{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T01:04:05Z","timestamp":1768611845656,"version":"3.49.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","contactlensjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contact Lens and Anterior Eye"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.clae.2025.102512","type":"journal-article","created":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T14:05:55Z","timestamp":1757772355000},"page":"102512","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dehydration kinetics of soft contact lenses: The hidden impact of early wear"],"prefix":"10.1016","volume":"49","author":[{"given":"Silvia","family":"Tavazzi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Galli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Maspero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia Carlotta","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Zeri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3103-740X","authenticated-orcid":false,"given":"Erika","family":"Ponzini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clae.2025.102512_b0005","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/00006324-199003000-00010","article-title":"In vivo dehydration of disposable (Acuvue) contact lenses","volume":"67","author":"Brennan","year":"1990","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2025.102512_b0010","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1097\/00006324-199910000-00021","article-title":"Hydrogel lens dehydration and subjective comfort and dryness ratings in symptomatic and asymptomatic contact lens wearers","volume":"76","author":"Fonn","year":"1999","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.clae.2025.102512_b0015","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/cxo.12487","article-title":"Contact lens wear is intrinsically inflammatory","volume":"100","author":"Efron","year":"2017","journal-title":"Clin Exp Optom"},{"key":"10.1016\/j.clae.2025.102512_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2022.109083","article-title":"Viscoelastic properties of the human tear film","volume":"219","author":"Recchioni","year":"2022","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.clae.2025.102512_b0025","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1002\/jbm.b.33278","article-title":"Wear effects on microscopic morphology and hyaluronan uptake in siloxane-hydrogel contact lenses","volume":"103","author":"Tavazzi","year":"2015","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.clae.2025.102512_b0030","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1002\/jbm.b.32901","article-title":"Surface properties and wear performances of siloxane-hydrogel contact lenses","volume":"101","author":"Bettuelli","year":"2013","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.clae.2025.102512_b0035","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jtos.2023.04.010","article-title":"TFOS lifestyle: impact of contact lenses on the ocular surface","volume":"29","author":"Jones","year":"2023","journal-title":"Ocul Surf"},{"key":"10.1016\/j.clae.2025.102512_b0040","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.clae.2004.08.003","article-title":"Water properties of soft contact lens materials","volume":"27","author":"Tranoudis","year":"2004","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.clae.2025.102512_b0045","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1167\/iovs.13-13212","article-title":"The TFOS international workshop on contact lens discomfort: executive summary","volume":"54","author":"Nichols","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.clae.2025.102512_b0050","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/jbm.b.30824","article-title":"Qualitative and quantitative characterization of the in vitro dehydration process of hydrogel contact lenses","volume":"83B","author":"Gonz\u00e1lez-M\u00e9ijome","year":"2007","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.clae.2025.102512_b0055","doi-asserted-by":"crossref","first-page":"7870","DOI":"10.1038\/s41598-024-55937-2","article-title":"In-vitro dehydration kinetics coefficient of Kalifilcon a and other contact lens materials","volume":"14","author":"Ponzini","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.clae.2025.102512_b0060","article-title":"Dehydration and surface friction of Kalifilcon a and Senofilcon a contact lenses","volume":"47","author":"Ponzini","year":"2024","journal-title":"Nuovo Cimento Della Soc Ital Fis C"},{"key":"10.1016\/j.clae.2025.102512_b0065","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/pen.760200103","article-title":"Sorption and transport in glassy polymers\u2013a review","volume":"20","author":"Frisch","year":"1980","journal-title":"Polym Eng Sci"},{"key":"10.1016\/j.clae.2025.102512_b0070","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3390\/polym12010138","article-title":"A comprehensive review on water diffusion in polymers focusing on the polymer\u2013metal interface combination","volume":"12","author":"Yang","year":"2020","journal-title":"Polymers"},{"key":"10.1016\/j.clae.2025.102512_b0075","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1046\/j.1475-1313.1995.9500004w.x","article-title":"Dehydration, lens movement and dryness ratings of hydrogel contact lenses","volume":"15","author":"Pritchard","year":"1995","journal-title":"Ophthalmic Physiol Opt"},{"key":"10.1016\/j.clae.2025.102512_b0080","unstructured":"Refojo MF. Tear evaporation considerations and contact lens wear. Consid. Contact Lens Use Adverse Cond. Proc. Symp., National Academies Press (US); 1991."},{"issue":"Suppl 2","key":"10.1016\/j.clae.2025.102512_b0085","doi-asserted-by":"crossref","first-page":"S233","DOI":"10.1097\/ICL.0000000000000441","article-title":"Comfort, ocular dryness, and equilibrium water content changes of daily disposable contact lenses","volume":"44","author":"Insua Pereira","year":"2018","journal-title":"Eye Contact Lens"},{"key":"10.1016\/j.clae.2025.102512_b0090","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.clae.2012.10.071","article-title":"Clinical performance and \u201cex vivo\u201d dehydration of silicone hydrogel contact lenses with two new multipurpose solutions","volume":"36","author":"Gonz\u00e1lez-M\u00e9ijome","year":"2013","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.clae.2025.102512_b0095","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0168-3659(87)90034-4","article-title":"A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs","volume":"5","author":"Ritger","year":"1987","journal-title":"J Control Release"},{"key":"10.1016\/j.clae.2025.102512_b0100","unstructured":"Krysztofiak K, Szyczewski A. Study of dehydration and water states in new and worn soft contact lens materials. Opt Appl 22014 ISSN 1429-7507 2014. https:\/\/doi.org\/10.5277\/OA140206."},{"key":"10.1016\/j.clae.2025.102512_b0105","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1167\/tvst.10.8.11","article-title":"Effects of temperature and blinking on contact lens dehydration of contemporary soft lens materials using an in vitro blink model","volume":"10","author":"Chan","year":"2021","journal-title":"Transl Vis Sci Technol"},{"key":"10.1016\/j.clae.2025.102512_b0110","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0141-7037(89)80017-5","article-title":"A predictive model for dehydration of a hydrogel contact lens in the eye","volume":"12","author":"Fatt","year":"1989","journal-title":"J Br Contact Lens Assoc"},{"key":"10.1016\/j.clae.2025.102512_b0115","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.clae.2012.07.008","article-title":"Contact lenses and the rate of evaporation measured in vitro; the influence of wear, squalene and wax","volume":"35","author":"Vishnubhatla","year":"2012","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.clae.2025.102512_b0120","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.3390\/pharmaceutics14102188","article-title":"Contact lens wear induces alterations of lactoferrin functionality in human tears","volume":"14","author":"Ponzini","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.clae.2025.102512_b0125","article-title":"Lactoferrin as a biomarker of ocular diseases and contact lens discomfort","volume":"46","author":"Ponzini","year":"2023","journal-title":"Nuovo Cimento Della Soc Ital Fis C"},{"key":"10.1016\/j.clae.2025.102512_b0130","doi-asserted-by":"crossref","first-page":"4845","DOI":"10.1016\/j.polymer.2005.03.084","article-title":"Glass-transition temperatures for soft-contact-lens materials. Dependence on water content","volume":"46","author":"Fornasiero","year":"2005","journal-title":"Polymer"},{"key":"10.1016\/j.clae.2025.102512_b0135","series-title":"Sorption\/desorption properties of water vapour in poly(2-hydroxyethyl methacrylate): 2","author":"Sun","year":"1996"},{"key":"10.1016\/j.clae.2025.102512_b0140","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1021\/la026719x","article-title":"Effect of equilibrium bulk water content on the humidity-dependent surface mechanical properties of hydrophilic contact lenses studied by atomic force microscopy","volume":"19","author":"Koffas","year":"2003","journal-title":"Langmuir"}],"container-title":["Contact Lens and Anterior Eye"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1367048425001468?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1367048425001468?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T13:37:44Z","timestamp":1768570664000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1367048425001468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S1367048425001468"],"URL":"https:\/\/doi.org\/10.1016\/j.clae.2025.102512","relation":{},"ISSN":["1367-0484"],"issn-type":[{"value":"1367-0484","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dehydration kinetics of soft contact lenses: The hidden impact of early wear","name":"articletitle","label":"Article Title"},{"value":"Contact Lens and Anterior Eye","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clae.2025.102512","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd on behalf of British Contact Lens Association.","name":"copyright","label":"Copyright"}],"article-number":"102512"}}