{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:25:15Z","timestamp":1791897915089,"version":"4.3.4"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Stony Brook University School of Medicine"}],"content-domain":{"domain":["clinical-breast-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Breast Cancer"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.clbc.2019.06.006","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T22:38:25Z","timestamp":1561502305000},"page":"68-79.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["MRI Volume Changes of Axillary Lymph Nodes as Predictor of Pathologic Complete Responses to Neoadjuvant Chemotherapy in Breast Cancer"],"prefix":"10.1016","volume":"20","author":[{"given":"Renee F.","family":"Cattell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J.","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline B.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashima","family":"Muttreja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Dacosta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haifang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea","family":"Baer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Clouston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxanne","family":"Palermo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cliff","family":"Bernstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jules A.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim Q.","family":"Duong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clbc.2019.06.006_bib1","first-page":"439","article-title":"Breast cancer statistics, 2017, racial disparity in mortality by state","volume":"67","author":"DeSantis","year":"2017","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.clbc.2019.06.006_bib2","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ejrad.2017.01.030","article-title":"Cross-sectional imaging to evaluate the extent of regional nodal disease in breast cancer patients undergoing neoadjuvant systemic therapy","volume":"89","author":"Anderson","year":"2017","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.clbc.2019.06.006_bib3","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.clbc.2014.09.012","article-title":"Disease-free survival according to the use of postmastectomy radiation therapy after neoadjuvant chemotherapy","volume":"15","author":"Nagar","year":"2015","journal-title":"Clin Breast Cancer"},{"key":"10.1016\/j.clbc.2019.06.006_bib4","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1200\/JCO.2007.15.0235","article-title":"Preoperative chemotherapy: updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27","volume":"26","author":"Rastogi","year":"2008","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clbc.2019.06.006_bib5","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s00259-017-3823-0","article-title":"Added value of dedicated axillary hybrid 18F-FDG PET\/MRI for improved axillary nodal staging in clinically node-positive breast cancer patients: a feasibility study","volume":"45","author":"van Nijnatten","year":"2018","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.clbc.2019.06.006_bib6","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1007\/s00330-017-5005-7","article-title":"Preoperative prediction of sentinel lymph node metastasis in breast cancer based on radiomics of T2-weighted fat-suppression and diffusion-weighted MRI","volume":"28","author":"Dong","year":"2018","journal-title":"Eur Radiol"},{"key":"10.1016\/j.clbc.2019.06.006_bib7","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.crad.2017.09.005","article-title":"Diagnostic performance of gadofosveset-enhanced axillary MRI for nodal (re)staging in breast cancer patients: results of a validation study","volume":"73","author":"van Nijnatten","year":"2018","journal-title":"Clin Radiol"},{"key":"10.1016\/j.clbc.2019.06.006_bib8","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1148\/radiol.2017170180","article-title":"Imaging neoadjuvant therapy response in breast cancer","volume":"285","author":"Fowler","year":"2017","journal-title":"Radiology"},{"key":"10.1016\/j.clbc.2019.06.006_bib9","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1148\/radiol.12110748","article-title":"Locally advanced breast cancer: MR imaging for prediction of response to neoadjuvant chemotherapy--results from ACRIN 6657\/I-SPY TRIAL","volume":"263","author":"Hylton","year":"2012","journal-title":"Radiology"},{"key":"10.1016\/j.clbc.2019.06.006_bib10","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.clbc.2016.11.004","article-title":"Magnetic resonance imaging for axillary breast cancer metastasis in the neoadjuvant setting: a prospective study","volume":"17","author":"Mattingly","year":"2017","journal-title":"Clin Breast Cancer"},{"key":"10.1016\/j.clbc.2019.06.006_bib11","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1148\/radiol.2015150013","article-title":"Neoadjuvant chemotherapy for breast cancer: functional tumor volume by MR imaging predicts recurrence-free survival-results from the ACRIN 6657\/CALGB 150007 I-SPY 1 TRIAL","volume":"279","author":"Hylton","year":"2016","journal-title":"Radiology"},{"key":"10.1016\/j.clbc.2019.06.006_bib12","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1007\/s10278-013-9622-7","article-title":"The Cancer Imaging Archive (TCIA): maintaining and operating a public information repository","volume":"26","author":"Clark","year":"2013","journal-title":"J\u00a0Digit Imaging"},{"key":"10.1016\/j.clbc.2019.06.006_bib13","author":"Newitt"},{"key":"10.1016\/j.clbc.2019.06.006_bib14","doi-asserted-by":"crossref","first-page":"3823","DOI":"10.1245\/s10434-013-3038-y","article-title":"Clinically meaningful tumor reduction rates vary by prechemotherapy MRI phenotype and tumor subtype in the I-SPY 1 TRIAL (CALGB 150007\/150012; ACRIN 6657)","volume":"20","author":"Mukhtar","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clbc.2019.06.006_bib15","doi-asserted-by":"crossref","first-page":"378","DOI":"10.18383\/j.tom.2016.00247","article-title":"Effect of MR imaging contrast thresholds on prediction of neoadjuvant chemotherapy response in breast cancer subtypes: a subgroup analysis of the ACRIN 6657\/I-SPY 1 TRIAL","volume":"2","author":"Li","year":"2016","journal-title":"Tomography"},{"key":"10.1016\/j.clbc.2019.06.006_bib16","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","author":"Benjamini","year":"1995","journal-title":"J\u00a0R Stat Soc"},{"key":"10.1016\/j.clbc.2019.06.006_bib17","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1007\/s00330-016-4565-2","article-title":"Investigating the prediction value of multiparametric magnetic resonance imaging at 3 T in response to neoadjuvant chemotherapy in breast cancer","volume":"27","author":"Minarikova","year":"2017","journal-title":"Eur Radiol"},{"key":"10.1016\/j.clbc.2019.06.006_bib18","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s13058-018-0950-x","article-title":"MRI-based response patterns during neoadjuvant chemotherapy can predict pathological (complete) response in patients with breast cancer","volume":"20","author":"Goorts","year":"2018","journal-title":"Breast Cancer Res"},{"key":"10.1016\/j.clbc.2019.06.006_bib19","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.tranon.2015.11.016","article-title":"Early prediction and evaluation of breast cancer response to neoadjuvant chemotherapy using quantitative DCE-MRI","volume":"9","author":"Tudorica","year":"2016","journal-title":"Transl Oncol"},{"key":"10.1016\/j.clbc.2019.06.006_bib20","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ejrad.2014.09.020","article-title":"Noninvasive nodal restaging in clinically node positive breast cancer patients after neoadjuvant systemic therapy: a systematic review","volume":"84","author":"Schipper","year":"2015","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.clbc.2019.06.006_bib21","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1023\/A:1014856713942","article-title":"Imaging in evaluation of response to neoadjuvant breast cancer treatment benefits of MRI","volume":"72","author":"Balu-Maestro","year":"2002","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.clbc.2019.06.006_bib22","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.clbc.2016.12.010","article-title":"Role of magnetic resonance imaging in detection of pathologic complete remission in breast cancer patients treated with neoadjuvant chemotherapy: a meta-analysis","volume":"17","author":"Gu","year":"2017","journal-title":"Clin Breast Cancer"},{"key":"10.1016\/j.clbc.2019.06.006_bib23","doi-asserted-by":"crossref","first-page":"8479","DOI":"10.1038\/s41598-017-08852-8","article-title":"Direct comparison of PET\/CT and MRI to predict the pathological response to neoadjuvant chemotherapy in breast cancer: a meta-analysis","volume":"7","author":"Chen","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.clbc.2019.06.006_bib24","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.jamcollsurg.2017.08.027","article-title":"MRI and prediction of pathologic complete response in the breast and axilla after neoadjuvant chemotherapy for breast cancer","volume":"225","author":"Weber","year":"2017","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.clbc.2019.06.006_bib25","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1245\/s10434-013-3118-z","article-title":"Imaging response and residual metastatic axillary lymph node disease after neoadjuvant chemotherapy for primary breast cancer","volume":"20","author":"Hieken","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clbc.2019.06.006_bib26","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1007\/s003300000370","article-title":"Axillary lymph node metastases in breast cancer: preoperative detection with dynamic contrast-enhanced MRI","volume":"10","author":"Kvistad","year":"2000","journal-title":"Eur Radiol"},{"key":"10.1016\/j.clbc.2019.06.006_bib27","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/jmri.21802","article-title":"Magnetic resonance imaging for axillary staging in patients with breast cancer","volume":"30","author":"Mortellaro","year":"2009","journal-title":"J\u00a0Magn Reson Imaging"}],"container-title":["Clinical Breast Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820919300370?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820919300370?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:18:45Z","timestamp":1761513525000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526820919300370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S1526820919300370"],"URL":"https:\/\/doi.org\/10.1016\/j.clbc.2019.06.006","relation":{},"ISSN":["1526-8209"],"issn-type":[{"value":"1526-8209","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MRI Volume Changes of Axillary Lymph Nodes as Predictor of Pathologic Complete Responses to Neoadjuvant Chemotherapy in Breast Cancer","name":"articletitle","label":"Article Title"},{"value":"Clinical Breast Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clbc.2019.06.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}