{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T01:35:17Z","timestamp":1768700117736,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T00:00:00Z","timestamp":1686700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022-JCJQ-ZD-097-12"],"award-info":[{"award-number":["2022-JCJQ-ZD-097-12"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022-JCJQ-ZQ-019"],"award-info":[{"award-number":["2022-JCJQ-ZQ-019"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014857","name":"National Natural Science Foundation of China-Guangdong Joint Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014857","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chinese Journal of Traumatology"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.cjtee.2023.06.002","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T17:03:09Z","timestamp":1686848589000},"page":"18-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Calcitonin gene-related peptide inhibits neuronal apoptosis in heatstroke rats via PKA\/p-CREB pathway"],"prefix":"10.1016","volume":"27","author":[{"given":"Jie","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya-Hong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-Jing","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Xiang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Feng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cjtee.2023.06.002_bib1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.7205\/MILMED-D-13-00315","article-title":"Report of 182 cases of exertional heatstroke in the French Armed Forces","volume":"179","author":"Abriat","year":"2014","journal-title":"Mil Med"},{"key":"10.1016\/j.cjtee.2023.06.002_bib2","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1186\/s12872-020-01529-7","article-title":"Protective effects of rolipram on endotoxic cardiac dysfunction via inhibition of the inflammatory response in cardiac fibroblasts","volume":"20","author":"Ji","year":"2020","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.cjtee.2023.06.002_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2020.588400","article-title":"Turning the 'tides on neuropsychiatric diseases: the role of peptides in the prefrontal cortex","volume":"14","author":"Brockway","year":"2020","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.cjtee.2023.06.002_bib4","article-title":"Neuropeptide system regulation of prefrontal cortex circuitry: implications for neuropsychiatric disorders","volume":"16","author":"Casello","year":"2022","journal-title":"Front Neural Circ"},{"key":"10.1016\/j.cjtee.2023.06.002_bib5","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.nrl.2019.03.013","article-title":"Calcitonin gene-related peptide in migraine: from pathophysiology to treatment","volume":"37","author":"Santos-Lasaosa","year":"2022","journal-title":"Neurologia"},{"key":"10.1016\/j.cjtee.2023.06.002_bib6","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1007\/s11064-020-03141-9","article-title":"Exogenous CGRP regulates apoptosis and autophagy to alleviate traumatic brain injury through Akt\/mTOR signalling pathway","volume":"45","author":"Tan","year":"2020","journal-title":"Neurochem Res"},{"key":"10.1016\/j.cjtee.2023.06.002_bib7","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/cns.12696","article-title":"Calcitonin gene-related peptide (CGRP): a novel target for Alzheimer's disease","volume":"23","author":"Singh","year":"2017","journal-title":"CNS Neurosci Ther"},{"key":"10.1016\/j.cjtee.2023.06.002_bib8","first-page":"4935","article-title":"Calcitonin gene-related peptide has protective effect on brain injury induced by heat stroke in rats","volume":"14","author":"Lu","year":"2017","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.cjtee.2023.06.002_bib9","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/j.2040-4603.2015.tb00612.x","article-title":"Heat stroke","volume":"5","author":"Leon","year":"2015","journal-title":"Compr Physiol"},{"key":"10.1016\/j.cjtee.2023.06.002_bib10","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1152\/japplphysiol.00667.2016","article-title":"Unique cytokine and chemokine responses to exertional heat stroke in mice","volume":"122","author":"King","year":"1985","journal-title":"J\u00a0Appl Physiol"},{"key":"10.1016\/j.cjtee.2023.06.002_bib11","doi-asserted-by":"crossref","first-page":"3775","DOI":"10.1002\/jcp.27143","article-title":"Proteomic identification of hippocalcin and its protective role in heatstroke-induced hypothalamic injury in mice","volume":"234","author":"Ji","year":"2019","journal-title":"J\u00a0Cell Physiol"},{"key":"10.1016\/j.cjtee.2023.06.002_bib12","first-page":"570","article-title":"Research progress in the pathogenesis of central nervous system on severe heat stroke","volume":"25","author":"Li","year":"2013","journal-title":"Zhonghua Wei Zhong Bing Ji Jiu Yi Xue"},{"key":"10.1016\/j.cjtee.2023.06.002_bib13","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1111\/head.12656","article-title":"The journey to establish CGRP as a migraine target: a retrospective view","volume":"55","author":"Edvinsson","year":"2015","journal-title":"Headache"},{"key":"10.1016\/j.cjtee.2023.06.002_bib14","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1111\/head.13591","article-title":"CGRP and brain functioning: cautions for migraine treatment","volume":"59","author":"Borkum","year":"2019","journal-title":"Headache"},{"key":"10.1016\/j.cjtee.2023.06.002_bib15","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.3390\/ijms18081788","article-title":"The role of neurogenic inflammation in blood-brain barrier disruption and development of cerebral oedema following acute central nervous system (CNS) injury","volume":"18","author":"Sorby-Adams","year":"2017","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.cjtee.2023.06.002_bib16","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1007\/s11064-020-03141-9","article-title":"Exogenous CGRP regulates apoptosis and autophagy to alleviate traumatic brain injury through Akt\/mTOR signalling pathway","volume":"45","author":"Tian","year":"2020","journal-title":"Neurochem Res"},{"key":"10.1016\/j.cjtee.2023.06.002_bib17","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.jocn.2012.07.006","article-title":"Calcitonin-gene related peptide and cerebral vasospasm","volume":"20","author":"Schebesch","year":"2013","journal-title":"J\u00a0Clin Neurosci"},{"key":"10.1016\/j.cjtee.2023.06.002_bib18","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.pedneo.2015.10.012","article-title":"Calcitonin gene-related peptide downregulates expression of inducible nitride oxide synthase and caspase-3 after intestinal ischemia-reperfusion injury in rats","volume":"57","author":"Luo","year":"2016","journal-title":"Pediatr Neonatol"},{"key":"10.1016\/j.cjtee.2023.06.002_bib19","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1042\/BST0350729","article-title":"Ligand binding and activation of the CGRP receptor","volume":"35","author":"Conner","year":"2007","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.cjtee.2023.06.002_bib20","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s10194-022-01403-1","article-title":"Calcitonin gene-related peptide receptor antagonist BIBN4096BS regulates synaptic transmission in the vestibular nucleus and improves vestibular function via PKC\/ERK\/CREB pathway in an experimental chronic migraine rat model","volume":"23","author":"Tian","year":"2022","journal-title":"J\u00a0Headache Pain"}],"container-title":["Chinese Journal of Traumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1008127523000500?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1008127523000500?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:18:21Z","timestamp":1760883501000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1008127523000500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S1008127523000500"],"URL":"https:\/\/doi.org\/10.1016\/j.cjtee.2023.06.002","relation":{},"ISSN":["1008-1275"],"issn-type":[{"value":"1008-1275","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Calcitonin gene-related peptide inhibits neuronal apoptosis in heatstroke rats via PKA\/p-CREB pathway","name":"articletitle","label":"Article Title"},{"value":"Chinese Journal of Traumatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cjtee.2023.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Chinese Medical Association. Production and hosting by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}