{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T12:53:50Z","timestamp":1791636830911,"version":"4.3.4"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFC3712003"],"award-info":[{"award-number":["2024YFC3712003"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","award":["2025C02215"],"award-info":[{"award-number":["2025C02215"]}],"id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LR25B070001"],"award-info":[{"award-number":["LR25B070001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.chroma.2026.467488","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:14:10Z","timestamp":1790205250000},"page":"467488","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Robotic-assisted magnetic dispersive solid-phase extraction coupled with UHPLC\u2013MS\/MS for antibiotic analysis in aqueous matrices"],"prefix":"10.1016","volume":"1788","author":[{"given":"Guanghong","family":"Xiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daohui","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"49","key":"10.1016\/j.chroma.2026.467488_bib0001","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2411919121","article-title":"Global trends in antibiotic consumption during 2016\u20132023 and future projections through 2030 [J]","volume":"121","author":"Klein","year":"2024","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"1","key":"10.1016\/j.chroma.2026.467488_bib0002","first-page":"39","article-title":"A review of current status and analysis methods of antibiotic contamination in groundwater in China (2012-2021) [J]","volume":"42","author":"Ying","year":"2023","journal-title":"Rock Miner. Anal."},{"key":"10.1016\/j.chroma.2026.467488_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.ese.2025.100564","article-title":"Global antibiotic hotspots and risks: a one health assessment [J]","volume":"25","author":"Yan","year":"2025","journal-title":"Environ. Sci. Ecotechnol."},{"key":"10.1016\/j.chroma.2026.467488_bib0004","doi-asserted-by":"crossref","first-page":"e1880","DOI":"10.1016\/S2214-109X(25)00308-0","article-title":"Global antibiotic consumption and regional antimicrobial resistance, 2010\u201321: an analysis of pharmaceutical sales and antimicrobial resistance surveillance data [J]","volume":"13","author":"Wang","year":"2025","journal-title":"Lancet Glob. Health."},{"key":"10.1016\/j.chroma.2026.467488_bib0006","doi-asserted-by":"crossref","first-page":"16857","DOI":"10.1007\/s11356-015-4900-1","article-title":"Ultra-high performance liquid chromatography-electrospray tandem mass spectrometry for the analysis of antibiotic residues in environmental waters [J]","volume":"22","author":"Xue","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.chroma.2026.467488_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.173929","article-title":"Distribution pattern analysis of multiple antibiotics in the soil-rice system using a QuEChERS extraction method [J]","volume":"944","author":"Jin","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chroma.2026.467488_bib0008","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-04951-z","article-title":"Development SPE-LC-MS\/MS method for determination of WHO AWaRe Reserve antibiotics in hospital wastewater [J]","volume":"15","author":"Wilk","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.chroma.2026.467488_bib0009","doi-asserted-by":"crossref","first-page":"5204","DOI":"10.3390\/molecules25215204","article-title":"Sample preparation to determine pharmaceutical and personal care products in an all-water matrix: solid phase extraction [J]","volume":"25","author":"Sadutto","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.chroma.2026.467488_bib0010","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1080\/07373937.2011.645413","article-title":"Past, present, and future of solid phase extraction: a review [J]","volume":"42","author":"Buszewski","year":"2012","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.chroma.2026.467488_bib0011","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1007\/s44211-022-00190-8","article-title":"A review of the modern principles and applications of solid-phase extraction techniques in chromatographic analysis [J]","volume":"38","author":"Badawy","year":"2022","journal-title":"Anal. Sci."},{"key":"10.1016\/j.chroma.2026.467488_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.135312","article-title":"Analytical perspective and environmental remediation potentials of magnetic composite nanosorbents [J]","volume":"304","author":"Zhang","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.chroma.2026.467488_bib0013","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1080\/10643389.2020.1720493","article-title":"Application of solid-phase extraction based on magnetic nanoparticle adsorbents for the analysis of selected persistent organic pollutants in environmental water: a review of recent advances [J]","volume":"51","author":"Wu","year":"2021","journal-title":"Crit. Rev. Environ. Sci. Technol."},{"key":"10.1016\/j.chroma.2026.467488_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2023.109557","article-title":"Magnetic solid phase extraction based on metal organic framework for pharmaceutical analysis from food, environmental and biological media [J]","volume":"196","author":"Duo","year":"2024","journal-title":"Microchem. J."},{"key":"10.1016\/j.chroma.2026.467488_bib0015","article-title":"A nitrogen-rich functionalized magnetic COF-based MSPE method coupled with HPLC-MS\/MS for sulfonamide analysis in water samples [J]","volume":"218","author":"Li","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.chroma.2026.467488_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.110525","article-title":"Application of continuous magnetic solid phase extraction in the extraction of tetracycline antibiotics from honey samples [J]","volume":"201","author":"Rostami\u2013Javanroudi","year":"2024","journal-title":"Microchem. J."},{"key":"10.1016\/j.chroma.2026.467488_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2021.338957","article-title":"A reciprocating magnetic field assisted on-line solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry determination of trace tetracyclines in water [J]","volume":"1182","author":"Ri","year":"2021","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.chroma.2026.467488_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2019.460543","article-title":"Magnetic solid-phase extraction of sulfonamide antibiotics in water and animal-derived food samples using core-shell magnetite and molybdenum disulfide nanocomposite adsorbent[J]","volume":"1610","author":"Zhao","year":"2020","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467488_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2021.113988","article-title":"Fully automated peptide mapping multi-attribute method by liquid chromatography\u2013mass spectrometry with robotic liquid handling system [J]","volume":"198","author":"Qian","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2026.467488_bib0020","doi-asserted-by":"crossref","DOI":"10.1002\/jssc.70379","article-title":"Modification of a low-cost pipetting robot for nanoliter liquid handling and autosampling for liquid chromatography-mass spectrometry [J]","volume":"49","author":"Axtell","year":"2026","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2026.467488_bib0021","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.3390\/diagnostics16071093","article-title":"Collaborative robotic systems for pre-analytical processing of biological specimens in a medical laboratory [J]","volume":"16","author":"Komarov","year":"2026","journal-title":"Diagnostics"},{"key":"10.1016\/j.chroma.2026.467488_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2025.128529","article-title":"Online monitoring of odor compounds in drinking water sources by an integrated robotic sample preparation platform coupled with a gas chromatography-mass spectrometry system [J]","volume":"297","author":"Wu","year":"2026","journal-title":"Talanta"},{"key":"10.1016\/j.chroma.2026.467488_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2023.117171","article-title":"Modern automated sample preparation for the determination of organic compounds: a review on robotic and on-flow systems [J]","volume":"166","author":"Vargas Medina","year":"2023","journal-title":"TrAC, Trends Anal. Chem."},{"key":"10.1016\/j.chroma.2026.467488_bib0024","doi-asserted-by":"crossref","first-page":"12541","DOI":"10.1021\/acs.analchem.7b03767","article-title":"3D-printed microflow injection analysis platform for online magnetic nanoparticle sorptive extraction of antimicrobials in biological specimens as a front end to liquid chromatographic assays [J]","volume":"89","author":"Wang","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chroma.2026.467488_bib0025","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.aca.2020.03.033","article-title":"3D printed fluidic platform with in-situ covalently immobilized polymer monolithic column for automatic solid-phase extraction [J]","volume":"1111","author":"Carrasco-Correa","year":"2020","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.chroma.2026.467488_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2022.339874","article-title":"Renewable sorbent dispersive solid phase extraction automated by Lab-In-Syringe using magnetite-functionalized hydrophilic-lipophilic balanced sorbent coupled online to HPLC for determination of surface water contaminants [J]","volume":"1210","author":"Gemuh","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.chroma.2026.467488_bib0027","doi-asserted-by":"crossref","first-page":"8692","DOI":"10.1007\/s11356-017-8588-2","article-title":"An online SPE LC-MS\/MS method for the analysis of antibiotics in environmental water [J]","volume":"24","author":"Axel","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.chroma.2026.467488_bib0028","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3390\/toxics10030103","article-title":"A fully automated online SPE-LC-MS\/MS method for the determination of 10 pharmaceuticals in wastewater samples [J]","volume":"10","author":"Belay","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.chroma.2026.467488_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2022.463304","article-title":"Rapid and ultra-trace levels analysis of 33 antibiotics in water by on-line solid-phase extraction with ultra-performance liquid chromatography-tandem mass spectrometry [J]","volume":"1677","author":"Shen","year":"2022","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467488_bib0030","doi-asserted-by":"crossref","first-page":"16973","DOI":"10.1007\/s11356-021-15947-3","article-title":"Fully-automated SPE coupled to UHPLC-MS\/MS method for multiresidue analysis of 26 trace antibiotics in environmental waters: SPE optimization and method validation[J]","volume":"29","author":"Zheng","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.chroma.2026.467488_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2026.118394","article-title":"Rapid and ultra-trace analysis of weakly basic macrolide antibiotics and lincomycin in water by on-line solid-phase extraction (SPE) with ultra-performance liquid chromatography-tandem mass spectrometry [J]","volume":"226","author":"Shen","year":"2026","journal-title":"Microchem. J."},{"key":"10.1016\/j.chroma.2026.467488_bib0032","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.jpba.2013.05.006","article-title":"On-line solid phase extraction\u2013liquid chromatography, with emphasis on modern bioanalysis and miniaturized systems [J]","volume":"87","author":"Rogeberg","year":"2014","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2026.467488_bib0033","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s00216-012-6138-9","article-title":"Rapid narrow band elution for on-line SPE using a novel solvent plug injection technique [J]","volume":"404","author":"Gode","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.chroma.2026.467488_bib0034","series-title":"MagicFlux 1000 Automated Magnetic Solid-Phase Extrac Tion System","year":"2023"},{"key":"10.1016\/j.chroma.2026.467488_bib0035","series-title":"Auto M32 Automated Magnetic Solid-Phase Extraction System","year":"2026"},{"key":"10.1016\/j.chroma.2026.467488_bib0036","series-title":"KingFisher Flex system","year":"2026"},{"key":"10.1016\/j.chroma.2026.467488_bib0037","series-title":"EXTRACTMAX Automated Magnetic Bead Extraction System","year":"2026"},{"key":"10.1016\/j.chroma.2026.467488_bib0038","series-title":"Heidi-NA Automated Magnetic Bead Extraction System","year":"2026"},{"key":"10.1016\/j.chroma.2026.467488_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2026.467348","article-title":"Automated magnetic solid-phase extraction based on hydrophilic-lipophilic balanced materials for LC-MS\/MS determination of macrolides in pork [J]","volume":"1786","author":"Wang","year":"2026","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.chroma.2026.467488_bib0040","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.aca.2012.04.021","article-title":"Optimization of antibiotic analysis in water by solid-phase extraction and high performance liquid chromatography\u2013mass spectrometry\/mass spectrometry [J]","volume":"731","author":"Zhou","year":"2012","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.chroma.2026.467488_bib0041","doi-asserted-by":"crossref","first-page":"3587","DOI":"10.1039\/D5AN00482A","article-title":"Comparative performance evaluation of triple quadrupole tandem mass spectrometry and orbitrap high-resolution mass spectrometry for analysis of antibiotics in creek water impacted by CETP discharge [J]","volume":"150","author":"Ansari","year":"2025","journal-title":"Analyst"},{"key":"10.1016\/j.chroma.2026.467488_bib0042","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1007\/s00343-011-0225-1","article-title":"Detection of 36 antibiotics in coastal waters using high performance liquid chromatography-tandem mass spectrometry [J]","volume":"29","author":"Na","year":"2011","journal-title":"Chin. J. Oceanol. Limn."},{"key":"10.1016\/j.chroma.2026.467488_bib0043","doi-asserted-by":"crossref","first-page":"3117","DOI":"10.1002\/jssc.200800301","article-title":"Comparison of solid-phase sorbents for the determination of fluoroquinolone antibiotics in wastewater [J]","volume":"31","author":"Zorita","year":"2008","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.chroma.2026.467488_bib0044","doi-asserted-by":"crossref","first-page":"7754","DOI":"10.3390\/molecules27227754","article-title":"Interaction of antibiotics and humic substances: environmental consequences and remediation prospects [J]","volume":"27","author":"Kulikova","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.chroma.2026.467488_bib0045","article-title":"Advancing antibiotic detection in environmental waters: standardization of solid phase extraction procedures and development of certified reference materials [J]","volume":"15","author":"Wei","year":"2025","journal-title":"Sustain. Horiz."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326008149?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326008149?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T12:08:06Z","timestamp":1791634086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967326008149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":44,"alternative-id":["S0021967326008149"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2026.467488","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Robotic-assisted magnetic dispersive solid-phase extraction coupled with UHPLC\u2013MS\/MS for antibiotic analysis in aqueous matrices","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2026.467488","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"467488"}}