{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T23:11:04Z","timestamp":1761520264560,"version":"build-2065373602"},"reference-count":38,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinical-colorectal-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Colorectal Cancer"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.clcc.2018.04.001","type":"journal-article","created":{"date-parts":[[2018,4,21]],"date-time":"2018-04-21T13:35:11Z","timestamp":1524317711000},"page":"e519-e530","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Adjuvant Management of Pathologic Node\u2013Positive Disease After Definitive Surgery for Clinical T1-2 N0 Rectal Cancer"],"prefix":"10.1016","volume":"17","author":[{"given":"Praveen","family":"Polamraju","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waqar","family":"Haque","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Verma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee","family":"Wiederhold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Hatch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. Brian","family":"Butler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin S.","family":"Teh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clcc.2018.04.001_bib1","unstructured":"National Comprehensive Cancer Network. NCCN clinical practice guidelines: esophageal and esophagogastric junction cancers, version 1.2017. Available at: https:\/\/www.nccn.org\/professionals\/physician_gls\/default.aspx. Accessed February 1, 2018."},{"key":"10.1016\/j.clcc.2018.04.001_bib2","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1097\/01.sla.0000252590.95116.4f","article-title":"Is the increasing rate of local excision for stage I rectal cancer in the United States justified? A nationwide cohort study from the National Cancer Database","volume":"245","author":"You","year":"2007","journal-title":"Ann Surg"},{"key":"10.1016\/j.clcc.2018.04.001_bib3","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s10350-004-6147-7","article-title":"Risk of lymph node metastasis in T1 carcinoma of the colon and rectum","volume":"45","author":"Nascimbeni","year":"2002","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.clcc.2018.04.001_bib4","first-page":"438450","article-title":"Analysis of risk factors for lymph nodal involvement in early stages of rectal cancer: when can local excision be considered an appropriate treatment? Systematic review and meta-analysis of the literature","volume":"2012","author":"Carrara","year":"2012","journal-title":"Int J Surg Oncol"},{"key":"10.1016\/j.clcc.2018.04.001_bib5","first-page":"1688","article-title":"Metastatic potential in T1 and T2 colorectal cancer","volume":"52","author":"Fang","year":"2005","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.clcc.2018.04.001_bib6","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/DCR.0b013e3181a0adbd","article-title":"Long-term survival after transanal excision of T1 rectal cancer","volume":"52","author":"Nash","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.clcc.2018.04.001_bib7","doi-asserted-by":"crossref","first-page":"W42","DOI":"10.2214\/AJR.14.14201","article-title":"MRI of rectal cancer: an overview and update on recent advances","volume":"205","author":"Jhaveri","year":"2015","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.clcc.2018.04.001_bib8","doi-asserted-by":"crossref","first-page":"390","DOI":"10.5152\/dir.2014.13265","article-title":"MRI in local staging of rectal cancer: an update","volume":"20","author":"Tapan","year":"2014","journal-title":"Diagn Interv Radiol"},{"key":"10.1016\/j.clcc.2018.04.001_bib9","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1148\/radiol.2323031368","article-title":"Rectal cancer: local staging and assessment of lymph node involvement with endoluminal US, CT, and MR imaging\u2014a meta analysis","volume":"232","author":"Bipat","year":"2004","journal-title":"Radiology"},{"key":"10.1016\/j.clcc.2018.04.001_bib10","doi-asserted-by":"crossref","first-page":"e92779","DOI":"10.1371\/journal.pone.0092779","article-title":"Prediction of nodal involvement in primary rectal carcinoma without invasion to pelvic structures: accuracy of preoperative CT, MR, and DWIBS assessments relative to histopathologic findings","volume":"9","author":"Zhou","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.clcc.2018.04.001_bib11","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/RCT.0b013e318225720f","article-title":"Nodal Staging of rectal cancer: high resolution MRI vs 18F-FDGPET\/CT","volume":"35","author":"Kim","year":"2011","journal-title":"J\u00a0Comput Assist Tomogr"},{"key":"10.1016\/j.clcc.2018.04.001_bib12","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s11605-016-3301-1","article-title":"Clinically node negative, pathologically node positive rectal cancer patients who did not receive neoadjuvant therapy","volume":"21","author":"Akeel","year":"2017","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1016\/j.clcc.2018.04.001_bib13","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1245\/s10434-007-9747-3","article-title":"The National Cancer Data Base: a powerful initiative to improve cancer care in the United States","volume":"15","author":"Bilimoria","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clcc.2018.04.001_bib14","first-page":"1","article-title":"Management of pathologic node-positive disease following initial surgery for clinical T1-T2 N0 esophageal cancer: patterns of care and outcomes from the national cancer data base.","author":"Haque","year":"2017","journal-title":"Acta Oncol"},{"key":"10.1016\/j.clcc.2018.04.001_bib15","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s11060-017-2443-7","article-title":"Patterns of care and outcomes of multi-agent versus single-agent chemotherapy as part of multimodal management of low grade glioma","volume":"133","author":"Haque","year":"2017","journal-title":"J\u00a0Neurooncol"},{"key":"10.1016\/j.clcc.2018.04.001_bib16","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.lungcan.2016.11.009","article-title":"Trends in stereotactic body radiation therapy for stage I small cell lung cancer","volume":"103","author":"Stahl","year":"2017","journal-title":"Lung Cancer"},{"key":"10.1016\/j.clcc.2018.04.001_bib17","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.ijrobp.2017.04.004","article-title":"Radiation treatment time and overall survival in locally advanced non\u2013small cell lung cancer","volume":"98","author":"McMillan","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clcc.2018.04.001_bib18","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1056\/NEJMoa040694","article-title":"Preoperative versus postoperative chemoradiotherapy for rectal cancer","volume":"351","author":"Sauer","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.clcc.2018.04.001_bib19","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1287\/opre.36.1.93","article-title":"Relaxation methods for minimum cost ordinary and generalized network flow problems","volume":"36","author":"Bertsekas","year":"1988","journal-title":"Oper Res"},{"key":"10.1016\/j.clcc.2018.04.001_bib20","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1198\/016214504000000647","article-title":"Full matching in an observational study of coaching for the SAT","volume":"99","author":"Hansen","year":"2004","journal-title":"J\u00a0Am Stat Assoc"},{"key":"10.1016\/j.clcc.2018.04.001_bib21","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1198\/106186006X137047","article-title":"Optimal full matching and related designs via network flows","volume":"15","author":"Hansen","year":"2006","journal-title":"J\u00a0Comput Graph Stat"},{"key":"10.1016\/j.clcc.2018.04.001_bib22","first-page":"219","article-title":"Covariate balance in simple, stratified and clustered comparative studies","volume":"2","author":"Hansen","year":"2008","journal-title":"Stat Sci"},{"key":"10.1016\/j.clcc.2018.04.001_bib23","article-title":"Matchit: nonparametric preprocessing for parametric causal inference","volume":"42","author":"Ho","year":"2011","journal-title":"J\u00a0Stat Softw"},{"key":"10.1016\/j.clcc.2018.04.001_bib24","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/pan\/mpl013","article-title":"Matching as nonparametric preprocessing for reducing model dependence in parametric causal inference","volume":"15","author":"Ho","year":"2007","journal-title":"Polit Anal"},{"key":"10.1016\/j.clcc.2018.04.001_bib25","first-page":"1","article-title":"CEM: software for coarsened exact matching","volume":"30","author":"Iacus","year":"2009","journal-title":"J\u00a0Stat Softw"},{"key":"10.1016\/j.clcc.2018.04.001_bib26","unstructured":"Thoemmes F. Propensity score matching in SPSS 2012. Available at: http:\/\/arxiv.org\/abs\/1201.6385. Accessed February 1, 2018."},{"key":"10.1016\/j.clcc.2018.04.001_bib27","unstructured":"Bates D. Maechler M. Bolker B. et al., lme4: Linear mixed effects models using Eigen and S4. R package version 1.0-4 2013. Available at: http:\/\/CRAN.R-project.org\/package=lme4. Accessed February 1, 2018."},{"key":"10.1016\/j.clcc.2018.04.001_bib28","unstructured":"Thoemmes F, Liao W. Propensity score matching (with multi level data) using SPSS and R. Paper presented at: Modern Modeling Methods Conference; Storrs, CT;\u00a02013."},{"key":"10.1016\/j.clcc.2018.04.001_bib29","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.1002\/sim.3697","article-title":"Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples","volume":"28","author":"Austin","year":"2009","journal-title":"Stat Med"},{"key":"10.1016\/j.clcc.2018.04.001_bib30","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1177\/1758834014523328","article-title":"Treatment of older patients with colorectal cancer","volume":"6","author":"Kordatou","year":"2014","journal-title":"Ther Adv Med Oncol"},{"key":"10.1016\/j.clcc.2018.04.001_bib31","doi-asserted-by":"crossref","first-page":"4309","DOI":"10.1002\/cncr.27422","article-title":"Comparison of adverse events during 5-fluorouracil versus 5-fluorouracil\/oxaliplatin adjuvant chemotherapy for stage III colon cancer: a population-based analysis","volume":"118","author":"Sanoff","year":"2012","journal-title":"Cancer"},{"key":"10.1016\/j.clcc.2018.04.001_bib32","first-page":"25","article-title":"Stratification of rectal cancer stage for selection of postoperative chemoradiotherapy: current status","volume":"2","author":"Gunderson","year":"2008","journal-title":"Gastrointest Cancer Res"},{"key":"10.1016\/j.clcc.2018.04.001_bib33","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/00000478-200203000-00009","article-title":"Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit","volume":"26","author":"Nagtegaal","year":"2002","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.clcc.2018.04.001_bib34","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1097\/DCR.0000000000000870","article-title":"Postoperative chemotherapy after local resection for high-risk T1 to T2 low rectal cancer: results of a single-arm, multi-institutional, phase ii clinical trial","volume":"60","author":"Sasaki","year":"2017","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.clcc.2018.04.001_bib35","first-page":"998","article-title":"The risk of lymph node metastasis in T1 colorectal carcinoma","volume":"51","author":"Yamamoto","year":"2004","journal-title":"Hepatogastroentereology"},{"key":"10.1016\/j.clcc.2018.04.001_bib36","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1093\/jnci\/92.5.388","article-title":"Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02","volume":"1","author":"Wolmark","year":"2000","journal-title":"J\u00a0Natl Cancer Inst"},{"key":"10.1016\/j.clcc.2018.04.001_bib37","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0140-6736(94)92206-3","article-title":"Role of circumferential margin\u00a0involvement in the local recurrence of rectal cancer","volume":"344","author":"Adam","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.clcc.2018.04.001_bib38","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1007\/s11605-011-1497-7","article-title":"Effects of postoperative adjuvant radiotherapy on recurrence and survival in stage III rectal cancer","volume":"15","author":"Huh","year":"2011","journal-title":"J\u00a0Gastrointest Surg"}],"container-title":["Clinical Colorectal Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1533002818301208?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1533002818301208?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T23:06:13Z","timestamp":1761519973000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1533002818301208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S1533002818301208"],"URL":"https:\/\/doi.org\/10.1016\/j.clcc.2018.04.001","relation":{},"ISSN":["1533-0028"],"issn-type":[{"type":"print","value":"1533-0028"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adjuvant Management of Pathologic Node\u2013Positive Disease After Definitive Surgery for Clinical T1-2 N0 Rectal Cancer","name":"articletitle","label":"Article Title"},{"value":"Clinical Colorectal Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clcc.2018.04.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}