{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:43:06Z","timestamp":1790088186039,"version":"4.0.1"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010203","name":"Agriculture Research System of China","doi-asserted-by":"publisher","award":["CARS-43-C-1"],"award-info":[{"award-number":["CARS-43-C-1"]}],"id":[{"id":"10.13039\/501100010203","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.cimid.2022.101889","type":"journal-article","created":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T20:59:31Z","timestamp":1665435571000},"page":"101889","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Experimental pathogenicity and comparative genome analysis of high- and low-virulence strains of rabbit-origin Pasteurella multocida"],"prefix":"10.1016","volume":"90-91","author":[{"given":"Rulong","family":"Qiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houjun","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhua","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizhong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyu","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cimid.2022.101889_bib1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1128\/CMR.00024-13","article-title":"Pasteurella multocida: from zoonosis to cellular microbiology","volume":"26","author":"Wilson","year":"2013","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.cimid.2022.101889_bib2","first-page":"1","article-title":"Pasteurella multocida: diseases and pathogenesis","volume":"361","author":"Wilkie","year":"2012","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.cimid.2022.101889_bib3","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1128\/JCM.39.3.924-929.2001","article-title":"Genetic organization of Pasteurella multocida cap Loci and development of a multiplex capsular PCR typing system","volume":"39","author":"Townsend","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2006.00442.x","article-title":"Pasteurella multocida pathogenesis: 125 years after Pasteur","volume":"265","author":"Harper","year":"2006","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.cimid.2022.101889_bib5","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/1471-2180-13-106","article-title":"Comparative genome analysis of an avirulent and two virulent strains of avian Pasteurella multocida reveals candidate genes involved in fitness and pathogenicity","volume":"13","author":"Johnson","year":"2013","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib6","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.vetmic.2016.11.028","article-title":"Experimental pathogenicity and complete genome characterization of a pig origin Pasteurella multocida serogroup F isolate HN07","volume":"198","author":"Peng","year":"2007","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130296","article-title":"Comparative genomic analysis of asian haemorrhagic septicaemia-associated strains of Pasteurella multocida Identifies More than 90 Haemorrhagic Septicaemia-Specific genes","volume":"10","author":"Moustafa","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.cimid.2022.101889_bib8","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.vetmic.2007.06.008","article-title":"Experimental study of pathogenicity of Pasteurella multocida serogroup F in rabbits","volume":"126","author":"Jaglic","year":"2008","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib9","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/j.1439-0450.2004.00807.x","article-title":"Identification of Pasteurella multocida Serogroup F isolates in rabbits","volume":"51","author":"Jaglic","year":"2004","journal-title":"J. Vet. Med B Infect. Dis. Vet. Public Health"},{"key":"10.1016\/j.cimid.2022.101889_bib10","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jcpa.2015.06.005","article-title":"Experimental study of the Pathogenicity of Pasteurella multocida Capsular Type B in rabbits","volume":"153","author":"Katoch","year":"2015","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.cimid.2022.101889_bib11","first-page":"23","article-title":"Pathogenomics of Pasteurella multocida","volume":"361","author":"Boyce","year":"2012","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.cimid.2022.101889_bib12","doi-asserted-by":"crossref","first-page":"3460","DOI":"10.1073\/pnas.051634598","article-title":"Complete genomic sequence of Pasteurella multocida, Pm70","volume":"98","author":"May","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cimid.2022.101889_bib13","doi-asserted-by":"crossref","DOI":"10.1128\/MRA.00681-19","article-title":"Genome sequences of 17 Pasteurella multocida strains involved in cases of rabbit Pasteurellosis","volume":"8","author":"Kempf","year":"2019","journal-title":"Microbiol. Resour. Announc"},{"key":"10.1016\/j.cimid.2022.101889_bib14","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.gene.2016.01.041","article-title":"Genomic characterization of Pasteurella multocida HB01, a serotype A bovine isolate from China","volume":"581","author":"Peng","year":"2016","journal-title":"Gene"},{"key":"10.1016\/j.cimid.2022.101889_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetmic.2010.01.027","article-title":"Outer membrane proteins of Pasteurella multocida","volume":"144","author":"Hatfaludi","year":"2010","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib16","series-title":"In Pathogenesis of Bacterial Infections in Animals","article-title":"In pathogenesis of bacterial infections in animals","author":"Boyce","year":"2010"},{"key":"10.1016\/j.cimid.2022.101889_bib17","doi-asserted-by":"crossref","first-page":"961","DOI":"10.3389\/fmicb.2017.00961","article-title":"Genome-wide analyses reveal genes subject to positive selection in Pasteurella multocida","volume":"8","author":"Cao","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2020.108649","article-title":"Characterization of Pasteurella multocida isolates from rabbits in China","volume":"244","author":"Zhu","year":"2020","journal-title":"Vet. Microbiol"},{"key":"10.1016\/j.cimid.2022.101889_bib19","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3389\/fmicb.2015.00178","article-title":"A novel pro-inflammatory protein of Streptococcus suis 2 induces the Toll-like receptor 2-dependent expression of pro-inflammatory cytokines in RAW 264.7 macrophages via activation of ERK1\/2 pathway","volume":"6","author":"Zhang","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib20","doi-asserted-by":"crossref","first-page":"6614","DOI":"10.1093\/nar\/gkw569","article-title":"NCBI prokaryotic genome annotation pipeline","volume":"44","author":"Tatusova","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cimid.2022.101889_bib21","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1093\/nar\/gkm160","article-title":"RNAmmer: consistent and rapid annotation of ribosomal RNA genes","volume":"35","author":"Lagesen","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cimid.2022.101889_bib22","first-page":"1","article-title":"tRNAscan-SE: searching for tRNA genes in genomic sequences","volume":"1962","author":"Chan","year":"2009","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.cimid.2022.101889_bib23","doi-asserted-by":"crossref","first-page":"W30","DOI":"10.1093\/nar\/gkx343","article-title":"IslandViewer 4: expanded prediction of genomic islands for larger-scale datasets","volume":"45","author":"Bertelli","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cimid.2022.101889_bib24","doi-asserted-by":"crossref","first-page":"W16","DOI":"10.1093\/nar\/gkw387","article-title":"PHASTER: a better, faster version of the PHAST phage search tool","volume":"44","author":"Arndt","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cimid.2022.101889_bib25","doi-asserted-by":"crossref","first-page":"D687","DOI":"10.1093\/nar\/gky1080","article-title":"VFDB 2019: a comparative pathogenomic platform with an interactive web interface","volume":"47","author":"Liu","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cimid.2022.101889_bib26","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.vetmic.2016.10.015","article-title":"Whole-genome comparative analysis of the pathogen Piscirickettsia salmonis","volume":"196","author":"Bravo","year":"2016","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib27","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1101\/gr.2289704","article-title":"Mauve: multiple alignment of conserved genomic sequence with rearrangements","volume":"14","author":"Darling","year":"2004","journal-title":"Genome Res."},{"key":"10.1016\/j.cimid.2022.101889_bib28","doi-asserted-by":"crossref","first-page":"W78","DOI":"10.1093\/nar\/gkv487","article-title":"OrthoVenn: a web server for genome wide comparison and annotation of orthologous clusters across multiple species","volume":"43","author":"Wang","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cimid.2022.101889_bib29","doi-asserted-by":"crossref","first-page":"W52","DOI":"10.1093\/nar\/gkz333","article-title":"OrthoVenn2: a web server for whole-genome comparison and annotation of orthologous clusters across multiple species","volume":"47","author":"Xu","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cimid.2022.101889_bib30","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.gene.2018.05.084","article-title":"Pan-genomic approach shows insight of genetic divergence and pathogenic-adaptation of Pasteurella multocida","volume":"670","author":"Hurtado","year":"2018","journal-title":"Gene"},{"key":"10.1016\/j.cimid.2022.101889_bib31","article-title":"Crystallization and X-ray diffraction analysis of a novel surface-adhesin protein: protein E from Haemophilus influenzae","volume":"68","author":"Singh","year":"2012","journal-title":"Acta Crystallogr."},{"key":"10.1016\/j.cimid.2022.101889_bib32","article-title":"Function and Biogenesis of Lipopolysaccharides","volume":"8","author":"Bertani","year":"2018","journal-title":"EcoSal"},{"key":"10.1016\/j.cimid.2022.101889_bib33","doi-asserted-by":"crossref","DOI":"10.1128\/MMBR.00014-19","article-title":"Pasteurella multocida: genotypes and genomics","volume":"83","author":"Peng","year":"2019","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.cimid.2022.101889_bib34","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00681-19","article-title":"Impact of Na(+)-Translocating NADH:quinone oxidoreductase on iron uptake and nqrM expression in Vibrio cholerae","volume":"202","author":"Agarwal","year":"2020","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.cimid.2022.101889_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2019.103911","article-title":"Differences in pathogenicity and virulence-associated gene expression among Pasteurella multocida strains with high and low virulence in a lung tissue model","volume":"140","author":"Cheng","year":"2020","journal-title":"Micro Pathog."},{"key":"10.1016\/j.cimid.2022.101889_bib36","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.mib.2005.12.005","article-title":"How does Pasteurella multocida respond to the host environment?","volume":"9","author":"Boyce","year":"2006","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib37","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.vetmic.2018.04.031","article-title":"Bovine respiratory syncytial virus infection enhances Pasteurella multocida adherence on respiratory epithelial cells","volume":"220","author":"Sudaryatma","year":"2018","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179420","article-title":"Genome wide host gene expression analysis in mice experimentally infected with Pasteurella multocida","volume":"12","author":"Priya","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.cimid.2022.101889_bib39","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.3389\/fmicb.2020.01972","article-title":"Pasteurella multocida Pm0442 affects Virulence gene expression and targets TLR2 to induce inflammatory responses","volume":"11","author":"He","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib40","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0165-2427(98)00183-4","article-title":"Role of Pasteurella multocida porin on cytokine expression and release by murine splenocytes","volume":"66","author":"Iovane","year":"1999","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.cimid.2022.101889_bib41","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1128\/iai.59.4.1470-1475.1991","article-title":"Antibodies to outer membrane proteins but not to lipopolysaccharide inhibit pulmonary proliferation of Pasteurella multocida in mice","volume":"59","author":"Lu","year":"1991","journal-title":"Infect. Immun."},{"key":"10.1016\/j.cimid.2022.101889_bib42","first-page":"91","article-title":"ICEPmu1, an integrative conjugative element (ICE) of Pasteurella multocida: structure and transfer","author":"Brenner","year":"2012","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.cimid.2022.101889_bib43","doi-asserted-by":"crossref","first-page":"27646","DOI":"10.1074\/jbc.270.46.27646","article-title":"Inhibition of lipopolysaccharide biosynthesis and cell growth following inactivation of the kdtA gene in Escherichia coli","volume":"270","author":"Belunis","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cimid.2022.101889_bib44","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.tim.2010.03.006","article-title":"Cytochrome c biogenesis: the Ccm system","volume":"18","author":"Sanders","year":"2010","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.cimid.2022.101889_bib45","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0167-4838(00)00111-4","article-title":"Characterization of a heme c nitrite reductase from a non-ammonifying microorganism, Desulfovibrio vulgaris Hildenborough","volume":"1481","author":"Pereira","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cimid.2022.101889_bib46","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/978-3-030-18768-2_6","article-title":"The Periplasmic Chaperones Skp and SurA","volume":"92","author":"Mas","year":"2019","journal-title":"Subcell. Biochem"},{"key":"10.1016\/j.cimid.2022.101889_bib47","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1107\/S1744309111055503","article-title":"Crystallization and X-ray diffraction analysis of a novel surface-adhesin protein: protein E from Haemophilus influenzae","volume":"68","author":"Singh","year":"2012","journal-title":"Acta Crystallogr Sect. F. Struct. Biol. Cryst. Commun."},{"key":"10.1016\/j.cimid.2022.101889_bib48","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.vetmic.2017.11.023","article-title":"Characterization of Pasteurella multocida involved in rabbit infections","volume":"213","author":"Massacci","year":"2018","journal-title":"Vet. Microbiol"},{"key":"10.1016\/j.cimid.2022.101889_bib49","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1136\/vr.d4869","article-title":"Associations between biovar and virulence factor genes in Pasteurella multocida isolates from pigs in Spain","volume":"169","author":"Garc\u00eda","year":"2011","journal-title":"Vet. Rec."}],"container-title":["Comparative Immunology, Microbiology and Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957122001461?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147957122001461?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T06:48:25Z","timestamp":1758955705000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147957122001461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":49,"alternative-id":["S0147957122001461"],"URL":"https:\/\/doi.org\/10.1016\/j.cimid.2022.101889","relation":{},"ISSN":["0147-9571"],"issn-type":[{"value":"0147-9571","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Experimental pathogenicity and comparative genome analysis of high- and low-virulence strains of rabbit-origin Pasteurella multocida","name":"articletitle","label":"Article Title"},{"value":"Comparative Immunology, Microbiology and Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cimid.2022.101889","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101889"}}