{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:34:12Z","timestamp":1793223252986,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100017691","name":"Guangxi Key Research and Development Program","doi-asserted-by":"publisher","award":["AB24010013"],"award-info":[{"award-number":["AB24010013"]}],"id":[{"id":"10.13039\/501100017691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography A"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.chroma.2026.467546","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T23:27:02Z","timestamp":1791934022000},"page":"467546","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A mini SPE purification method for the simultaneous determination of 15 mycotoxins in Ginkgo biloba leaves and their extracts by UHPLC-MS\/MS"],"prefix":"10.1016","volume":"1789","author":[{"given":"Congmin","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinjia","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihong","family":"Xuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoxia","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songxue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.chroma.2026.467546_bib0001","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.3390\/antiox13121528","article-title":"The detoxification effects of melatonin on aflatoxin-caused toxic effects and underlying molecular mechanisms","volume":"13","author":"Dai","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.chroma.2026.467546_bib0002","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.aninu.2023.09.003","article-title":"Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: a review","volume":"15","author":"Sun","year":"2023","journal-title":"Anim. Nutr."},{"issue":"2","key":"10.1016\/j.chroma.2026.467546_bib0003","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3390\/toxins15020085","article-title":"Type B trichothecenes in cereal grains and their products: recent advances on occurrence, toxicology, analysis and post-harvest decontamination strategies","volume":"15","author":"A","year":"2023","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.chroma.2026.467546_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.134542","article-title":"Development of a certified reference material for the accurate determination of type B trichothecenes in corn","volume":"404","author":"Gab-Allah","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2026.467546_bib0005","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.aninu.2022.08.016","article-title":"Zearalenone induces apoptosis and autophagy by regulating endoplasmic reticulum stress signalling in porcine trophectoderm cells","volume":"12","author":"Bai","year":"2023","journal-title":"Anim. Nutr."},{"key":"10.1016\/j.chroma.2026.467546_bib0006","doi-asserted-by":"crossref","unstructured":"U.o.G. Department of Poultry Science, Athens, GA 30602, USA., U.o.G. Department of Poultry Science, Athens, GA 30602, USA., zearalenone (ZEN) in livestock and poultry: dose, toxicokinetics, toxicity and estrogenicity, toxins 12(6) (2020). https:\/\/doi.org\/10.3390\/toxins12060377.","DOI":"10.3390\/toxins12060377"},{"issue":"20","key":"10.1016\/j.chroma.2026.467546_bib0007","doi-asserted-by":"crossref","first-page":"10374","DOI":"10.1039\/D2FO01545E","article-title":"Toxicity of zearalenone and its nutritional intervention by natural products","volume":"13","author":"Siyuan","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.chroma.2026.467546_bib0008","doi-asserted-by":"crossref","first-page":"10603","DOI":"10.1021\/acs.jafc.5c01735","article-title":"Effect of Fumonisin B1 and hydrolyzed FB1 exposure on intestinal and hepatic toxicity in BALB\/c mice","volume":"73","author":"Ye","year":"2025","journal-title":"J. Agric. Food Chem."},{"issue":"9","key":"10.1016\/j.chroma.2026.467546_bib0009","doi-asserted-by":"crossref","first-page":"5967","DOI":"10.1111\/1750-3841.17213","article-title":"Fumonisin B1 induces endoplasmic reticulum damage and inflammation by activating the NXR response and disrupting the normal CYP450 system, leading to liver damage in juvenile quail","volume":"89","author":"Zhu","year":"2024","journal-title":"J. Food Sci."},{"issue":"1","key":"10.1016\/j.chroma.2026.467546_bib0010","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s12550-016-0265-7","article-title":"Mycotoxins as human carcinogens\u2014The IARC Monographs classification","volume":"33","author":"Ostry","year":"2017","journal-title":"Mycotoxin. Res."},{"issue":"4","key":"10.1016\/j.chroma.2026.467546_bib0011","doi-asserted-by":"crossref","DOI":"10.1111\/jfs.12458","article-title":"Determination of multiple mycotoxin residues in Panax ginseng using simultaneous UPLC-ESI-MS\/MS","volume":"38","author":"Bi","year":"2018","journal-title":"J. Food Saf."},{"issue":"10","key":"10.1016\/j.chroma.2026.467546_bib0012","doi-asserted-by":"crossref","first-page":"690","DOI":"10.3390\/toxins14100690","article-title":"Multiple mycotoxin contamination in medicinal plants frequently sold in the free State province, South Africa detected using UPLC-ESI-MS\/MS","volume":"14","author":"Ndoro","year":"2022","journal-title":"Toxins. (Basel)"},{"issue":"10","key":"10.1016\/j.chroma.2026.467546_bib0013","first-page":"608","article-title":"Overview of aflatoxin B1 contamination in traditional Chinese medicine","volume":"15","author":"Zhao","year":"2018","journal-title":"Chin. J. Pharmacovigil."},{"issue":"19","key":"10.1016\/j.chroma.2026.467546_bib0014","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.3390\/foods11192983","article-title":"Development of a reliable ic-ELISA with a robust antimatrix interference capability based on QuEChERS technology for the rapid detection of zearalenone in edible and medical coix seeds and subsequent risk assessments","volume":"11","author":"Guan","year":"2022","journal-title":"Foods"},{"issue":"6","key":"10.1016\/j.chroma.2026.467546_bib0015","doi-asserted-by":"crossref","first-page":"5066","DOI":"10.1007\/s11694-022-01584-y","article-title":"Ochratoxin A in chamomile, black and green tea and human health risk assessment in Iranian population","volume":"16","author":"Esmi","year":"2022","journal-title":"J. Food Meas. Charact."},{"issue":"2\u20133","key":"10.1016\/j.chroma.2026.467546_bib0016","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.foodchem.2012.11.066","article-title":"Simultaneous determination of aflatoxin B 1 and ochratoxin A in licorice roots and fritillary bulbs by solid-phase extraction coupled with high-performance liquid chromatography\u2013tandem mass spectrometry","volume":"138","author":"Wang","year":"2013","journal-title":"Food Chem."},{"issue":"4","key":"10.1016\/j.chroma.2026.467546_bib0017","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1007\/s10068-017-0117-z","article-title":"Ginseng fermented by mycotoxin non-producing Aspergillus niger: ginsenoside analysis and anti-proliferative effects","volume":"26","author":"Zhipeng","year":"2017","journal-title":"Food Sci. Biotechnol."},{"key":"10.1016\/j.chroma.2026.467546_bib0018","unstructured":"Pharmacopoeia of People's Republic of China, China Medical Science Press, Bei Jing, 2025."},{"issue":"3","key":"10.1016\/j.chroma.2026.467546_bib0019","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/BF02950942","article-title":"Experimental study on effect of folium ginkgo biloba in treating pulmonary interstitial fibrosis in rats","volume":"6","author":"Jian","year":"2000","journal-title":"Chin. J. Integr. Tradit. West. Med."},{"issue":"6","key":"10.1016\/j.chroma.2026.467546_bib0020","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1002\/ptr.2335","article-title":"Ginkgo biloba extract improves coronary artery circulation in patients with coronary artery disease: contribution of plasma nitric oxide and endothelin-1","volume":"22","author":"Wu","year":"2008","journal-title":"Phytother. Res."},{"issue":"2","key":"10.1016\/j.chroma.2026.467546_bib0021","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.brainresbull.2011.11.002","article-title":"Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats","volume":"87","author":"Zhang","year":"2012","journal-title":"Brain Res. Bull."},{"issue":"1","key":"10.1016\/j.chroma.2026.467546_bib0022","first-page":"1","article-title":"The clinical efficacy of ginkgo biloba leaf preparation on ischemic stroke: a systematic review and meta-analysis","volume":"2021","author":"Zhao","year":"2021","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"10.1016\/j.chroma.2026.467546_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113704","article-title":"Advances in the chemical constituents and chemical analysis of ginkgo biloba leaf, extract, and phytopharmaceuticals","volume":"193","author":"Liu","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.chroma.2026.467546_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156565","article-title":"Ginkgo biloba leaf extract EGb 761\u00ae for the treatment of various diseases: overview of systematic reviews","volume":"141","author":"Pfuhlmann","year":"2025","journal-title":"Phytomedicine"},{"issue":"9","key":"10.1016\/j.chroma.2026.467546_bib0025","doi-asserted-by":"crossref","DOI":"10.1111\/cns.14914","article-title":"Investigating the effects of Ginkgo biloba leaf extract on cognitive function in Alzheimer's disease","volume":"30","author":"Zhu","year":"2024","journal-title":"CNS. Neurosci. Ther."},{"key":"10.1016\/j.chroma.2026.467546_bib0026","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.foodchem.2017.11.040","article-title":"Determination of multiple mycotoxins in feedstuffs by combined use of UPLC\u2013MS\/MS and UPLC\u2013QTOF\u2013MS","volume":"267","author":"Romera","year":"2018","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2026.467546_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2025.146356","article-title":"Determination of 22 mycotoxins in wheat grains cultivated in two Moroccan climatic areas by UHPLC-MS\/MS","volume":"495","author":"Zinedine","year":"2025","journal-title":"Food Chem."},{"key":"10.1016\/j.chroma.2026.467546_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.jfca.2025.107836","article-title":"Accurate determination of aflatoxins in coffee by isotope dilution\u2013ultrahigh-performance liquid chromatography\u2013tandem mass spectrometry","volume":"145","author":"Lijalem","year":"2025","journal-title":"J. Food Compos. Anal."},{"key":"10.1016\/j.chroma.2026.467546_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2025.115756","article-title":"Analysis of multiple mycotoxins in Galangal and assessment of its essential oil against Aspergillus flavus","volume":"218","author":"Guo","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.chroma.2026.467546_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2023.341573","article-title":"Mobile phase and column chemistry selection for high sensitivity non-targeted LC\/ESI\/HRMS screening of water","volume":"1274","author":"Souihi","year":"2023","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.chroma.2026.467546_bib0034","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.aca.2018.02.055","article-title":"Mass spectrometric recommendations for Quan\/Qual analysis using liquid-chromatography coupled to quadrupole time-of-flight mass spectrometry","volume":"1020","author":"Dubbelman","year":"2018","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.chroma.2026.467546_bib0035","article-title":"A review on recent developments and applications of green sorbents-based solid phase extraction techniques","volume":"6","author":"Ma","year":"2023","journal-title":"Adv. Sample Prep."},{"key":"10.1016\/j.chroma.2026.467546_bib0036","first-page":"2025","article-title":"Extraction, content determination, component analysis, and pharmacological action of Hedysari flavonoids: a review of research progress","volume":"16","author":"Huang","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.chroma.2026.467546_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.137502","article-title":"An integrated screening method for paralytic shellfish toxins and their analogues based on fragmentation characteristics using an orbitrap-based ultrahigh-performance liquid chromatography-high-resolution mass spectrometry","volume":"434","author":"Liang","year":"2024","journal-title":"Food Chem."}],"container-title":["Journal of Chromatography A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326008721?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021967326008721?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:06:27Z","timestamp":1793221587000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021967326008721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":34,"alternative-id":["S0021967326008721"],"URL":"https:\/\/doi.org\/10.1016\/j.chroma.2026.467546","relation":{},"ISSN":["0021-9673"],"issn-type":[{"value":"0021-9673","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A mini SPE purification method for the simultaneous determination of 15 mycotoxins in Ginkgo biloba leaves and their extracts by UHPLC-MS\/MS","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography A","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chroma.2026.467546","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"467546"}}