{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:23:18Z","timestamp":1791919398633,"version":"4.3.4"},"reference-count":79,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["onlinecjc.ca","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Cardiology"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.cjca.2014.03.013","type":"journal-article","created":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T13:35:18Z","timestamp":1395236118000},"page":"1012-1026","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Exercise Testing and Stress Imaging in Valvular Heart Disease"],"prefix":"10.1016","volume":"30","author":[{"given":"Christine","family":"Henri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc A.","family":"Pi\u00e9rard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizio","family":"Lancellotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois-Pierre","family":"Mongeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Pibarot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ars\u00e8ne J.","family":"Basmadjian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cjca.2014.03.013_bib1","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1161\/CIR.0000000000000029","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"129","author":"Nishimura","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib2","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1093\/eurheartj\/ehs109","article-title":"Guidelines on the management of valvular heart disease (version 2012): Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology, European Association for Cardio-Thoracic Surgery","volume":"33","author":"Vahanian","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib3","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1016\/j.jacc.2009.07.046","article-title":"The emerging role of exercise testing and stress echocardiography in valvular heart disease","volume":"54","author":"Picano","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib4","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1093\/eurheartj\/ehn492","article-title":"Stress echocardiography expert consensus statement\u2013executive summary: European Association of Echocardiography (EAE) (a registered branch of the ESC)","volume":"30","author":"Sicari","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib5","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.echo.2007.07.003","article-title":"American Society of Echocardiography recommendations for performance, interpretation, and application of stress echocardiography","volume":"20","author":"Pellikka","year":"2007","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib6","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/HCO.0b013e3283632b41","article-title":"The role of stress testing in evaluation of asymptomatic patients with aortic stenosis","volume":"28","author":"Lancellotti","year":"2013","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib7","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1161\/01.CIR.0000034670.06526.15","article-title":"ACC\/AHA 2002 guideline update for exercise testing: summary article: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines)","volume":"106","author":"Gibbons","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib8","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0195-668X(03)00201-X","article-title":"A\u00a0prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease","volume":"24","author":"Iung","year":"2003","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib9","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1161\/CIRCULATIONAHA.108.808857","article-title":"Risk score for predicting outcome in patients with asymptomatic aortic stenosis","volume":"120","author":"Monin","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib10","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1136\/heart.86.4.381","article-title":"Treatment decision in asymptomatic aortic valve stenosis: role of exercise testing","volume":"86","author":"Amato","year":"2001","journal-title":"Heart"},{"key":"10.1016\/j.cjca.2014.03.013_bib11","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1093\/eurheartj\/ehi250","article-title":"Exercise testing to stratify risk in aortic stenosis","volume":"26","author":"Das","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib12","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.amjcard.2009.05.044","article-title":"Meta-analysis of prognostic value of stress testing in patients with asymptomatic severe aortic stenosis","volume":"104","author":"Rafique","year":"2009","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib13","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jtcvs.2007.08.058","article-title":"The benefits of early valve replacement in asymptomatic patients with severe aortic stenosis","volume":"135","author":"Brown","year":"2008","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.cjca.2014.03.013_bib14","doi-asserted-by":"crossref","first-page":"I377","DOI":"10.1161\/CIRCULATIONAHA.104.523274","article-title":"Prognostic importance of quantitative exercise Doppler echocardiography in asymptomatic valvular aortic stenosis","volume":"112","author":"Lancellotti","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib15","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1093\/eurheartj\/ehq076","article-title":"Usefulness of exercise-stress echocardiography for risk stratification of true asymptomatic patients with aortic valve stenosis","volume":"31","author":"Marechaux","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/ejechocard\/jen163","article-title":"Argument for a Doppler echocardiography during exercise in assessing asymptomatic patients with severe aortic stenosis","volume":"10","author":"Leurent","year":"2009","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib17","first-page":"338","article-title":"Determinants of an abnormal response to exercise in patients with asymptomatic valvular aortic stenosis","volume":"9","author":"Lancellotti","year":"2008","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib18","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1111\/j.1540-8175.2007.00501.x","article-title":"Left ventricular response to exercise in aortic stenosis: an exercise echocardiographic study","volume":"24","author":"Marechaux","year":"2007","journal-title":"Echocardiography"},{"key":"10.1016\/j.cjca.2014.03.013_bib19","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/ejechocard\/jeq187","article-title":"Impact of aortic stenosis on longitudinal myocardial deformation during exercise","volume":"12","author":"Donal","year":"2011","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib20","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1161\/CIRCULATIONAHA.111.088427","article-title":"Determinants and prognostic significance of exercise pulmonary hypertension in asymptomatic severe aortic stenosis","volume":"126","author":"Lancellotti","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib21","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jacc.2009.12.073","article-title":"Exercise-induced changes in degenerative mitral regurgitation","volume":"56","author":"Magne","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib22","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1161\/CIRCULATIONAHA.110.938241","article-title":"Exercise pulmonary hypertension in asymptomatic degenerative mitral regurgitation","volume":"122","author":"Magne","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib23","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1161\/CIRCIMAGING.112.000162","article-title":"Prognostic significance of exercise-induced right ventricular dysfunction in asymptomatic degenerative mitral regurgitation","volume":"6","author":"Kusunose","year":"2013","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.cjca.2014.03.013_bib24","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1093\/eurheartj\/eht345","article-title":"Left ventricular contractile reserve in asymptomatic primary mitral regurgitation","volume":"35","author":"Magne","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib25","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1136\/hrt.2009.190942","article-title":"Risk stratification in asymptomatic moderate to severe aortic stenosis: the importance of the valvular, arterial and ventricular interplay","volume":"96","author":"Lancellotti","year":"2010","journal-title":"Heart"},{"key":"10.1016\/j.cjca.2014.03.013_bib26","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1093\/ejechocard\/jen299","article-title":"Impact of impaired myocardial deformations on exercise tolerance and prognosis in patients with asymptomatic aortic stenosis","volume":"10","author":"Lafitte","year":"2009","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib27","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.amjcard.2009.09.043","article-title":"Prognostic effect of long-axis left ventricular dysfunction and B-type natriuretic peptide levels in asymptomatic aortic stenosis","volume":"105","author":"Lancellotti","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib28","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.ahj.2004.03.049","article-title":"Tissue Doppler imaging in patients with moderate to severe aortic valve stenosis: clinical usefulness and diagnostic accuracy","volume":"148","author":"Bruch","year":"2004","journal-title":"Am Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib29","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/j.jacc.2012.06.051","article-title":"Low-flow, low-gradient aortic stenosis with normal and depressed left ventricular ejection fraction","volume":"60","author":"Pibarot","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib30","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0002-9149(00)80078-8","article-title":"Usefulness of dobutamine echocardiography in distinguishing severe from nonsevere valvular aortic stenosis in patients with depressed left ventricular function and low transvalvular gradients","volume":"75","author":"deFilippi","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib31","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1016\/S0735-1097(01)01339-0","article-title":"Aortic stenosis with severe left ventricular dysfunction and low transvalvular pressure gradients: risk stratification by low-dose dobutamine echocardiography","volume":"37","author":"Monin","year":"2001","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib32","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1161\/01.CIR.0000079171.43055.46","article-title":"Low-gradient aortic stenosis: operative risk stratification and predictors for long-term outcome: a multicenter study using dobutamine stress hemodynamics","volume":"108","author":"Monin","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib33","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1378\/chest.119.6.1766","article-title":"Dobutamine echocardiography in patients with aortic stenosis and left ventricular dysfunction: predicting outcome as a function of management strategy","volume":"119","author":"Schwammenthal","year":"2001","journal-title":"Chest"},{"key":"10.1016\/j.cjca.2014.03.013_bib34","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1161\/CIRCULATIONAHA.105.557678","article-title":"Projected valve area at normal flow rate improves the assessment of stenosis severity in patients with low-flow, low-gradient aortic stenosis: the multicenter TOPAS (Truly or Pseudo-Severe Aortic Stenosis) study","volume":"113","author":"Blais","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib35","doi-asserted-by":"crossref","first-page":"S234","DOI":"10.1161\/CIRCULATIONAHA.107.757427","article-title":"Predictors of outcomes in low-flow, low-gradient aortic stenosis: results of the multicenter TOPAS Study","volume":"118","author":"Clavel","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib36","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1136\/hrt.2005.074815","article-title":"Stress testing in valve disease","volume":"93","author":"Pierard","year":"2007","journal-title":"Heart"},{"key":"10.1016\/j.cjca.2014.03.013_bib37","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1093\/eurheartj\/ehs176","article-title":"Outcomes of pseudo-severe aortic stenosis under conservative treatment","volume":"33","author":"Fougeres","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib38","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1016\/j.jacc.2009.02.026","article-title":"Outcome after aortic valve replacement for low-flow\/low-gradient aortic stenosis without contractile reserve on dobutamine stress echocardiography","volume":"53","author":"Tribouilloy","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib39","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1161\/CIRCULATIONAHA.105.568824","article-title":"Influence of preoperative left ventricular contractile reserve on postoperative ejection fraction in low-gradient aortic stenosis","volume":"113","author":"Quere","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib40","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1136\/hrt.2010.198853","article-title":"Measurement of aortic valve calcification using multislice computed tomography: correlation with haemodynamic severity of aortic stenosis and clinical implication for patients with low ejection fraction","volume":"97","author":"Cueff","year":"2011","journal-title":"Heart"},{"key":"10.1016\/j.cjca.2014.03.013_bib41","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1016\/j.jacc.2013.08.1621","article-title":"The complex nature of discordant severe calcified aortic valve disease grading: new insights from combined Doppler-echocardiographic and computed tomographic study","volume":"62","author":"Clavel","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib42","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.echo.2010.02.002","article-title":"Validation of conventional and simplified methods to calculate projected valve area at normal flow rate in patients with low flow, low gradient aortic stenosis: the multicenter TOPAS (True or Pseudo Severe Aortic Stenosis) study","volume":"23","author":"Clavel","year":"2010","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib43","doi-asserted-by":"crossref","first-page":"2856","DOI":"10.1161\/CIRCULATIONAHA.106.668681","article-title":"Paradoxical low-flow, low-gradient severe aortic stenosis despite preserved ejection fraction is associated with higher afterload and reduced survival","volume":"115","author":"Hachicha","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib44","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.jacc.2011.12.054","article-title":"Outcome of patients with aortic stenosis, small valve area, and low-flow, low-gradient despite preserved left ventricular ejection fraction","volume":"60","author":"Clavel","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib45","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jcmg.2012.10.015","article-title":"Stress echocardiography to assess stenosis severity and predict outcome in patients with paradoxical low-flow, low-gradient aortic stenosis and preserved LVEF","volume":"6","author":"Clavet","year":"2013","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.cjca.2014.03.013_bib46","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1161\/CIRCULATIONAHA.111.060319","article-title":"Hemodynamics in the cardiac catheterization laboratory of the 21st century","volume":"125","author":"Nishimura","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib47","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1161\/01.CIR.99.14.1851","article-title":"Mortality and morbidity of aortic regurgitation in clinical practice. A long-term follow-up study","volume":"99","author":"Dujardin","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib48","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1136\/heart.85.1.30","article-title":"Assessment of left ventricular long axis contraction can detect early myocardial dysfunction in asymptomatic patients with severe aortic regurgitation","volume":"85","author":"Vinereanu","year":"2001","journal-title":"Heart"},{"key":"10.1016\/j.cjca.2014.03.013_bib49","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1136\/heart.84.6.606","article-title":"Exercise echocardiography predicts development of left ventricular dysfunction in medically and surgically treated patients with asymptomatic severe aortic regurgitation","volume":"84","author":"Wahi","year":"2000","journal-title":"Heart"},{"key":"10.1016\/j.cjca.2014.03.013_bib50","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jcmg.2008.09.009","article-title":"Exercise radionuclide ventriculography for predicting post-operative left ventricular function in chronic aortic regurgitation","volume":"2","author":"Tamas","year":"2009","journal-title":"JACC Cardiovascular Imaging"},{"key":"10.1016\/j.cjca.2014.03.013_bib51","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/ejechocard\/jeq030","article-title":"European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 1: aortic and pulmonary regurgitation (native valve disease)","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib52","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/S0002-9149(97)00689-9","article-title":"Comparison of exercise and dobutamine stress echocardiography in assessing mitral stenosis","volume":"80","author":"Hecker","year":"1997","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib53","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.jacc.2003.09.037","article-title":"Dobutamine stress echocardiography for noninvasive assessment and risk stratification of patients with rheumatic mitral stenosis","volume":"43","author":"Reis","year":"2004","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib54","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.echo.2011.01.006","article-title":"Early hemodynamic changes versus peak values: what is more useful to predict occurrence of dyspnea during stress echocardiography in patients with asymptomatic mitral stenosis?","volume":"24","author":"Brochet","year":"2011","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib55","doi-asserted-by":"crossref","first-page":"2378","DOI":"10.1161\/01.CIR.102.19.2378","article-title":"Impact of atrioventricular compliance on pulmonary artery pressure in mitral stenosis: an exercise echocardiographic study","volume":"102","author":"Schwammenthal","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib56","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.amjcard.2005.03.094","article-title":"Usefulness of measuring net atrioventricular compliance by Doppler echocardiography in patients with mitral stenosis","volume":"96","author":"Li","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib57","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1016\/j.jacc.2006.02.043","article-title":"Cardiopulmonary exercise testing determination of functional capacity in mitral regurgitation: physiologic and outcome implications","volume":"47","author":"Messika-Zeitoun","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"suppl B","key":"10.1016\/j.cjca.2014.03.013_bib58","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/eurheartj\/12.suppl_B.22","article-title":"Right ventricular function in severe non-ischaemic mitral insufficiency","volume":"12","author":"Borer","year":"1991","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib59","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/ejechocard\/jeq031","article-title":"European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspid regurgitation (native valve disease)","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib60","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1136\/hrt.2004.047613","article-title":"Functional and prognostic implications of left ventricular contractile reserve in patients with asymptomatic severe mitral regurgitation","volume":"91","author":"Lee","year":"2005","journal-title":"Heart"},{"key":"10.1016\/j.cjca.2014.03.013_bib61","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.echo.2008.09.023","article-title":"Importance of left ventricular longitudinal function and functional reserve in patients with degenerative mitral regurgitation: assessment by two-dimensional speckle tracking","volume":"21","author":"Lancellotti","year":"2008","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.cjca.2014.03.013_bib62","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1093\/eurjhf\/hfs114","article-title":"Prognostic importance of exercise brain natriuretic peptide in asymptomatic degenerative mitral regurgitation","volume":"14","author":"Magne","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cjca.2014.03.013_bib63","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1136\/hrt.2007.134833","article-title":"How to manage ischaemic mitral regurgitation","volume":"94","author":"Lancellotti","year":"2008","journal-title":"Heart"},{"key":"10.1016\/j.cjca.2014.03.013_bib64","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1161\/01.CIR.103.13.1759","article-title":"Ischemic mitral regurgitation: long-term outcome and prognostic implications with quantitative Doppler assessment","volume":"103","author":"Grigioni","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib65","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jacc.2004.10.030","article-title":"Contribution of ischemic mitral regurgitation to congestive heart failure after myocardial infarction","volume":"45","author":"Grigioni","year":"2005","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib66","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1056\/NEJMoa040532","article-title":"The role of ischemic mitral regurgitation in the pathogenesis of acute pulmonary edema","volume":"51","author":"Pierard","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cjca.2014.03.013_bib67","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1016\/j.jacc.2003.04.002","article-title":"Determinants of exercise-induced changes in mitral regurgitation in patients with coronary artery disease and left ventricular dysfunction","volume":"42","author":"Lancellotti","year":"2003","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib68","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1093\/eurheartj\/ehi189","article-title":"Long-term outcome of patients with heart failure and dynamic functional mitral regurgitation","volume":"26","author":"Lancellotti","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib69","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1161\/CIRCULATIONAHA.104.486720","article-title":"Ischemic mitral regurgitation on the threshold of a solution: from paradoxes to unifying concepts","volume":"112","author":"Levine","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib70","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1161\/CIRCULATIONAHA.107.742486","article-title":"Cardiovascular magnetic resonance imaging for valvular heart disease: technique and validation","volume":"119","author":"Cawley","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib71","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.jacc.2008.08.064","article-title":"Noninvasive detection of fibrosis applying contrast-enhanced cardiac magnetic resonance in different forms of left ventricular hypertrophy relation to remodeling","volume":"53","author":"Rudolph","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib72","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1161\/CIRCULATIONAHA.109.930636","article-title":"Equilibrium contrast cardiovascular magnetic resonance for the measurement of diffuse myocardial fibrosis: preliminary validation in humans","volume":"122","author":"Flett","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib73","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1056\/NEJM200011163432003","article-title":"The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction","volume":"343","author":"Kim","year":"2000","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cjca.2014.03.013_bib74","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.jacc.2013.03.080","article-title":"Prognostic value of stress cardiac magnetic resonance imaging in patients with known or suspected coronary artery disease: a systematic review and meta-analysis","volume":"62","author":"Lipinski","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2014.03.013_bib75","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1532-429X-12-41","article-title":"Real-time cine and myocardial perfusion with treadmill exercise stress cardiovascular magnetic resonance in patients referred for stress SPECT","volume":"12","author":"Raman","year":"2010","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"key":"10.1016\/j.cjca.2014.03.013_bib76","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1093\/eurheartj\/ehs200","article-title":"Impact of reduction in right ventricular pressure and\/or volume overload by percutaneous pulmonary valve implantation on biventricular response to exercise: an exercise stress real-time CMR study","volume":"33","author":"Lurz","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2014.03.013_bib77","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1002\/jmri.22573","article-title":"Cardiovascular MR dobutamine stress in adult tetralogy of Fallot: disparity between CMR volumetry and flow for cardiovascular function","volume":"33","author":"Valverde","year":"2011","journal-title":"J\u00a0Magn Reson Imaging"},{"key":"10.1016\/j.cjca.2014.03.013_bib78","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1161\/01.CIR.99.6.763","article-title":"Noninvasive diagnosis of ischemia-induced wall motion abnormalities with the use of high-dose dobutamine stress MRI: comparison with dobutamine stress echocardiography","volume":"99","author":"Nagel","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2014.03.013_bib79","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1148\/radiol.2231010924","article-title":"Exercise MR imaging in the assessment of pulmonary regurgitation and biventricular function in patients after tetralogy of fallot repair","volume":"223","author":"Roest","year":"2002","journal-title":"Radiology"}],"container-title":["Canadian Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0828282X14001512?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0828282X14001512?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T09:35:36Z","timestamp":1648632936000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0828282X14001512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":79,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0828282X14001512"],"URL":"https:\/\/doi.org\/10.1016\/j.cjca.2014.03.013","relation":{},"ISSN":["0828-282X"],"issn-type":[{"value":"0828-282X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exercise Testing and Stress Imaging in Valvular Heart Disease","name":"articletitle","label":"Article Title"},{"value":"Canadian Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cjca.2014.03.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}