{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:58:54Z","timestamp":1790427534490,"version":"4.1.0"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.chroma.2026.467432","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T06:39:19Z","timestamp":1788417559000},"page":"467432","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Determination of nanoparticle density profiles using centrifugal field-flow fractionation coupled with multi-angle light scattering"],"prefix":"10.1016","volume":"1787","author":[{"given":"Soheyl","family":"Tadjiki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.chroma.2026.467432_bib0001","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1038\/s41578-021-00358-0","article-title":"Lipid nanoparticles for mRNA delivery","volume":"6","author":"Hou","year":"2021","journal-title":"Nat. Rev. Mater."},{"key":"10.1016\/j.chroma.2026.467432_bib0002","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.ejpb.2021.03.004","article-title":"Improved multidetector asymmetrical-flow field-flow fractionation method for particle sizing and concentration measurements of lipid-based nanocarriers for RNA delivery","volume":"163","author":"Mildner","year":"2021","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"4","key":"10.1016\/j.chroma.2026.467432_bib0003","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1107\/S1600577525003959","article-title":"AF4-to-SAXS: expanded characterization of nanoparticles and proteins at the P12 BioSAXS beamline","volume":"32","author":"Da Vela","year":"2025","journal-title":"J. Synchrotron. Radiat."},{"issue":"7","key":"10.1016\/j.chroma.2026.467432_bib0004","doi-asserted-by":"crossref","first-page":"5271","DOI":"10.1021\/acs.analchem.5c05911","article-title":"Advanced quality and comparability assessment of mRNA-loaded lipid nanoparticles: absolute size distribution profiles and structure from AF4-coupled light and X-ray scattering measurements","volume":"98","author":"Kolb","year":"2026","journal-title":"Anal. Chem."},{"issue":"3","key":"10.1016\/j.chroma.2026.467432_bib0005","doi-asserted-by":"crossref","first-page":"5068","DOI":"10.1021\/acsnano.0c10069","article-title":"Density matching multi-wavelength analytical ultracentrifugation to measure drug loading of lipid nanoparticle formulations","volume":"15","author":"Henrickson","year":"2021","journal-title":"ACS. Nano."},{"issue":"2","key":"10.1016\/j.chroma.2026.467432_bib0006","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.sbi.2008.02.001","article-title":"The structural biology of HIV assembly","volume":"18","author":"Ganser-Pornillos","year":"2008","journal-title":"Curr. Opin. Struct. Biol."},{"issue":"4","key":"10.1016\/j.chroma.2026.467432_bib0007","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.jmb.2011.04.021","article-title":"The molecular architecture of HIV","volume":"410","author":"Briggs","year":"2011","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.chroma.2026.467432_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.124571","article-title":"Physicochemical profiling of nanomedicines using centrifugal field flow fractionation","volume":"663","author":"Yamamoto","year":"2024","journal-title":"Int. J. Pharm."},{"issue":"15","key":"10.1016\/j.chroma.2026.467432_bib0009","doi-asserted-by":"crossref","first-page":"5976","DOI":"10.1021\/acs.analchem.4c00240","article-title":"Centrifugal field-flow fractionation enables detection of slight aggregation of nanoparticles that impacts their biomedical applications","volume":"96","author":"Tsuchiya","year":"2024","journal-title":"Anal. Chem."},{"issue":"28","key":"10.1016\/j.chroma.2026.467432_bib0010","doi-asserted-by":"crossref","first-page":"42623","DOI":"10.1021\/acsomega.6c02729","article-title":"Direct determination of apparent particle density and porosity in silica nanoparticles by size-resolved mass\u2013Volume analysis","volume":"11","author":"Tadjiki","year":"2026","journal-title":"ACS Omeg."},{"key":"10.1016\/j.chroma.2026.467432_bib0011","series-title":"Field-Flow Fractionation Handbook","author":"Schimpf","year":"2000"},{"issue":"5113","key":"10.1016\/j.chroma.2026.467432_bib0012","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1126\/science.8502990","article-title":"Field-flow fractionation: analysis of macromolecular, colloidal, and particulate materials","volume":"260","author":"Giddings","year":"1993","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.chroma.2026.467432_bib0013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0003-2670(93)80373-S","article-title":"Light scattering and the absolute characterization of macromolecules","volume":"272","author":"Wyatt","year":"1993","journal-title":"Anal. Chim. Acta"},{"issue":"17","key":"10.1016\/j.chroma.2026.467432_bib0014","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1021\/ac00144a007","article-title":"Power programmed field-flow fractionation: a new program form for improved uniformity of fractionating power","volume":"59","author":"Williams","year":"1987","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.chroma.2026.467432_bib0015","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1006\/jcis.1997.5215","article-title":"Submicrometer particle sizing by multiangle light scattering following fractionation","volume":"197","author":"Wyatt","year":"1998","journal-title":"J. Colloid. Interface Sci."},{"issue":"19","key":"10.1016\/j.chroma.2026.467432_bib0016","doi-asserted-by":"crossref","first-page":"10938","DOI":"10.1021\/acs.chemrev.5b00046","article-title":"New developments in liposomal drug delivery","volume":"115","author":"Pattni","year":"2015","journal-title":"Chem. Rev."},{"key":"10.1016\/j.chroma.2026.467432_bib0017","doi-asserted-by":"crossref","first-page":"286","DOI":"10.3389\/fphar.2015.00286","article-title":"Advances and challenges of liposome assisted drug delivery","volume":"6","author":"Sercombe","year":"2015","journal-title":"Front. Pharmacol."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326007582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326007582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:18:31Z","timestamp":1790425111000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967326007582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":17,"alternative-id":["S0021967326007582"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2026.467432","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Determination of nanoparticle density profiles using centrifugal field-flow fractionation coupled with multi-angle light scattering","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2026.467432","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"467432"}}