{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:04:00Z","timestamp":1759017840513,"version":"3.44.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.cimid.2019.101340","type":"journal-article","created":{"date-parts":[[2020,1,25]],"date-time":"2020-01-25T11:23:00Z","timestamp":1579951380000},"page":"101340","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Q fever in Greece: Findings of a 13 years surveillance study"],"prefix":"10.1016","volume":"69","author":[{"given":"Iosif","family":"Vranakis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Kokkini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanouil","family":"Yachnakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yannis","family":"Tselentis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimosthenis","family":"Chochlakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Psaroulaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cimid.2019.101340_bib0005","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/978-94-007-4315-1_11","article-title":"Axenic growth of Coxiella burnetii","volume":"984","author":"Omsland","year":"2012","journal-title":"Adv. Exp. Med. Biol."},{"issue":"4","key":"10.1016\/j.cimid.2019.101340_bib0010","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1128\/CMR.12.4.518","article-title":"Q fever","volume":"12","author":"Maurin","year":"1999","journal-title":"Clin. Microbiol. Rev."},{"issue":"3","key":"10.1016\/j.cimid.2019.101340_bib0015","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1051\/vetres:2005010","article-title":"Is Q fever an emerging or re-emerging zoonosis?","volume":"36","author":"Arricau-Bouvery","year":"2005","journal-title":"Vet. Res."},{"issue":"7","key":"10.1016\/j.cimid.2019.101340_bib0020","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.3201\/eid1007.030724","article-title":"Wind in November, Q fever in December","volume":"10","author":"Tissot-Dupont","year":"2004","journal-title":"Emerg Infect Dis"},{"issue":"3","key":"10.1016\/j.cimid.2019.101340_bib0025","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.idc.2008.03.002","article-title":"Q fever","volume":"22","author":"Tissot-Dupont","year":"2008","journal-title":"Infect. Dis. Clin. North Am."},{"issue":"5963","key":"10.1016\/j.cimid.2019.101340_bib0030","first-page":"266","article-title":"Infectious diseases. Questions abound in Q-fever explosion in the Netherlands","volume":"327","author":"Enserink","year":"2010","journal-title":"Science"},{"issue":"3-4","key":"10.1016\/j.cimid.2019.101340_bib0035","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.vetmic.2009.07.016","article-title":"Q Fever","volume":"140","author":"Angelakis","year":"2010","journal-title":"Vet Microbiol"},{"issue":"6","key":"10.1016\/j.cimid.2019.101340_bib0040","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1001\/archinte.162.6.693","article-title":"Neurological involvement in acute Q fever: a report of 29 cases and review of the literature","volume":"162","author":"Bernit","year":"2002","journal-title":"Arch. Intern. Med."},{"issue":"4","key":"10.1016\/j.cimid.2019.101340_bib0045","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1161\/01.CIR.53.4.680","article-title":"Q fever endocarditis in Queensland","volume":"53","author":"Wilson","year":"1976","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.cimid.2019.101340_bib0050","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1136\/hrt.43.6.695","article-title":"Chronic q fever endocarditis","volume":"43","author":"Varma","year":"1980","journal-title":"Br. Heart J."},{"issue":"3","key":"10.1016\/j.cimid.2019.101340_bib0055","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1128\/AAC.35.3.533","article-title":"Comparison of different antibiotic regimens for therapy of 32 cases of Q fever endocarditis","volume":"35","author":"Levy","year":"1991","journal-title":"Antimicrob. Agents Chemother."},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0060","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1001\/archinte.159.2.167","article-title":"Treatment of Q fever endocarditis: comparison of 2 regimens containing doxycycline and ofloxacin or hydroxychloroquine","volume":"159","author":"Raoult","year":"1999","journal-title":"Arch. Intern. Med."},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0065","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.medmal.2008.07.008","article-title":"Q fever: current diagnosis and treatment options","volume":"39","author":"Million","year":"2009","journal-title":"Med. Mal. Infect."},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0070","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jinf.2013.10.010","article-title":"Reduction in incidence of Q fever endocarditis: 27 years of experience of a national reference center","volume":"68","author":"Edouard","year":"2014","journal-title":"J. Infect."},{"issue":"RR-03","key":"10.1016\/j.cimid.2019.101340_bib0075","first-page":"1","article-title":"Diagnosis and management of Q fever--united States, 2013: recommendations from CDC and the Q Fever Working Group","volume":"62","author":"Anderson","year":"2013","journal-title":"MMWR Recomm. Rep."},{"issue":"1","key":"10.1016\/j.cimid.2019.101340_bib0080","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1128\/CMR.00045-16","article-title":"From q fever to Coxiella burnetii infection: a paradigm change","volume":"30","author":"Eldin","year":"2017","journal-title":"Clin. Microbiol. Rev."},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0085","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1128\/cdli.1.2.189-196.1994","article-title":"Q fever serology: cutoff determination for microimmunofluorescence","volume":"1","author":"Dupont","year":"1994","journal-title":"Clin. Diagn. Lab. Immunol."},{"year":"2019","series-title":"Population and Social Conditions","author":"Authority","key":"10.1016\/j.cimid.2019.101340_bib0090"},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0095","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.cimid.2011.11.006","article-title":"Serological survey of Q fever in Crete, southern Greece","volume":"35","author":"Vranakis","year":"2012","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"issue":"11","key":"10.1016\/j.cimid.2019.101340_bib0100","doi-asserted-by":"crossref","first-page":"e977","DOI":"10.1016\/j.ijid.2013.04.010","article-title":"Antibody kinetics in serological indication of chronic Q fever: the Greek experience","volume":"17","author":"Kokkini","year":"2013","journal-title":"Int. J. Infect. Dis."},{"issue":"8","key":"10.1016\/j.cimid.2019.101340_bib0105","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1128\/JCM.36.8.2210-2213.1998","article-title":"Direct identification of Coxiella burnetii plasmids in human sera by nested PCR","volume":"36","author":"Zhang","year":"1998","journal-title":"J. Clin. Microbiol."},{"issue":"1","key":"10.1016\/j.cimid.2019.101340_bib0110","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1128\/JCM.36.1.77-80.1998","article-title":"Clinical evaluation of a new PCR assay for detection of Coxiella burnetii in human serum samples","volume":"36","author":"Zhang","year":"1998","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.cimid.2019.101340_bib0115","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1196\/annals.1374.111","article-title":"Evaluation of a real-time PCR assay to detect Coxiella burnetii","volume":"1078","author":"Klee","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.cimid.2019.101340_bib0120","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-2180-6-2","article-title":"Highly sensitive real-time PCR for specific detection and quantification of Coxiella burnetii","volume":"6","author":"Klee","year":"2006","journal-title":"BMC Microbiol."},{"issue":"1","key":"10.1016\/j.cimid.2019.101340_bib0125","doi-asserted-by":"crossref","first-page":"86","DOI":"10.4269\/ajtmh.2002.66.86","article-title":"Isolation of Coxiella burnetii by a centrifugation shell-vial assay from ticks collected in Cyprus: detection by nested polymerase chain reaction (PCR) and by PCR-restriction fragment length polymorphism analyses","volume":"66","author":"Spyridaki","year":"2002","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"7","key":"10.1016\/j.cimid.2019.101340_bib0130","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1128\/JCM.36.7.2063-2067.1998","article-title":"Q fever in the Greek island of Crete: detection, isolation, and molecular identification of eight strains of Coxiella burnetii from clinical samples","volume":"36","author":"Spyridaki","year":"1998","journal-title":"J. Clin. Microbiol."},{"issue":"Suppl 2","key":"10.1016\/j.cimid.2019.101340_bib0135","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1469-0691.2008.02159.x","article-title":"The serological prevalence of Coxiella burnetii antibodies in sheep and goats in northern Greece","volume":"15","author":"Pape","year":"2009","journal-title":"Clin. Microbiol. Infect."},{"issue":"4","key":"10.1016\/j.cimid.2019.101340_bib0140","doi-asserted-by":"crossref","first-page":"702","DOI":"10.26444\/aaem\/80706","article-title":"Serological prevalence of Coxiella burnetii in dairy goats and ewes diagnosed with adverse pregnancy outcomes in Greece","volume":"24","author":"Filioussis","year":"2017","journal-title":"Ann. Agric. Environ. Med."},{"issue":"3","key":"10.1016\/j.cimid.2019.101340_bib0145","doi-asserted-by":"crossref","first-page":"350","DOI":"10.3201\/eid1703.100882","article-title":"Q fever in France, 1985\u20132009","volume":"17","author":"Frankel","year":"2011","journal-title":"Emerg Infect Dis"},{"issue":"1","key":"10.1016\/j.cimid.2019.101340_bib0150","first-page":"1","article-title":"Australia\u2019s notifiable disease status, 2010: annual report of the National Notifiable Diseases Surveillance System","volume":"36","author":"Milton","year":"2012","journal-title":"Commun. Dis. Intell. Q. Rep."},{"issue":"1","key":"10.1016\/j.cimid.2019.101340_bib0155","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.phrp.2012.12.006","article-title":"Epidemiological characteristics of serologically confirmed q Fever cases in South Korea, 2006-2011","volume":"4","author":"Kwak","year":"2013","journal-title":"Osong Public Health Res. Perspect."},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0160","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/00005792-200003000-00005","article-title":"Q fever 1985-1998. Clinical and epidemiologic features of 1,383 infections","volume":"79","author":"Raoult","year":"2000","journal-title":"Medicine (Baltimore)"},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0165","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/00365540701558722","article-title":"Acute Q fever: an emerging and endemic disease in southern Taiwan","volume":"40","author":"Lai","year":"2008","journal-title":"Scand. J. Infect. Dis."},{"issue":"1-2","key":"10.1016\/j.cimid.2019.101340_bib0170","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1071\/NB11037","article-title":"EpiReview: notifications of Q fever in NSW, 2001-2010","volume":"23","author":"Lowbridge","year":"2012","journal-title":"N. S. W. Public Health Bull."},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0175","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1086\/380798","article-title":"Effect of sex on Coxiella burnetii infection: protective role of 17beta-estradiol","volume":"189","author":"Leone","year":"2004","journal-title":"J. Infect. Dis."},{"issue":"1","key":"10.1016\/j.cimid.2019.101340_bib0180","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1017\/S0950268811000227","article-title":"Assessing Q fever in a representative sample from the United States population: identification of a potential occupational hazard","volume":"140","author":"Walsh","year":"2012","journal-title":"Epidemiol. Infect."},{"issue":"1","key":"10.1016\/j.cimid.2019.101340_bib0185","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/oxfordjournals.aje.a009920","article-title":"Hyperendemic focus of Q fever related to sheep and wind","volume":"150","author":"Tissot-Dupont","year":"1999","journal-title":"Am. J. Epidemiol."},{"issue":"15","key":"10.1016\/j.cimid.2019.101340_bib0190","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.1017\/S0950268814003926","article-title":"Q fever infection in dairy cattle herds: increased risk with high wind speed and low precipitation","volume":"143","author":"Nusinovici","year":"2015","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.cimid.2019.101340_bib0195","first-page":"1","article-title":"Q fever infection in dairy cattle herds: increased risk with high wind speed and low precipitation","author":"Nusinovici","year":"2015","journal-title":"Epidemiol. Infect."},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0200","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1017\/S0950268814001083","article-title":"A windy day in a sheep saleyard: an outbreak of Q fever in rural South Australia","volume":"143","author":"O\u2019Connor","year":"2015","journal-title":"Epidemiol. Infect."},{"issue":"5","key":"10.1016\/j.cimid.2019.101340_bib0205","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1093\/clinids\/20.5.1311","article-title":"Q fever in the Greek Island of Crete: epidemiologic, clinical, and therapeutic data from 98 cases","volume":"20","author":"Tselentis","year":"1995","journal-title":"Clin. Infect. Dis."},{"issue":"3","key":"10.1016\/j.cimid.2019.101340_bib0210","article-title":"\"Clinical and epidemiological features of hospitalized acute Q fever cases from Split-Dalmatia County (Croatia), 1985-2002","volume":"12","author":"Luksic","year":"2006","journal-title":"Med. Sci. Monit."},{"issue":"2","key":"10.1016\/j.cimid.2019.101340_bib0215","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1093\/ije\/16.2.282","article-title":"An important outbreak of human Q fever in a Swiss Alpine valley","volume":"16","author":"Dupuis","year":"1987","journal-title":"Int. J. Epidemiol."},{"issue":"1","key":"10.1016\/j.cimid.2019.101340_bib0220","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1093\/clinids\/10.1.198","article-title":"Q fever in Spain: acute and chronic cases, 1981-1985","volume":"10","author":"Tellez","year":"1988","journal-title":"Rev. Infect. Dis."},{"issue":"3","key":"10.1016\/j.cimid.2019.101340_bib0225","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1183\/09031936.93.02030263","article-title":"Q fever pneumonia: a review of 164 community-acquired cases in the Basque country","volume":"2","author":"Sobradillo","year":"1989","journal-title":"Eur. Respir. J."},{"issue":"4","key":"10.1016\/j.cimid.2019.101340_bib0230","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1086\/520452","article-title":"Acute Q fever in adult patients: report on 63 sporadic cases in an urban area","volume":"29","author":"Domingo","year":"1999","journal-title":"Clin. Infect. Dis."},{"issue":"10","key":"10.1016\/j.cimid.2019.101340_bib0235","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1086\/515401","article-title":"From acute Q fever to endocarditis: serological follow-up strategy","volume":"44","author":"Landais","year":"2007","journal-title":"Clin. Infect. Dis."},{"issue":"3","key":"10.1016\/j.cimid.2019.101340_bib0240","doi-asserted-by":"crossref","first-page":"20058","DOI":"10.2807\/ese.17.03.20058-en","article-title":"Relation between Q fever notifications and Coxiella burnetii infections during the 2009 outbreak in the Netherlands","volume":"17","author":"van der Hoek","year":"2012","journal-title":"Euro Surveill."}],"container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957119301377?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957119301377?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T06:45:39Z","timestamp":1758955539000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147957119301377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":48,"alternative-id":["S0147957119301377"],"URL":"https:\/\/doi.org\/10.1016\/j.cimid.2019.101340","relation":{},"ISSN":["0147-9571"],"issn-type":[{"type":"print","value":"0147-9571"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Q fever in Greece: Findings of a 13 years surveillance study","name":"articletitle","label":"Article Title"},{"value":"Comparative Immunology, Microbiology and Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cimid.2019.101340","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101340"}}