biotechnol."},{"key":"10.1016\/j.chroma.2026.466996_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2020.461510","article-title":"Determination of vitamin D3 in daily oily supplements by a two-dimensional supercritical fluid chromatography-liquid chromatography-mass spectrometry system","volume":"1629","author":"Feng","year":"2020","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466996_bib0012","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.chroma.2017.12.012","article-title":"Simultaneous determination of 12 vitamin D compounds in human serum using online sample preparation and liquid chromatography-tandem mass spectrometry","volume":"1533","author":"Abu Kassim","year":"2018","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466996_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2023.463838","article-title":"Evaluation of the carotenoid and fat-soluble vitamin profile of industrial hemp inflorescence by liquid chromatography coupled to mass spectrometry and photodiode-array detection","volume":"1692","author":"Cerrato","year":"2023","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466996_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2021.462682","article-title":"Three-dimensional liquid chromatography with parallel second dimensions and quadruple parallel mass spectrometry for adult\/infant formula analysis","volume":"1661","author":"Byrdwell","year":"2022","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466996_bib0015","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.foodchem.2019.04.094","article-title":"Fast and simple method of simultaneous preservative determination in different processed foods by QuEChERS and HPLC-UV: method development, survey and estimate of daily intake","volume":"293","author":"de Oliveira Arias","year":"2019","journal-title":"Food Chem"},{"key":"10.1016\/j.chroma.2026.466996_bib0016","series-title":"Official Method 2012.10: Vitamin A and Vitamin E in Infant Formula and Adult\/Pediatric Nutritional Products \u2014 Normal-Phase LC Method, Official Methods of Analysis","year":"2012"},{"key":"10.1016\/j.chroma.2026.466996_bib0017","series-title":"Official Method 995.05: Vitamin D in Infant Formulas and Enteral Products - Liquid Chromatographic Method, Official Methods of Analysis","year":"2005"},{"key":"10.1016\/j.chroma.2026.466996_bib0018","series-title":"Infant Formula and Adult Nutritionals - Simultaneous Determination of Vitamin E and Vitamin A by Normal-Phase High-Performance Liquid Chromatography","year":"2015"},{"key":"10.1016\/j.chroma.2026.466996_bib0019","doi-asserted-by":"crossref","first-page":"223","DOI":"10.5740\/jaoacint.15-0094","article-title":"Determination of vitamin E and vitamin A in infant formula and adult nutritionals by normal-phase high-performance liquid chromatography: collaborative study, final Action 2012.10","volume":"99","author":"McMahon","year":"2016","journal-title":"J. AOAC Int."},{"key":"10.1016\/j.chroma.2026.466996_bib0020","doi-asserted-by":"crossref","first-page":"15681","DOI":"10.1021\/acs.jafc.1c06087","article-title":"Microencapsulated vitamin A palmitate degradation mechanism study to improve the product stability","volume":"69","author":"Xu","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.chroma.2026.466996_bib0021","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.foodres.2016.06.001","article-title":"Vitamin A degradation in triglycerides varying by their saturation levels","volume":"88","author":"Moccand","year":"2016","journal-title":"Food Res. Int."},{"key":"10.1016\/j.chroma.2026.466996_bib0022","doi-asserted-by":"crossref","DOI":"10.1002\/mas.21845","article-title":"Comprehensive and heart-cutting multidimensional liquid chromatography\u2013mass spectrometry and its applications in food analysis","author":"Ca\u00f1o-Carrillo","year":"2024","journal-title":"Mass Spectrom. Rev."},{"key":"10.1016\/j.chroma.2026.466996_bib0023","first-page":"1117","article-title":"Comprehensive two-dimensional liquid chromatography for the separation of food components: a review","volume":"10","author":"Cacciola","year":"2017","journal-title":"Food Anal. Methods"},{"key":"10.1016\/j.chroma.2026.466996_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.125486","article-title":"Combination of a solid phase extraction and a two-dimensional LC-UV method for the analysis of vitamin D3 and its isomers in olive oil","volume":"269","author":"Rinaldi","year":"2024","journal-title":"Talanta"},{"key":"10.1016\/j.chroma.2026.466996_bib0025","article-title":"Fast determination of vitamin A, vitamin D and vitamin E in food by online SPE combined with heart-cutting two-dimensional liquid chromatography","volume":"114","author":"Zhang","year":"2022","journal-title":"J. Food Compos. Anal."},{"key":"10.1016\/j.chroma.2026.466996_bib0026","first-page":"103","article-title":"Advanced analytical techniques for fat-soluble vitamin analysis","volume":"93","author":"Fanali","year":"2017","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.chroma.2026.466996_bib0027","first-page":"45","article-title":"Validation of analytical procedures: methodology ICH-Q2B","volume":"1","author":"Gajra","year":"2011","journal-title":"Int. J. Pharm. Innov."},{"key":"10.1016\/j.chroma.2026.466996_bib0028","series-title":"GB 5009.82-2016","year":"2016"},{"key":"10.1016\/j.chroma.2026.466996_bib0029","series-title":"GB 5009.83-2016","year":"2016"},{"key":"10.1016\/j.chroma.2026.466996_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.jfca.2022.105039","article-title":"Simultaneous determination of six vitamin A substances by multi-wavelength HPLC and application to different marine shellfishes","volume":"115","author":"Xing","year":"2023","journal-title":"J. Food Compos. Anal."},{"key":"10.1016\/j.chroma.2026.466996_bib0031","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1080\/10942912.2022.2151618","article-title":"Development of normal phase HPLC based method for the determination of retinyl palmitate in fortified edible oils","volume":"26","author":"Hasan","year":"2022","journal-title":"Int. J. Food Prop."},{"key":"10.1016\/j.chroma.2026.466996_bib0032","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jfca.2016.01.005","article-title":"Study on the elution order of carotenoids on endcapped C18 and C30 reverse silica stationary phases. A review of the database","volume":"47","author":"Turcsi","year":"2016","journal-title":"J. Food Compos. Anal."},{"key":"10.1016\/j.chroma.2026.466996_bib0033","doi-asserted-by":"crossref","first-page":"2856","DOI":"10.1080\/10408398.2019.1665494","article-title":"Suitability of stationary phase for LC analysis of biomolecules","volume":"60","author":"Saha","year":"2019","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.chroma.2026.466996_bib0034","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0378-4347(95)00494-7","article-title":"Liquid chromatographic determination of carotenoids in human serum usi ng an engineered C30 and a C18 stationary phase","volume":"678","author":"Sharpless","year":"1996","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.chroma.2026.466996_bib0036","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1021\/ac00042a016","article-title":"Separation and identification of carotenoids and their oxidation produ cts in the extracts of human plasma","volume":"64","author":"Khachik","year":"1992","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2026.466996_bib0037","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chroma.2011.12.025","article-title":"Analytical tools for the analysis of carotenoids in diverse materials","volume":"1224","author":"Rivera","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.466996_bib0038","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.jfca.2007.04.006","article-title":"Review: analysis of carotenoids in orange juice","volume":"20","author":"Mel\u00e9ndez-Mart\u00ednez","year":"2007","journal-title":"J. Food Compos. Anal."},{"key":"10.1016\/j.chroma.2026.466996_bib0039","series-title":"Carotenoids Carotenoid Apocarotenoid Anal","first-page":"423","article-title":"Chapter thirteen - carotenoid extraction and analysis from blood plasma\/serum","author":"Sholola","year":"2022"}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326003262?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326003262?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T01:17:06Z","timestamp":1778721426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967326003262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":38,"alternative-id":["S0021967326003262"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2026.466996","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Automated solid-phase extraction coupled with heart-cutting two\u2011dimensional liquid chromatography for simultaneous quantification of thirteen fat-soluble vitamins in foods for special medical purposes","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2026.466996","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"466996"}}