{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T14:03:11Z","timestamp":1648821791005},"reference-count":68,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","clinicalkey.com.au","clinicalkey.fr","liver.theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Liver Disease"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.cld.2015.04.007","type":"journal-article","created":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T01:12:22Z","timestamp":1433466742000},"page":"473-485","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Covert Hepatic Encephalopathy"],"prefix":"10.1016","volume":"19","author":[{"given":"Steven L.","family":"Flamm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cld.2015.04.007_bib1","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/S0168-8278(01)00026-5","article-title":"Neuropsychological characterization of hepatic encephalopathy","volume":"34","author":"Weissenborn","year":"2001","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib2","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s11011-005-7922-4","article-title":"Impairment of response inhibition precedes motor alteration in the early stage of liver cirrhosis: a behavioral electrophysiological study","volume":"20","author":"Schiff","year":"2005","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.cld.2015.04.007_bib3","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jhep.2005.06.013","article-title":"Neuropsychological abnormalities in cirrhosis include learning impairment","volume":"44","author":"Ortiz","year":"2006","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib4","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s11011-005-7919-z","article-title":"Attention, memory and cognitive function in hepatic encephalopathy","volume":"20","author":"Weissenborn","year":"2005","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.cld.2015.04.007_bib5","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/hep.510280108","article-title":"Subclinical hepatic encephalopathy impairs daily functioning","volume":"28","author":"Groeneweg","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib6","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1023\/A:1011610427843","article-title":"Quality of life in cirrhotics with minimal hepatic encephalopathy","volume":"16","author":"Schomerus","year":"2001","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.cld.2015.04.007_bib7","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1023\/A:1024784327783","article-title":"Influence of hepatic encephalopathy on health-related quality of life in patients with cirrhosis","volume":"48","author":"Arguedas","year":"2003","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.cld.2015.04.007_bib8","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.cld.2011.12.003","article-title":"Hepatic encephalopathy and health-related quality of life","volume":"16","author":"Bianchi","year":"2012","journal-title":"Clin Liver Dis"},{"key":"10.1016\/j.cld.2015.04.007_bib9","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1038\/ajg.2010.413","article-title":"Minimal hepatic encephalopathy is associated with falls","volume":"106","author":"Roman","year":"2011","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib10","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1002\/hep.20095","article-title":"Minimal hepatic encephalopathy impairs fitness to drive","volume":"39","author":"Wein","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib11","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1111\/j.1572-0241.2007.01424.x","article-title":"Minimal hepatic encephalopathy: a vehicle for accidents and traffic violations","volume":"102","author":"Bajaj","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib12","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1002\/hep.22032","article-title":"Navigation skill impairment: another dimension of the driving difficulties in minimal hepatic encephalopathy","volume":"47","author":"Bajaj","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib13","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/hep.23128","article-title":"Minimal hepatic encephalopathy is associated with motor vehicle crashes: the reality beyond the driving test","volume":"50","author":"Bajaj","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib14","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1111\/j.1572-0241.2001.04130.x","article-title":"Subclinical hepatic encephalopathy predicts the development of overt hepatic encephalopathy","volume":"96","author":"Romero-Gomez","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib15","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1111\/j.1572-0241.2000.02265.x","article-title":"The prognostic significance of subclinical hepatic encephalopathy","volume":"95","author":"Hartman","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib16","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1038\/ajg.2014.264","article-title":"Covert and hepatic encephalopathy is independently associated with poor survival and increased risk of hospitalization","volume":"109","author":"Patidar","year":"2014","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib17","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1053\/jhep.2002.31250","article-title":"Hepatic encephalopathy \u2013 definition, nomenclature, diagnosis, and quantification. Final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998","volume":"35","author":"Ferenci","year":"2002","journal-title":"Hepatology"},{"issue":"suppl","key":"10.1016\/j.cld.2015.04.007_bib18","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1016\/j.jhep.2004.11.028","article-title":"Minimal hepatic encephalopathy: diagnosis, clinical significance and recommendations","volume":"42","author":"Ortiz","year":"2005","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib19","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.3748\/wjg.v10.i16.2397","article-title":"Prevalence of subclinical hepatic encephalopathy in cirrhotic patients in China","volume":"10","author":"Li","year":"2004","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib20","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1111\/j.1572-0241.2001.03964.x","article-title":"Hepatic encephalopathy","volume":"96","author":"Blei","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib21","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-mental state: a practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J\u00a0Psychiatr Res"},{"key":"10.1016\/j.cld.2015.04.007_bib22","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s11011-006-9042-1","article-title":"Role of ammonia and inflammation in minimal hepatic encephalopathy","volume":"22","author":"Shawcross","year":"2007","journal-title":"Metab Brain Dis"},{"issue":"1","key":"10.1016\/j.cld.2015.04.007_bib23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.cld.2011.12.002","article-title":"Assessment of minimal hepatic encephalopathy (with emphasis on computerized psychometric tests)","volume":"16","author":"Kappus","year":"2012","journal-title":"Clin Liver Dis"},{"issue":"9","key":"10.1016\/j.cld.2015.04.007_bib24","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1016\/j.clinthera.2013.07.421","article-title":"Evolving concepts: the negative effect of minimal hepatic encephalopathy and role for prophylaxis in patients with cirrhosis","volume":"35","author":"Prakash","year":"2013","journal-title":"Clin Ther"},{"key":"10.1016\/j.cld.2015.04.007_bib25","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1055\/s-2007-984576","article-title":"An algorithm for the management of hepatic encephalopathy","volume":"27","author":"Mullen","year":"2007","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.cld.2015.04.007_bib26","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1478-3231.2009.02009.x","article-title":"Neuropsychological assessment of hepatic encephalopathy: ISHEN practice guidelines","volume":"29","author":"Randolph","year":"2009","journal-title":"Liver Int"},{"key":"10.1016\/j.cld.2015.04.007_bib27","doi-asserted-by":"crossref","first-page":"3014","DOI":"10.1007\/s10620-011-1684-0","article-title":"Validation of the psychometric hepatic encephalopathy score (PHES) for identifying patients with minimal hepatic encephalopathy","volume":"56","author":"Duarte-Rojo","year":"2011","journal-title":"Dig Dis Sci"},{"issue":"6","key":"10.1016\/j.cld.2015.04.007_bib28","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1586\/17474124.2.6.785","article-title":"Management options for minimal hepatic encephalopathy","volume":"2","author":"Bajaj","year":"2008","journal-title":"Expert Rev Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.cld.2015.04.007_bib29","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1440-1819.2006.01483.x","article-title":"Cognitive impairment in people diagnosed with end-stage liver disease evaluated for liver transplantation","volume":"60","author":"Sorrell","year":"2006","journal-title":"Psychiatry Clin Neurosci"},{"key":"10.1016\/j.cld.2015.04.007_bib30","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.acn.2006.12.005","article-title":"Utility of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in patients with end-stage liver disease awaiting liver transplant","volume":"22","author":"Mooney","year":"2007","journal-title":"Arch Clin Neuropsychol"},{"key":"10.1016\/j.cld.2015.04.007_bib31","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1053\/j.gastro.2008.07.021","article-title":"Inhibitory control test for the diagnosis of minimal hepatic encephalopathy","volume":"135","author":"Bajaj","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cld.2015.04.007_bib32","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1002\/hep.26309","article-title":"The Stroop smartphone application is a short and valid method to screen for minimal hepatic encephalopathy","volume":"58","author":"Bajaj","year":"2013","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib33","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/S0168-8278(00)80110-5","article-title":"Hepatic encephalopathy in chronic liver disease: a clinical manifestation of astrocyte swelling and low grade cerebral edema","volume":"32","author":"Haussinger","year":"2000","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib34","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1002\/hep.21586","article-title":"Value of the critical flicker frequency in patients with minimal hepatic encephalopathy","volume":"45","author":"Romero-Gomez","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib35","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1053\/jhep.2002.30957","article-title":"Critical flicker frequency for quantification of low-grade hepatic encephalopathy","volume":"35","author":"Kircheis","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib36","first-page":"27","article-title":"Critical flicker frequency for diagnosis and assessment of recovery from minimal hepatic encephalopathy in patients with cirrhosis","volume":"9","author":"Sharma","year":"2010","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10.1016\/j.cld.2015.04.007_bib37","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/S0140-6736(57)90005-3","article-title":"The electroencephalograph in liver disease","volume":"273","author":"Parsons-Smith","year":"1957","journal-title":"Lancet"},{"key":"10.1016\/j.cld.2015.04.007_bib38","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0168-8278(01)00129-5","article-title":"Prevalence and prognostic value of quantified electroencephalogram (EEG) alterations in cirrhotic patients","volume":"35","author":"Amodio","year":"2001","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib39","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.jhep.2006.10.015","article-title":"Spatio-temporal decomposition of the electroencephalogram in patients with cirrhosis","volume":"46","author":"Montagnese","year":"2007","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib40","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.jhep.2008.04.022","article-title":"Detection of minimal hepatic encephalopathy: normalization and optimization of the psychometric hepatic encephalopathy score. A neuropsychological and quantified EEG study","volume":"49","author":"Amodio","year":"2008","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib41","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1046\/j.1440-1746.2001.02388.x","article-title":"Auditory P300 event-related potentials and number connection test for evaluation of subclinical hepatic encephalopathy in patients with cirrhosis of the liver: a follow-up study","volume":"16","author":"Saxena","year":"2001","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib42","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF02081027","article-title":"Pallidal lesions in patients with liver cirrhosis: clinical and MRI evaluation","volume":"10","author":"Weissenborn","year":"1995","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.cld.2015.04.007_bib43","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1148\/radiology.216.3.r00se27683","article-title":"MR imaging and (1) H spectroscopy of brain metabolites in hepatic encephalopathy: time-course of renormalization after liver transplantation","volume":"216","author":"Naegele","year":"2000","journal-title":"Radiology"},{"key":"10.1016\/j.cld.2015.04.007_bib44","first-page":"170","article-title":"SPECT scan and cognitive findings in subclinical hepatic encephalopathy","volume":"6","author":"Trzepacz","year":"1994","journal-title":"J\u00a0Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.cld.2015.04.007_bib45","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1023\/A:1014000313824","article-title":"Correlations between cerebral glucose metabolism and neuropsychological test performance in nonalcoholic cirrhotics","volume":"17","author":"Lockwood","year":"2002","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.cld.2015.04.007_bib46","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/hep.21533","article-title":"Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy","volume":"45","author":"Prasad","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib47","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/0168-8278(89)90009-3","article-title":"Lactitol and lactulose for the treatment of subclinical hepatic encephalopathy in cirrhotic patients. A randomised, cross-over study","volume":"8","author":"Morgan","year":"1989","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib48","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1002\/hep.510260606","article-title":"Clinical efficacy of lactulose in cirrhotic patients with and without subclinical hepatic encephalopathy","volume":"26","author":"Watanabe","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib49","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1046\/j.1365-2036.1997.118289000.x","article-title":"Lactulose improves psychometric testing in cirrhotic patients with subclinical encephalopathy","volume":"11","author":"Horsmans","year":"1997","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cld.2015.04.007_bib50","first-page":"1126","article-title":"Effects of lactulose treatment on the course of subclinical hepatic encephalopathy","volume":"83","author":"Zeng","year":"2003","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"10.1016\/j.cld.2015.04.007_bib51","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/j.1365-2036.2010.04574.x","article-title":"Meta-analysis: the effects of gut flora modulation using prebiotics, probiotics and synbiotics on minimal hepatic encephalopathy","volume":"33","author":"Shukla","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cld.2015.04.007_bib52","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1056\/NEJMe1000850","article-title":"Gut flora and hepatic encephalopathy in patients with cirrhosis","volume":"362","author":"Riordan","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cld.2015.04.007_bib53","doi-asserted-by":"crossref","first-page":"3347","DOI":"10.3748\/wjg.v16.i27.3347","article-title":"Changing face of hepatic encephalopathy: role of inflammation and oxidative stress","volume":"16","author":"Seyan","year":"2010","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib54","doi-asserted-by":"crossref","first-page":"805","DOI":"10.7326\/0003-4819-142-10-200505170-00005","article-title":"A\u00a0randomized, double-blind, placebo-controlled trial of rifaximin to prevent travelers' diarrhea","volume":"142","author":"DuPont","year":"2005","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.cld.2015.04.007_bib55","unstructured":"Xifaxan (rifaximin) tablets [package insert]. Raleigh, NC: Salix Pharmaceuticals, Inc; 2012."},{"key":"10.1016\/j.cld.2015.04.007_bib56","doi-asserted-by":"crossref","first-page":"e60042","DOI":"10.1371\/journal.pone.0060042","article-title":"Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy","volume":"8","author":"Bajaj","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.cld.2015.04.007_bib57","first-page":"290","article-title":"Effects of rifaximin administration on the intestinal microbiota in patients with ulcerative colitis","volume":"14","author":"Brigidi","year":"2002","journal-title":"J\u00a0Chemother"},{"key":"10.1016\/j.cld.2015.04.007_bib58","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1056\/NEJMoa0907893","article-title":"Rifaximin treatment in hepatic encephalopathy","volume":"362","author":"Bass","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cld.2015.04.007_bib59","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/ajg.2010.455","article-title":"Rifaximin improves psychometric performance and health-related quality of life in patients with minimal hepatic encephalopathy (the RIME Trial)","volume":"106","author":"Sidhu","year":"2011","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib60","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1053\/j.gastro.2010.08.061","article-title":"Rifaximin improves driving simulator performance in a randomized trial of patients with minimal hepatic encephalopathy","volume":"140","author":"Bajaj","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cld.2015.04.007_bib61","first-page":"128","article-title":"A\u00a0randomized double blind placebo controlled trial of probiotics in minimal hepatic encephalopathy","volume":"32","author":"Saji","year":"2011","journal-title":"Trop Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib62","first-page":"215","article-title":"Effect of administration of Escherichia coli Nissle (Mutaflor) on intestinal colonisation, endo-toxemia, liver function and minimal hepatic encephalopathy in patients with liver cirrhosis","volume":"52","author":"Lata","year":"2006","journal-title":"Vnitr Lek"},{"key":"10.1016\/j.cld.2015.04.007_bib63","doi-asserted-by":"crossref","first-page":"3259","DOI":"10.1007\/s10620-006-9687-y","article-title":"Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study","volume":"52","author":"Malaguarnera","year":"2007","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.cld.2015.04.007_bib64","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1097\/MEG.0b013e3282f3e6f5","article-title":"An open-label randomized controlled trial of lactulose and probiotics in the treatment of minimal hepatic encephalopathy","volume":"20","author":"Sharma","year":"2008","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.cld.2015.04.007_bib65","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1111\/j.1572-0241.2008.01861.x","article-title":"Probiotic yogurt for the treatment of minimal hepatic encephalopathy","volume":"103","author":"Bajaj","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cld.2015.04.007_bib66","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/hep.20194","article-title":"Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis","volume":"39","author":"Liu","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2015.04.007_bib67","first-page":"544","article-title":"Is it a medical error if we do not screen cirrhotic patients for minimal hepatic encephalopathy?","volume":"94","author":"Quero Guillen","year":"2002","journal-title":"Rev Esp Enferm Dig"},{"key":"10.1016\/j.cld.2015.04.007_bib68","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/ncpgasthep0999","article-title":"Minimal hepatic encephalopathy","volume":"4","author":"Stewart","year":"2007","journal-title":"Nat Clin Pract Gastroenterol Hepatol"}],"container-title":["Clinics in Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089326115000392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089326115000392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T05:21:32Z","timestamp":1537593692000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089326115000392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":68,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S1089326115000392"],"URL":"https:\/\/doi.org\/10.1016\/j.cld.2015.04.007","relation":{},"ISSN":["1089-3261"],"issn-type":[{"value":"1089-3261","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Covert Hepatic Encephalopathy","name":"articletitle","label":"Article Title"},{"value":"Clinics in Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cld.2015.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}