{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T18:52:22Z","timestamp":1763664742701,"version":"build-2065373602"},"reference-count":95,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinical-colorectal-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Colorectal Cancer"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.clcc.2021.11.008","type":"journal-article","created":{"date-parts":[[2021,11,28]],"date-time":"2021-11-28T17:22:29Z","timestamp":1638120149000},"page":"e126-e134","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Targeting Hyaluronic Acid and Peritoneal Dissemination in Colorectal Cancer"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9283-0006","authenticated-orcid":false,"given":"Faris","family":"Soliman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenguo","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Hargest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0001","first-page":"87","article-title":"Global cancer statistics","volume":"65","author":"Torre","year":"2012","journal-title":"CA Cancer J Clin"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0002","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/ans.13969","article-title":"Influence of primary site on metastatic distribution and survival in stage IV colorectal cancer","volume":"88","author":"Suthananthan","year":"2017","journal-title":"ANZ J Surg"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0003","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s10151-005-0205-6","article-title":"Peritoneal surface oncology: review of a personal experience with colorectal and appendiceal malignancy","volume":"9","author":"Sugarbaker","year":"2005","journal-title":"Tech Coloproctol"},{"issue":"4","key":"10.1016\/j.clcc.2021.11.008_bib0004","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/01.cco.0000161746.32511.41","article-title":"Colorectal carcinomatosis: a new oncologic frontier","volume":"17","author":"Sugarbaker","year":"2005","journal-title":"Curr Opin Oncol"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0005","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0344-0338(11)80700-4","article-title":"The pathologist and the residual tumor (R) classification","volume":"190","author":"Hermanek","year":"1994","journal-title":"Pathol Res Pract"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0006","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1159\/000444097","article-title":"Clinicopathological factors associated with recurrence and prognosis after R0 resection for stage IV colorectal cancer with peritoneal metastasis","volume":"33","author":"Sato","year":"2016","journal-title":"Dig Surg"},{"issue":"12","key":"10.1016\/j.clcc.2021.11.008_bib0007","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1046\/j.1365-2168.2002.02274.x","article-title":"Peritoneal carcinomatosis from colorectal cancer","volume":"89","author":"Jayne","year":"2002","journal-title":"Br J Surg"},{"year":"2012","series-title":"Langman's Medical Embryology","author":"Sadler","key":"10.1016\/j.clcc.2021.11.008_bib0008"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0009","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.tice.2016.11.004","article-title":"The histophysiology and pathophysiology of the peritoneum","volume":"49","author":"van Baal","year":"2017","journal-title":"Tissue Cell"},{"issue":"13","key":"10.1016\/j.clcc.2021.11.008_bib0010","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.addr.2007.08.008","article-title":"Hyaluronan-dependent pericellular matrix","volume":"59","author":"Evanko","year":"2007","journal-title":"Adv Drug Deliv Rev"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0011","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/aja.1002040209","article-title":"Ectodermal stimulation of the production of hyaluronan-dependent pericellular matrix by embryonic limb mesodermal cells","volume":"204","author":"Knudson","year":"1995","journal-title":"Dev Dyn"},{"issue":"7","key":"10.1016\/j.clcc.2021.11.008_bib0012","doi-asserted-by":"crossref","first-page":"4581","DOI":"10.1074\/jbc.R100037200","article-title":"Hyaluronan and homeostasis: a balancing act","volume":"277","author":"Tammi","year":"2002","journal-title":"J Biol Chem"},{"issue":"51","key":"10.1016\/j.clcc.2021.11.008_bib0013","doi-asserted-by":"crossref","first-page":"36777","DOI":"10.1074\/jbc.R700036200","article-title":"Hyaluronan synthases: a decade-plus of novel glycosyltransferases","volume":"282","author":"Weigel","year":"2007","journal-title":"J Biol Chem"},{"issue":"22","key":"10.1016\/j.clcc.2021.11.008_bib0014","doi-asserted-by":"crossref","first-page":"13997","DOI":"10.1074\/jbc.272.22.13997","article-title":"Hyaluronan synthases","volume":"272","author":"Weigel","year":"1997","journal-title":"J Biol Chem"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0015","doi-asserted-by":"crossref","first-page":"A1","DOI":"10.1038\/icb.1996.32","article-title":"The structure and function of hyaluronan: an overview","volume":"74","author":"Laurent","year":"1996","journal-title":"Immunol Cell Biol"},{"issue":"7","key":"10.1016\/j.clcc.2021.11.008_bib0016","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1096\/fasebj.6.7.1563592","article-title":"Hyaluronan","volume":"6","author":"Laurent","year":"1992","journal-title":"FASEB J"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0017","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0945-053X(01)00186-X","article-title":"CD44-mediated uptake and degradation of hyaluronan","volume":"21","author":"Knudson","year":"2002","journal-title":"Matrix Biol"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0018","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0169-409X(91)90004-V","article-title":"Turnover of Hyaluronan in the Tissues","volume":"7","author":"Laurent","year":"1991","journal-title":"Adv Drug Del Rev"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0019","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1046\/j.1440-1843.2002.00404.x","article-title":"Mesothelial cells: their structure, function and role in serosal repair","volume":"7","author":"Mutsaers","year":"2002","journal-title":"Respirology"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0020","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/BF00235068","article-title":"Mesothelial stomata overlying omental milky spots: scanning electron microscopic study","volume":"201","author":"Mironov","year":"1979","journal-title":"Cell Tissue Res"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0021","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.fertnstert.2016.09.005","article-title":"Mesothelial cells and peritoneal homeostasis","volume":"106","author":"Mutsaers","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.clcc.2021.11.008_bib0022","doi-asserted-by":"crossref","first-page":"113","DOI":"10.3389\/fphar.2015.00113","article-title":"Mesothelial cells in tissue repair and fibrosis","volume":"6","author":"Mutsaers","year":"2015","journal-title":"Front Pharmacol"},{"issue":"Pt 3","key":"10.1016\/j.clcc.2021.11.008_bib0023","first-page":"375","article-title":"Regeneration of parietal and visceral peritoneum: an electron microscopical study","volume":"115","author":"Raftery","year":"1973","journal-title":"J Anat"},{"key":"10.1016\/j.clcc.2021.11.008_bib0024","doi-asserted-by":"crossref","unstructured":"Nolph, K.D., Peritoneal Anatomy and Transport Physiology, in Replacement of Renal Function by Dialysis, P.F.M. Drukker W., Maher J.F., Editor. 1983, Springer, Dordrecht.","DOI":"10.1007\/978-94-009-6768-7_22"},{"issue":"Pt 7","key":"10.1016\/j.clcc.2021.11.008_bib0025","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1242\/jcs.115.7.1383","article-title":"Evidence for incorporation of free-floating mesothelial cells as a mechanism of serosal healing","volume":"115","author":"Foley-Comer","year":"2002","journal-title":"J Cell Sci"},{"issue":"6","key":"10.1016\/j.clcc.2021.11.008_bib0026","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1053\/j.sempedsurg.2014.06.002","article-title":"Anatomy and physiology of the peritoneum","volume":"23","author":"Blackburn","year":"2014","journal-title":"Semin Pediatr Surg"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0027","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s00276-008-0456-9","article-title":"Peritoneal surface area: measurements of 40 structures covered by peritoneum: correlation between total peritoneal surface area and the surface calculated by formulas","volume":"31","author":"Albanese","year":"2009","journal-title":"Surg Radiol Anat"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0028","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1097\/00000441-198805000-00007","article-title":"Measurements of peritoneal surface area in man and rat","volume":"295","author":"Rubin","year":"1988","journal-title":"Am J Med Sci"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0029","doi-asserted-by":"crossref","first-page":"198","DOI":"10.2214\/ajr.119.1.198","article-title":"Distribution of intra-abdominal malignant seeding: dependency on dynamics of flow of ascitic fluid","volume":"119","author":"Meyers","year":"1973","journal-title":"Am J Roentgenol Radium Ther Nucl Med"},{"key":"10.1016\/j.clcc.2021.11.008_bib0030","series-title":"Peritoneal Surface Malignancies","article-title":"Molecular Mechanism of Peritoneal Metastases","author":"Canbay E","year":"2015"},{"issue":"007","key":"10.1016\/j.clcc.2021.11.008_bib0031","article-title":"Trans-lymphatic metastasis in peritoneal dissemination","volume":"S12","author":"Yonemura","year":"2013","journal-title":"J Gastrointest Digest Syst"},{"issue":"6","key":"10.1016\/j.clcc.2021.11.008_bib0032","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s10585-005-2893-8","article-title":"ICAM-1 mediated peritoneal carcinomatosis, a target for therapeutic intervention","volume":"22","author":"Alkhamesi","year":"2005","journal-title":"Clin Exp Metastasis"},{"issue":"4","key":"10.1016\/j.clcc.2021.11.008_bib0033","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1084\/jem.176.4.1165","article-title":"Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells","volume":"176","author":"Jonjic","year":"1992","journal-title":"J Exp Med"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0034","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.3892\/ijo.2017.3953","article-title":"Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression","volume":"50","author":"Liu","year":"2017","journal-title":"Int J Oncol"},{"issue":"10","key":"10.1016\/j.clcc.2021.11.008_bib0035","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1007\/s10620-007-9778-4","article-title":"Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers","volume":"52","author":"van Grevenstein","year":"2007","journal-title":"Dig Dis Sci"},{"issue":"4","key":"10.1016\/j.clcc.2021.11.008_bib0036","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1159\/000163953","article-title":"Effects of cytokines on the expression of cell adhesion molecules by cultured human omental mesothelial cells","volume":"63","author":"Klein","year":"1995","journal-title":"Pathobiology"},{"issue":"7","key":"10.1016\/j.clcc.2021.11.008_bib0037","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1038\/sj.bjc.6601635","article-title":"Tumour-induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas Ligand\/Fas interaction","volume":"90","author":"Heath","year":"2004","journal-title":"Br J Cancer"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0038","first-page":"349","article-title":"A possible role of cytokines in the formation of peritoneal dissemination","volume":"11","author":"Yonemura","year":"1997","journal-title":"Int J Oncol"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0039","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/bjc.1994.290","article-title":"Contribution of host-derived growth factors to in vivo growth of a transplantable murine mammary carcinoma","volume":"70","author":"Davies","year":"1994","journal-title":"Br J Cancer"},{"issue":"6","key":"10.1016\/j.clcc.2021.11.008_bib0040","first-page":"240","article-title":"Association of epidermal growth factor-related peptides and type I receptor tyrosine kinase receptors with prognosis of human colorectal carcinomas","volume":"25","author":"Saeki","year":"1995","journal-title":"Jpn J Clin Oncol"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0041","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","article-title":"Hallmarks of cancer: the next generation","volume":"144","author":"Hanahan","year":"2011","journal-title":"Cell"},{"issue":"34","key":"10.1016\/j.clcc.2021.11.008_bib0042","doi-asserted-by":"crossref","first-page":"7692","DOI":"10.3748\/wjg.v22.i34.7692","article-title":"Pathophysiology of colorectal peritoneal carcinomatosis: role of the peritoneum","volume":"22","author":"Lemoine","year":"2016","journal-title":"World J Gastroenterol"},{"issue":"48","key":"10.1016\/j.clcc.2021.11.008_bib0043","doi-asserted-by":"crossref","first-page":"30081","DOI":"10.1016\/S0021-9258(18)43775-1","article-title":"Intercellular adhesion molecule-1 is a cell surface receptor for hyaluronan","volume":"269","author":"McCourt","year":"1994","journal-title":"J Biol Chem"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0044","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0378-1119(95)00398-P","article-title":"Characterization of the murine gene encoding the hyaluronan receptor RHAMM","volume":"163","author":"Entwistle","year":"1995","journal-title":"Gene"},{"issue":"7","key":"10.1016\/j.clcc.2021.11.008_bib0045","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/0092-8674(90)90694-A","article-title":"CD44 is the principal cell surface receptor for hyaluronate","volume":"61","author":"Aruffo","year":"1990","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0046","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1046\/j.1523-1747.2001.00236.x","article-title":"CD44 is the principal mediator of hyaluronic-acid-induced melanoma cell proliferation","volume":"116","author":"Ahrens","year":"2001","journal-title":"J Invest Dermatol"},{"issue":"10","key":"10.1016\/j.clcc.2021.11.008_bib0047","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1158\/1541-7786.MCR-13-0629","article-title":"CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility","volume":"12","author":"Kim","year":"2014","journal-title":"Mol Cancer Res"},{"key":"10.1016\/j.clcc.2021.11.008_bib0048","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/B978-0-12-800092-2.00002-2","article-title":"Targeting hyaluronic acid family for cancer chemoprevention and therapy","volume":"123","author":"Lokeshwar","year":"2014","journal-title":"Adv Cancer Res"},{"key":"10.1016\/j.clcc.2021.11.008_bib0049","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3389\/fimmu.2015.00182","article-title":"The role of CD44 in disease pathophysiology and targeted treatment","volume":"6","author":"Jordan","year":"2015","journal-title":"Front Immunol"},{"issue":"4","key":"10.1016\/j.clcc.2021.11.008_bib0050","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1136\/mp.51.4.191","article-title":"The normal structure and function of CD44 and its role in neoplasia","volume":"51","author":"Sneath","year":"1998","journal-title":"Mol Pathol"},{"key":"10.1016\/j.clcc.2021.11.008_bib0051","doi-asserted-by":"crossref","first-page":"d616","DOI":"10.2741\/A306","article-title":"CD44 structure and function","volume":"3","author":"Lesley","year":"1998","journal-title":"Front Biosci"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0052","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/jlb.66.2.315","article-title":"Activation and interaction of CD44 and hyaluronan in immunological systems","volume":"66","author":"Siegelman","year":"1999","journal-title":"J Leukoc Biol"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0053","doi-asserted-by":"crossref","first-page":"208","DOI":"10.2174\/187152809788680994","article-title":"CD44 and its role in inflammation and inflammatory diseases","volume":"8","author":"Johnson","year":"2009","journal-title":"Inflamm Allergy Drug Targets"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0054","first-page":"846","article-title":"CD44 is a metastasis suppressor gene for prostatic cancer located on human chromosome 11p13","volume":"57","author":"Gao","year":"1997","journal-title":"Cancer Res"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0055","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/0006-291X(92)91770-Q","article-title":"The complex CD44 transcriptional unit; alternative splicing of three internal exons generates the epithelial form of CD44","volume":"182","author":"Cooper","year":"1992","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0056","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0092-8674(91)90403-L","article-title":"A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells","volume":"65","author":"Gunthert","year":"1991","journal-title":"Cell"},{"issue":"16","key":"10.1016\/j.clcc.2021.11.008_bib0057","doi-asserted-by":"crossref","first-page":"21428","DOI":"10.18632\/oncotarget.7258","article-title":"RHAMM splice variants confer radiosensitivity in human breast cancer cell lines","volume":"7","author":"Schutze","year":"2016","journal-title":"Oncotarget"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0058","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/BF01052625","article-title":"Hyaluronan: RHAMM mediated cell locomotion and signaling in tumorigenesis","volume":"26","author":"Hall","year":"1995","journal-title":"J Neurooncol"},{"issue":"18","key":"10.1016\/j.clcc.2021.11.008_bib0059","doi-asserted-by":"crossref","first-page":"11342","DOI":"10.1074\/jbc.273.18.11342","article-title":"The hyaluronan receptor RHAMM regulates extracellular-regulated kinase","volume":"273","author":"Zhang","year":"1998","journal-title":"J Biol Chem"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0060","first-page":"567","article-title":"The overexpression of RHAMM, a hyaluronan-binding protein that regulates ras signaling, correlates with overexpression of mitogen-activated protein kinase and is a significant parameter in breast cancer progression","volume":"4","author":"Wang","year":"1998","journal-title":"Clin Cancer Res"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0061","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1083\/jcb.126.2.575","article-title":"Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity","volume":"126","author":"Hall","year":"1994","journal-title":"J Cell Biol"},{"key":"10.1016\/j.clcc.2021.11.008_bib0062","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1177\/117727190700200001","article-title":"Induction of proteases in peritoneal carcinomatosis, the Role of ICAM-1\/CD43 interaction","volume":"2","author":"Alkhamesi","year":"2007","journal-title":"Biomark Insights"},{"key":"10.1016\/j.clcc.2021.11.008_bib0063","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.biocel.2017.03.013","article-title":"The protective activity of mesothelial cells against peritoneal growth of gastrointestinal tumors: The role of soluble ICAM-1","volume":"86","author":"Mikula-Pietrasik","year":"2017","journal-title":"Int J Biochem Cell Biol"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0064","first-page":"511","article-title":"Expression of intercellular adhesion molecule-1 and prognosis in colorectal cancer","volume":"9","author":"Maeda","year":"2002","journal-title":"Oncol Rep"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0065","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1083\/jcb.122.1.257","article-title":"Identification of hyaluronic acid binding sites in the extracellular domain of CD44","volume":"122","author":"Peach","year":"1993","journal-title":"J Cell Biol"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0066","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1084\/jem.183.5.1987","article-title":"A cysteine residue located in the transmembrane domain of CD44 is important in binding of CD44 to hyaluronic acid","volume":"183","author":"Liu","year":"1996","journal-title":"J Exp Med"},{"issue":"9","key":"10.1016\/j.clcc.2021.11.008_bib0067","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0138137","article-title":"CD44 binding to hyaluronic acid is redox regulated by a labile disulfide bond in the hyaluronic acid binding site","volume":"10","author":"Kellett-Clarke","year":"2015","journal-title":"PLoS ONE [Electronic Resource]"},{"issue":"5","key":"10.1016\/j.clcc.2021.11.008_bib0068","doi-asserted-by":"crossref","first-page":"e97432","DOI":"10.1371\/journal.pone.0097432","article-title":"Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model","volume":"9","author":"Elliott","year":"2014","journal-title":"PLoS ONE [Electronic Resource]"},{"issue":"32","key":"10.1016\/j.clcc.2021.11.008_bib0069","doi-asserted-by":"crossref","first-page":"33893","DOI":"10.18632\/oncotarget.5294","article-title":"The metastasis suppressor, NDRG1, inhibits \u201cstemness\u201d of colorectal cancer via down-regulation of nuclear beta-catenin and CD44","volume":"6","author":"Wangpu","year":"2015","journal-title":"Oncotarget"},{"issue":"8","key":"10.1016\/j.clcc.2021.11.008_bib0070","doi-asserted-by":"crossref","first-page":"e72849","DOI":"10.1371\/journal.pone.0072849","article-title":"CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status","volume":"8","author":"Zeilstra","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0071","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1159\/000011970","article-title":"Soluble CD44 variant 6 as a prognostic indicator in patients with colorectal cancer","volume":"56","author":"Yamane","year":"1999","journal-title":"Oncology"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0072","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s005350050095","article-title":"Clinical significance of serum levels of CD44 variant exons 8-10 protein in colorectal cancer","volume":"33","author":"Yamaguchi","year":"1998","journal-title":"J Gastroenterol"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0073","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1080\/00365529850166257","article-title":"CD44 splice variants as prognostic markers in colorectal cancer","volume":"33","author":"Wielenga","year":"1998","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.clcc.2021.11.008_bib0074","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1749-6632.1998.tb11151.x","article-title":"CD44 expression in colorectal cancer","volume":"859","author":"Weg-Remers","year":"1998","journal-title":"Ann N Y Acad Sci"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0075","first-page":"239","article-title":"Cancer stem cell marker in circulating tumor cells: expression of CD44 variant exon 9 is strongly correlated to treatment refractoriness, recurrence and prognosis of human colorectal cancer","volume":"35","author":"Katoh","year":"2015","journal-title":"Anticancer Res"},{"issue":"17","key":"10.1016\/j.clcc.2021.11.008_bib0076","first-page":"4427","article-title":"CD44 stimulation induces integrin-mediated adhesion of colon cancer cell lines to endothelial cells by up-regulation of integrins and c-Met and activation of integrins","volume":"59","author":"Fujisaki","year":"1999","journal-title":"Cancer Res"},{"issue":"10","key":"10.1016\/j.clcc.2021.11.008_bib0077","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/ja.2007.81","article-title":"F-19848 A, a novel inhibitor of hyaluronic acid binding to cellular receptor CD44","volume":"60","author":"Hirota-Takahata","year":"2007","journal-title":"J Antibiot"},{"issue":"12","key":"10.1016\/j.clcc.2021.11.008_bib0078","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/ja.2006.102","article-title":"F-16438s, novel binding inhibitors of CD44 and hyaluronic acid. II. Producing organism, fermentation, isolation, physico-chemical properties and structural elucidation","volume":"59","author":"Hirota-Takahata","year":"2006","journal-title":"J Antibiot"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0079","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/0006-291X(82)92101-5","article-title":"Purification of a hyaluronate-binding protein fraction that modifies cell social behavior","volume":"108","author":"Turley","year":"1982","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0080","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0014-4827(85)90486-0","article-title":"Localization of hyaluronate and hyaluronate-binding protein on motile and non-motile fibroblasts","volume":"161","author":"Turley","year":"1985","journal-title":"Exp Cell Res"},{"issue":"11","key":"10.1016\/j.clcc.2021.11.008_bib0081","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.1021\/bi00385a007","article-title":"Characterization of hyaluronate binding proteins isolated from 3T3 and murine sarcoma virus transformed 3T3 cells","volume":"26","author":"Turley","year":"1987","journal-title":"Biochemistry"},{"key":"10.1016\/j.clcc.2021.11.008_bib0082","first-page":"121","article-title":"The role of a cell-associated hyaluronan-binding protein in fibroblast behaviour","volume":"143","author":"Turley","year":"1989","journal-title":"Ciba Found Symp"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0083","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BF00047600","article-title":"Hyaluronan and cell locomotion","volume":"11","author":"Turley","year":"1992","journal-title":"Cancer Metastasis Rev"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0084","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/j.1460-2075.1994.tb06261.x","article-title":"Identification of a common hyaluronan binding motif in the hyaluronan binding proteins RHAMM, CD44 and link protein","volume":"13","author":"Yang","year":"1994","journal-title":"EMBO J"},{"issue":"4","key":"10.1016\/j.clcc.2021.11.008_bib0085","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.3892\/ol.2016.4974","article-title":"Prognostic significance of CD168 overexpression in colorectal cancer","volume":"12","author":"Wang","year":"2016","journal-title":"Oncol Lett"},{"issue":"41","key":"10.1016\/j.clcc.2021.11.008_bib0086","doi-asserted-by":"crossref","first-page":"70617","DOI":"10.18632\/oncotarget.19904","article-title":"The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer","volume":"8","author":"Mele","year":"2017","journal-title":"Oncotarget"},{"issue":"11","key":"10.1016\/j.clcc.2021.11.008_bib0087","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1016\/j.humpath.2015.07.010","article-title":"Expression of the hyaluronan-mediated motility receptor RHAMM in tumor budding cells identifies aggressive colorectal cancers","volume":"46","author":"Koelzer","year":"2015","journal-title":"Hum Pathol"},{"issue":"3","key":"10.1016\/j.clcc.2021.11.008_bib0088","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00428-012-1287-y","article-title":"Understanding molecular mechanisms in peritoneal dissemination of colorectal cancer: future possibilities for personalised treatment by use of biomarkers","volume":"461","author":"de Cuba","year":"2012","journal-title":"Virchows Arch"},{"issue":"1","key":"10.1016\/j.clcc.2021.11.008_bib0089","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00280-010-1303-3","article-title":"Hyaluronan-Irinotecan improves progression-free survival in 5-fluorouracil refractory patients with metastatic colorectal cancer: a randomized phase II trial","volume":"67","author":"Gibbs","year":"2011","journal-title":"Cancer Chemother Pharmacol"},{"year":"2014","series-title":"Trial of FOLF(HA)Iri With Cetuximab in mCRC (Chime)","key":"10.1016\/j.clcc.2021.11.008_bib0090"},{"key":"10.1016\/j.clcc.2021.11.008_bib0091","unstructured":"Clinicaltrials.gov. Trial of FOLF(HA)Iri Versus FOLFIRI in mCRC (FOLF(HA)iri). ClinicalTrials.gov Identifier: NCT01290783. 2015 [cited 2019 10th January 2019]; Available at: https:\/\/clinicaltrials.gov\/ct2\/show\/NCT01290783?id=NCT01290783+OR+NCT02216487&rank=2&load=cart."},{"issue":"26","key":"10.1016\/j.clcc.2021.11.008_bib0092","first-page":"29024","article-title":"Synergy between Intraperitoneal Aerosolization (PIPAC) and cancer nanomedicine: cisplatin-loaded polyarginine-hyaluronic acid nanocarriers efficiently eradicate peritoneal metastasis of advanced human ovarian cancer","volume":"12","author":"Shariati","year":"2020","journal-title":"ACS Appl Mater Interfaces"},{"issue":"7","key":"10.1016\/j.clcc.2021.11.008_bib0093","first-page":"1228","article-title":"In vivo inhibition of CD44 limits intra-abdominal spread of a human ovarian cancer xenograft in nude mice: a novel role for CD44 in the process of peritoneal implantation","volume":"57","author":"Strobel","year":"1997","journal-title":"Cancer Res"},{"issue":"48","key":"10.1016\/j.clcc.2021.11.008_bib0094","doi-asserted-by":"crossref","first-page":"80046","DOI":"10.18632\/oncotarget.11098","article-title":"First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors","volume":"7","author":"Menke-van der Houven van Oordt","year":"2016","journal-title":"Oncotarget"},{"issue":"2","key":"10.1016\/j.clcc.2021.11.008_bib0095","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s00280-003-0626-8","article-title":"Extent of parietal peritonectomy does not change intraperitoneal chemotherapy pharmacokinetics","volume":"52","author":"de Lima Vazquez","year":"2003","journal-title":"Cancer Chemother Pharmacol"}],"container-title":["Clinical Colorectal Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1533002821001304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1533002821001304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T23:09:14Z","timestamp":1761520154000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1533002821001304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":95,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S1533002821001304"],"URL":"https:\/\/doi.org\/10.1016\/j.clcc.2021.11.008","relation":{},"ISSN":["1533-0028"],"issn-type":[{"type":"print","value":"1533-0028"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeting Hyaluronic Acid and Peritoneal Dissemination in Colorectal Cancer","name":"articletitle","label":"Article Title"},{"value":"Clinical Colorectal Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clcc.2021.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}