{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T04:43:45Z","timestamp":1783226625887,"version":"3.54.6"},"reference-count":43,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA008748"],"award-info":[{"award-number":["P30CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinical-breast-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Breast Cancer"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.clbc.2025.10.001","type":"journal-article","created":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T02:39:32Z","timestamp":1759631972000},"page":"147-153","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Accelerated Partial Breast Irradiation (APBI) For Ductal Carcinoma In Situ"],"prefix":"10.1016","volume":"26","author":[{"given":"Diana Roth","family":"O\u2019Brien","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian","family":"Boe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Barrio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Isabelle","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Cuaron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beryl","family":"McCormick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atif J.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon N.","family":"Powell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5127-0217","authenticated-orcid":false,"given":"Lior Z.","family":"Braunstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.clbc.2025.10.001_bib0001","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1080\/02841860600681569","article-title":"SweDCIS: radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening","volume":"45","author":"Emdin","year":"2006","journal-title":"Acta Oncol"},{"issue":"4","key":"10.1016\/j.clbc.2025.10.001_bib0002","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/S0093-7754(01)90133-2","article-title":"Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience","volume":"28","author":"Fisher","year":"2001","journal-title":"Semin Oncol"},{"issue":"6","key":"10.1016\/j.clbc.2025.10.001_bib0003","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1093\/jnci\/djr027","article-title":"Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS","volume":"103","author":"Wapnir","year":"2011","journal-title":"J Natl Cancer Inst"},{"issue":"21","key":"10.1016\/j.clbc.2025.10.001_bib0004","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1200\/JCO.2006.06.1366","volume":"24","author":"Bijker","year":"2006","journal-title":"J Clin Oncol"},{"issue":"1","key":"10.1016\/j.clbc.2025.10.001_bib0005","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1470-2045(10)70266-7","article-title":"Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK\/ANZ DCIS trial","volume":"12","author":"Cuzick","year":"2011","journal-title":"Lancet Oncol"},{"issue":"32","key":"10.1016\/j.clbc.2025.10.001_bib0006","doi-asserted-by":"crossref","first-page":"5319","DOI":"10.1200\/JCO.2009.21.8560","article-title":"Local excision alone without irradiation for ductal carcinoma in situ of the breast: a trial of the Eastern Cooperative Oncology Group","volume":"27","author":"Hughes","year":"2009","journal-title":"J Clin Oncol"},{"issue":"7","key":"10.1016\/j.clbc.2025.10.001_bib0007","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1200\/JCO.2014.57.9029","article-title":"RTOG 9804: a prospective randomized trial for good-risk ductal carcinoma in situ comparing radiotherapy with observation","volume":"33","author":"McCormick","year":"2015","journal-title":"J Clin Oncol"},{"issue":"33","key":"10.1016\/j.clbc.2025.10.001_bib0008","doi-asserted-by":"crossref","first-page":"3938","DOI":"10.1200\/JCO.2015.60.8588","article-title":"Surgical excision without radiation for ductal carcinoma in situ of the breast: 12-year results from the ECOG-ACRIN E5194 study","volume":"33","author":"Solin","year":"2015","journal-title":"J Clin Oncol"},{"issue":"32","key":"10.1016\/j.clbc.2025.10.001_bib0009","doi-asserted-by":"crossref","first-page":"3574","DOI":"10.1200\/JCO.21.01083","article-title":"Randomized phase III trial evaluating radiation following surgical excision for good-risk ductal carcinoma In situ: long-term report from NRG Oncology\/RTOG 9804","volume":"39","author":"McCormick","year":"2021","journal-title":"J Clin Oncol"},{"issue":"5","key":"10.1016\/j.clbc.2025.10.001_bib0010","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1002\/1097-0142(19850901)56:5<979::AID-CNCR2820560502>3.0.CO;2-N","article-title":"Histologic multifocality of Tis, T1-2 breast carcinomas. Implications for clinical trials of breast-conserving surgery","volume":"56","author":"Holland","year":"1985","journal-title":"Cancer"},{"issue":"35","key":"10.1016\/j.clbc.2025.10.001_bib0011","doi-asserted-by":"crossref","first-page":"5591","DOI":"10.1200\/JCO.2007.11.4686","article-title":"Significance of multifocality in ductal carcinoma in situ: outcomes of women treated with breast-conserving therapy","volume":"25","author":"Rakovitch","year":"2007","journal-title":"J Clin Oncol"},{"issue":"10215","key":"10.1016\/j.clbc.2025.10.001_bib0012","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1016\/S0140-6736(19)32515-2","article-title":"External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial","volume":"394","author":"Whelan","year":"2019","journal-title":"Lancet"},{"issue":"10215","key":"10.1016\/j.clbc.2025.10.001_bib0013","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1016\/S0140-6736(19)32514-0","article-title":"Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial","volume":"394","author":"Vicini","year":"2019","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.clbc.2025.10.001_bib0014","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.ijrobp.2009.02.031","article-title":"Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO)","volume":"74","author":"Smith","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.clbc.2025.10.001_bib0015","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S1470-2045(17)30011-6","volume":"18","author":"Polgar","year":"2017","journal-title":"Lancet Oncol"},{"issue":"10015","key":"10.1016\/j.clbc.2025.10.001_bib0016","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0140-6736(15)00471-7","volume":"387","author":"Strnad","year":"2016","journal-title":"Lancet"},{"issue":"10099","key":"10.1016\/j.clbc.2025.10.001_bib0017","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/S0140-6736(17)31145-5","article-title":"Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial","volume":"390","author":"Coles","year":"2017","journal-title":"Lancet"},{"issue":"35","key":"10.1016\/j.clbc.2025.10.001_bib0018","doi-asserted-by":"crossref","first-page":"4175","DOI":"10.1200\/JCO.20.00650","article-title":"Accelerated partial-breast irradiation compared with whole-breast irradiation for early breast cancer: long-term results of the randomized phase III APBI-IMRT-Florence trial","volume":"38","author":"Meattini","year":"2020","journal-title":"J Clin Oncol"},{"issue":"2","key":"10.1016\/j.clbc.2025.10.001_bib0019","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.ijrobp.2009.04.070","article-title":"Accelerated partial breast irradiation with IMRT: new technical approach and interim analysis of acute toxicity in a phase III randomized clinical trial","volume":"77","author":"Livi","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.clbc.2025.10.001_bib0020","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.prro.2016.09.007","article-title":"Accelerated partial breast irradiation: executive summary for the update of an ASTRO evidence-based consensus statement","volume":"7","author":"Correa","year":"2017","journal-title":"Pract Radiat Oncol"},{"issue":"4","key":"10.1016\/j.clbc.2025.10.001_bib0021","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.ijrobp.2019.02.050","article-title":"Daily fractionation of external beam accelerated partial breast irradiation to 40 gy is well tolerated and locally effective","volume":"104","author":"Braunstein","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"10.1016\/j.clbc.2025.10.001_bib0022","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.brachy.2017.09.004","article-title":"The American Brachytherapy Society consensus statement for accelerated partial-breast irradiation","volume":"17","author":"Shah","year":"2018","journal-title":"Brachytherapy"},{"issue":"3","key":"10.1016\/j.clbc.2025.10.001_bib0023","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.radonc.2010.01.014","volume":"94","author":"Polgar","year":"2010","journal-title":"Radiother Oncol"},{"issue":"35","key":"10.1016\/j.clbc.2025.10.001_bib0024","doi-asserted-by":"crossref","first-page":"4175","DOI":"10.1200\/JCO.20.00650","article-title":"Accelerated partial-breast irradiation compared with whole-breast irradiation for early breast cancer: long-term results of the randomized phase III APBI-IMRT-Florence trial","volume":"38","author":"Meattini","year":"2020","journal-title":"J Clin Oncol"},{"issue":"3","key":"10.1016\/j.clbc.2025.10.001_bib0025","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1177\/0300891618811278","article-title":"External accelerated partial breast irradiation for ductal carcinoma in situ: long-term follow-up from a phase 3 randomized trial","volume":"105","author":"Becherini","year":"2019","journal-title":"Tumori"},{"issue":"11","key":"10.1016\/j.clbc.2025.10.001_bib0026","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.1245\/s10434-010-1044-x","article-title":"Ductal carcinoma in situ of the breast treated with accelerated partial breast irradiation using balloon-based brachytherapy","volume":"17","author":"Israel","year":"2010","journal-title":"Ann Surg Oncol"},{"issue":"4_Supplement","key":"10.1016\/j.clbc.2025.10.001_bib0027","doi-asserted-by":"crossref","first-page":"P6-16-05","DOI":"10.1158\/1538-7445.SABCS19-P6-16-05","article-title":"Abstract P6-16-05: clinical outcomes achieved with brachytherapy vs whole breast irradiation for ductal carcinoma in situ","volume":"80","author":"Nguyen","year":"2020","journal-title":"Cancer Research"},{"issue":"1","key":"10.1016\/j.clbc.2025.10.001_bib0028","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ijrobp.2010.08.034","article-title":"Outcomes in women treated with MammoSite brachytherapy or whole breast irradiation stratified by ASTRO Accelerated Partial Breast Irradiation Consensus Statement groups","volume":"82","author":"Zauls","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"10.1016\/j.clbc.2025.10.001_bib0029","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.amjsurg.2009.06.013","article-title":"American Society of Breast Surgeons MammoSite Radiation Therapy System Registry Trial: ductal carcinoma-in-situ subset analysis\u20134-year data in 194 treated lesions","volume":"198","author":"Keisch","year":"2009","journal-title":"Am J Surg"},{"issue":"1","key":"10.1016\/j.clbc.2025.10.001_bib0030","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1245\/s10434-010-1192-z","article-title":"Update on DCIS outcomes from the American Society of Breast Surgeons accelerated partial breast irradiation registry trial","volume":"18","author":"Jeruss","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clbc.2025.10.001_bib0031","doi-asserted-by":"crossref","first-page":"3165","DOI":"10.1245\/s10434-012-2489-x","article-title":"Tumor bed control with balloon-based accelerated partial breast irradiation: incidence of true recurrences versus elsewhere failures in the American Society of Breast Surgery MammoSite\u00ae Registry Trial","volume":"19","author":"Beitsch","year":"2012","journal-title":"Ann Surg Oncol"},{"issue":"6","key":"10.1016\/j.clbc.2025.10.001_bib0032","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1002\/cncr.25615","article-title":"Ductal carcinoma in situ treated with breast-conserving surgery and accelerated partial breast irradiation: comparison of the Mammosite registry trial with intergroup study E5194","volume":"117","author":"Goyal","year":"2011","journal-title":"Cancer"},{"key":"10.1016\/j.clbc.2025.10.001_bib0033","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1245\/s10434-011-1941-7","article-title":"A single-institution review of accelerated partial breast irradiation in patients considered \u201ccautionary\u201d by the American Society for Radiation Oncology","volume":"19","author":"Stull","year":"2012","journal-title":"Ann Surg Oncol"},{"issue":"4","key":"10.1016\/j.clbc.2025.10.001_bib0034","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1245\/s10434-012-2694-7","article-title":"Should ductal carcinoma-in-situ (DCIS) be removed from the ASTRO consensus panel cautionary group for off-protocol use of accelerated partial breast irradiation (APBI)? A pooled analysis of outcomes for 300 patients with DCIS treated with APBI","volume":"20","author":"Vicini","year":"2013","journal-title":"Ann Surg Oncol"},{"issue":"1","key":"10.1016\/j.clbc.2025.10.001_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijrobp.2019.06.646","article-title":"Accelerated partial-breast irradiation (APBI) for ductal carcinoma in situ (DCIS): outcomes from a single-institution prospective registry","volume":"105","author":"Brenneman","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.clbc.2025.10.001_bib0036","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.brachy.2020.11.002","article-title":"Management of ductal carcinoma in situ with accelerated partial breast irradiation brachytherapy: implications for guideline expansion","volume":"20","author":"Mills","year":"2021","journal-title":"Brachytherapy"},{"issue":"5","key":"10.1016\/j.clbc.2025.10.001_bib0037","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.amjsurg.2023.03.004","article-title":"DCIS: when is accelerated partial breast irradiation an option? A meta-analysis on outcomes and eligibility","volume":"225","author":"Chua","year":"2023","journal-title":"Am J Surg"},{"issue":"10215","key":"10.1016\/j.clbc.2025.10.001_bib0038","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1016\/S0140-6736(19)32514-0","article-title":"Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial","volume":"394","author":"Vicini","year":"2019","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.clbc.2025.10.001_bib0039","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.brachy.2019.02.008","article-title":"Compendium of fractionation choices for gynecologic HDR brachytherapy-an American Brachytherapy Society Task Group Report","volume":"18","author":"Albuquerque","year":"2019","journal-title":"Brachytherapy"},{"issue":"2","key":"10.1016\/j.clbc.2025.10.001_bib0040","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.prro.2023.11.001","article-title":"Partial breast irradiation for patients with early-stage invasive breast cancer or ductal carcinoma In situ: an ASTRO clinical practice guideline","volume":"14","author":"Shaitelman","year":"2024","journal-title":"Pract Radiat Oncol"},{"issue":"1","key":"10.1016\/j.clbc.2025.10.001_bib0041","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41523-024-00622-w","article-title":"Lumpectomy without radiation for ductal carcinoma in situ of the breast: 20-year results from the ECOG-ACRIN E5194 study","volume":"10","author":"Wright","year":"2024","journal-title":"NPJ Breast Cancer"},{"issue":"7","key":"10.1016\/j.clbc.2025.10.001_bib0042","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1158\/1940-6207.CAPR-17-0029","article-title":"Tamoxifen acceptance and adherence among patients with ductal carcinoma In situ (DCIS) treated in a multidisciplinary setting","volume":"10","author":"Karavites","year":"2017","journal-title":"Cancer Prev Res (Phila)"},{"issue":"9169","key":"10.1016\/j.clbc.2025.10.001_bib0043","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1016\/S0140-6736(99)05036-9","article-title":"Tamoxifen in treatment of intraductal breast cancer: national Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial","volume":"353","author":"Fisher","year":"1999","journal-title":"Lancet"}],"container-title":["Clinical Breast Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820925002915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820925002915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T13:08:43Z","timestamp":1773407323000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526820925002915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S1526820925002915"],"URL":"https:\/\/doi.org\/10.1016\/j.clbc.2025.10.001","relation":{},"ISSN":["1526-8209"],"issn-type":[{"value":"1526-8209","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Accelerated Partial Breast Irradiation (APBI) For Ductal Carcinoma In Situ","name":"articletitle","label":"Article Title"},{"value":"Clinical Breast Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clbc.2025.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}