{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:18:11Z","timestamp":1774952291551,"version":"3.50.1"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Liver Disease"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.cld.2023.01.021","type":"journal-article","created":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T17:50:10Z","timestamp":1680717010000},"page":"515-533","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Physicians' Use of Digital Health Interventions in the Management of Nonalcoholic Fatty Liver Disease"],"prefix":"10.1016","volume":"27","author":[{"given":"Jeffrey V.","family":"Lazarus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela","family":"Villota-Rivas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Jim\u00e9nez-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro","family":"Santos-Laso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Iruzubieta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Teresa","family":"Arias-Loste","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Rice-Duek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Leigh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J.","family":"Kopka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Turnes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"Calleja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Crespo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cld.2023.01.021_bib1","author":"World Health Organization"},{"key":"10.1016\/j.cld.2023.01.021_bib2","author":"World Health Organization"},{"issue":"2","key":"10.1016\/j.cld.2023.01.021_bib3","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.eprac.2021.12.010","article-title":"Fatty liver through the ages: nonalcoholic steatohepatitis","volume":"28","author":"Younossi","year":"2022","journal-title":"Endocr Pract"},{"key":"10.1016\/j.cld.2023.01.021_bib4","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s11901-017-0378-2","article-title":"Natural history of NAFLD\/NASH","volume":"16","author":"Ekstedt","year":"2017","journal-title":"Curr Hepatol Rep"},{"issue":"1","key":"10.1016\/j.cld.2023.01.021_bib5","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/hep.29466","article-title":"Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease","volume":"67","author":"Estes","year":"2018","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2023.01.021_bib6","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/liv.13643","article-title":"Global epidemiology of non-alcoholic fatty liver disease\/non-alcoholic steatohepatitis: what we need in the future Fondazione Italiana Fegato-Onlus, Trieste, Italy","volume":"38","author":"Ruth Ara\u00fajo","year":"2018","journal-title":"Liver Int"},{"issue":"6","key":"10.1016\/j.cld.2023.01.021_bib7","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1053\/j.gastro.2018.08.024","article-title":"Risk of hepatocellular cancer in patients with non-alcoholic fatty liver disease","volume":"155","author":"Kanwal","year":"2018","journal-title":"Gastroenterology"},{"issue":"12","key":"10.1016\/j.cld.2023.01.021_bib8","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1001\/jamaoncol.2019.2996","article-title":"Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: a systematic analysis for the global burden of disease study","volume":"5","author":"Fitzmaurice","year":"2019","journal-title":"JAMA Oncol"},{"issue":"6","key":"10.1016\/j.cld.2023.01.021_bib9","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1002\/hep.30251","article-title":"Global perspectives on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis","volume":"69","author":"Younossi","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2023.01.021_bib10","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.jhep.2017.05.016","article-title":"Treatment of NAFLD with diet, physical activity and exercise","volume":"67","author":"Romero-G\u00f3mez","year":"2017","journal-title":"J\u00a0Hepatol"},{"issue":"6","key":"10.1016\/j.cld.2023.01.021_bib11","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.jhepr.2019.10.008","article-title":"Lifestyle modification in NAFLD\/NASH: facts and figures","volume":"1","author":"Hallsworth","year":"2019","journal-title":"JHEP Reports"},{"key":"10.1016\/j.cld.2023.01.021_bib12","author":"Internet"},{"issue":"8","key":"10.1016\/j.cld.2023.01.021_bib14","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-037643","article-title":"Identifying optimal frameworks to implement or evaluate digital health interventions: a scoping review protocol","volume":"10","author":"Soobiah","year":"2020","journal-title":"BMJ Open"},{"issue":"10","key":"10.1016\/j.cld.2023.01.021_bib15","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2021-053891","article-title":"Web-based internet searches for digital health products in the United Kingdom before and during the COVID-19 pandemic: a time-series analysis using app libraries from the Organisation for the Review of Care and Health Applications (ORCHA)","volume":"11","author":"Leigh","year":"2021","journal-title":"BMJ Open"},{"key":"10.1016\/j.cld.2023.01.021_bib16","first-page":"120","article-title":"The effectiveness of self-guided digital interventions to improve physical activity and exercise outcomes for people with chronic conditions: a systematic review and meta-analysis","volume":"0","author":"Stavric","year":"2022","journal-title":"Front Rehabil Sci"},{"issue":"3","key":"10.1016\/j.cld.2023.01.021_bib17","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1002\/hep.32329","article-title":"The digital transformation of hepatology: the patient is logged in","volume":"75","author":"Wu","year":"2022","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.cld.2023.01.021_bib18","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/oby.23088","article-title":"Self-monitoring via digital health in weight loss interventions: a systematic review among adults with overweight or obesity","volume":"29","author":"Patel","year":"2021","journal-title":"Obesity"},{"issue":"3","key":"10.1016\/j.cld.2023.01.021_bib19","doi-asserted-by":"crossref","DOI":"10.2196\/21061","article-title":"Digital technology interventions for risk factor modification in patients with cardiovascular disease: systematic review and meta-analysis","volume":"9","author":"Akinosun","year":"2021","journal-title":"JMIR Mhealth and Uhealth"},{"issue":"2","key":"10.1016\/j.cld.2023.01.021_bib20","article-title":"Clinical improvements by telemedicine interventions managing type 1 and type 2 diabetes: systematic meta-review","volume":"23","author":"Eberle","year":"2021","journal-title":"J\u00a0Med Internet Res"},{"key":"10.1016\/j.cld.2023.01.021_bib21","author":"Digital"},{"issue":"7","key":"10.1016\/j.cld.2023.01.021_bib22","doi-asserted-by":"crossref","DOI":"10.2196\/17704","article-title":"Barriers and facilitators to the adoption of mobile health among health care professionals from the United Kingdom: discrete choice experiment","volume":"8","author":"Leigh","year":"2020","journal-title":"JMIR Mhealth and Uhealth"},{"issue":"2","key":"10.1016\/j.cld.2023.01.021_bib23","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1016\/S2589-7500(19)30025-1","article-title":"The role of health-care providers in mHealth adoption","volume":"1","author":"Leigh","year":"2019","journal-title":"Lancet Digit Heal"},{"issue":"4","key":"10.1016\/j.cld.2023.01.021_bib24","first-page":"225","article-title":"Visi\u00f3n ciudadana sobre la prescripci\u00f3n de aplicaciones m\u00f3viles de salud y el uso de tecnolog\u00edas de la informaci\u00f3n y la comunicaci\u00f3n en el entorno sanitario en Andaluc\u00eda","volume":"33","author":"Sotillos-Gonz\u00e1lez","year":"2018","journal-title":"J\u00a0Healthc Qual Res"},{"issue":"1","key":"10.1016\/j.cld.2023.01.021_bib26","doi-asserted-by":"crossref","first-page":"107","DOI":"10.17811\/rifie.47.1.2018.107-112","article-title":"Mobile applications for the elderly: a study of their current strategy","volume":"47","author":"O\u00f1ate","year":"2018","journal-title":"Aula Abierta"},{"issue":"1","key":"10.1016\/j.cld.2023.01.021_bib28","doi-asserted-by":"crossref","first-page":"e20491","DOI":"10.2196\/20491","article-title":"Digital intervention with lifestyle coach support to target dietary and physical activity behaviors of adults with nonalcoholic fatty liver disease: systematic development process of VITALISE using intervention mapping","volume":"23","author":"Hallsworth","year":"2021","journal-title":"J\u00a0Med Internet Res"},{"issue":"4","key":"10.1016\/j.cld.2023.01.021_bib29","doi-asserted-by":"crossref","first-page":"e14802","DOI":"10.2196\/14802","article-title":"Lifestyle intervention enabled by mobile technology on weight loss in patients with nonalcoholic fatty liver disease: randomized controlled trial","volume":"8","author":"Lim","year":"2020","journal-title":"JMIR Mhealth and Uhealth"},{"issue":"4","key":"10.1016\/j.cld.2023.01.021_bib30","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.jhep.2018.05.036","article-title":"Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016\u20132030","volume":"69","author":"Estes","year":"2018","journal-title":"J\u00a0Hepatol"},{"issue":"1","key":"10.1016\/j.cld.2023.01.021_bib31","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jhep.2019.08.027","article-title":"A\u00a0cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe","volume":"72","author":"Lazarus","year":"2020","journal-title":"J\u00a0Hepatol"},{"issue":"2","key":"10.1016\/j.cld.2023.01.021_bib32","doi-asserted-by":"crossref","first-page":"100234","DOI":"10.1016\/j.jhepr.2021.100234","article-title":"European \u2018NAFLD Preparedness Index\u2019 \u2014 is Europe ready to meet the challenge of fatty liver disease?","volume":"3","author":"Lazarus","year":"2021","journal-title":"JHEP Reports"},{"issue":"4","key":"10.1016\/j.cld.2023.01.021_bib33","first-page":"771","article-title":"The global NAFLD policy review and preparedness index: are countries ready to address this silent public health challenge?","volume":"76","author":"Lazarus","year":"2022","journal-title":"JHEP"},{"issue":"S 01","key":"10.1016\/j.cld.2023.01.021_bib34","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.15265\/IYS-2016-s006","article-title":"Electronic health records: then, now, and in the future","volume":"25","author":"Evans","year":"2016","journal-title":"Yearb Med Inform"},{"issue":"3","key":"10.1016\/j.cld.2023.01.021_bib35","doi-asserted-by":"crossref","DOI":"10.5210\/ojphi.v4i3.4304","article-title":"Prescribing: history, issues, and potentials","volume":"4","author":"Salmon","year":"2012","journal-title":"Online J Public Health Inform"},{"key":"10.1016\/j.cld.2023.01.021_bib37","series-title":"Digitalization in healthcare. Implementing innovation and artificial intelligence","author":"Glauner","year":"2021"},{"key":"10.1016\/j.cld.2023.01.021_bib38","author":"Johns"},{"issue":"6","key":"10.1016\/j.cld.2023.01.021_bib39","doi-asserted-by":"crossref","first-page":"e37677","DOI":"10.2196\/37677","article-title":"Assessing the clinical robustness of digital health startups: cross-sectional observational analysis","volume":"24","author":"Day","year":"2022","journal-title":"J\u00a0Med Internet Res"},{"key":"10.1016\/j.cld.2023.01.021_bib40","author":"NHS Apps Library - NHS Digital"},{"issue":"1","key":"10.1016\/j.cld.2023.01.021_bib41","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1093\/jamia\/ocv052","article-title":"m-Health adoption by healthcare professionals: a systematic review","volume":"23","author":"Gagnon","year":"2016","journal-title":"J\u00a0Am Med Informatics Assoc"},{"issue":"4\u20135","key":"10.1016\/j.cld.2023.01.021_bib42","first-page":"345","article-title":"Preparing nurses to be prescribers of digital therapeutics","volume":"54","author":"Ferguson","year":"2018"}],"container-title":["Clinics in Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089326123000211?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089326123000211?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T18:00:17Z","timestamp":1761069617000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089326123000211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S1089326123000211"],"URL":"https:\/\/doi.org\/10.1016\/j.cld.2023.01.021","relation":{},"ISSN":["1089-3261"],"issn-type":[{"value":"1089-3261","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Physicians' Use of Digital Health Interventions in the Management of Nonalcoholic Fatty Liver Disease","name":"articletitle","label":"Article Title"},{"value":"Clinics in Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cld.2023.01.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}