{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:56:40Z","timestamp":1777885000423,"version":"3.51.4"},"reference-count":24,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1016\/j.cimid.2005.01.001","type":"journal-article","created":{"date-parts":[[2005,2,17]],"date-time":"2005-02-17T23:09:20Z","timestamp":1108681760000},"page":"167-176","source":"Crossref","is-referenced-by-count":17,"title":["Production and purification of ovine anti-tetanus antibody"],"prefix":"10.1016","volume":"28","author":[{"given":"El-Rashdy M.","family":"Redwan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Khalil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeinab Z.","family":"EL-Dardiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cimid.2005.01.001_bib1","series-title":"Tetanus","author":"Adams","year":"1969"},{"key":"10.1016\/j.cimid.2005.01.001_bib2","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/0011-5029(91)90008-Y","article-title":"Tetanus: pathophysiology, management, and prophylaxis","volume":"37","author":"Bleck","year":"1991","journal-title":"Dis Mon"},{"key":"10.1016\/j.cimid.2005.01.001_bib3","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/S0140-6736(71)91659-X","article-title":"Double-blind trial of equine antitoxin and human immune globulin in tetanus neonatourm","volume":"1","author":"McCracken","year":"1971","journal-title":"Lancet"},{"key":"10.1016\/j.cimid.2005.01.001_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-3101(24)00173-7","article-title":"Human gamma globulin as therapeutic agents","volume":"35","author":"Steihm","year":"1988","journal-title":"Adv Pediatr"},{"key":"10.1016\/j.cimid.2005.01.001_bib5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1136\/bmj.292.6512.17","article-title":"Protection, prevention and mechanism of early (anaphylactic) antivenom reactions in victims of snake bites","volume":"292","author":"Malasit","year":"1986","journal-title":"Br Med J"},{"key":"10.1016\/j.cimid.2005.01.001_bib6","doi-asserted-by":"crossref","first-page":"291","DOI":"10.4269\/ajtmh.1997.56.291","article-title":"First clinical experiences with a new ovine Fab Echis ocellatus snake bite antivenom in Nigeria: Randomized comparative trial with institute Pasteur serum (IPSER) and Africa antivenom","volume":"56","author":"Meyer","year":"1997","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.cimid.2005.01.001_bib7","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0168-1656(98)00182-5","article-title":"Feasibility studies of large scale production of human anti-tetanus toxoid monoclonal antibodies","volume":"67","author":"Martial-Gros","year":"1999","journal-title":"J Biotechnol"},{"key":"10.1016\/j.cimid.2005.01.001_bib8","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1007\/BF00151713","article-title":"Establishment of stable mouse\/human hybrid cell lines producing large amounts of antitetanus human monoclonal antibodies with high neutralizing activity","volume":"6","author":"Kamei","year":"1990","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.cimid.2005.01.001_bib9","first-page":"89","article-title":"In vitro immunization for the production of antibodies to tetanus toxin and toxoid.2.antibody production in lymphocyte cultures","volume":"33","author":"Jahns","year":"1987","journal-title":"Allergy Immunol (Leipz)"},{"key":"10.1016\/j.cimid.2005.01.001_bib10","first-page":"306","article-title":"Protective human hyberidoma antibody tetanus toxin","volume":"70","author":"Gigliatti","year":"1982","journal-title":"J Clin Invest"},{"key":"10.1016\/j.cimid.2005.01.001_bib11","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0958-1669(98)80014-1","article-title":"Recombinant antibody fragments","volume":"9","author":"Hudson","year":"1998","journal-title":"Curr Opinion Biotechnol"},{"key":"10.1016\/j.cimid.2005.01.001_bib12","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/S0735-1097(10)80170-6","article-title":"Digoxin immune Fab therapy in the management of digitialis intoxication:safety and efficacy. Results of an observational surveillance study","volume":"17","author":"Hickey","year":"1991","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cimid.2005.01.001_bib13","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3233\/HAB-2002-111-211","article-title":"Prevalence of tetanus immunity in the Egyptian population","volume":"11","author":"Redwan","year":"2002","journal-title":"Human Antibody"},{"key":"10.1016\/j.cimid.2005.01.001_bib14","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head bacteriophage T4","volume":"227","author":"Laemmli","year":"1971","journal-title":"Nature"},{"key":"10.1016\/j.cimid.2005.01.001_bib15","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0041-0101(94)90107-4","article-title":"A new antivenom to treat eastern coral snake (Micrurus fulvius fulvius) envenoming","volume":"32","author":"Rawat","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.cimid.2005.01.001_bib16","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagents","volume":"193","author":"Lowery","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1016\/j.cimid.2005.01.001_bib17","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/0041-0101(92)90384-H","article-title":"An affinity purified ovine antivenom for the treatment of vipera berus envenoming","volume":"30","author":"Smith","year":"1992","journal-title":"Toxicon"},{"key":"10.1016\/j.cimid.2005.01.001_bib18","series-title":"Antibody production, essential techniques series","author":"Delves","year":"1997"},{"key":"10.1016\/j.cimid.2005.01.001_bib19","article-title":"Toxins and antitoxins","author":"Butler","year":"1972"},{"key":"10.1016\/j.cimid.2005.01.001_bib20","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0022-1759(90)90458-8","article-title":"Purification of human immunoglobulin by sequential precipitation with carprylic acid and ammonium sulfate","volume":"128","author":"Perosa","year":"1990","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.cimid.2005.01.001_bib21","series-title":"Monoclonal antibodies, a practical approach","author":"Shepherd","year":"2000"},{"key":"10.1016\/j.cimid.2005.01.001_bib22","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0041-0101(02)00393-8","article-title":"Report of a WHO workshop on the standardization and control of antivenoms","volume":"41","author":"Theakston","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.cimid.2005.01.001_bib23","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/0041-0101(94)90341-7","article-title":"Snake antivenoms from hyperimmunized horses: comparison of the antivenom activity and biological properties of their whole IgG and F(ab')2 fragments","volume":"32","author":"Morias","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.cimid.2005.01.001_bib24","first-page":"3087","article-title":"Adder bites","volume":"165","author":"Lauridsen","year":"2003","journal-title":"Ugeskr Laeger"}],"container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957105000020?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957105000020?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T16:14:16Z","timestamp":1706026456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147957105000020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S0147957105000020"],"URL":"https:\/\/doi.org\/10.1016\/j.cimid.2005.01.001","relation":{},"ISSN":["0147-9571"],"issn-type":[{"value":"0147-9571","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}