{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T15:43:03Z","timestamp":1773416583062,"version":"3.50.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinical-breast-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Breast Cancer"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.clbc.2026.01.012","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T16:53:00Z","timestamp":1769705580000},"page":"94-101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hard and Soft MRI Signs of Nipple-Areolar Complex Involvement in Breast Cancer"],"prefix":"10.1016","volume":"26","author":[{"given":"Tal","family":"Friehmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Shpitzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marva Dahan","family":"Shemesh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eli","family":"Atar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noa","family":"Rotbart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzippy","family":"Shochat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meirav","family":"Wolff-Bar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shlomit","family":"Tamir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladyslav","family":"Gaisinskyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eran","family":"Sharon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahuva","family":"Grubstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clbc.2026.01.012_bib0001","doi-asserted-by":"crossref","first-page":"739","DOI":"10.3348\/kjr.2022.0846","article-title":"Diagnostic accuracy of magnetic resonance imaging features and tumor-to-nipple distance for the nipple-areolar complex involvement of breast cancer: a systematic review and meta-analysis","volume":"24","author":"Byon","year":"2023","journal-title":"Korean J Radiol"},{"key":"10.1016\/j.clbc.2026.01.012_bib0002","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1148\/radiol.2021204136","article-title":"Diagnostic accuracy of nonmass enhancement at breast MRI in predicting tumor involvement of the nipple: a prospective study in a single institution","volume":"301","author":"Bae","year":"2021","journal-title":"Radiology"},{"key":"10.1016\/j.clbc.2026.01.012_bib0003","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1148\/rg.2019180039","article-title":"An analysis of nipple enhancement at breast MRI with radiologic-pathologic correlation","volume":"39","author":"Gao","year":"2019","journal-title":"Radiographics"},{"key":"10.1016\/j.clbc.2026.01.012_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinimag.2024.110305","article-title":"Diffuse unilateral MRI breast entities","volume":"115","author":"Sivarajah","year":"2024","journal-title":"Clin Imaging"},{"key":"10.1016\/j.clbc.2026.01.012_bib0005","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1001\/jamasurg.2022.2065","article-title":"Analysis of a trend reversal in US lumpectomy rates from 2005 through 2017 using 3 nationwide data sets","volume":"157","author":"Nelson","year":"2022","journal-title":"JAMA Surg"},{"key":"10.1016\/j.clbc.2026.01.012_bib0006","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ejca.2016.03.081","article-title":"RECIST 1.1\u2014Update and clarification: from the RECIST committee","volume":"62","author":"Schwartz","year":"2016","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.clbc.2026.01.012_bib0007","doi-asserted-by":"crossref","first-page":"328","DOI":"10.5999\/aps.2016.43.4.328","article-title":"The oncological safety of nipple-sparing mastectomy: a systematic review of the literature with a pooled analysis of 12,358 procedures","volume":"43","author":"Headon","year":"2016","journal-title":"Arch Plast Surg"},{"key":"10.1016\/j.clbc.2026.01.012_bib0008","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1148\/rg.210136","article-title":"Nipple-sparing mastectomy: what the radiologist should know","volume":"42","author":"Lee","year":"2022","journal-title":"Radiographics"},{"key":"10.1016\/j.clbc.2026.01.012_bib0009","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ejca.2016.03.081","article-title":"RECIST 1.1\u2014Update and clarification: from the RECIST Committee","volume":"62","author":"Schwartz","year":"2016","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.clbc.2026.01.012_bib0010","doi-asserted-by":"crossref","first-page":"W1","DOI":"10.2214\/AJR.15.15187","article-title":"MRI to predict nipple involvement in breast cancer patients","volume":"206","author":"Piato","year":"2016","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.clbc.2026.01.012_bib0011","doi-asserted-by":"crossref","first-page":"3683","DOI":"10.1007\/s00330-020-07550-w","article-title":"MIP image derived from abbreviated breast MRI: potential to reduce unnecessary sub-nipple biopsies during nipple-sparing mastectomy for breast cancer","volume":"31","author":"Liu","year":"2021","journal-title":"Eur Radiol"},{"key":"10.1016\/j.clbc.2026.01.012_bib0012","doi-asserted-by":"crossref","DOI":"10.1148\/rg.230113","article-title":"Multimodality imaging of benign and malignant diseases of the nipple-areolar complex","volume":"44","author":"Guirguis","year":"2024","journal-title":"Radiographics"},{"key":"10.1016\/j.clbc.2026.01.012_bib0013","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.crad.2020.09.013","article-title":"The nipple-areolar complex: comprehensive imaging review","volume":"76","author":"Lyons","year":"2021","journal-title":"Clin Radiol"},{"key":"10.1016\/j.clbc.2026.01.012_bib0014","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1148\/rg.292085128","article-title":"Nipple-areolar complex: normal anatomy and benign and malignant processes","volume":"29","author":"Nicholson","year":"2009","journal-title":"Radiographics"},{"issue":"Suppl 1","key":"10.1016\/j.clbc.2026.01.012_bib0015","first-page":"S65","article-title":"Common and unusual diseases of the nipple-areolar complex","volume":"27","author":"D","year":"2007","journal-title":"Radiographics"},{"key":"10.1016\/j.clbc.2026.01.012_bib0016","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20201013","article-title":"Magnetic resonance imaging in the evaluation of pathologic nipple discharge: indications and imaging findings","volume":"94","author":"Samreen","year":"2021","journal-title":"Br J Radiol"},{"key":"10.1016\/j.clbc.2026.01.012_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejso.2024.108320","article-title":"Intraoperative frozen section of subareolar tissue in nipple-sparing mastectomy: towards a less-is-more approach","volume":"50","author":"Spoor","year":"2024","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.clbc.2026.01.012_bib0018","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1093\/ajcp\/aqab126","article-title":"Subareolar tissue biopsy predicts occult nipple involvement in nipple-sparing mastectomies","volume":"157","author":"Ma","year":"2022","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.clbc.2026.01.012_bib0019","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/tbj.14197","article-title":"Intraoperative central nipple biopsy in nipple-sparing mastectomy: a retrospective analysis of 211 patients","volume":"27","author":"Eichler","year":"2021","journal-title":"Breast J"},{"key":"10.1016\/j.clbc.2026.01.012_bib0020","first-page":"188","article-title":"The accuracy of intraoperative subareolar frozen section in nipple-sparing mastectomies","volume":"10","author":"Luo","year":"2010","journal-title":"Ochsner J"},{"key":"10.1016\/j.clbc.2026.01.012_bib0021","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.anndiagpath.2017.05.001","article-title":"Accuracy and interobserver agreement of retroareolar frozen sections in nipple-sparing mastectomies","volume":"29","author":"Suarez-Zamora","year":"2017","journal-title":"Ann Diagn Pathol"}],"container-title":["Clinical Breast Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820926000121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526820926000121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T12:36:15Z","timestamp":1773405375000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526820926000121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S1526820926000121"],"URL":"https:\/\/doi.org\/10.1016\/j.clbc.2026.01.012","relation":{},"ISSN":["1526-8209"],"issn-type":[{"value":"1526-8209","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hard and Soft MRI Signs of Nipple-Areolar Complex Involvement in Breast Cancer","name":"articletitle","label":"Article Title"},{"value":"Clinical Breast Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clbc.2026.01.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}