{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T12:52:52Z","timestamp":1791636772331,"version":"4.3.4"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.chroma.2026.467474","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:33:03Z","timestamp":1790033583000},"page":"467474","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Closed loop control and optimization in centrifugal partition chromatography"],"prefix":"10.1016","volume":"1788","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1165-8209","authenticated-orcid":false,"given":"Jan","family":"Hohlmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ediz","family":"Orta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1776-8801","authenticated-orcid":false,"given":"Niklas","family":"Hawighorst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Rhein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0186-9421","authenticated-orcid":false,"given":"Gerhard","family":"Schembecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chroma.2026.467474_bib0001","doi-asserted-by":"crossref","unstructured":"G. Szekely, D. Zhao (Eds.), Sustainable Separation engineering: Materials, Techniques and Process Development, John Wiley & Sons Ltd, Hoboken, NJ, 2022.","DOI":"10.1002\/9781119740117"},{"key":"10.1016\/j.chroma.2026.467474_bib0002","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3390\/separations11020056","article-title":"Spatially and temporally resolved analysis of bleeding in a centrifugal partition chromatography rotor","volume":"11","author":"Buthmann","year":"2024","journal-title":"Separations"},{"key":"10.1016\/j.chroma.2026.467474_bib0003","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3390\/separations11040098","article-title":"Counteracting bleeding in centrifugal partition chromatography: redosing of the stationary phase","volume":"11","author":"Buthmann","year":"2024","journal-title":"Separations"},{"key":"10.1016\/j.chroma.2026.467474_bib0004","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/separations11040111","article-title":"Optimizing chromatographic separation with redosing: effects on separation efficiency of a model system in centrifugal partition chromatography","volume":"11","author":"Buthmann","year":"2024","journal-title":"Separations"},{"key":"10.1016\/j.chroma.2026.467474_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2025.466580","article-title":"Phase retention control in preparative centrifugal partition chromatography","volume":"1767","author":"Hohlmann","year":"2026","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2026.467314","article-title":"Prediction of centrifugal partition chromatography separation performance via statistical design","volume":"1785","author":"Hohlmann","year":"2026","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0007","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.chroma.2019.06.024","article-title":"Modeling of closed-loop recycling dual-mode counter-current chromatography based on non-ideal recycling model","volume":"1603","author":"Kostanyan","year":"2019","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0008","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1039\/C8GC00179K","article-title":"Separation of phenolic acids by centrifugal partition chromatography","volume":"20","author":"Santos","year":"2018","journal-title":"Green Chem."},{"key":"10.1016\/j.chroma.2026.467474_bib0009","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1016\/j.jchromb.2009.05.040","article-title":"Multiple dual-mode centrifugal partition chromatography as an efficient method for the purification of a mycosporine from a crude methanolic extract of Lichina pygmaea","volume":"877","author":"Roullier","year":"2009","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2026.467474_bib0010","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.chroma.2006.05.069","article-title":"Multiple dual-mode centrifugal partition chromatography, a semi-continuous development mode for routine laboratory-scale purifications","volume":"1127","author":"Delannay","year":"2006","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0011","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.chroma.2017.03.039","article-title":"Trapping multiple dual mode centrifugal partition chromatography for the separation of intermediately-eluting components: operating parameter selection","volume":"1496","author":"Goll","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0012","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jchromb.2015.12.062","article-title":"Preparative separation of sesamin and sesamolin from defatted sesame meal via centrifugal partition chromatography with consecutive sample injection","volume":"1011","author":"Jeon","year":"2016","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.chroma.2026.467474_bib0013","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.chroma.2017.03.003","article-title":"Centrifugal partition chromatography in a biorefinery context: optimisation and scale-up of monosaccharide fractionation from hydrolysed sugar beet pulp","volume":"1497","author":"Ward","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0014","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/ceat.201100266","article-title":"Sequential centrifugal partition chromatography: a new continuous chromatographic technology","volume":"35","author":"Hopmann","year":"2012","journal-title":"Chem. Eng. Technol."},{"key":"10.1016\/j.chroma.2026.467474_bib0015","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.chroma.2013.01.116","article-title":"Study of the separation limits of continuous solid support free liquid-liquid chromatography: separation of capsaicin and dihydrocapsaicin by centrifugal partition chromatography","volume":"1284","author":"Goll","year":"2013","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0016","doi-asserted-by":"crossref","first-page":"3520","DOI":"10.1021\/acs.iecr.4c04759","article-title":"Sequential centrifugal partition chromatography separation under reduced product purity requirements: selection of the operating parameters","volume":"64","author":"Luca","year":"2025","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.chroma.2026.467474_bib0017","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.chroma.2015.07.020","article-title":"Scale-up in centrifugal partition chromatography: the \"free-space between peaks\" method","volume":"1409","author":"Bouju","year":"2015","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0018","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.chroma.2011.12.102","article-title":"Separation of a binary mixture by sequential centrifugal partition chromatography","volume":"1229","author":"Hopmann","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467474_bib0019","doi-asserted-by":"crossref","first-page":"2777","DOI":"10.1080\/10826070500225234","article-title":"G.U.E.S.S.\u2014a generally useful estimate of solvent systems for CCC","volume":"28","author":"Brent Friesen","year":"2005","journal-title":"J. Liq. Chromatogr. Relat. Technol."},{"key":"10.1016\/j.chroma.2026.467474_bib0020","doi-asserted-by":"crossref","unstructured":"H. Schmidt-Traub, M. Schulte, A. Seidel-Morgenstern (Eds.), Preparative Chromatography, 3rd ed., Wiley-VCH, Weinheim, 2020.","DOI":"10.1002\/9783527816347"}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326008009?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326008009?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T12:03:57Z","timestamp":1791633837000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967326008009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":20,"alternative-id":["S0021967326008009"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2026.467474","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Closed loop control and optimization in centrifugal partition chromatography","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2026.467474","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"467474"}}