{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:26:30Z","timestamp":1784204790374,"version":"3.55.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinical-colorectal-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Colorectal Cancer"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.clcc.2022.03.005","type":"journal-article","created":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T12:40:27Z","timestamp":1654260027000},"page":"e213-e225","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Prognostic Role of Low-Skeletal Muscle Mass on Staging Computed Tomography in Metastasized Colorectal Cancer: A Systematic Review and Meta-Analysis"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8489-706X","authenticated-orcid":false,"given":"Hans-Jonas","family":"Meyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Strobel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Wienke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey","family":"Surov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clcc.2022.03.005_bib0001","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S1470-2045(08)70153-0","article-title":"Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study","volume":"9","author":"Prado","year":"2008","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0002","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jamda.2011.01.003","article-title":"Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia","volume":"12","author":"Fielding","year":"2011","journal-title":"J Am Med Dir Assoc"},{"key":"10.1016\/j.clcc.2022.03.005_bib0003","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1447-0594.2012.00851.x","article-title":"Sarcopenia in the elderly: basic and clinical issues","volume":"12","author":"Wang","year":"2012","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.clcc.2022.03.005_bib0004","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.cger.2011.03.004","article-title":"The epidemiology of sarcopenia","volume":"27","author":"Janssen","year":"2011","journal-title":"Clin Geriatr Med"},{"key":"10.1016\/j.clcc.2022.03.005_bib0005","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.21873\/anticanres.14210","article-title":"Skeletal muscle mass change during chemotherapy: a systematic review and meta-analysis","volume":"40","author":"Jang","year":"2020","journal-title":"Anticancer Res"},{"key":"10.1016\/j.clcc.2022.03.005_bib0006","first-page":"1","article-title":"Sarcopenia: imaging assessment and clinical application","author":"Chianca","year":"2021","journal-title":"Abdom Radiol (NY)"},{"key":"10.1016\/j.clcc.2022.03.005_bib0007","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1055\/s-0040-1708824","article-title":"Quantitative imaging of body composition","volume":"24","author":"Hemke","year":"2020","journal-title":"Semin Musculoskelet Radiol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0008","doi-asserted-by":"crossref","first-page":"7964","DOI":"10.1002\/cam4.3428","article-title":"Sarcopenia and adverse health-related outcomes: an umbrella review of meta-analyses of observational studies","volume":"9","author":"Xia","year":"2020","journal-title":"Cancer Med"},{"key":"10.1016\/j.clcc.2022.03.005_bib0009","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.3390\/cancers11121861","article-title":"Cachexia and sarcopenia in older adults with cancer: a comprehensive review","volume":"11","author":"Dunne","year":"2019","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.clcc.2022.03.005_bib0010","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol"},{"issue":"Suppl 1","key":"10.1016\/j.clcc.2022.03.005_bib0011","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1016\/j.afos.2021.02.005","article-title":"Different definition of sarcopenia and mortality in cancer: a meta-analysis","volume":"7","author":"Li","year":"2021","journal-title":"Osteoporos Sarcopenia"},{"key":"10.1016\/j.clcc.2022.03.005_bib0012","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1200\/JCO.2012.45.2722","article-title":"Cancer cachexia in the age of obesity: skeletal muscle depletion is a powerful prognostic factor, independent of body mass index","volume":"31","author":"Martin","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0013","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1080\/01635581.2012.670743","article-title":"Malnutrition is high and underestimated during chemotherapy in gastrointestinal cancer: an AGEO prospective cross-sectional multicenter study","volume":"64","author":"Attar","year":"2012","journal-title":"Nutr Cancer"},{"key":"10.1016\/j.clcc.2022.03.005_bib0014","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLOS Med"},{"key":"10.1016\/j.clcc.2022.03.005_bib0015","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1080\/01635581.2014.894103","article-title":"Sarcopenia is linked to treatment toxicity in patients with metastatic colorectal cancer","volume":"66","author":"Barret","year":"2014","journal-title":"Nutr Cancer"},{"key":"10.1016\/j.clcc.2022.03.005_bib0016","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/s12885-019-5319-8","article-title":"Prognostic value of adipose tissue and muscle mass in advanced colorectal cancer: a post hoc analysis of two non-randomized phase II trials","volume":"19","author":"Charette","year":"2019","journal-title":"BMC Cancer"},{"key":"10.1016\/j.clcc.2022.03.005_bib0017","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.1245\/s10434-016-5360-7","article-title":"Sarcopenia is associated with chemotherapy toxicity in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from colorectal cancer","volume":"23","author":"Chemama","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0018","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.clnesp.2019.04.004","article-title":"Sarcopenia as an independent prognostic factor in patients with metastatic colorectal cancer: a retrospective evaluation","volume":"32","author":"da Cunha","year":"2019","journal-title":"Clin Nutr ESPEN"},{"key":"10.1016\/j.clcc.2022.03.005_bib0019","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2021.671547","article-title":"Impact of body composition on prognosis and dose-limiting toxicities on metastatic colorectal cancer","volume":"8","author":"da Silva Dias","year":"2022","journal-title":"Front Nutr"},{"key":"10.1016\/j.clcc.2022.03.005_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinre.2020.101603","article-title":"Skeletal muscle loss during chemotherapy and its association with survival and systemic treatment toxicity in metastatic colorectal cancer: An AGEO prospective multicenter study","volume":"45","author":"Gallois","year":"2021","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0021","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1007\/s12094-019-02080-4","article-title":"Relation between sarcopenia and dose-limiting toxicity in patients with metastatic colorectal cancer who received regorafenib","volume":"21","author":"G\u00f6kyer","year":"2019","journal-title":"Clin Transl Oncol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0022","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s12957-020-01836-5","article-title":"Impact of intramuscular adipose tissue content on short- and long-term outcomes of hepatectomy for colorectal liver metastasis: a retrospective analysis","volume":"18","author":"Horii","year":"2020","journal-title":"World J Surg Oncol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0023","first-page":"159","article-title":"Regorafenib is associated with increased skeletal muscle loss compared to TAS-102 in metastatic colorectal cancer","volume":"18","author":"Huemer","year":"2019","journal-title":"Clin Colorectal Cancer"},{"key":"10.1016\/j.clcc.2022.03.005_bib0024","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1002\/jcsm.12436","article-title":"Skeletal muscle mass loss and dose-limiting toxicities in metastatic colorectal cancer patients","volume":"10","author":"Kurk","year":"2019","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.clcc.2022.03.005_bib0025","doi-asserted-by":"crossref","first-page":"6459","DOI":"10.1038\/s41598-020-63644-x","article-title":"Prognostic value of sarcopenia in patients with colorectal liver metastases undergoing hepatic resection","volume":"10","author":"Liu","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.clcc.2022.03.005_bib0026","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/hpb.12373","article-title":"Are sarcopenia, obesity and sarcopenic obesity predictive of outcome in patients with colorectal liver metastases?","volume":"17","author":"Lodewick","year":"2015","journal-title":"HPB (Oxford)"},{"key":"10.1016\/j.clcc.2022.03.005_bib0027","doi-asserted-by":"crossref","first-page":"355","DOI":"10.5306\/wjco.v12.i5.355","article-title":"Prognostic role of sarcopenia in metastatic colorectal cancer patients during first-line chemotherapy: A retrospective study","volume":"12","author":"Maddalena","year":"2021","journal-title":"World J Clin Oncol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0028","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1007\/s10147-019-01460-8","article-title":"Skeletal muscle loss during systemic chemotherapy for colorectal cancer indicates treatment response: a pooled analysis of a multicenter clinical trial (KSCC 1605-A)","volume":"24","author":"Sasaki","year":"2019","journal-title":"Int J Clin Oncol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0029","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00280-017-3487-2","article-title":"The impact of skeletal muscle on the pharmacokinetics and toxicity of 5-fluorouracil in colorectal cancer","volume":"81","author":"Williams","year":"2018","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0030","unstructured":"Wells GA, Shea B, O'Connell D, et\u00a0al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses - 2008. Available at: http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp. Accessed: April 2021."},{"key":"10.1016\/j.clcc.2022.03.005_bib0031","doi-asserted-by":"crossref","first-page":"889","DOI":"10.7326\/0003-4819-149-12-200812160-00008","article-title":"Systematic reviews of diagnostic test accuracy","volume":"149","author":"Leeflang","year":"2008","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.clcc.2022.03.005_bib0032","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1471-2288-6-31","article-title":"Meta-DiSc: a software for meta-analysis of test accuracy data","volume":"6","author":"Zamora","year":"2006","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.clcc.2022.03.005_bib0033","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.clcc.2022.03.005_bib0034","doi-asserted-by":"crossref","first-page":"5298","DOI":"10.1016\/j.clnu.2021.08.023","article-title":"Low skeletal muscle mass is a predictor of treatment related toxicity in oncologic patients. A meta-analysis","volume":"40","author":"Surov","year":"2021","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clcc.2022.03.005_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.archger.2021.104534","article-title":"Impact of preoperative sarcopenia on postoperative complications and prognosis of gastric cancer resection: a meta-analysis of cohort studies","volume":"98","author":"Chen","year":"2022","journal-title":"Arch Gerontol Geriatr"},{"key":"10.1016\/j.clcc.2022.03.005_bib0036","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000494887","article-title":"Computed tomography-assessed sarcopenia indexes predict major complications following surgery for hepatopancreatobiliary malignancy: a meta-analysis","volume":"74","author":"Cao","year":"2019","journal-title":"Ann Nutr Metab"},{"issue":"10","key":"10.1016\/j.clcc.2022.03.005_bib0037","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s00384-018-3128-1","article-title":"Can sarcopenia be a predictor of prognosis for patients with non-metastatic colorectal cancer? A systematic review and meta-analysis","volume":"33","author":"Sun","year":"2018","journal-title":"Int J Colorectal Dis"}],"container-title":["Clinical Colorectal Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1533002822000688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1533002822000688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T23:09:12Z","timestamp":1761520152000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1533002822000688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S1533002822000688"],"URL":"https:\/\/doi.org\/10.1016\/j.clcc.2022.03.005","relation":{},"ISSN":["1533-0028"],"issn-type":[{"value":"1533-0028","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic Role of Low-Skeletal Muscle Mass on Staging Computed Tomography in Metastasized Colorectal Cancer: A Systematic Review and Meta-Analysis","name":"articletitle","label":"Article Title"},{"value":"Clinical Colorectal Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clcc.2022.03.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}