{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T10:57:55Z","timestamp":1774609075890,"version":"3.50.1"},"reference-count":58,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["onlinecjc.ca","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Cardiology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.cjca.2016.07.509","type":"journal-article","created":{"date-parts":[[2016,7,24]],"date-time":"2016-07-24T08:37:56Z","timestamp":1469349476000},"page":"S374-S381","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"S2","title":["Rehabilitation Therapy in Peripheral Arterial Disease"],"prefix":"10.1016","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6901-7124","authenticated-orcid":false,"given":"Sandeep","family":"Aggarwal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randy D.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ross","family":"Arena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda","family":"Marra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"McBride","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brea","family":"Lamb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5019-8209","authenticated-orcid":false,"given":"Billie-Jean","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Stone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cjca.2016.07.509_bib1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/1358836X0100600i102","article-title":"Peripheral arterial disease\u2014epidemiological aspects","volume":"6","author":"Criqui","year":"2001","journal-title":"Vasc Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib2","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1056\/NEJMra021135","article-title":"Medical progress: exercise training for claudication","volume":"347","author":"Stewart","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib3","series-title":"Current Therapy in Vascular and Endovascular Surgery","first-page":"601","article-title":"Exercise in peripheral arterial disease","author":"Sarraf","year":"2014"},{"key":"10.1016\/j.cjca.2016.07.509_bib4","first-page":"203","article-title":"Arterial dysfunction and functional performance in patients with peripheral artery disease: a review","volume":"16","author":"Coutinho","year":"2011","journal-title":"J\u00a0Vasc Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib5","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2147\/vhrm.2007.3.2.229","article-title":"Epidemiology, classification, and modifiable risk factors of peripheral arterial disease","volume":"3","author":"Shammas","year":"2007","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.cjca.2016.07.509_bib6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1161\/CIR.0000000000000152","article-title":"Heart Disease and Stroke Statistics\u20142015 update: a report from the American Heart Association","volume":"131","author":"Mozaffarian","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2016.07.509_bib7","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0828-282X(09)70021-2","article-title":"Peripheral arterial disease: lack of awareness in Canada","volume":"25","author":"Lovell","year":"2009","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib8","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1177\/1358863X10378376","article-title":"Sensitivity and specificity of the ankle-brachial index to diagnose peripheral artery disease: a structured review","volume":"15","author":"Xu","year":"2010","journal-title":"Vasc Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib9","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1161\/CIRCOUTCOMES.109.930735","article-title":"Vascular hospitalization rates and costs in patients with peripheral artery disease in the United States","volume":"3","author":"Mahoney","year":"2010","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.cjca.2016.07.509_bib10","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.jacc.2005.10.009","article-title":"ACC\/AHA 2005 guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic)","author":"Hirsch","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib11","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.2337\/diacare.26.12.3333","article-title":"Peripheral arterial disease in people with diabetes","volume":"26","author":"Sheedhan","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.cjca.2016.07.509_bib12","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1001\/jama.292.4.453","article-title":"Functional decline in peripheral arterial disease: associations with the ankle brachial and leg symptoms","volume":"292","author":"McDermott","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.cjca.2016.07.509_bib13","unstructured":"Regensteiner JG, Treat-Jacobson D, Walsh ME, et\u00a0al; PARTNERS. The impact of peripheral arterial disease (PAD) on health-related quality of life (HQL). 2002;102:11-400."},{"key":"10.1016\/j.cjca.2016.07.509_bib14","first-page":"381","article-title":"Novel markers of peripheral arterial disease","volume":"14","author":"Khawaja","year":"2009","journal-title":"J\u00a0Vasc Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib15","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1161\/01.CIR.0000160581.58633.8B","article-title":"Peripheral arterial disease","volume":"111","author":"Gornik","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2016.07.509_bib16","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1097\/01.RVI.0000137978.15352.C6","article-title":"Medical treatment of peripheral arterial disease: a comprehensive review","volume":"15","author":"Stoyioglou","year":"2004","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib17","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1001\/jama.284.10.1263","article-title":"Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: The ADMIT study: Arterial Disease Multiple Intervention Trial","volume":"284","author":"Elam","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.cjca.2016.07.509_bib18","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1177\/1358863X14523064","article-title":"Pharmacist influence on prescribing in peripheral arterial disease (PIPER)","volume":"19","author":"Brook-Barclay","year":"2014","journal-title":"Vasc Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib19","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1001\/jama.2009.623","article-title":"Aspirin for the prevention of cardiovascular events in patients with preipheral artery disease; a meta-analysis of randomized trials","volume":"301","author":"Berger","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.cjca.2016.07.509_bib20","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(96)09457-3","article-title":"A\u00a0randomised, blinded trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)","volume":"348","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.cjca.2016.07.509_bib21","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/eurheartj\/ehn534","article-title":"Patients with peripheral arterial disease in the CHARISMA trial","volume":"30","author":"Cacoub","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cjca.2016.07.509_bib22","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1056\/NEJMoa060989","article-title":"Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events","volume":"354","author":"Bhatt","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib23","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jvs.2015.01.051","article-title":"Association of dual-antiplatelet therapy with reduced major adverse cardiovascular events in patients with symptomatic peripheral arterial disease","volume":"62","author":"Armstrong","year":"2015","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib24","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.jvs.2010.04.027","article-title":"Results of the randomized, placebo-controlled clopidogrel and acetylsalicylic acid in bypass surgery for peripheral arterial disease (CASPAR) trial","volume":"52","author":"Belch","year":"2010","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib25","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1016\/j.jacc.2016.03.524","article-title":"Ticagrelor for the prevention of ischemic events after myocardial infarction in patients with peripheral artery disease","volume":"67","author":"Bonaca","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib26","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.jvs.2006.12.054","article-title":"Randomized trial of the effects of cholesterol lowering with simvastatin on peripheral vascular outcomes in 20,536 people with peripheral arterial disease and other high-risk condition high-risk conditions","volume":"45","year":"2007","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib27","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1056\/NEJM200001203420301","article-title":"Effects of an angiotensin-converting enzyme inhibitor, ramipril on cardiovascular events in high-risk patients","volume":"342","year":"2000","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib28","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1161\/CIRCULATIONAHA.110.003954","article-title":"Secondary prevention and mortality in peripheral artery disease: National Health and Nutrition Examination Study, 1999 to 2004","volume":"124","author":"Pande","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2016.07.509_bib29","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1161\/CIRCULATIONAHA.109.881888","article-title":"Exercise rehabilitation in peripheral artery disease: functional impact and mechanism of benefits","volume":"123","author":"Hamburg","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2016.07.509_bib30","first-page":"344","article-title":"Relationship between smoking and cardiovascular risk factors in the development of peripheral arterial disease and coronary artery disease: Edinburgh Artery Study","volume":"20","author":"Price","year":"1999","journal-title":"Eur Soc Cardiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib31","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1177\/000331979905000501","article-title":"Acute reduction in ankle\/brachial index following smoking in chronic smokers with peripheral arterial occlusive disease","volume":"50","author":"Yataco","year":"1999","journal-title":"Angiology"},{"key":"10.1016\/j.cjca.2016.07.509_bib32","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/s11936-013-0231-z","article-title":"Exercise therapy for claudication: latest advances","volume":"15","author":"Mays","year":"2013","journal-title":"Curr Treat Options in Cardiovasc Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib33","first-page":"299","article-title":"Intensive walking exercise for lower extremity peripheral arterial disease: a systemic review and meta-analysis","volume":"7","author":"Lyu","year":"2015","journal-title":"J\u00a0Diabetes"},{"key":"10.1016\/j.cjca.2016.07.509_bib34","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1177\/1538574406296209","article-title":"Benefits of a supervised exercise program after lower limb bypass surgery","volume":"41","author":"Badger","year":"2007","journal-title":"Vasc Endovasc Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib35","first-page":"130","article-title":"Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six month outcomes from the Claudication: exercise versus endoluminal revascularization (CLEVER) study","volume":"125","author":"Murphy","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.cjca.2016.07.509_bib36","first-page":"CD005263","article-title":"Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication","volume":"23","author":"Fokkenrood","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.cjca.2016.07.509_bib37","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.jacc.2014.12.043","article-title":"Supervised exercise, stent revascularization,or medical therapy for claudication due to aortoiliac peripheral artery disease: the CLEVER study","volume":"65","author":"Murphy","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib38","doi-asserted-by":"crossref","first-page":"5998","DOI":"10.3390\/ijerph10115998","article-title":"Twelve-months follow-up of supervised exercise after percutaneous transluminal angioplasty for intermittent claudication:a randomised clinical trial","volume":"10","author":"B\u00f8","year":"2013","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.cjca.2016.07.509_bib39","doi-asserted-by":"crossref","first-page":"7961","DOI":"10.3390\/ijerph110807961","article-title":"Effectiveness of a new exercise program after lower limb arterial blood flow surgery in patients with peripheral arterial disease: a randomized clinical trial","volume":"11","author":"Jakubsevi\u010dien\u0117","year":"2014","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.cjca.2016.07.509_bib40","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/j.jacc.2007.12.034","article-title":"Prognostic value of functional performance for mortality in patients with peripheral artery disease","volume":"51","author":"McDermott","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib41","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1016\/j.jacc.2013.01.060","article-title":"Declining walking impairment questionnaire scores are associated with subsequent increased mortality in peripheral artery disease","volume":"61","author":"Jain","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.cjca.2016.07.509_bib42","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1253\/circj.CJ-08-0141","article-title":"Patients with peripheral artery disease who complete 12-week supervised exercise training program show reduced cardiovascular mortality and morbidity","volume":"73","author":"Sakamoto","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2016.07.509_bib43","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1097\/00008483-200105000-00006","article-title":"Effects of home versus supervised exercise for patients with intermittent claudication","volume":"21","author":"Savage","year":"2001","journal-title":"J\u00a0Cardiopulm Rehabil"},{"key":"10.1016\/j.cjca.2016.07.509_bib44","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1001\/jama.2013.7231","article-title":"Home-based walking exercise intervention in peripheral artery disease: a randomized clinical trial","volume":"310","author":"McDermott","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.cjca.2016.07.509_bib45","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1161\/CIRCULATIONAHA.110.963066","article-title":"Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication","volume":"123","author":"Gardner","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.cjca.2016.07.509_bib46","doi-asserted-by":"crossref","first-page":"983","DOI":"10.2165\/00007256-200434140-00004","article-title":"Optimising exercise training in peripheral arterial disease","volume":"34","author":"Bulmer","year":"2004","journal-title":"Sports Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib47","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s00421-008-0826-3","article-title":"Plantar flexion: an effective training for peripheral arterial disease","volume":"104","author":"Wang","year":"2008","journal-title":"Eur J Appl Pysiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib48","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1001\/jama.2008.962","article-title":"Treadmill exercise and resistance training in patients with peripheral arterial disease with and without intermittent claudication","volume":"301","author":"McDermott","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.cjca.2016.07.509_bib49","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.jvs.2005.08.021","article-title":"Upper- vs lower-limb aerobic exercise rehabilitation in patients with symptomatic peripheral arterial disease: a randomized controlled trial","volume":"42","author":"Zwierska","year":"2005","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib50","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1042\/CS20080688","article-title":"Limb-specific and cross-transfer effects of arm-crank exercise training in patients with symptomatic peripheral arterial disease","volume":"117","author":"Tew","year":"2009","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.cjca.2016.07.509_bib51","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/00005082-200505000-00009","article-title":"Cardiovascular training effect associated with polestriding exercise in patients with peripheral arterial disease","volume":"20","author":"Collins","year":"2005","journal-title":"J\u00a0Cardiovasc Nurs"},{"key":"10.1016\/j.cjca.2016.07.509_bib52","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.ejvs.2014.04.020","article-title":"Significant savings with a stepped care model for treatment of patients with intermittent claudication","volume":"48","author":"Fokkenrood","year":"2014","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib53","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/j.jvs.2008.06.016","article-title":"Cost-effectiveness of endovascular revascularization compared to supervised hospital-based exercise training in patients with intermittent claudication: a randomized controlled trial","volume":"48","author":"Spronk","year":"2008","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib54","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.ejvs.2013.09.005","article-title":"The cost-effectiveness of supervised exercise for the treatment of intermittent claudication","volume":"46","author":"Bermingham","year":"2013","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib55","first-page":"997","article-title":"Canadian Cardiovascular Society Consensus Conference: peripheral arterial disease\u2014executive summary","volume":"21","author":"Abramson","year":"2005","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.cjca.2016.07.509_bib56","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1001\/jamasurg.2016.0415","article-title":"Efficacy of a guideline-recommended risk-reduction program to improve cardiovascular and limb outcomes in patients with peripheral arterial disease","volume":"151","author":"Hussain","year":"2016","journal-title":"JAMA Surg"},{"key":"10.1016\/j.cjca.2016.07.509_bib57","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1191\/1358863x03vm506ra","article-title":"Lower extremity peripheral arterial disease in hospitalized patients with coronary artery disease","volume":"8","author":"Dieter","year":"2003","journal-title":"Vasc Med"},{"key":"10.1016\/j.cjca.2016.07.509_bib58","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1001\/jama.286.11.1317","article-title":"Peripheral arterial disease detection, awareness, and treatment in primary care","volume":"286","author":"Hirsch","year":"2001","journal-title":"JAMA"}],"container-title":["Canadian Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0828282X1630722X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0828282X1630722X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T04:23:39Z","timestamp":1536553419000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0828282X1630722X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":58,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S0828282X1630722X"],"URL":"https:\/\/doi.org\/10.1016\/j.cjca.2016.07.509","relation":{},"ISSN":["0828-282X"],"issn-type":[{"value":"0828-282X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rehabilitation Therapy in Peripheral Arterial Disease","name":"articletitle","label":"Article Title"},{"value":"Canadian Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cjca.2016.07.509","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}