{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T01:57:55Z","timestamp":1762999075783},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.cimid.2014.12.002","type":"journal-article","created":{"date-parts":[[2015,1,17]],"date-time":"2015-01-17T23:16:58Z","timestamp":1421536618000},"page":"1-8","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Undiagnosed leptospirosis cases in na\u00efve and vaccinated dogs: Properties of a serological test based on a synthetic peptide derived from Hap1\/LipL32 (residues 154\u2013178)"],"prefix":"10.1016","volume":"39","author":[{"given":"Genevi\u00e8ve","family":"Andre-Fontaine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florence","family":"Aviat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Lou","family":"Marie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benoit","family":"Chatrenet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cimid.2014.12.002_bib0155","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0021-9975(97)80079-5","article-title":"Chronic hepatitis associated with field strain Leptospira infection in a vaccinated colony of laboratory Beagle dogs","volume":"117","author":"Adamus","year":"1997","journal-title":"Comp Pathol"},{"key":"10.1016\/j.cimid.2014.12.002_bib0160","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.vetmic.2006.04.005","article-title":"Canine leptospirosis\u2014do we have a problem?","volume":"117","author":"Andr\u00e9-Fontaine","year":"2006","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.cimid.2014.12.002_bib0165","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1136\/vr.101333","article-title":"Diagnosis algorithm for Leptospirosis in dogs: disease and vaccination effects on the serological results","volume":"172","author":"Andr\u00e9-Fontaine","year":"2013","journal-title":"Vet Rec"},{"key":"10.1016\/j.cimid.2014.12.002_bib0170","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.femsle.2005.01.007","article-title":"Polymerase chain reaction assay specific for pathogenic Leptospira based on the gene hap1 encoding the hemolysis-associated protein-1","volume":"243","author":"Branger","year":"2005","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.cimid.2014.12.002_bib0175","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.vetmic.2004.07.018","article-title":"Recombinant LipL32 antigen-based single serum dilution ELISA for detection of canine Leptospirosis","volume":"103","author":"Dey","year":"2004","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.cimid.2014.12.002_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1939-1676.2010.0654.x","article-title":"2010 ACVIM small animal consensus statement on leptospirosis: diagnosis, epidemiology, treatment, and prevention","volume":"25","author":"Sykes","year":"2011","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.cimid.2014.12.002_bib0185","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0264-410X(00)00129-8","article-title":"Evidence of cross-protection within Leptospira interrogans in an experimental model","volume":"19","author":"Sonrier","year":"2001","journal-title":"Vaccine"},{"key":"10.1016\/j.cimid.2014.12.002_bib0190","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.femsre.2003.10.004","article-title":"Outer membrane proteins of pathogenic spirochetes lipoproteins and pathogenesis","volume":"28","author":"Cullen","year":"2004","journal-title":"FEMS Microbiol Rev"},{"key":"10.1016\/j.cimid.2014.12.002_bib0195","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0882-4010(91)90014-2","article-title":"Characterization of outer membrane and secreted proteins of Leptospira interrogans serovar Pomona","volume":"10","author":"Zuerner","year":"1991","journal-title":"Microb Pathog"},{"key":"10.1016\/j.cimid.2014.12.002_bib0200","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1128\/IAI.68.4.2276-2285.2000","article-title":"The Leptospiral major outer membrane protein LipL32 is a Lipoprotein expressed during mammalian infection","volume":"68","author":"Haake","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.cimid.2014.12.002_bib0205","doi-asserted-by":"crossref","first-page":"4936","DOI":"10.1128\/IAI.70.9.4936-4945.2002","article-title":"Characterization of the Leptospiral outer membrane and description of three novel Leptospiral membrane proteins","volume":"70","author":"Haake","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.cimid.2014.12.002_bib0210","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1128\/IAI.71.5.2414-2421.2003","article-title":"LipL 21 is a novel surface exposed lipoprotein of pathogenic Leptospira","volume":"41","author":"Cullen","year":"2003","journal-title":"Infect Immun"},{"key":"10.1016\/j.cimid.2014.12.002_bib0215","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0378-1135(94)90138-4","article-title":"Recognition of Leptospira interrogans antigens by vaccinated or infected dogs","volume":"41","author":"Gitton","year":"1995","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.cimid.2014.12.002_bib0220","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1128\/IAI.01639-07","article-title":"LipL32, the major Leptospiral Lipoprotein: the C terminus is the primary immunogenic domain and mediates interaction with collagen IV and plasma fibronectin","volume":"76","author":"Hauk","year":"2008","journal-title":"Infect Immun"},{"key":"10.1016\/j.cimid.2014.12.002_bib0225","doi-asserted-by":"crossref","first-page":"3174","DOI":"10.1128\/IAI.63.8.3174-3181.1995","article-title":"The rare outer membrane protein OmpL1 of pathogenic Leptospira species is a heat-modifiable porin","volume":"63","author":"Shang","year":"1995","journal-title":"Infect Immun"},{"key":"10.1016\/j.cimid.2014.12.002_bib0230","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0378-1119(00)00293-6","article-title":"Identification and partial characterization of a novel hemolysin from Leptospira interrogans serovar lai","volume":"254","author":"Lee","year":"2000","journal-title":"Gene"},{"key":"10.1016\/j.cimid.2014.12.002_bib0235","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1136\/vr.160.6.186","article-title":"Recombinant antigen-based dipstick ELISA for the diagnosis of leptospirosis in dogs","volume":"160","author":"Dey","year":"2007","journal-title":"Vet Rec"},{"key":"10.1016\/j.cimid.2014.12.002_bib0240","first-page":"3174","article-title":"C6 peptide ELISA test in the serodiagnosis of Lyme borreliosis in Sweden","volume":"63","author":"Tjerberg","year":"1995","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.cimid.2014.12.002_bib0245","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1136\/vr.153.6.165","article-title":"Comparison of the efficacy of three commercial bacterins used to prevent canine leptospirosis","volume":"153","author":"Andr\u00e9-Fontaine","year":"2003","journal-title":"Vet Rec"},{"issue":"5","key":"10.1016\/j.cimid.2014.12.002_bib0250","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.cimid.2009.01.001","article-title":"Synthetic peptide issued from Hap1\/LipL32 for new early diagnosis of human leptospirosis","volume":"33","author":"Aviat","year":"2010","journal-title":"Comp Immunol Microbiol Infect Dis"},{"key":"10.1016\/j.cimid.2014.12.002_bib0255","first-page":"65","article-title":"Un cas de leptospirose canine au Tchad","volume":"286","author":"Roqueplo","year":"2008","journal-title":"Point V\u00e9t"},{"key":"10.1016\/j.cimid.2014.12.002_bib0260","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.vetmic.2012.11.005","article-title":"The lipoprotein LipL32, an enigma of leptospiral biology","volume":"162","author":"Murray","year":"2013","journal-title":"Vet Mic"},{"key":"10.1016\/j.cimid.2014.12.002_bib0265","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.cimid.2008.05.004","article-title":"Leptospira exposure in the human environment in France: a survey in feral rodents and fresh water","volume":"32","author":"Aviat","year":"2009","journal-title":"Comp Immunol Microbiol Infect Dis"},{"key":"10.1016\/j.cimid.2014.12.002_bib0270","doi-asserted-by":"crossref","first-page":"e6071","DOI":"10.1371\/journal.pone.0006071","article-title":"A comprehensive approach to identification of surface-exposed, outer membrane-spanning proteins of Leptospira interrogans","volume":"4","author":"Pinne","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cimid.2014.12.002_bib0275","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1128\/CVI.05622-11","article-title":"Analysis of multiple Leptospira vaccine proteomes and identification of LipL32 as a biomarker for potency","volume":"19","author":"Humphryes","year":"2012","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.cimid.2014.12.002_bib0280","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1128\/IAI.01643-07","article-title":"LipL32 is an extracellular matrix-interacting protein of Leptospira spp and Pseudoalteromonas tunicate","volume":"76","author":"Hoke","year":"2008","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.cimid.2014.12.002_bib0285","doi-asserted-by":"crossref","first-page":"e51025","DOI":"10.1371\/journal.pone.0051025","article-title":"LipL32 Is a Subsurface Lipoprotein of Leptospira interrogans: presentation of new data and reevaluation of previous studies","volume":"8","author":"Pinne","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cimid.2014.12.002_bib0290","series-title":"J.B.C. March 13\u2014M112418699","article-title":"Essential calcium binding cluster of Leptospira LipL32 for inflammatory responses through the Toll-like receptor 2 pathway","author":"Lo","year":"2013"},{"key":"10.1016\/j.cimid.2014.12.002_bib0295","first-page":"591","article-title":"Leptospirosis: a Toll road from B lymphocytes","volume":"33","author":"Werts","year":"2010","journal-title":"Chang Gung Med J"},{"key":"10.1016\/j.cimid.2014.12.002_bib0300","first-page":"11","article-title":"Leptospira and inflammation","author":"Goncalves-de-Albuquerque","year":"2012","journal-title":"Mediat Inflam"}],"container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957114000745?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957114000745?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T02:39:37Z","timestamp":1598668777000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147957114000745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":30,"alternative-id":["S0147957114000745"],"URL":"https:\/\/doi.org\/10.1016\/j.cimid.2014.12.002","relation":{},"ISSN":["0147-9571"],"issn-type":[{"value":"0147-9571","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Undiagnosed leptospirosis cases in na\u00efve and vaccinated dogs: Properties of a serological test based on a synthetic peptide derived from Hap1\/LipL32 (residues 154\u2013178)","name":"articletitle","label":"Article Title"},{"value":"Comparative Immunology, Microbiology and Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cimid.2014.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}