{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:29:56Z","timestamp":1776904196530,"version":"3.51.2"},"reference-count":20,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:00:00Z","timestamp":1709942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","contactlensjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contact Lens and Anterior Eye"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.clae.2024.102145","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T13:26:17Z","timestamp":1710163577000},"page":"102145","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Severe ulcerative keratopathy following implantation of an acellular porcine corneal stromal lenticule in a patient with keratoconus"],"prefix":"10.1016","volume":"47","author":[{"given":"Tim","family":"Berger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"Schl\u00f6tzer-Schrehardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fidelis","family":"Flockerzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loay","family":"Daas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elias","family":"Flockerzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clae.2024.102145_b0005","series-title":"Corneal Transplantation","first-page":"67","article-title":"The Penetrating Keratoplasty (PKP): A Century of Success","author":"Seitz","year":"2016"},{"key":"10.1016\/j.clae.2024.102145_b0010","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1001\/jamaophthalmol.2015.4776","article-title":"Global survey of corneal transplantation and eye banking","volume":"134","author":"Gain","year":"2016","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.clae.2024.102145_b0015","doi-asserted-by":"crossref","unstructured":"Flockerzi E, Turner C, Seitz B, Collaborators GSG. Descemet\u2019s membrane endothelial keratoplasty is the predominant keratoplasty procedure in Germany since 2016: a report of the DOG-section cornea and its keratoplasty registry. Br J Ophthalmol 2023. epub ahead of print. doi: 10.1136\/bjo-2022-323162.","DOI":"10.1136\/bjo-2022-323162"},{"key":"10.1016\/j.clae.2024.102145_b0020","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/xen.12082","article-title":"Corneal blindness and xenotransplantation","volume":"21","author":"Lamm","year":"2014","journal-title":"Xenotransplantation"},{"key":"10.1016\/j.clae.2024.102145_b0025","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/MOT.0b013e328344870c","article-title":"Xenocorneal transplantation","volume":"16","author":"Kim","year":"2011","journal-title":"Curr Opin Organ Transplant"},{"key":"10.1016\/j.clae.2024.102145_b0030","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1399-3089.2010.00608.x","article-title":"The immunology of corneal xenotransplantation: a review of the literature","volume":"17","author":"Hara","year":"2010","journal-title":"Xenotransplantation"},{"key":"10.1016\/j.clae.2024.102145_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2020.100876","article-title":"Corneal xenotransplantation: where are we standing?","volume":"80","author":"Yoon","year":"2021","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.clae.2024.102145_b0040","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/ICO.0b013e3181f237ef","article-title":"Xenotransplantation-the future of corneal transplantation?","volume":"30","author":"Hara","year":"2011","journal-title":"Cornea"},{"key":"10.1016\/j.clae.2024.102145_b0045","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/bmb\/ldx043","article-title":"Xenotransplantation - the current status and prospects","volume":"125","author":"Cooper","year":"2018","journal-title":"Br Med Bull"},{"key":"10.1016\/j.clae.2024.102145_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/xen.12490","article-title":"Xenotransplantation in China: present status","volume":"26","author":"Wang","year":"2019","journal-title":"Xenotransplantation"},{"key":"10.1016\/j.clae.2024.102145_b0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/xen.12566","article-title":"Healing characteristics of acellular porcine corneal stroma following therapeutic keratoplasty","volume":"27","author":"Li","year":"2020","journal-title":"Xenotransplantation"},{"key":"10.1016\/j.clae.2024.102145_b0060","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/s41587-022-01408-w","article-title":"Bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts","volume":"41","author":"Rafat","year":"2023","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.clae.2024.102145_b0065","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1111\/ajt.13096","article-title":"Lamellar keratoplasty treatment of fungal corneal ulcers with acellular porcine corneal stroma","volume":"15","author":"Zhang","year":"2015","journal-title":"Am J Transplant"},{"key":"10.1016\/j.clae.2024.102145_b0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/xen.12509","article-title":"Short-term results of acellular porcine corneal stroma keratoplasty for herpes simplex keratitis","volume":"26","author":"Zheng","year":"2019","journal-title":"Xenotransplantation"},{"key":"10.1016\/j.clae.2024.102145_b0075","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/aos.14665","article-title":"Corneal calcification of acellular porcine corneal stroma following lamellar keratoplasty","volume":"100","author":"Li","year":"2022","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.clae.2024.102145_b0080","doi-asserted-by":"crossref","first-page":"1902491","DOI":"10.1002\/adfm.201902491","article-title":"Protectively Decellularized porcine cornea versus human donor cornea for Lamellar transplantation","volume":"29","author":"Shi","year":"2019","journal-title":"Adv Funct Mater"},{"key":"10.1016\/j.clae.2024.102145_b0085","series-title":"Modern Keratoplasty. Essentials in Ophthalmology","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/978-3-031-32408-6_11","article-title":"Excimer laser-assisted keratoplasty: penetrating keratoplasty \u201cExcimer-PKP\u201d and deep anterior lamellar keratoplasty \u201cExcimer-DALK\u201d","author":"Daas","year":"2023"},{"key":"10.1016\/j.clae.2024.102145_b0090","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1159\/000305147","article-title":"Steady state levels of glucose in the different layers of the cornea, aqueous humor, blood and tears in vivo","volume":"154","author":"Reim","year":"1967","journal-title":"Ophthalmologica"},{"key":"10.1016\/j.clae.2024.102145_b0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/xen.12338","article-title":"Comprehensive evaluation of decellularized porcine corneal after clinical transplantation","volume":"24","author":"Shi","year":"2017","journal-title":"Xenotransplantation"},{"key":"10.1016\/j.clae.2024.102145_b0100","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/S0161-6420(99)90265-8","article-title":"Nonmechanical corneal trephination with the excimer laser improves outcome after penetrating keratoplasty","volume":"106","author":"Seitz","year":"1999","journal-title":"Ophthalmology"}],"container-title":["Contact Lens and Anterior Eye"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1367048424000328?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1367048424000328?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T18:58:04Z","timestamp":1718477884000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1367048424000328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S1367048424000328"],"URL":"https:\/\/doi.org\/10.1016\/j.clae.2024.102145","relation":{},"ISSN":["1367-0484"],"issn-type":[{"value":"1367-0484","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Severe ulcerative keratopathy following implantation of an acellular porcine corneal stromal lenticule in a patient with keratoconus","name":"articletitle","label":"Article Title"},{"value":"Contact Lens and Anterior Eye","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clae.2024.102145","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd on behalf of British Contact Lens Association.","name":"copyright","label":"Copyright"}],"article-number":"102145"}}