{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:06:33Z","timestamp":1789387593872,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinical-breast-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Breast Cancer"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.clbc.2019.01.013","type":"journal-article","created":{"date-parts":[[2019,2,10]],"date-time":"2019-02-10T09:24:55Z","timestamp":1549790695000},"page":"208-215","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":68,"title":["Axillary Lymph Node Tattooing and Targeted Axillary Dissection in Breast Cancer Patients Who Presented as cN+ Before Neoadjuvant Chemotherapy and Became cN0 After Treatment"],"prefix":"10.1016","volume":"19","author":[{"given":"Ioannis","family":"Natsiopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Intzes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Triantafyllos","family":"Liappis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Zarampoukas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Zarampoukas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Zacharopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Papazisis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clbc.2019.01.013_bib1","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1200\/JOP.2016.019992","article-title":"Sentinel lymph node biopsy for patients with early-stage breast cancer: 2016 American Society of Clinical Oncology clinical practice guideline update summary","volume":"13","author":"Lyman","year":"2017","journal-title":"J\u00a0Oncol Pract"},{"key":"10.1016\/j.clbc.2019.01.013_bib2","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1200\/JCO.2013.54.1177","article-title":"Sentinel lymph node biopsy for patients with early-stage breast cancer: American Society of Clinical Oncology clinical practice guideline update","volume":"32","author":"Lyman","year":"2014","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib3","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1001\/jama.2011.90","article-title":"Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial","volume":"305","author":"Giuliano","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.clbc.2019.01.013_bib4","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1470-2045(13)70035-4","article-title":"Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial","volume":"14","author":"Galimberti","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib5","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S1470-2045(14)70460-7","article-title":"Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial","volume":"15","author":"Donker","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib6","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/bjs.5209","article-title":"Meta-analysis of sentinel lymph node biopsy after preoperative chemotherapy in patients with breast cancer","volume":"93","author":"Xing","year":"2006","journal-title":"Br J Surg"},{"key":"10.1016\/j.clbc.2019.01.013_bib7","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/jso.21911","article-title":"The feasibility and accuracy of sentinel lymph node biopsy in clinically node-negative patients after neoadjuvant chemotherapy for breast cancer\u2013a systematic review and meta-analysis","volume":"104","author":"Tan","year":"2011","journal-title":"J\u00a0Surg Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib8","doi-asserted-by":"crossref","first-page":"3124","DOI":"10.1016\/j.ejca.2009.08.001","article-title":"Accuracy of sentinel node biopsy after neoadjuvant chemotherapy in breast cancer patients: a systematic review","volume":"45","author":"van Deurzen","year":"2009","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.clbc.2019.01.013_bib10","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1001\/jama.2013.278932","article-title":"Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: the ACOSOG Z1071 (Alliance) clinical trial","volume":"310","author":"Boughey","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.clbc.2019.01.013_bib11","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S1470-2045(13)70166-9","article-title":"Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study","volume":"14","author":"Kuehn","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib12","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1200\/JCO.2014.55.7827","article-title":"Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study","volume":"33","author":"Boileau","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib13","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1097\/SLA.0000000000000558","article-title":"Marking axillary lymph nodes with radioactive iodine seeds for axillary staging after neoadjuvant systemic treatment in breast cancer patients: the MARI procedure","volume":"261","author":"Donker","year":"2015","journal-title":"Ann Surg"},{"key":"10.1016\/j.clbc.2019.01.013_bib14","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1200\/JCO.2015.64.0094","article-title":"Improved axillary evaluation following neoadjuvant therapy for patients with node-positive breast cancer using selective evaluation of clipped nodes: implementation of targeted axillary dissection","volume":"34","author":"Caudle","year":"2016","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib15","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1245\/s10434-014-4034-6","article-title":"Initial results with preoperative tattooing of biopsied axillary lymph nodes and correlation to sentinel lymph nodes in breast cancer patients","volume":"22","author":"Choy","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib16","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.2214\/AJR.16.16545","article-title":"Radiologic mapping for targeted axillary dissection: needle biopsy to excision","volume":"207","author":"Shin","year":"2016","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.clbc.2019.01.013_bib17","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1159\/000486388","article-title":"Using a new marker clip system in breast cancer: Tumark Vision Clip - feasibility testing in everyday clinical practice","volume":"13","author":"Ruland","year":"2018","journal-title":"Breast Care (Basel)"},{"key":"10.1016\/j.clbc.2019.01.013_bib18","doi-asserted-by":"crossref","first-page":"646","DOI":"10.2214\/AJR.07.2460","article-title":"Cortical morphologic features of axillary lymph nodes as a predictor of metastasis in breast cancer: in\u00a0vitro sonographic study","volume":"191","author":"Bedi","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.clbc.2019.01.013_bib19","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.rcl.2010.06.010","article-title":"Regional lymph node staging in breast cancer: the increasing role of imaging and ultrasound-guided axillary lymph node fine needle aspiration","volume":"48","author":"Mainiero","year":"2010","journal-title":"Radiol Clin North Am"},{"key":"10.1016\/j.clbc.2019.01.013_bib20","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0016-5107(02)70035-7","article-title":"Tattoo of colonic neoplasms in 113 patients with a new sterile carbon compound","volume":"56","author":"Askin","year":"2002","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.clbc.2019.01.013_bib21","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1007\/s00268-007-9082-7","article-title":"Tumor localization for laparoscopic colorectal surgery","volume":"31","author":"Cho","year":"2007","journal-title":"World J Surg"},{"key":"10.1016\/j.clbc.2019.01.013_bib22","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1200\/JCO.1997.15.7.2483","article-title":"Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18","volume":"15","author":"Fisher","year":"1997","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib23","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.ctrv.2014.05.001","article-title":"Impact of neoadjuvant single or dual HER2 inhibition and chemotherapy backbone upon pathological complete response in operable and locally advanced breast cancer: sensitivity analysis of randomized trials","volume":"40","author":"Bria","year":"2014","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.clbc.2019.01.013_bib24","doi-asserted-by":"crossref","first-page":"9304","DOI":"10.1200\/JCO.2005.02.5023","article-title":"Outcome after pathologic complete eradication of cytologically proven breast cancer axillary node metastases following primary chemotherapy","volume":"23","author":"Hennessy","year":"2005","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib25","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1002\/cncr.25152","article-title":"Cytologically proven axillary lymph node metastases are eradicated in patients receiving preoperative chemotherapy with concurrent trastuzumab for HER2-positive breast cancer","volume":"116","author":"Dominici","year":"2010","journal-title":"Cancer"},{"key":"10.1016\/j.clbc.2019.01.013_bib26","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1093\/annonc\/mdt182","article-title":"Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA)","volume":"24","author":"Schneeweiss","year":"2013","journal-title":"Ann Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib27","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.amjsurg.2016.07.018","article-title":"Is sentinel lymph node biopsy a viable alternative to complete axillary dissection following neoadjuvant chemotherapy in women with node-positive breast cancer at diagnosis? An updated meta-analysis involving 3,398 patients","volume":"212","author":"El Hage Chehade","year":"2016","journal-title":"Am J Surg"},{"key":"10.1016\/j.clbc.2019.01.013_bib28","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1002\/bjs.10986","article-title":"Meta-analysis of sentinel lymph node biopsy after neoadjuvant chemotherapy in patients with initial biopsy-proven node-positive breast cancer","volume":"105","author":"Tee","year":"2018","journal-title":"Br J Surg"},{"key":"10.1016\/j.clbc.2019.01.013_bib29","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1245\/s10434-015-5052-8","article-title":"Axillary staging after neoadjuvant chemotherapy for breast cancer: a pilot study combining sentinel lymph node biopsy with radioactive seed localization of pre-treatment positive axillary lymph nodes","volume":"23","author":"Diego","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib30","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1245\/s10434-015-4527-y","article-title":"Improving the accuracy of axillary lymph node surgery in breast cancer with ultrasound-guided wire localization of biopsy proven metastatic lymph nodes","volume":"22","author":"Plecha","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clbc.2019.01.013_bib31","doi-asserted-by":"crossref","first-page":"801","DOI":"10.4143\/crt.2017.210","article-title":"Feasibility of charcoal tattooing of cytology-proven metastatic axillary lymph node at diagnosis and sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer patients","volume":"50","author":"Park","year":"2018","journal-title":"Cancer Res Treat"},{"key":"10.1016\/j.clbc.2019.01.013_bib32","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/s12885-016-2137-0","article-title":"The combination of blue dye and radioisotope versus radioisotope alone during sentinel lymph node biopsy for breast cancer: a systematic review","volume":"16","author":"He","year":"2016","journal-title":"BMC Cancer"},{"key":"10.1016\/j.clbc.2019.01.013_bib33","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s10549-015-3280-z","article-title":"Efficacy of physical examination, ultrasound, and ultrasound combined with fine-needle aspiration for axilla staging of primary breast cancer","volume":"149","author":"Feng","year":"2015","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.clbc.2019.01.013_bib34","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00268-012-1788-5","article-title":"Clinical assessment of axillary lymph nodes and tumor size in breast cancer compared with histopathological examination: a population-based analysis of 2,537 women","volume":"37","author":"Majid","year":"2013","journal-title":"World J Surg"},{"key":"10.1016\/j.clbc.2019.01.013_bib35","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/SLA.0b013e31821f1564","article-title":"Preoperative ultrasound-guided needle biopsy of axillary nodes in invasive breast cancer: meta-analysis of its accuracy and utility in staging the axilla","volume":"254","author":"Houssami","year":"2011","journal-title":"Ann Surg"}],"container-title":["Clinical Breast Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820918308450?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820918308450?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:17:53Z","timestamp":1761513473000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526820918308450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S1526820918308450"],"URL":"https:\/\/doi.org\/10.1016\/j.clbc.2019.01.013","relation":{},"ISSN":["1526-8209"],"issn-type":[{"value":"1526-8209","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Axillary Lymph Node Tattooing and Targeted Axillary Dissection in Breast Cancer Patients Who Presented as cN+ Before Neoadjuvant Chemotherapy and Became cN0 After Treatment","name":"articletitle","label":"Article Title"},{"value":"Clinical Breast Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clbc.2019.01.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}