{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:34:28Z","timestamp":1771335268665,"version":"3.50.1"},"reference-count":110,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cirug\u00eda Espa\u00f1ola (English Edition)"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.cireng.2025.800254","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T22:06:34Z","timestamp":1763762794000},"page":"800254","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Surgical management of stage IV gastric adenocarcinoma: A systematic review and expert recommendations from the Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) and the Spanish Association of Surgeons (AEC)"],"prefix":"10.1016","volume":"104","author":[{"given":"Paula","family":"Jimenez-Fonseca","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos","family":"Bruna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Gallego","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f3nica","family":"Mir\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mireia","family":"Gil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gema","family":"Mar\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delia","family":"Cort\u00e9s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Pazo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariagiulia","family":"Dal Cero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cireng.2025.800254_bib0005","first-page":"209","article-title":"Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.cireng.2025.800254_bib0010","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/bjs5.103","article-title":"International comparison of treatment strategy and survival in metastatic gastric cancer","volume":"3","author":"Claassen","year":"2019","journal-title":"BJS Open"},{"key":"10.1016\/j.cireng.2025.800254_bib0015","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1200\/JCO.2014.60.1799","article-title":"Update on metastatic gastric and esophageal cancers","volume":"33","author":"Shah","year":"2015","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0020","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/s41586-021-04161-3","article-title":"The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer","volume":"600","author":"Janjigian","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.cireng.2025.800254_bib0025","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/S0140-6736(23)00620-7","article-title":"Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 trial","volume":"401","author":"Shitara","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.cireng.2025.800254_bib0030","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0140-6736(21)00797-2","article-title":"First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial","volume":"398","author":"Janjigian","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.cireng.2025.800254_bib0035","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s11864-020-00774-4","article-title":"Targeted therapies in advanced gastric cancer","volume":"21","author":"Patel","year":"2020","journal-title":"Curr Treat Options Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2023.102226","article-title":"Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with gastric cancer","volume":"9","author":"Shitara","year":"2024","journal-title":"ESMO Open"},{"key":"10.1016\/j.cireng.2025.800254_bib0045","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.annonc.2022.07.004","article-title":"Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","volume":"33","author":"Lordick","year":"2022","journal-title":"Ann Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0050","doi-asserted-by":"crossref","first-page":"673","DOI":"10.3390\/cancers16030673","article-title":"Oligometastasis of gastric cancer: a review","volume":"16","author":"Yasufuku","year":"2024","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.cireng.2025.800254_bib0055","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.3390\/curroncol31030109","article-title":"Peritoneal metastatic gastric cancer: local treatment options and recommendations","volume":"31","author":"Acs","year":"2024","journal-title":"Curr Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0060","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.clinre.2020.02.003","article-title":"Surgical management of oligometastatic disease in gastric cancer","volume":"44","author":"Jin","year":"2020","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"10.1016\/j.cireng.2025.800254_bib0065","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1055\/a-1018-2516","article-title":"S3-Leitlinie Magenkarzinom \u2013 Diagnostik und Therapie der Adenokarzinome des Magens und des \u00f6sophagogastralen \u00dcbergangs \u2013 Langversion 2.0 \u2013 August 2019. AWMF-Registernummer: 032\/009OL","volume":"57","author":"Moehler","year":"2019","journal-title":"Z Gastroenterol"},{"key":"10.1016\/j.cireng.2025.800254_bib0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejca.2024.114062","article-title":"European clinical practice guidelines for the definition, diagnosis, and treatment of oligometastatic esophagogastric cancer (OMEC-4)","volume":"204","author":"Kroese","year":"2024","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0075","first-page":"1","article-title":"Japanese gastric cancer treatment guidelines 2021 (6th edition)","volume":"26","year":"2023","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0080","doi-asserted-by":"crossref","first-page":"3","DOI":"10.5230\/jgc.2023.23.e11","article-title":"Korean practice guidelines for gastric cancer 2022: an evidence-based, multidisciplinary approach","volume":"23","author":"Kim","year":"2023","journal-title":"J Gastric Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0085","unstructured":"NCCN Clinical Practice guidelines in oncology gastric cancer. Version 1.2024."},{"key":"10.1016\/j.cireng.2025.800254_bib0090","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/cac2.12516","article-title":"The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer, 2023","volume":"44","author":"Wang","year":"2024","journal-title":"Cancer Commun"},{"key":"10.1016\/j.cireng.2025.800254_bib0095","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1245\/s10434-023-14415-1","article-title":"Gastrectomy + Cytoreductive surgery + HIPEC for gastric cancer with Peritoneal Dissemination (PERISCOPE II)","volume":"31","author":"Sarvestani","year":"2024","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0100","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1186\/s12885-019-5640-2","article-title":"Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy versus palliative systemic chemotherapy in stomach cancer patients with peritoneal dissemination, the study protocol of a multicentre randomised controlled trial (PERISCOPE II)","volume":"19","author":"Koemans","year":"2019","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0105","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1186\/1471-2407-14-183","article-title":"GASTRICHIP: D2 resection and hyperthermic intraperitoneal chemotherapy in locally advanced gastric carcinoma: a randomized and multicenter phase III study","volume":"14","author":"Glehen","year":"2014","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0110","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.3390\/cancers15061777","article-title":"Gastric cancer with peritoneal metastases: current status and prospects for treatment","volume":"15","author":"Manzanedo","year":"2023","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.cireng.2025.800254_bib0115","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.3390\/cancers15123113","article-title":"Novel multi-modal therapies and their prognostic potential in gastric cancer","volume":"15","author":"Chidambaram","year":"2023","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.cireng.2025.800254_bib0120","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1245\/s10434-010-1039-7","article-title":"Peritoneal carcinomatosis from gastric cancer: a multi-institutional study of 159 patients treated by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy","volume":"17","author":"Glehen","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0125","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1245\/s10434-019-07450-4","article-title":"Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Gastric Cancer with Peritoneal Carcinomatosis: multicenter study of Spanish Group of Peritoneal Oncologic Surgery (GECOP)","volume":"26","author":"Manzanedo","year":"2019","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0130","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s10120-019-00978-0","article-title":"Peritoneal metastasis in gastric cancer: results from the German database","volume":"23","author":"Rau","year":"2020","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0135","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1245\/s10434-015-5081-3","article-title":"Patients with peritoneal carcinomatosis from gastric cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: is cure a possibility?","volume":"23","author":"Chia","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0140","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1001\/jamaoncol.2017.0515","article-title":"Effect of\u2009neoadjuvant chemotherapy followed by surgical resection on survival in patients with limited metastatic gastric or gastroesophageal junction cancer","volume":"3","author":"Al-Batran","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0145","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/ags3.12515","article-title":"International\u2009Retrospective Cohort Study of Conversion Therapy for Stage IV Gastric Cancer 1 (CONVO\u2010GC\u20101)","volume":"6","author":"Yoshida","year":"2022","journal-title":"Ann Gastroenterol Surg"},{"key":"10.1016\/j.cireng.2025.800254_bib0150","doi-asserted-by":"crossref","first-page":"5200","DOI":"10.3390\/cancers14215200","article-title":"Perspectives on the management of oligometastatic disease in esophago-gastric cancer","volume":"14","author":"Goetze","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.cireng.2025.800254_bib0155","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ciresp.2016.10.013","article-title":"Rehabilitaci\u00f3n multimodal en la cirug\u00eda de resecci\u00f3n g\u00e1strica","volume":"95","author":"Bruna Esteban","year":"2017","journal-title":"Cir Esp"},{"key":"10.1016\/j.cireng.2025.800254_bib0160","doi-asserted-by":"crossref","first-page":"11","DOI":"10.21037\/tgh.2019.10.04","article-title":"Enhanced recovery after surgery for gastric cancer (ERAS-GC): optimizing patient outcome","volume":"5","author":"Desiderio","year":"2020","journal-title":"Transl Gastroenterol Hepatol"},{"key":"10.1016\/j.cireng.2025.800254_bib0165","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.ejso.2018.03.019","article-title":"Surgery for metastases for esophageal-gastric cancer in the real world: data from the AGAMENON national registry","volume":"44","author":"Carmona-Bayonas","year":"2018","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0170","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1080\/07357907.2018.1551898","article-title":"Conversion surgery for unresectable advanced gastric cancer: a systematic review and meta-analysis","volume":"37","author":"Du","year":"2019","journal-title":"Cancer Invest"},{"key":"10.1016\/j.cireng.2025.800254_bib0175","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ejca.2023.02.015","article-title":"Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: a Delphi consensus study in Europe","volume":"185","author":"Kroese","year":"2023","journal-title":"Eur J Cancer"},{"issue":"2","key":"10.1016\/j.cireng.2025.800254_bib0180","doi-asserted-by":"crossref","first-page":"704","DOI":"10.3390\/jcm12020704","article-title":"Survival Outcomes of Hepatectomy in Gastric Cancer Liver Metastasis: A Systematic Review and Meta-Analysis","volume":"12","author":"Conde Monroy","year":"2023","journal-title":"J Clin Med"},{"key":"10.1016\/j.cireng.2025.800254_bib0185","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.annonc.2022.05.520","article-title":"ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group","volume":"33","author":"Pascual","year":"2022","journal-title":"Ann Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0190","doi-asserted-by":"crossref","first-page":"2830","DOI":"10.1200\/JCO.21.02745","article-title":"Integration of genomic biology into therapeutic strategies of gastric cancer peritoneal metastasis","volume":"40","author":"Gwee","year":"2022","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0195","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/s41571-022-00675-5","article-title":"Advances in the management of peritoneal malignancies","volume":"19","author":"Kepenekian","year":"2022","journal-title":"Nat Rev Clin Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0200","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1007\/s12029-023-00994-5","article-title":"Regional therapy approaches for gastric cancer with limited peritoneal disease","volume":"55","author":"Li","year":"2024","journal-title":"J Gastrointest Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0205","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s00268-009-0355-1","article-title":"Significance of lavage cytology in advanced gastric cancer patients","volume":"34","author":"Fukagawa","year":"2010","journal-title":"World J Surg"},{"key":"10.1016\/j.cireng.2025.800254_bib0210","doi-asserted-by":"crossref","first-page":"405","DOI":"10.6004\/jnccn.2024.7013","article-title":"Systemic treatment strategies and outcomes of patients with synchronous peritoneal metastases of gastric origin: a nationwide population-based study","volume":"22","author":"Guchelaar","year":"2024","journal-title":"J Natl Comprehens Cancer Netw"},{"key":"10.1016\/j.cireng.2025.800254_bib0215","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1200\/JCO.2018.77.8613","article-title":"Phase III trial comparing intraperitoneal and intravenous paclitaxel Plus S-1 versus cisplatin Plus S-1 in patients with gastric cancer with peritoneal metastasis: PHOENIX-GC trial","volume":"36","author":"Ishigami","year":"2018","journal-title":"J Clin Oncol"},{"issue":"suppl 4","key":"10.1016\/j.cireng.2025.800254_bib0220","article-title":"Intraperitoneal and intravenous paclitaxel plus S-1 versus intravenous paclitaxel plus S-1 in gastric cancer patients with peritoneal metastasis: results from the multicenter, randomized, phase 3 DRAGON-01 trial","volume":"43","author":"Yan","year":"2025","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0225","doi-asserted-by":"crossref","first-page":"9060","DOI":"10.1245\/s10434-021-10157-0","article-title":"Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for gastric cancer with synchronous peritoneal metastases: multicenter study of \u2018Italian Peritoneal Surface Malignancies Oncoteam\u2014S.I.C.O\u2019","volume":"28","author":"Marano","year":"2021","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0230","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1186\/s12885-017-3730-6","article-title":"Cytoreductive surgery and hyperthermic intra-operative peritoneal chemotherapy with cisplatin for gastric peritoneal carcinomatosis monocentric phase-2 nonrandomized prospective clinical trial","volume":"17","author":"Topal","year":"2017","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0235","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1245\/s10434-022-12761-0","article-title":"Cytoreduction and HIPEC for gastric carcinomatosis: multi-institutional analysis of two phase II clinical trials","volume":"30","author":"Green","year":"2023","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0240","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/jso.23633","article-title":"Impact of maximal cytoreductive surgery plus regional heated intraperitoneal chemotherapy (HIPEC) on outcome of patients with peritoneal carcinomatosis of gastric origin: results of the GYMSSA trial","volume":"110","author":"Rudloff","year":"2014","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0245","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1245\/s10434-011-1631-5","article-title":"Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from gastric cancer: final results of a phase III randomized clinical trial","volume":"18","author":"Yang","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0250","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1200\/JCO.22.02867","article-title":"Effect of hyperthermic intraperitoneal chemotherapy on cytoreductive surgery in gastric cancer with synchronous peritoneal metastases: the phase III GASTRIPEC-I trial","volume":"42","author":"Rau","year":"2024","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0255","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1200\/JCO.18.01688","article-title":"Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for gastric cancer with peritoneal metastases (CYTO-CHIP study): a propensity score analysis","volume":"37","author":"Bonnot","year":"2019","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0260","doi-asserted-by":"crossref","first-page":"7528","DOI":"10.1245\/s10434-022-12312-7","article-title":"Impact of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in the treatment of gastric cancer with peritoneal carcinomatosis: a systematic review and meta-analysis","volume":"29","author":"Martins","year":"2022","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0265","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1245\/s10434-018-07140-7","article-title":"Laparoscopic hyperthermic intraperitoneal chemotherapy is safe for patients with peritoneal metastases from gastric cancer and may lead to gastrectomy","volume":"26","author":"Newhook","year":"2019","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0270","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ejso.2020.05.021","article-title":"Pressurized intraperitoneal aerosol chemotherapy (PIPAC) for unresectable peritoneal metastasis from gastric cancer","volume":"47","author":"Alyami","year":"2021","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0275","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1007\/s10120-016-0684-3","article-title":"Surgery after intraperitoneal and systemic chemotherapy for gastric cancer with peritoneal metastasis or positive peritoneal cytology findings","volume":"20","author":"Ishigami","year":"2017","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0280","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1245\/s10434-008-0055-3","article-title":"Does neoadjuvant treatment for gastric cancer patients with positive peritoneal cytology at staging laparoscopy improve survival?","volume":"15","author":"Badgwell","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0285","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s00595-014-0979-0","article-title":"The clinical significance of potentially curative resection for gastric cancer following the clearance of free cancer cells in the peritoneal cavity by induction chemotherapy","volume":"45","author":"Aizawa","year":"2015","journal-title":"Surg Today"},{"key":"10.1016\/j.cireng.2025.800254_bib0290","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s13193-011-0074-6","article-title":"Positive peritoneal cytology in patients with gastric cancer: natural history and outcome of 291 patients","volume":"2","author":"Mezhir","year":"2011","journal-title":"Indian J Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0295","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/ags3.12060","article-title":"Treatment of patients with peritoneal metastases from gastric cancer","volume":"2","author":"Kitayama","year":"2018","journal-title":"Ann Gastroenterol Surg"},{"key":"10.1016\/j.cireng.2025.800254_bib0300","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1016\/j.ejso.2018.06.036","article-title":"Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with gastric cancer and peritoneal carcinomatosis","volume":"44","author":"Rihuete Caro","year":"2018","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0305","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.21037\/jgo-20-232","article-title":"Review of management and treatment of peritoneal metastases from gastric cancer origin","volume":"12","author":"Manzanedo","year":"2021","journal-title":"J Gastrointest Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0310","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s12885-015-1081-8","article-title":"Incidence, time course and independent risk factors for metachronous peritoneal carcinomatosis of gastric origin \u2013 a longitudinal experience from a prospectively collected database of 1108 patients","volume":"15","author":"Seyfried","year":"2015","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0315","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/s41572-021-00326-6","article-title":"Primary and metastatic peritoneal surface malignancies","volume":"7","author":"Cort\u00e9s-Guiral","year":"2021","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.cireng.2025.800254_bib0320","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/1097-0142(19880115)61:2<232::AID-CNCR2820610205>3.0.CO;2-U","article-title":"Prophylactic therapy for peritoneal recurrence of gastric cancer by continuous hyperthermic peritoneal perfusion with mitomycin C","volume":"61","author":"Koga","year":"1988","journal-title":"Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0325","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/BF00348209","article-title":"Continuous hyperthermic peritoneal perfusion for the prevention of peritoneal recurrence of gastric cancer: randomized controlled study","volume":"18","author":"Fujimura","year":"1994","journal-title":"World J Surg"},{"key":"10.1016\/j.cireng.2025.800254_bib0330","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1002\/1097-0142(19940415)73:8<2048::AID-CNCR2820730806>3.0.CO;2-Q","article-title":"Intraperitoneal thermochemotherapy for prevention of peritoneal recurrence of gastric cancer. Final results of a randomized controlled study","volume":"73","author":"Hamazoe","year":"1994","journal-title":"Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0335","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1186\/s12885-019-6125-z","article-title":"Prophylactic HIPEC with radical D2 gastrectomy improves survival and peritoneal recurrence rates for locally advanced gastric cancer: personal experience from a randomized case control study","volume":"19","author":"Beeharry","year":"2019","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0340","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1016\/j.ejso.2019.07.030","article-title":"Hyperthermic intraperitoneal chemotherapy in serosa-invasive gastric cancer patients","volume":"45","author":"Reutovich","year":"2019","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0345","doi-asserted-by":"crossref","first-page":"782","DOI":"10.4251\/wjgo.v12.i7.782","article-title":"Role of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer","volume":"12","author":"Xie","year":"2020","journal-title":"World J Gastrointest Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0350","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/s12885-021-07925-2","article-title":"Phase II trial of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer after curative surgery","volume":"21","author":"Fan","year":"2021","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0355","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1080\/02656736.2022.2028018","article-title":"A novel method of bedside hyperthermic intraperitoneal chemotherapy as adjuvant therapy for stage-III gastric cancer","volume":"39","author":"Liu","year":"2022","journal-title":"Int J Hypertherm"},{"key":"10.1016\/j.cireng.2025.800254_bib0360","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.gassur.2024.04.007","article-title":"Prophylaxis and treatment of peritoneal carcinomatosis of gastric origin using hyperthermic intraperitoneal chemotherapy: a systematic review and meta-analysis of randomized trials","volume":"28","author":"Stefano","year":"2024","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.cireng.2025.800254_bib0365","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1200\/JCO.1994.12.5.970","article-title":"Adjuvant intraperitoneal cisplatin chemotherapy does not improve long-term survival after surgery for advanced gastric cancer","volume":"12","author":"Sautner","year":"1994","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0370","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1002\/(SICI)1097-0142(19990201)85:3<529::AID-CNCR3>3.0.CO;2-9","article-title":"Successful intraperitoneal hyperthermic chemoperfusion for the prevention of postoperative peritoneal recurrence in patients with advanced gastric carcinoma","volume":"85","author":"Fujimoto","year":"1999","journal-title":"Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0375","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s00268-001-0067-7","article-title":"Indications for early postoperative intraperitoneal chemotherapy of advanced gastric\u2009cancer: results of a prospective randomized trial","volume":"25","author":"Yu","year":"2001","journal-title":"World J Surg"},{"key":"10.1016\/j.cireng.2025.800254_bib0380","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/SLA.0b013e3181b0c80e","article-title":"Extensive intraoperative peritoneal lavage as a standard prophylactic strategy for peritoneal recurrence in patients with gastric carcinoma","volume":"250","author":"Kuramoto","year":"2009","journal-title":"Ann Surg"},{"key":"10.1016\/j.cireng.2025.800254_bib0385","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.3892\/etm.2014.1599","article-title":"Effect of neoadjuvant chemotherapy combined with hyperthermic intraperitoneal perfusion chemotherapy on advanced gastric cancer","volume":"7","author":"Cui","year":"2014","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.cireng.2025.800254_bib0390","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1002\/jso.26894","article-title":"Current role for cytoreduction and HIPEC for gastric cancer with peritoneal disease","volume":"125","author":"Khan","year":"2022","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0395","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1245\/s10434-023-13278-w","article-title":"Feasibility and safety of laparoscopic D2 gastrectomy in combination with pressurized intraperitoneal aerosol chemotherapy (PIPAC) in patients with gastric cancer at high risk of recurrence\u2014the PIPAC-OPC4 study","volume":"30","author":"Graversen","year":"2023","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0400","doi-asserted-by":"crossref","first-page":"5666","DOI":"10.3390\/jcm10235666","article-title":"Intraperitoneal chemotherapy as adjuvant or perioperative chemotherapy for patients with type 4 scirrhous gastric cancer: PHOENIX-GC2 trial","volume":"10","author":"Ishigami","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.cireng.2025.800254_bib0405","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00280-013-2332-5","article-title":"Enhanced efficacy of postoperative adjuvant chemotherapy in advanced gastric cancer: results from a phase 3 randomized trial (AMC0101)","volume":"73","author":"Kang","year":"2014","journal-title":"Cancer Chemother Pharmacol"},{"issue":"1","key":"10.1016\/j.cireng.2025.800254_bib0410","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s12029-025-01325-6","article-title":"Oligometastatic Gastric Cancer: Novel Considerations for Personalized Approach","volume":"56","author":"Kyrochristou","year":"2025","journal-title":"J Gastrointest Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0415","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s10120-024-01479-5","article-title":"International consensus on the management of metastatic gastric cancer: step by step in the foggy landscape","volume":"27","author":"Morgagni","year":"2024","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0420","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1245\/s10434-017-5857-8","article-title":"Incidence and prognostic value of metastases to \u201cposterior\u201d and para-aortic lymph nodes in resectable gastric cancer","volume":"24","author":"Marrelli","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0425","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1007\/s10120-019-00981-5","article-title":"An integrated analysis of two phase II trials (JCOG0001 and JCOG0405) of preoperative chemotherapy followed by D3 gastrectomy for gastric cancer with extensive lymph node metastasis","volume":"22","author":"Katayama","year":"2019","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0430","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1186\/s12957-015-0627-1","article-title":"Gastrectomy in comprehensive treatment of advanced gastric cancer with synchronous liver metastasis: a prospectively comparative study","volume":"13","author":"Li","year":"2015","journal-title":"World J Surg Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0435","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.3390\/jcm10051141","article-title":"Efficacy of surgery for the treatment of gastric cancer liver metastases: a systematic review of the literature and meta-analysis of prognostic factors","volume":"10","author":"Marte","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.cireng.2025.800254_bib0440","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ctrv.2018.05.010","article-title":"Long-term survival after liver metastasectomy in gastric cancer: systematic review and meta-analysis of prognostic factors","volume":"69","author":"Montagnani","year":"2018","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.cireng.2025.800254_bib0445","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2021.103313","article-title":"Surgical treatment of gastric cancer liver metastases: systematic review and meta-analysis of long-term outcomes and prognostic factors","volume":"163","author":"Granieri","year":"2021","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.cireng.2025.800254_bib0450","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3389\/fonc.2019.00671","article-title":"Frequency and prognosis of pulmonary metastases in newly diagnosed gastric cancer","volume":"9","author":"Sun","year":"2019","journal-title":"Front Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0455","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s12032-015-0718-4","article-title":"Pulmonary metastases from gastric cancer: is there any indication for lung metastasectomy? A systematic review","volume":"33","author":"Aurello","year":"2016","journal-title":"Med Oncol"},{"issue":"2","key":"10.1016\/j.cireng.2025.800254_bib0460","doi-asserted-by":"crossref","first-page":"135","DOI":"10.2217\/fon-2021-1315","article-title":"The concept of oligometastatic disease in gastric cancer: reality or fiction?","volume":"18","author":"Kassar","year":"2022","journal-title":"Future Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0465","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.2024.42.3_suppl.247","volume":"42","author":"Al-Batran","year":"2024","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0470","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.3390\/cancers12092598","article-title":"Multimodality treatment in metastatic gastric cancer: from past to next future","volume":"12","author":"Parisi","year":"2020","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.cireng.2025.800254_bib0475","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000013525","article-title":"Influence of thermal ablation of hepatic metastases from gastric adenocarcinoma on long-term survival","volume":"97","author":"Tang","year":"2018","journal-title":"Medicine"},{"key":"10.1016\/j.cireng.2025.800254_bib0480","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ijsu.2017.08.578","article-title":"Adjuvant hepatic artery infusion chemotherapy after hemihepatectomy for gastric cancer liver metastases","volume":"46","author":"Fukami","year":"2017","journal-title":"Int J Surg"},{"key":"10.1016\/j.cireng.2025.800254_bib0485","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.4103\/0366-6999.162497","article-title":"Comparison of therapeutic efficacy between gastrectomy with transarterial chemoembolization plus systemic chemotherapy and systemic chemotherapy alone in gastric cancer with synchronous liver metastasis","volume":"128","author":"Liu","year":"2015","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.cireng.2025.800254_bib0490","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.lungcan.2016.04.012","article-title":"Stereotactic body radiotherapy (SBRT) for medically inoperable lung metastases\u2014a pooled analysis of the German working group \u201cstereotactic radiotherapy\u201d","volume":"97","author":"Rieber","year":"2016","journal-title":"Lung Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0495","doi-asserted-by":"crossref","DOI":"10.2174\/0115734056246452231011042418","article-title":"Radiomics in the diagnosis of gastric cancer: current status and future perspectives","volume":"20","author":"Wang","year":"2023","journal-title":"Curr Med Imaging Rev"},{"key":"10.1016\/j.cireng.2025.800254_bib0500","doi-asserted-by":"crossref","first-page":"375","DOI":"10.5230\/jgc.2023.23.e31","article-title":"The role of artificial intelligence in gastric cancer: surgical and therapeutic perspectives: a comprehensive review","volume":"23","author":"Lee","year":"2023","journal-title":"J Gastric Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0505","doi-asserted-by":"crossref","first-page":"5408","DOI":"10.3748\/wjg.v26.i36.5408","article-title":"Artificial intelligence in gastric cancer: application and future perspectives","volume":"26","author":"Niu","year":"2020","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cireng.2025.800254_bib0510","first-page":"130","article-title":"PET\/CT FAPI: procedure and evidence review in oncology","volume":"43","author":"Caresia","year":"2024","journal-title":"Rev Esp Med Nucl Imagen Mol (Engl Ed)"},{"key":"10.1016\/j.cireng.2025.800254_bib0515","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s13045-023-01451-3","article-title":"Gastric cancer treatment: recent progress and future perspectives","volume":"16","author":"Guan","year":"2023","journal-title":"J Hematol Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0520","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2022.100563","article-title":"Margetuximab with retifanlimab as first-line therapy in HER2+\/PD-L1+ unresectable or metastatic gastroesophageal adenocarcinoma: MAHOGANY cohort A","volume":"7","author":"Catenacci","year":"2022","journal-title":"ESMO Open"},{"key":"10.1016\/j.cireng.2025.800254_bib0525","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1002\/cac2.12214","article-title":"Efficacy and safety of a novel anti\u2010HER2 therapeutic antibody RC48 in patients with HER2\u2010overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer: a single\u2010arm phase II study","volume":"41","author":"Peng","year":"2021","journal-title":"Cancer Commun"},{"key":"10.1016\/j.cireng.2025.800254_bib0530","article-title":"Phase 1 multicenter, dose-expansion study of ARX788 as monotherapy in HER2-positive advanced gastric and gastroesophageal junction adenocarcinoma","volume":"3","author":"Zhang","year":"2022","journal-title":"Cell Rep Med"},{"key":"10.1016\/j.cireng.2025.800254_bib0535","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1016\/j.bulcan.2019.03.012","article-title":"HER2-specific chimeric antigen receptor-engineered natural killer cells combined with apatinib for the treatment of gastric cancer","volume":"106","author":"Wu","year":"2019","journal-title":"Bull Cancer"},{"key":"10.1016\/j.cireng.2025.800254_bib0540","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s13045-022-01325-0","article-title":"Immune checkpoint modulators in cancer immunotherapy: recent advances and emerging concepts","volume":"15","author":"Wang","year":"2022","journal-title":"J Hematol Oncol"},{"key":"10.1016\/j.cireng.2025.800254_bib0545","doi-asserted-by":"crossref","first-page":"543","DOI":"10.3390\/biomedicines10030543","article-title":"Gastric cancer: mechanisms, biomarkers, and therapeutic approaches","volume":"10","author":"Choi","year":"2022","journal-title":"Biomedicines"},{"key":"10.1016\/j.cireng.2025.800254_bib0550","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12935-024-03209-4","article-title":"Clinical applications and perspectives of circulating tumor DNA in gastric cancer","volume":"24","author":"Li","year":"2024","journal-title":"Cancer Cell Int"}],"container-title":["Cirug\u00eda Espa\u00f1ola (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2173507725002467?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2173507725002467?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:52:01Z","timestamp":1771332721000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2173507725002467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":110,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S2173507725002467"],"URL":"https:\/\/doi.org\/10.1016\/j.cireng.2025.800254","relation":{},"ISSN":["2173-5077"],"issn-type":[{"value":"2173-5077","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Surgical management of stage IV gastric adenocarcinoma: A systematic review and expert recommendations from the Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) and the Spanish Association of Surgeons (AEC)","name":"articletitle","label":"Article Title"},{"value":"Cirug\u00eda Espa\u00f1ola (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cireng.2025.800254","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.ciresp.2025.800254","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 AEC. Published by Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"800254"}}