{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T16:09:53Z","timestamp":1787587793195,"version":"build-2736575974"},"reference-count":50,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T00:00:00Z","timestamp":1671753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003176","name":"Ministerio de Educaci\u00f3n, Cultura y Deporte","doi-asserted-by":"publisher","award":["FPU17\/03665"],"award-info":[{"award-number":["FPU17\/03665"]}],"id":[{"id":"10.13039\/501100003176","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003508","name":"Universitat de Val\u00e8ncia","doi-asserted-by":"publisher","award":["UV-INV-PREDOC18F2-886420"],"award-info":[{"award-number":["UV-INV-PREDOC18F2-886420"]}],"id":[{"id":"10.13039\/501100003508","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","contactlensjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contact Lens and Anterior Eye"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.clae.2022.101799","type":"journal-article","created":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T07:27:46Z","timestamp":1672039666000},"page":"101799","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Assessment of condition-induced changes on the ocular surface using novel methods to assess the tear film dynamics and the lipid layer"],"prefix":"10.1016","volume":"46","author":[{"given":"Jos\u00e9","family":"Vicente Garc\u00eda-Marqu\u00e9s","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Talens-Estarelles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Garc\u00eda-L\u00e1zaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Cervi\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clae.2022.101799_b0005","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.jtos.2017.05.001","article-title":"TFOS DEWS II Diagnostic Methodology report","volume":"15","author":"Wolffsohn","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.clae.2022.101799_b0010","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1080\/02713683.2021.1887270","article-title":"An Emerging Method to Assess Tear Film Spread and Dynamics as Possible Tear Film Homeostasis Markers","volume":"46","author":"Garc\u00eda-Marqu\u00e9s","year":"2021","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.clae.2022.101799_b0015","article-title":"Validation of a new objective method to assess lipid layer thickness without the need of an interferometer","author":"Garc\u00eda-Marqu\u00e9s","year":"2021","journal-title":"Graefe\u2019s Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.clae.2022.101799_b0020","first-page":"8","article-title":"Tracking the reflective light particles spreading on the cornea: An emerging assessment for tear film homeostasis","author":"Lai","year":"2019","journal-title":"Transl Vis Sci Technol"},{"key":"10.1016\/j.clae.2022.101799_b0025","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1097\/00003226-200107000-00009","article-title":"Spreading of the tears after a blink: Velocity and stabilization time in healthy eyes","volume":"20","author":"Owens","year":"2001","journal-title":"Cornea"},{"key":"10.1016\/j.clae.2022.101799_b0030","doi-asserted-by":"crossref","first-page":"e1119","DOI":"10.1097\/OPX.0b013e3182644cb7","article-title":"Estimating tear film spread and stability through tear hydrodynamics","volume":"89","author":"Varikooty","year":"2012","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0035","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.jtos.2020.10.001","article-title":"Use of digital displays and ocular surface alterations: A review","volume":"19","author":"Talens-Estarelles","year":"2021","journal-title":"Ocul Surf"},{"key":"10.1016\/j.clae.2022.101799_b0040","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jtos.2017.05.003","article-title":"TFOS DEWS II Epidemiology Report","volume":"15","author":"Stapleton","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.clae.2022.101799_b0045","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.jtos.2017.05.004","article-title":"TFOS DEWS II iatrogenic report","volume":"15","author":"Gomes","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.clae.2022.101799_b0050","article-title":"Tear film stability over a myopia control contact lens compared to a monofocal design","author":"Garc\u00eda-Marqu\u00e9s","year":"2021","journal-title":"Clin Exp Optom"},{"key":"10.1016\/j.clae.2022.101799_b0055","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.jtos.2017.05.006","article-title":"TFOS DEWS II Management and Therapy Report","volume":"15","author":"Jones","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.clae.2022.101799_b0060","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1111\/opo.12987","article-title":"Digital display use and contact lens wear: Effects on dry eye signs and symptoms","volume":"42","author":"Talens-Estarelles","year":"2022","journal-title":"Ophthalmic Physiol Opt"},{"key":"10.1016\/j.clae.2022.101799_b0065","doi-asserted-by":"crossref","DOI":"10.1186\/s12938-017-0373-4","article-title":"A clinical utility assessment of the automatic measurement method of the quality of Meibomian glands","volume":"16","author":"Koprowski","year":"2017","journal-title":"Biomed Eng Online"},{"key":"10.1016\/j.clae.2022.101799_b0070","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1097\/ICL.0000000000000816","article-title":"Online Vs In-person Education: Evaluating the Potential Influence of Teaching Modality on Dry Eye Symptoms and Risk Factors During the COVID-19 Pandemic","volume":"47","author":"Talens-Estarelles","year":"2021","journal-title":"Eye Contact Lens"},{"key":"10.1016\/j.clae.2022.101799_b0075","doi-asserted-by":"crossref","first-page":"85","DOI":"10.5301\/ejo.5000525","article-title":"Change in tear film characteristics in visual display terminal users","volume":"25","author":"Yazici","year":"2014","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.clae.2022.101799_b0080","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/cxo.12210","article-title":"Prevalence of and risk factors for symptomatic dry eye disease in Singapore","volume":"98","author":"Tan","year":"2015","journal-title":"Clin Exp Optom"},{"key":"10.1016\/j.clae.2022.101799_b0085","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.ajo.2013.12.023","article-title":"Dry eye in the beaver dam offspring study: Prevalence, risk factors, and health-related quality of life","volume":"157","author":"Paulsen","year":"2014","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.clae.2022.101799_b0090","first-page":"13","article-title":"The influences of smartphone use on the status of the tear film and ocular surface","author":"Choi","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.clae.2022.101799_b0095","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/467039","article-title":"Ocular Surface and Tear Film Changes in Older Women Working with Computers","author":"Ribelles","year":"2015","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.clae.2022.101799_b0100","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1097\/OPX.0000000000001616","article-title":"How Do Different Digital Displays Affect the Ocular Surface?","volume":"97","author":"Talens-Estarelles","year":"2020","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00421-007-0661-y","article-title":"Ocular surface area and human eye blink frequency during VDU work: The effect of monitor position and task","volume":"103","author":"Nielsen","year":"2008","journal-title":"Eur J Appl Physiol"},{"key":"10.1016\/j.clae.2022.101799_b0110","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3109\/02713683.2010.544442","article-title":"Blink rate, blink amplitude, and tear film integrity during dynamic visual display terminal tasks","volume":"36","author":"Cardona","year":"2011","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.clae.2022.101799_b0115","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/00006324-199603000-00011","article-title":"Tear film lipid layer formation: Implications for contact lens wear","volume":"73","author":"Korb","year":"1996","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0120","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1097\/00006324-199708000-00023","article-title":"A patient questionnaire approach to estimating the prevalence of dry eye symptoms in patients presenting to optometric practices across Canada","volume":"74","author":"Doughty","year":"1997","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0125","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1167\/iovs.10-5780","article-title":"Tear menisci and ocular discomfort during daily contact lens wear in symptomatic wearers","volume":"52","author":"Chen","year":"2011","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0130","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.clae.2015.01.010","article-title":"Assessment of corneal thickness and tear meniscus during contact-lens wear","volume":"38","author":"Del \u00c1guila-Carrasco","year":"2015","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.clae.2022.101799_b0135","doi-asserted-by":"crossref","first-page":"5319","DOI":"10.1167\/iovs.07-1407","article-title":"Rheology of tear film lipid layer spread in normal and aqueous tear-deficient dry eyes","volume":"49","author":"Yokoi","year":"2008","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0140","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/01.opx.0000200681.23663.48","article-title":"Changes in ocular physiology, tear film characteristics, and symptomatology with 18 months silicone hydrogel contact lens wear","volume":"83","author":"Santodomingo-Rubido","year":"2006","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0145","doi-asserted-by":"crossref","unstructured":"Hori Y. Secreted mucins on the ocular surface. Investig Ophthalmol Vis Sci 2018; 59:DES151\u20136. 10.1167\/iovs.17-23623.","DOI":"10.1167\/iovs.17-23623"},{"key":"10.1016\/j.clae.2022.101799_b0150","doi-asserted-by":"crossref","first-page":"17","DOI":"10.2147\/OPTO.S55304","article-title":"European survey of contact lens wearers and eye care professionals on satisfaction with a new water gradient daily disposable contact lens","volume":"6","author":"P\u00e9rez-G\u00f3mez","year":"2014","journal-title":"Clin Optom"},{"key":"10.1016\/j.clae.2022.101799_b0155","doi-asserted-by":"crossref","first-page":"e199","DOI":"10.1097\/OPX.0000000000000541","article-title":"Risk factors for dry eye syndrome: A retrospective case-control study","volume":"92","author":"Yang","year":"2015","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0160","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1016\/j.ophtha.2008.06.022","article-title":"Prevalence of Dry Eye Disease among Japanese Visual Display Terminal Users","volume":"115","author":"Uchino","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.clae.2022.101799_b0165","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.clae.2017.09.015","article-title":"The effect of ageing on the ocular surface parameters","volume":"41","author":"Rico-del-Viejo","year":"2018","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.clae.2022.101799_b0170","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1167\/iovs.08-2458","article-title":"Upper and lower tear menisci on contact lenses","volume":"50","author":"Wang","year":"2009","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0175","doi-asserted-by":"crossref","unstructured":"Kojima T. Contact lens-associated dry eye disease: Recent advances worldwide and in Japan. Investig Ophthalmol Vis Sci 2018;59:DES102\u20138. 10.1167\/iovs.17-23685.","DOI":"10.1167\/iovs.17-23685"},{"key":"10.1016\/j.clae.2022.101799_b0180","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1167\/iovs.05-1392","article-title":"Tear film, contact lens, and patient-related factors associated with contact lens-related dry eye","volume":"47","author":"Nichols","year":"2006","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0185","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.clae.2005.12.004","article-title":"Dryness symptoms among an unselected clinical population with and without contact lens wear","volume":"29","author":"Chalmers","year":"2006","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.clae.2022.101799_b0190","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/j.jcrs.2007.06.019","article-title":"Role of the tear film in the optical quality of the human eye","volume":"33","author":"Mont\u00e9s-Mic\u00f3","year":"2007","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.clae.2022.101799_b0195","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.jcrs.2009.12.044","article-title":"Optical quality after instillation of eyedrops in dry-eye syndrome","volume":"36","author":"Mont\u00e9s-Mic\u00f3","year":"2010","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.clae.2022.101799_b0200","doi-asserted-by":"crossref","first-page":"e303","DOI":"10.1097\/OPX.0000000000000490","article-title":"Intraocular scattering after instillation of diquafosol ophthalmic solution","volume":"92","author":"Kobashi","year":"2015","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2022.101799_b0205","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1097\/ICO.0000000000000456","article-title":"Effect of Rebamipide Ophthalmic Suspension on Intraocular Light Scattering for Dry Eye after Corneal Refractive Surgery","volume":"34","author":"Igarashi","year":"2015","journal-title":"Cornea"},{"key":"10.1016\/j.clae.2022.101799_b0210","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.jcrs.2012.02.040","article-title":"Effect of lubricating eyedrops on ocular light scattering as a measure of vision quality in patients with dry eye","volume":"38","author":"Diaz-Valle","year":"2012","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.clae.2022.101799_b0215","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1016\/j.jfo.2017.12.001","article-title":"Comparison of objective optical quality measured by double-pass aberrometry in patients with moderate dry eye: Normal saline vs. artificial tears: A pilot study","volume":"41","author":"Vandermeer","year":"2018","journal-title":"J Fr Ophtalmol"},{"key":"10.1016\/j.clae.2022.101799_b0220","doi-asserted-by":"crossref","first-page":"819","DOI":"10.2147\/OPTH.S162233","article-title":"Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses","volume":"12","author":"Schafer","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.clae.2022.101799_b0225","doi-asserted-by":"crossref","first-page":"783","DOI":"10.2147\/OPTH.S13773","article-title":"Systane\u00ae lubricant eye drops in the management of ocular dryness","volume":"5","author":"Benelli","year":"2011","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.clae.2022.101799_b0230","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1080\/02713683.2020.1849733","article-title":"Efficacy and Safety of Sodium Hyaluronate\/chondroitin Sulfate Preservative-free Ophthalmic Solution in the Treatment of Dry Eye: A Clinical Trial","volume":"46","author":"Belalc\u00e1zar-Rey","year":"2021","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.clae.2022.101799_b0235","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.clae.2017.09.013","article-title":"Tear lipid supplement prophylaxis against dry eye in adverse environments","volume":"41","author":"Gokul","year":"2018","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.clae.2022.101799_b0240","doi-asserted-by":"crossref","DOI":"10.3390\/life12081177","article-title":"The Effects of Soft Contact Lens Wear on The Tear Film and Meibomian Gland Drop-Out and Visibility","volume":"12","author":"Garc\u00eda-Marqu\u00e9s","year":"2022","journal-title":"Life"},{"key":"10.1016\/j.clae.2022.101799_b0245","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1001\/archopht.1995.01100020037025","article-title":"Effects of Ocular Surface Area and Blink Rate on Tear Dynamics","volume":"113","author":"Tsubota","year":"1995","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.clae.2022.101799_b0250","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1444-0938.2007.00136.x","article-title":"The effect of vertical gaze position on ocular tear film stability","volume":"90","author":"Pansell","year":"2007","journal-title":"Clin Exp Optom"}],"container-title":["Contact Lens and Anterior Eye"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1367048422002752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1367048422002752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T01:21:44Z","timestamp":1761268904000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1367048422002752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S1367048422002752"],"URL":"https:\/\/doi.org\/10.1016\/j.clae.2022.101799","relation":{},"ISSN":["1367-0484"],"issn-type":[{"value":"1367-0484","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessment of condition-induced changes on the ocular surface using novel methods to assess the tear film dynamics and the lipid layer","name":"articletitle","label":"Article Title"},{"value":"Contact Lens and Anterior Eye","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clae.2022.101799","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Ltd on behalf of British Contact Lens Association.","name":"copyright","label":"Copyright"}],"article-number":"101799"}}