{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:06:08Z","timestamp":1787763968449,"version":"build-2784847793"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100013153","name":"Shantou Science and Technology Project","doi-asserted-by":"publisher","award":["180709174010328"],"award-info":[{"award-number":["180709174010328"]}],"id":[{"id":"10.13039\/501100013153","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["AID-OAA-A-14-00102"],"award-info":[{"award-number":["AID-OAA-A-14-00102"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.cimid.2019.03.004","type":"journal-article","created":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T02:33:34Z","timestamp":1552012414000},"page":"153-158","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Etiology and characteristics of community-acquired pneumonia in an influenza epidemic period"],"prefix":"10.1016","volume":"64","author":[{"given":"Chun","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanzhu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazhen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changwen","family":"Ke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyang","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cimid.2019.03.004_bib0005","doi-asserted-by":"crossref","first-page":"885","DOI":"10.3109\/00365548.2012.700120","article-title":"Swedish guidelines on the management of community-acquired pneumonia in immunocompetent adults\u2014Swedish Society of Infectious Diseases 2012","volume":"44","author":"Spindler","year":"2012","journal-title":"Scand. J. Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0010","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1093\/cid\/civ1214","article-title":"Comprehensive molecular testing for respiratory pathogens in community-acquired pneumonia","volume":"62","author":"Gadsby","year":"2016","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0015","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1128\/JCM.06186-11","article-title":"Comparison of the Luminex xTAG RVP Fast assay and the Idaho Technology FilmArray RP assay for detection of respiratory viruses in pediatric patients at a cancer hospital","volume":"50","author":"Babady","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.cimid.2019.03.004_bib0020","series-title":"Influenza (seasonal) Fact Sheet No 211. 2009","author":"WHO","year":"2009"},{"key":"10.1016\/j.cimid.2019.03.004_bib0025","doi-asserted-by":"crossref","first-page":"26076","DOI":"10.1038\/srep26076","article-title":"Metabolomics investigation reveals metabolite mediators associated with acute lung injury and repair in a murine model of influenza pneumonia","volume":"6","author":"Cui","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cimid.2019.03.004_bib0030","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1186\/s12879-016-1642-8","article-title":"Relationship of influenza virus infection to associated infections in children who present with influenza-like symptoms","volume":"16","author":"Norowitz","year":"2016","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0035","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1146\/annurev.pathmechdis.3.121806.154316","article-title":"The pathology of influenza virus infections","volume":"3","author":"Taubenberger","year":"2008","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.cimid.2019.03.004_bib0040","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/1469-0691.12093","article-title":"Do specific virus-bacteria pairings drive clinical outcomes of pneumonia?","volume":"19","author":"McCullers","year":"2013","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.cimid.2019.03.004_bib0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003057","article-title":"Viral and bacterial interactions in the upper respiratory tract","volume":"9","author":"Bosch","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.cimid.2019.03.004_bib0050","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1093\/infdis\/jit190","article-title":"Bacterial complications of respiratory tract viral illness: a comprehensive evaluation","volume":"208","author":"Falsey","year":"2013","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0055","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/nrmicro3231","article-title":"The co-pathogenesis of influenza viruses with bacteria in the lung","volume":"12","author":"McCullers","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.cimid.2019.03.004_bib0060","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/cc8893","article-title":"Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications","volume":"14","author":"van der Sluijs","year":"2010","journal-title":"Crit Care"},{"key":"10.1016\/j.cimid.2019.03.004_bib0065","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3005982","article-title":"Identifying the interaction between influenza and pneumococcal pneumonia using incidence data","volume":"5","author":"Shrestha","year":"2013","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.cimid.2019.03.004_bib0070","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1007\/s00705-014-2035-1","article-title":"Viral etiology of influenza-like illnesses in Huizhou, China, from 2011 to 2013","volume":"159","author":"Ju","year":"2014","journal-title":"Arch. Virol."},{"key":"10.1016\/j.cimid.2019.03.004_bib0075","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1002\/jmv.24480","article-title":"Viral etiology of medically attended influenza-like illnesses in children less than five years old in Suzhou, China, 2011\u20132014","volume":"88","author":"Wang","year":"2016","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.cimid.2019.03.004_bib0080","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/jmv.22247","article-title":"The epidemiology and etiology of influenza-like illness in Chinese children from 2008 to 2010","volume":"84","author":"Peng","year":"2012","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.cimid.2019.03.004_bib0085","article-title":"Etiology and clinical characteristics of influenza-like illness (ILI) in outpatients in Beijing, June 2010 to May 2011","volume":"7","author":"Yang","year":"2012","journal-title":"PLoS One"},{"issue":"Suppl 6","key":"10.1016\/j.cimid.2019.03.004_bib0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1469-0691.2011.03602.x","article-title":"Guidelines for the management of adult lower respiratory tract infections\u2014summary","volume":"17","author":"Woodhead","year":"2011","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.cimid.2019.03.004_bib0095","doi-asserted-by":"crossref","first-page":"4083","DOI":"10.1128\/JCM.05010-11","article-title":"Comparison of the FilmArray Respiratory Panel and Prodesse real-time PCR assays for detection of respiratory pathogens","volume":"49","author":"Loeffelholz","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.cimid.2019.03.004_bib0100","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1001\/archpedi.156.12.1230","article-title":"The effect of rapid respiratory viral diagnostic testing on antibiotic use in a children\u2019s hospital","volume":"156","author":"Byington","year":"2002","journal-title":"Arch. Pediatr. Adolesc. Med."},{"key":"10.1016\/j.cimid.2019.03.004_bib0105","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1016\/S0140-6736(03)15021-0","article-title":"Community-acquired pneumonia","volume":"362","author":"File","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.cimid.2019.03.004_bib0110","first-page":"353","article-title":"Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies","volume":"83","author":"Cherian","year":"2005","journal-title":"Bull. World Health Organ."},{"issue":"Suppl 2","key":"10.1016\/j.cimid.2019.03.004_bib0115","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1086\/511159","article-title":"Infectious Diseases Society of America\/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults","volume":"44","author":"Mandell","year":"2007","journal-title":"Clin. Infect. Dis."},{"issue":"Suppl 4","key":"10.1016\/j.cimid.2019.03.004_bib0120","doi-asserted-by":"crossref","first-page":"S296","DOI":"10.1093\/cid\/cir045","article-title":"Diagnostic tests for agents of community-acquired pneumonia","volume":"52","author":"Bartlett","year":"2011","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0125","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/QCO.0000000000000255","article-title":"Microbiome, biofilms, and pneumonia in the ICU","volume":"29","author":"Pirrone","year":"2016","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0130","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1086\/648678","article-title":"Etiology of community-acquired pneumonia: increased microbiological yield with new diagnostic methods","volume":"50","author":"Johansson","year":"2010","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0135","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1136\/thoraxjnl-2013-203551","article-title":"Community-acquired pneumonia in Chile: the clinical relevance in the detection of viruses and atypical bacteria","volume":"68","author":"Luchsinger","year":"2013","journal-title":"Thorax"},{"key":"10.1016\/j.cimid.2019.03.004_bib0140","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s12879-015-0803-5","article-title":"Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway","volume":"15","author":"Holter","year":"2015","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0145","first-page":"1071","article-title":"Bacterial coinfections in lung tissue specimens from fatal cases of 2009 pandemic influenza A (H1N1) - United States, May\u2013August 2009","volume":"58","author":"Centers for Disease","year":"2009","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.cimid.2019.03.004_bib0150","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1086\/319746","article-title":"Microbial etiology of community-acquired pneumonia in the adult population of 4 municipalities in eastern Finland","volume":"32","author":"Jokinen","year":"2001","journal-title":"Clin. Infect. Dis."},{"issue":"Suppl 4","key":"10.1016\/j.cimid.2019.03.004_bib0155","first-page":"IV1","article-title":"British thoracic society standards of care C. BTS guidelines for the management of community acquired pneumonia in adults","volume":"56","year":"2001","journal-title":"Thorax"},{"key":"10.1016\/j.cimid.2019.03.004_bib0160","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1136\/thoraxjnl-2015-206933","article-title":"Respiratory viruses associated with community-acquired pneumonia in children: matched case-control study","volume":"70","author":"Rhedin","year":"2015","journal-title":"Thorax"},{"key":"10.1016\/j.cimid.2019.03.004_bib0165","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.medmal.2015.06.002","article-title":"Community-acquired Acinetobacter baumannii pneumonia","volume":"45","author":"Bachoumas","year":"2015","journal-title":"Med. Mal. Infect."},{"key":"10.1016\/j.cimid.2019.03.004_bib0170","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/2049-632X.12125","article-title":"Acinetobacter baumannii: evolution of a global pathogen","volume":"71","author":"Antunes","year":"2014","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0175","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1186\/s12879-017-2471-0","article-title":"Pneumonia caused by extensive drug-resistant Acinetobacter baumannii among hospitalized patients: genetic relationships, risk factors and mortality","volume":"17","author":"Li","year":"2017","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.cimid.2019.03.004_bib0180","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jmii.2014.06.011","article-title":"Comparison of pneumonia- and non-pneumonia-related Acinetobacter baumannii bacteremia: impact on empiric therapy and antibiotic resistance","volume":"48","author":"Teng","year":"2015","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"10.1016\/j.cimid.2019.03.004_bib0185","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1086\/503053","article-title":"Pneumococcal coinfection with human metapneumovirus","volume":"193","author":"Madhi","year":"2006","journal-title":"J. Infect. Dis."},{"issue":"Suppl 1","key":"10.1016\/j.cimid.2019.03.004_bib0190","first-page":"i1","article-title":"British thoracic society standards of care C. British thoracic society guidelines for the management of community acquired pneumonia in childhood","volume":"57","year":"2002","journal-title":"Thorax"},{"key":"10.1016\/j.cimid.2019.03.004_bib0195","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/S0140-6736(10)61459-6","article-title":"Viral pneumonia","volume":"377","author":"Ruuskanen","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.cimid.2019.03.004_bib0200","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jcv.2014.08.023","article-title":"The use of a multiplex real-time PCR assay for diagnosing acute respiratory viral infections in children attending an emergency unit","volume":"61","author":"Mengelle","year":"2014","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.cimid.2019.03.004_bib0205","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1097\/CCM.0b013e3182416f23","article-title":"Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States","volume":"40","author":"Rice","year":"2012","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.cimid.2019.03.004_bib0210","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jinf.2009.12.012","article-title":"Predictors and outcomes of respiratory failure among hospitalized pneumonia patients with 2009 H1N1 influenza in Taiwan","volume":"60","author":"Chien","year":"2010","journal-title":"J. Infect."},{"key":"10.1016\/j.cimid.2019.03.004_bib0215","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/CCM.0b013e318194b097","article-title":"Early blood glucose control and mortality in critically ill patients in Australia","volume":"37","author":"Bagshaw","year":"2009","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.cimid.2019.03.004_bib0220","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.hrtlng.2016.02.006","article-title":"Adult human metapneumonovirus (hMPV) pneumonia mimicking Legionnaire\u2019s disease","volume":"45","author":"Cunha","year":"2016","journal-title":"Heart Lung"},{"key":"10.1016\/j.cimid.2019.03.004_bib0225","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S2213-2600(16)00046-1","article-title":"Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study","volume":"4","author":"Davenport","year":"2016","journal-title":"Lancet Respir. Med."}],"container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957119300499?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957119300499?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T06:44:24Z","timestamp":1758955464000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147957119300499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":45,"alternative-id":["S0147957119300499"],"URL":"https:\/\/doi.org\/10.1016\/j.cimid.2019.03.004","relation":{},"ISSN":["0147-9571"],"issn-type":[{"value":"0147-9571","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Etiology and characteristics of community-acquired pneumonia in an influenza epidemic period","name":"articletitle","label":"Article Title"},{"value":"Comparative Immunology, Microbiology and Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cimid.2019.03.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}