{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T09:08:13Z","timestamp":1790500093018,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007065","name":"Nvidia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinical-breast-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Breast Cancer"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.clbc.2020.06.001","type":"journal-article","created":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T11:04:53Z","timestamp":1591527893000},"page":"e757-e760","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Prospective Analysis Using a Novel CNN Algorithm to Distinguish Atypical Ductal Hyperplasia From Ductal Carcinoma in Situ in Breast"],"prefix":"10.1016","volume":"20","author":[{"given":"Simukayi","family":"Mutasa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4951-5932","authenticated-orcid":false,"given":"John","family":"Nemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo Pascual","family":"Van Sant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2847-3849","authenticated-orcid":false,"given":"Alison","family":"McIlvride","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6855-7321","authenticated-orcid":false,"given":"Maham","family":"Siddique","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clbc.2020.06.001_bib1","first-page":"7","article-title":"Cancer statistics, 2019","volume":"69","author":"Siegel","year":"2019","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.clbc.2020.06.001_bib2","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1159\/000350774","article-title":"A\u00a0Brief overview of the WHO Classification of Breast Tumors, 4th Edition, focusing on issues and updates from the 3rd edition","volume":"8","author":"Sinn","year":"2013","journal-title":"Breast Care (Basel)"},{"key":"10.1016\/j.clbc.2020.06.001_bib3","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1245\/s10434-016-5512-9","article-title":"Long-term safety of observation in selected women following core biopsy diagnosis of atypical ductal hyperplasia","volume":"24","author":"Menen","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clbc.2020.06.001_bib4","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ejca.2011.08.011","article-title":"Scoring to predict the possibility of upgrades to malignancy in atypical ductal hyperplasia diagnosed by an 11-gauge vacuum-assisted biopsy device: an external validation study","volume":"48","author":"Bendifallah","year":"2012","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.clbc.2020.06.001_bib5","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/his.13881","article-title":"Diagnostic upgrade of atypical ductal hyperplasia of the breast based on evaluation of histopathological features and calcification on core needle biopsy","volume":"75","author":"Chen","year":"2019","journal-title":"Histopathology"},{"key":"10.1016\/j.clbc.2020.06.001_bib6","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.breast.2010.06.004","article-title":"Factors associated with upgrading to malignancy at surgery of atypical ductal hyperplasia diagnosed on core biopsy","volume":"20","author":"Deshaies","year":"2011","journal-title":"Breast"},{"key":"10.1016\/j.clbc.2020.06.001_bib7","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s10549-007-9824-0","article-title":"Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy","volume":"112","author":"Ko","year":"2008","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.clbc.2020.06.001_bib8","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1245\/s10434-010-1127-8","article-title":"Atypical ductal hyperplasia in directional vacuum-assisted biopsy of breast microcalcifications: considerations for surgical excision","volume":"18","author":"Nguyen","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clbc.2020.06.001_bib9","doi-asserted-by":"crossref","first-page":"5374","DOI":"10.1200\/JCO.2007.14.8833","article-title":"Assessment of the accuracy of the Gail model in women with atypical hyperplasia","volume":"26","author":"Pankratz","year":"2008","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clbc.2020.06.001_bib10","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.2214\/AJR.18.20250","article-title":"Accuracy of distinguishing atypical ductal hyperplasia from ductal carcinoma in situ with convolutional neural network-based machine learning approach using mammographic image data","volume":"5","author":"Ha","year":"2019","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.clbc.2020.06.001_bib11","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3348\/kjr.2019.0025","article-title":"Design characteristics of studies reporting the performance of artificial intelligence algorithms for diagnostic analysis of medical images: results from recently published papers","volume":"20","author":"Kim","year":"2019","journal-title":"Korean J Radiol"},{"key":"10.1016\/j.clbc.2020.06.001_bib12","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1148\/radiol.2017171920","article-title":"Methodologic guide for evaluating clinical performance and effect of artificial intelligence technology for medical diagnosis and prediction","volume":"286","author":"Park","year":"2018","journal-title":"Radiology"},{"key":"10.1016\/j.clbc.2020.06.001_bib13","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1148\/radiol.2018182294","article-title":"Diagnostic case-control versus diagnostic cohort studies for clinical validation of artificial intelligence algorithm performance","volume":"290","author":"Park","year":"2019","journal-title":"Radiology"},{"key":"10.1016\/j.clbc.2020.06.001_bib14","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.carj.2018.03.003","article-title":"Use of breast magnetic resonance imaging in women diagnosed with atypical ductal hyperplasia at core needle biopsy helps select women for surgical excision","volume":"69","author":"Amitai","year":"2018","journal-title":"Can Assoc Radiol J"},{"key":"10.1016\/j.clbc.2020.06.001_bib15","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1002\/jmri.25694","article-title":"Value of breast MRI for patients with a biopsy showing atypical ductal hyperplasia (ADH)","volume":"46","author":"Tsuchiya","year":"2017","journal-title":"J\u00a0Magn Reson Imaging"},{"key":"10.1016\/j.clbc.2020.06.001_bib16","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/1746-1596-9-121","article-title":"Inter-observer variability between general pathologists and a specialist in breast pathology in the diagnosis of lobular neoplasia, columnar cell lesions, atypical ductal hyperplasia and ductal carcinoma in situ of the breast","volume":"9","author":"Gomes","year":"2014","journal-title":"Diagn Pathol"},{"key":"10.1016\/j.clbc.2020.06.001_bib17","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1158\/1055-9965.EPI-09-0745","article-title":"Rates of atypical ductal hyperplasia have declined with less use of postmenopausal hormone treatment: findings from the Breast Cancer Surveillance Consortium","volume":"18","author":"Menes","year":"2009","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.clbc.2020.06.001_bib18","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1148\/radiol.2018181352","article-title":"Radiomic versus convolutional neural networks analysis for classification of contrast-enhancing lesions at multiparametric breast MRI","volume":"290","author":"Truhn","year":"2019","journal-title":"Radiology"}],"container-title":["Clinical Breast Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820920301452?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820920301452?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:21:03Z","timestamp":1761513663000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526820920301452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S1526820920301452"],"URL":"https:\/\/doi.org\/10.1016\/j.clbc.2020.06.001","relation":{},"ISSN":["1526-8209"],"issn-type":[{"value":"1526-8209","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prospective Analysis Using a Novel CNN Algorithm to Distinguish Atypical Ductal Hyperplasia From Ductal Carcinoma in Situ in Breast","name":"articletitle","label":"Article Title"},{"value":"Clinical Breast Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clbc.2020.06.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}