{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T21:33:51Z","timestamp":1768340031061,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Science and Technology of People\u2019s Republic of China","award":["2017YFD0500104"],"award-info":[{"award-number":["2017YFD0500104"]}]},{"name":"Ministry of Science and Technology of People\u2019s Republic of China","award":["2016YFD0500904"],"award-info":[{"award-number":["2016YFD0500904"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.cimid.2019.01.002","type":"journal-article","created":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T11:10:27Z","timestamp":1547032227000},"page":"44-50","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Disruption of blood-brain barrier by an Escherichia coli isolated from canine septicemia and meningoencephalitis"],"prefix":"10.1016","volume":"63","author":[{"given":"Xin","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zecai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoran","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junying","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingqi","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cimid.2019.01.002_bib0005","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nrmicro2298","article-title":"The population genetics of commensal Escherichia coli","volume":"8","author":"Tenaillon","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.cimid.2019.01.002_bib0010","doi-asserted-by":"crossref","first-page":"E238","DOI":"10.1111\/1469-0691.12128","article-title":"IncI1 plasmids associated with the spread of CMY-2, CTX-M-1 and SHV-12 in Escherichia coli of animal and human origin","volume":"19","author":"Accogli","year":"2013","journal-title":"Clin. Microbiol. Inf."},{"key":"10.1016\/j.cimid.2019.01.002_bib0015","first-page":"140","article-title":"The epidemiology, management, and outcomes of bacterial meningitis in infants","author":"Ouchenir","year":"2017","journal-title":"Pediatrics"},{"key":"10.1016\/j.cimid.2019.01.002_bib0020","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.4269\/ajtmh.17-0066","article-title":"Molecular and phenotypic characterization of Diarrheagenic escherichia coli strains isolated from bacteremic children","volume":"97","author":"Riveros","year":"2017","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.cimid.2019.01.002_bib0025","doi-asserted-by":"crossref","first-page":"19184","DOI":"10.7448\/IAS.17.1.19184","article-title":"Meningitis in HIV-positive patients in sub-Saharan Africa: a review","volume":"17","author":"Veltman","year":"2014","journal-title":"J. Int. AIDS Soc."},{"key":"10.1016\/j.cimid.2019.01.002_bib0030","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1128\/AEM.02962-14","article-title":"Novel variant serotype of streptococcus suis isolated from piglets with meningitis","volume":"81","author":"Pan","year":"2015","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.cimid.2019.01.002_bib0035","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.vetmic.2014.04.019","article-title":"Advances in vaccination against avian pathogenic Escherichia coli respiratory disease: potentials and limitations","volume":"172","author":"Ghunaim","year":"2014","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.cimid.2019.01.002_bib0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017921","article-title":"Bacillus anthracis protease InhA increases blood-brain barrier permeability and contributes to cerebral hemorrhages","volume":"6","author":"Mukherjee","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.cimid.2019.01.002_bib0045","first-page":"11","article-title":"MiR-429 Regulated by Endothelial Monocyte Activating Polypeptide-II (EMAP-II) Influences Blood-Tumor Barrier Permeability by Inhibiting the Expressions of ZO-1, Occludin and Claudin-5","author":"Chen","year":"2018","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.cimid.2019.01.002_bib0050","first-page":"556","article-title":"TNFalpha disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice. Brain, behavior","volume":"69","author":"Cheng","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.cimid.2019.01.002_bib0055","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/480739","article-title":"Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain","author":"Ramesh","year":"2013","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.cimid.2019.01.002_bib0060","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.cyto.2011.10.016","article-title":"TNF-alpha induced NF kappa B signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells","volume":"57","author":"Aslam","year":"2012","journal-title":"Cytokine"},{"key":"10.1016\/j.cimid.2019.01.002_bib0065","first-page":"3459","article-title":"Mechanisms of oxidative stress effects of the NADPH oxidase-ROS-NF-kappaB transduction pathway and VPO1 on patients with chronic obstructive pulmonary disease combined with pulmonary hypertension","volume":"21","author":"Zhuan","year":"2017","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.cimid.2019.01.002_bib0070","doi-asserted-by":"crossref","first-page":"558","DOI":"10.3389\/fimmu.2017.00558","article-title":"In vivo and in vitro study on the efficacy of Terpinen-4-ol in dextran sulfate sodium-induced mice experimental colitis","volume":"8","author":"Zhang","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cimid.2019.01.002_bib0075","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.brainresbull.2011.09.021","article-title":"Polydatin modulates inflammation by decreasing NF-kappaB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood-brain barrier permeability for its neuroprotective effect in pMCAO rat brain","volume":"87","author":"Ji","year":"2012","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.cimid.2019.01.002_bib0080","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.brainres.2012.03.065","article-title":"Neuroprotection of early and short-time applying berberine in the acute phase of cerebral ischemia: up-regulated pAkt, pGSK and pCREB, down-regulated NF-kappaB expression, ameliorated BBB permeability","volume":"1459","author":"Zhang","year":"2012","journal-title":"Brain Res."},{"issue":"19","key":"10.1016\/j.cimid.2019.01.002_bib0085","first-page":"1749","article-title":"Pseudorabies virus variant in Bartha-K61-Vaccinated pigs, China","volume":"2013","author":"An","year":"2012","journal-title":"Emerg Infect Dis."},{"key":"10.1016\/j.cimid.2019.01.002_bib0090","article-title":"Identification of a novel splicing form of amelogenin gene in a reptile, Ctenosaura similis","volume":"7","author":"Wang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cimid.2019.01.002_bib0095","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1124\/pr.57.2.4","article-title":"The blood-brain barrier\/neurovascular unit in health and disease","volume":"57","author":"Hawkins","year":"2005","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.cimid.2019.01.002_bib0100","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1080\/21505594.2015.1091914","article-title":"Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis","volume":"6","author":"Krishnan","year":"2015","journal-title":"Virulence"},{"key":"10.1016\/j.cimid.2019.01.002_bib0105","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.meegid.2015.02.013","article-title":"Isolation, identification, and pathogenicity of O142 avian pathogenic Escherichia coli causing black proventriculus and septicemia in broiler breeders","volume":"32","author":"Wang","year":"2015","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.cimid.2019.01.002_bib0110","doi-asserted-by":"crossref","DOI":"10.1007\/s00203-018-1482-6","article-title":"Bacteriocinogenic properties of Escherichia coli P2C isolated from pig gastrointestinal tract: purification and characterization of microcin V","author":"Boubezari","year":"2018","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.cimid.2019.01.002_bib0115","first-page":"12","article-title":"Evaluation of Escherichia coli isolates from healthy chickens to determine their potential risk to poultry and human health","author":"Stromberg","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.cimid.2019.01.002_bib0120","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1038\/aps.2014.99","article-title":"Exogenous carbon monoxide suppresses Escherichia coli vitality and improves survival in an Escherichia coli-induced murine sepsis model","volume":"35","author":"Shen","year":"2014","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.cimid.2019.01.002_bib0125","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1177\/0271678X16630991","article-title":"In vitro models of the blood-brain barrier: an overview of commonly used brain endothelial cell culture models and guidelines for their use","volume":"36","author":"Helms","year":"2016","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.cimid.2019.01.002_bib0130","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.neuroscience.2012.08.043","article-title":"Ischemia-reperfusion impairs blood-brain barrier function and alters tight junction protein expression in the ovine fetus","volume":"226","author":"Chen","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.cimid.2019.01.002_bib0135","first-page":"3213","article-title":"In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha","volume":"119","author":"Connolly","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cimid.2019.01.002_bib0140","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1161\/ATVBAHA.110.213850","article-title":"Mechanisms of resolution of inflammation a focus on cardiovascular disease","volume":"31","author":"Maskrey","year":"2011","journal-title":"Arterioscl Throm Vas."},{"key":"10.1016\/j.cimid.2019.01.002_bib0145","first-page":"1","article-title":"Macrophage cytokines: involvement in immunity and infectious diseases","volume":"5","author":"Duque","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cimid.2019.01.002_bib0150","doi-asserted-by":"crossref","first-page":"6853","DOI":"10.1038\/sj.onc.1203239","article-title":"Activators and target genes of Rel\/NF-kappa B transcription factors","volume":"18","author":"Pahl","year":"1999","journal-title":"Oncogene"}],"container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957119300062?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957119300062?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,5]],"date-time":"2019-04-05T20:31:57Z","timestamp":1554496317000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147957119300062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":30,"alternative-id":["S0147957119300062"],"URL":"https:\/\/doi.org\/10.1016\/j.cimid.2019.01.002","relation":{},"ISSN":["0147-9571"],"issn-type":[{"value":"0147-9571","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Disruption of blood-brain barrier by an Escherichia coli isolated from canine septicemia and meningoencephalitis","name":"articletitle","label":"Article Title"},{"value":"Comparative Immunology, Microbiology and Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cimid.2019.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}