{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:23:00Z","timestamp":1788445380525,"version":"build-2803163510"},"reference-count":83,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"am","delay-in-days":334,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000027","name":"NIAAA","doi-asserted-by":"publisher","award":["AA R01 030748"],"award-info":[{"award-number":["AA R01 030748"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"NIAAA","doi-asserted-by":"publisher","award":["AA R01 030969"],"award-info":[{"award-number":["AA R01 030969"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"NIAAA","doi-asserted-by":"publisher","award":["AA R01 030470"],"award-info":[{"award-number":["AA R01 030470"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","theclinics.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Liver Disease"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.cld.2024.06.011","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T14:37:09Z","timestamp":1727793429000},"page":"761-778","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Treatment of Alcohol Use Disorder"],"prefix":"10.1016","volume":"28","author":[{"given":"Kinza","family":"Tareen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin G.","family":"Clifton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ponni","family":"Perumalswami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L.","family":"Mellinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald Scott","family":"Winder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.cld.2024.06.011_bib1","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.cgh.2022.03.017","article-title":"Alcohol-associated liver disease mortality increased from 2017 to 2020 and accelerated during the COVID-19 pandemic","volume":"20","author":"Deutsch-Link","year":"2022","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.cld.2024.06.011_bib2","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.jhep.2022.04.040","article-title":"Ethyl glucuronide in hair detects a high rate of harmful alcohol consumption in presumed non-alcoholic fatty liver disease","volume":"77","author":"Staufer","year":"2022","journal-title":"J\u00a0Hepatol"},{"issue":"10","key":"10.1016\/j.cld.2024.06.011_bib3","doi-asserted-by":"crossref","first-page":"e0162980","DOI":"10.1371\/journal.pone.0162980","article-title":"The SCottish alcoholic liver disease evaluation: a population-level matched cohort study of hospital-based costs, 1991-2011","volume":"11","author":"Bouttell","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.cld.2024.06.011_bib4","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.14309\/ajg.0000000000000340","article-title":"Alcohol consumption and risk of liver cirrhosis: a systematic review and meta-analysis","volume":"114","author":"Roerecke","year":"2019","journal-title":"Am J Gastroenterol"},{"issue":"11","key":"10.1016\/j.cld.2024.06.011_bib5","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1016\/j.cgh.2020.10.026","article-title":"Provider attitudes and practices for alcohol screening, treatment, and education in patients with liver disease: a survey from the American association for the study of liver diseases alcohol-associated liver disease special interest group","volume":"19","author":"Im","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib6","first-page":"e119","article-title":"Simultaneous management of alcohol use disorder and liver disease: a systematic review and meta-analysis","volume":"17","author":"Elfeki","year":"2023","journal-title":"J\u00a0Addict Med"},{"issue":"10","key":"10.1016\/j.cld.2024.06.011_bib7","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1001\/jamainternmed.2017.3947","article-title":"Collaborative care for opioid and alcohol use disorders in primary care: the SUMMIT randomized clinical trial","volume":"177","author":"Watkins","year":"2017","journal-title":"JAMA Intern Med"},{"issue":"5","key":"10.1016\/j.cld.2024.06.011_bib8","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1002\/lt.26375","article-title":"Burnout among transplant hepatologists in the United States","volume":"28","author":"Pourmand","year":"2022","journal-title":"Liver Transpl"},{"issue":"7","key":"10.1016\/j.cld.2024.06.011_bib9","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1002\/lt.26462","article-title":"Interprofessional teams are crucial to reduce transplantation hepatology burnout","volume":"28","author":"Winder","year":"2022","journal-title":"Liver Transpl"},{"issue":"3","key":"10.1016\/j.cld.2024.06.011_bib10","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.psym.2019.12.004","article-title":"Confronting the crisis of comorbid alcohol use disorder and alcohol-related liver disease with a novel multidisciplinary clinic","volume":"61","author":"Winder","year":"2020","journal-title":"Psychosomatics"},{"key":"10.1016\/j.cld.2024.06.011_bib11","doi-asserted-by":"crossref","DOI":"10.1097\/HEP.0000000000000645","article-title":"New insights into the molecular basis of alcohol abstinence and relapse in alcohol-associated liver disease","author":"Diaz","year":"2023","journal-title":"Hepatology"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib12","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.cgh.2015.07.047","article-title":"Efficacy of psychosocial interventions in inducing and maintaining alcohol abstinence in patients with chronic liver disease: a systematic review","volume":"14","author":"Khan","year":"2016","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"9","key":"10.1016\/j.cld.2024.06.011_bib13","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1111\/add.12950","article-title":"Specialty substance use disorder services following brief alcohol intervention: a meta-analysis of randomized controlled trials","volume":"110","author":"Glass","year":"2015","journal-title":"Addiction"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib14","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1093\/alcalc\/agt170","article-title":"The impact of brief alcohol interventions in primary healthcare: a systematic review of reviews","volume":"49","author":"O'Donnell","year":"2014","journal-title":"Alcohol Alcohol"},{"issue":"Suppl 4","key":"10.1016\/j.cld.2024.06.011_bib15","doi-asserted-by":"crossref","first-page":"S466","DOI":"10.4103\/0019-5545.224352","article-title":"Brief intervention in substance use disorders","volume":"60","author":"Mattoo","year":"2018","journal-title":"Indian J Psychiatry"},{"issue":"10","key":"10.1016\/j.cld.2024.06.011_bib16","doi-asserted-by":"crossref","first-page":"e0204890","DOI":"10.1371\/journal.pone.0204890","article-title":"Effectiveness of Motivational Interviewing on adult behaviour change in health and social care settings: a systematic review of reviews","volume":"13","author":"Frost","year":"2018","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.cld.2024.06.011_bib17","first-page":"CD009269","article-title":"Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users","volume":"12","author":"Klimas","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib18","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1093\/alcalc\/agu098","article-title":"Can motivational interviewing in emergency care reduce alcohol consumption in young people? A systematic review and meta-analysis","volume":"50","author":"Kohler","year":"2015","journal-title":"Alcohol Alcohol"},{"issue":"4","key":"10.1016\/j.cld.2024.06.011_bib19","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.chc.2016.06.002","article-title":"Cognitive behavioral therapy and motivational enhancement therapy","volume":"25","author":"Wu","year":"2016","journal-title":"Child Adolesc Psychiatr Clin N Am"},{"issue":"4","key":"10.1016\/j.cld.2024.06.011_bib20","doi-asserted-by":"crossref","first-page":"356","DOI":"10.15288\/jsa.1990.51.356","article-title":"Failure of a 2-hour motivational intervention to alter recurrent drinking behavior in alcoholics with gastrointestinal disease","volume":"51","author":"Kuchipudi","year":"1990","journal-title":"J\u00a0Stud Alcohol"},{"issue":"6","key":"10.1016\/j.cld.2024.06.011_bib21","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1002\/hep.31058","article-title":"A\u00a0randomized controlled trial of an integrated alcohol reduction intervention in patients with hepatitis C infection","volume":"71","author":"Proeschold-Bell","year":"2020","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.cld.2024.06.011_bib22","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/lt.22259","article-title":"A\u00a0randomized, controlled study of treatment for alcohol dependence in patients awaiting liver transplantation","volume":"17","author":"Weinrieb","year":"2011","journal-title":"Liver Transpl"},{"issue":"16","key":"10.1016\/j.cld.2024.06.011_bib23","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1001\/archinte.159.16.1946","article-title":"A\u00a0randomized trial of integrated outpatient treatment for medically ill alcoholic men","volume":"159","author":"Willenbring","year":"1999","journal-title":"Arch Intern Med"},{"issue":"8","key":"10.1016\/j.cld.2024.06.011_bib24","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1037\/adb0000311","article-title":"Cognitive behavioral interventions for alcohol and drug use disorders: through the stage model and back again","volume":"31","author":"Carroll","year":"2017","journal-title":"Psychol Addict Behav"},{"issue":"5","key":"10.1016\/j.cld.2024.06.011_bib25","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1093\/alcalc\/agab016","article-title":"Cognitive-behavioral interventions targeting alcohol or other drug use and Co-occurring mental health disorders: a meta-analysis","volume":"56","author":"Mehta","year":"2021","journal-title":"Alcohol Alcohol"},{"issue":"9","key":"10.1016\/j.cld.2024.06.011_bib26","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1111\/add.12589","article-title":"Prize-based contingency management for the treatment of substance abusers: a meta-analysis","volume":"109","author":"Benishek","year":"2014","journal-title":"Addiction"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib27","doi-asserted-by":"crossref","first-page":"89","DOI":"10.15288\/jsad.22-00036","article-title":"Contingency management in Canadian addiction treatment: provider attitudes and use","volume":"84","author":"Cowie","year":"2023","journal-title":"J\u00a0Stud Alcohol Drugs"},{"issue":"22","key":"10.1016\/j.cld.2024.06.011_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/DQKL6124","article-title":"Adjunctive Medication Management and Contingency Management to enhance adherence to acamprosate for alcohol dependence: the ADAM trial RCT","volume":"27","author":"Donoghue","year":"2023","journal-title":"Health Technol Assess"},{"issue":"10","key":"10.1016\/j.cld.2024.06.011_bib29","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/jamapsychiatry.2021.1969","article-title":"Contingency management for patients receiving medication for opioid use disorder: a systematic review and meta-analysis","volume":"78","author":"Bolivar","year":"2021","journal-title":"JAMA Psychiatr"},{"key":"10.1016\/j.cld.2024.06.011_bib30","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jsat.2016.09.008","article-title":"Contingency management: new directions and remaining challenges for an evidence-based intervention","volume":"72","author":"Rash","year":"2017","journal-title":"J\u00a0Subst Abuse Treat"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib31","doi-asserted-by":"crossref","first-page":"06","DOI":"10.35946\/arcr.v41.1.06","article-title":"The role of the family in alcohol use disorder recovery for adults","volume":"41","author":"McCrady","year":"2021","journal-title":"Alcohol Res"},{"key":"10.1016\/j.cld.2024.06.011_bib32","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.drugalcdep.2016.06.010","article-title":"Network Support II: randomized controlled trial of Network Support treatment and cognitive behavioral therapy for alcohol use disorder","volume":"165","author":"Litt","year":"2016","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.cld.2024.06.011_bib33","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.cct.2016.08.006","article-title":"An exploratory evaluation of Take Control: a novel computer-delivered behavioral platform for placebo-controlled pharmacotherapy trials for alcohol use disorder","volume":"50","author":"Devine","year":"2016","journal-title":"Contemp Clin Trials"},{"key":"10.1016\/j.cld.2024.06.011_bib34","doi-asserted-by":"crossref","first-page":"e47404","DOI":"10.2196\/47404","article-title":"Testing a digital health app for patients with alcohol-associated liver disease: mixed methods usability study","volume":"7","author":"Park","year":"2023","journal-title":"JMIR Form Res"},{"issue":"4","key":"10.1016\/j.cld.2024.06.011_bib35","doi-asserted-by":"crossref","first-page":"e0093","DOI":"10.1097\/HC9.0000000000000093","article-title":"Medications for alcohol use disorder improve survival in patients with hazardous drinking and alcohol-associated cirrhosis","volume":"7","author":"Rabiee","year":"2023","journal-title":"Hepatol Commun"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib36","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/acer.13944","article-title":"Gender disparities in alcohol use disorder treatment among privately insured patients with alcohol-associated cirrhosis","volume":"43","author":"Mellinger","year":"2019","journal-title":"Alcohol Clin Exp Res"},{"issue":"5","key":"10.1016\/j.cld.2024.06.011_bib37","first-page":"741","article-title":"Naltrexone long-acting formulation in the treatment of alcohol dependence","volume":"3","author":"Johnson","year":"2007","journal-title":"Therapeut Clin Risk Manag"},{"issue":"3","key":"10.1016\/j.cld.2024.06.011_bib38","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0168-8278(97)80355-8","article-title":"Effect of liver cirrhosis on the systemic availability of naltrexone in humans","volume":"27","author":"Bertolotti","year":"1997","journal-title":"J\u00a0Hepatol"},{"issue":"12","key":"10.1016\/j.cld.2024.06.011_bib39","doi-asserted-by":"crossref","first-page":"3433","DOI":"10.1002\/hep4.2080","article-title":"Naltrexone for alcohol use disorder: hepatic safety in patients with and without liver disease","volume":"6","author":"Ayyala","year":"2022","journal-title":"Hepatology Communications"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib40","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/hep.30145","article-title":"Primary biliary cholangitis: 2018 practice guidance from the American association for the study of liver diseases","volume":"69","author":"Lindor","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2024.06.011_bib41","first-page":"CD004332","article-title":"Acamprosate for alcohol dependence","volume":"9","author":"Rosner","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib42","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2174\/187152710790966641","article-title":"Acamprosate: a prototypic neuromodulator in the treatment of alcohol dependence","volume":"9","author":"Mason","year":"2010","journal-title":"CNS Neurol Disord: Drug Targets"},{"key":"10.1016\/j.cld.2024.06.011_bib43","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2147\/TCRM.S23184","article-title":"Acamprosate for treatment of alcohol dependence: mechanisms, efficacy, and clinical utility","volume":"8","author":"Witkiewitz","year":"2012","journal-title":"Ther Clin Risk Manag"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib44","first-page":"158","article-title":"The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder","volume":"17","author":"Reus","year":"2019","journal-title":"Focus (Am Psychiatr Publ)"},{"issue":"3","key":"10.1016\/j.cld.2024.06.011_bib45","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.ccc.2017.03.012","article-title":"Novel algorithms for the prophylaxis and management of alcohol withdrawal syndromes-beyond benzodiazepines","volume":"33","author":"Maldonado","year":"2017","journal-title":"Crit Care Clin"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib46","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/13543784.2018.1417383","article-title":"Gabapentin for the treatment of alcohol use disorder","volume":"27","author":"Mason","year":"2018","journal-title":"Expert Opin Investig Drugs"},{"issue":"11","key":"10.1016\/j.cld.2024.06.011_bib47","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.4088\/JCP.v68n1108","article-title":"Gabapentin reduces alcohol consumption and craving: a randomized, double-blind, placebo-controlled trial","volume":"68","author":"Furieri","year":"2007","journal-title":"J\u00a0Clin Psychiatry"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib48","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/s41575-021-00527-0","article-title":"Management of alcohol use disorder in patients with cirrhosis in the setting of liver transplantation","volume":"19","author":"Arab","year":"2022","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"5","key":"10.1016\/j.cld.2024.06.011_bib49","doi-asserted-by":"crossref","first-page":"720","DOI":"10.7326\/M21-4011","article-title":"The management of substance use disorders: synopsis of the 2021\u00a0U.S. Department of veterans Affairs and U.S. Department of defense clinical practice guideline","volume":"175","author":"Perry","year":"2022","journal-title":"Ann Intern Med"},{"issue":"8","key":"10.1016\/j.cld.2024.06.011_bib50","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1001\/jama.2018.11406","article-title":"Diagnosis and pharmacotherapy of alcohol use disorder: a review","volume":"320","author":"Kranzler","year":"2018","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.cld.2024.06.011_bib51","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s40265-021-01670-3","article-title":"Novel agents for the pharmacological treatment of alcohol use disorder","volume":"82","author":"Burnette","year":"2022","journal-title":"Drugs"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib52","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/JCP.0000000000000246","article-title":"Zonisamide, topiramate, and levetiracetam: efficacy and neuropsychological effects in alcohol use disorders","volume":"35","author":"Knapp","year":"2015","journal-title":"J\u00a0Clin Psychopharmacol"},{"issue":"8","key":"10.1016\/j.cld.2024.06.011_bib53","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1111\/add.14191","article-title":"Baclofen: its effectiveness in reducing harmful drinking, craving, and negative mood. A meta-analysis","volume":"113","author":"Rose","year":"2018","journal-title":"Addiction"},{"issue":"9603","key":"10.1016\/j.cld.2024.06.011_bib54","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1016\/S0140-6736(07)61814-5","article-title":"Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study","volume":"370","author":"Addolorato","year":"2007","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.cld.2024.06.011_bib55","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1111\/add.13787","article-title":"The safety and efficacy of baclofen to reduce alcohol use in veterans with chronic hepatitis C: a randomized controlled trial","volume":"112","author":"Hauser","year":"2017","journal-title":"Addiction"},{"issue":"6","key":"10.1016\/j.cld.2024.06.011_bib56","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1192\/bjp.2018.13","article-title":"Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial","volume":"212","author":"Morley","year":"2018","journal-title":"Br J Psychiatry"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib57","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/s41380-018-0287-y","article-title":"A\u00a0deeper insight into how GABA-B receptor agonism via baclofen may affect alcohol seeking and consumption: lessons learned from a human laboratory investigation","volume":"26","author":"Farokhnia","year":"2021","journal-title":"Mol Psychiatry"},{"issue":"5","key":"10.1016\/j.cld.2024.06.011_bib58","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/jcph.247","article-title":"Pharmacokinetic characterization of baclofen in patients with chronic kidney disease: dose adjustment recommendations","volume":"54","author":"Vlavonou","year":"2014","journal-title":"J\u00a0Clin Pharmacol"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib59","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1053\/j.ajkd.2018.01.057","article-title":"Helping patients with ESRD and earlier stages of CKD to quit smoking","volume":"72","author":"Formanek","year":"2018","journal-title":"Am J Kidney Dis"},{"issue":"10037","key":"10.1016\/j.cld.2024.06.011_bib60","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1016\/S0140-6736(16)30272-0","article-title":"Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial","volume":"387","author":"Anthenelli","year":"2016","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.cld.2024.06.011_bib61","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1080\/13543784.2018.1501471","article-title":"N-acetyl cysteine in the treatment of alcohol use disorder in patients with liver disease: rationale for further research","volume":"27","author":"Morley","year":"2018","journal-title":"Expert Opin Investig Drugs"},{"issue":"7","key":"10.1016\/j.cld.2024.06.011_bib62","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1097\/01.ALC.0000075547.77464.76","article-title":"Effects of ondansetron in early- versus late-onset\u00a0alcoholics: a prospective, open-label study","volume":"27","author":"Kranzler","year":"2003","journal-title":"Alcohol Clin Exp Res"},{"issue":"3","key":"10.1016\/j.cld.2024.06.011_bib63","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/j.1552-4604.1996.tb04190.x","article-title":"Pharmacokinetics of ondansetron in patients with hepatic insufficiency","volume":"36","author":"Figg","year":"1996","journal-title":"J\u00a0Clin Pharmacol"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib64","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.3390\/ijms24021703","article-title":"GLP-1 receptor agonists in non-alcoholic fatty liver disease: current evidence and future perspectives","volume":"24","author":"Nevola","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"12","key":"10.1016\/j.cld.2024.06.011_bib65","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/S2215-0366(19)30222-6","article-title":"Psychiatric comorbidities in alcohol use disorder","volume":"6","author":"Castillo-Carniglia","year":"2019","journal-title":"Lancet Psychiatr"},{"issue":"Suppl 2","key":"10.1016\/j.cld.2024.06.011_bib66","doi-asserted-by":"crossref","first-page":"S379","DOI":"10.4103\/indianjpsychiatry.indianjpsychiatry_18_22","article-title":"Management of psychiatric disorders in patients with hepatic and gastrointestinal diseases","volume":"64","author":"Menon","year":"2022","journal-title":"Indian J Psychiatry"},{"issue":"12","key":"10.1016\/j.cld.2024.06.011_bib67","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.4088\/JCP.09r05786blu","article-title":"Serotonin reuptake inhibitor antidepressants and abnormal bleeding: a review for clinicians and a reconsideration of mechanisms","volume":"71","author":"Andrade","year":"2010","journal-title":"J\u00a0Clin Psychiatry"},{"issue":"3","key":"10.1016\/j.cld.2024.06.011_bib68","doi-asserted-by":"crossref","first-page":"269","DOI":"10.4306\/pi.2011.8.3.269","article-title":"Duloxetine-induced liver injury in patients with major depressive disorder","volume":"8","author":"Kang","year":"2011","journal-title":"Psychiatry Investig"},{"issue":"10","key":"10.1016\/j.cld.2024.06.011_bib69","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1111\/liv.14973","article-title":"Impact of major depression and antidepressant use on alcoholic and non-alcoholic fatty liver disease: a population-based study","volume":"41","author":"Shaheen","year":"2021","journal-title":"Liver Int"},{"issue":"4","key":"10.1016\/j.cld.2024.06.011_bib70","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.drudis.2016.02.015","article-title":"DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans","volume":"21","author":"Chen","year":"2016","journal-title":"Drug Discov Today"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib71","doi-asserted-by":"crossref","first-page":"13","DOI":"10.14302\/issn.2641-7669.ject-17-1789","article-title":"The 5-ht1a agonist buspirone decreases liver oxidative stress and exerts protective effect against CCl4\u2013 toxicity","volume":"1","author":"Abdel-Salam NMS","year":"2017","journal-title":"Journal of Experimental and Clinical Toxicology"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib72","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jaclp.2022.09.006","article-title":"Antipsychotic safety in liver disease: a narrative review and practical guide for the clinician","volume":"64","author":"Gunther","year":"2023","journal-title":"J\u00a0Acad Consult Liaison Psychiatry"},{"issue":"2","key":"10.1016\/j.cld.2024.06.011_bib73","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1097\/WNF.0b013e3181cda242","article-title":"Treatment effects of gabapentin for primary insomnia","volume":"33","author":"Lo","year":"2010","journal-title":"Clin Neuropharmacol"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib74","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s11414-016-9538-3","article-title":"Reasons for not seeking substance use disorder treatment: variations by health insurance coverage","volume":"44","author":"Ali","year":"2017","journal-title":"J\u00a0Behav Health Serv Res"},{"key":"10.1016\/j.cld.2024.06.011_bib75","series-title":"The ASAM principles of addiction medicine 5th","first-page":"428","article-title":"The ASAM criteria and matching patients to treatment","author":"Mee-Lee","year":"2015"},{"issue":"1","key":"10.1016\/j.cld.2024.06.011_bib76","doi-asserted-by":"crossref","first-page":"13","DOI":"10.35946\/arcr.v42.1.13","article-title":"Alcohol use disorder and alcohol-associated liver disease","volume":"42","author":"Ramkissoon","year":"2022","journal-title":"Alcohol Res"},{"issue":"12","key":"10.1016\/j.cld.2024.06.011_bib77","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S2215-0366(19)30213-5","article-title":"Prevention, screening, and treatment for heavy drinking and alcohol use disorder","volume":"6","author":"Knox","year":"2019","journal-title":"Lancet Psychiatr"},{"issue":"7","key":"10.1016\/j.cld.2024.06.011_bib78","doi-asserted-by":"crossref","first-page":"e00145","DOI":"10.1097\/HC9.0000000000000145","article-title":"Management of alcohol use disorder in patients with chronic liver disease","volume":"7","author":"Mellinger","year":"2023","journal-title":"Hepatol Commun"},{"issue":"5","key":"10.1016\/j.cld.2024.06.011_bib79","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S2468-1253(19)30415-7","article-title":"Outpatient management of alcohol-related liver disease","volume":"5","author":"Simonetto","year":"2020","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"3","key":"10.1016\/j.cld.2024.06.011_bib80","first-page":"CD012880","article-title":"Alcoholics Anonymous and other 12-step programs for alcohol use disorder","volume":"3","author":"Kelly","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.cld.2024.06.011_bib81","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jsat.2016.10.004","article-title":"Comparison of 12-step groups to mutual help alternatives for AUD in a large, national study: differences in membership characteristics and group participation, cohesion, and satisfaction","volume":"73","author":"Zemore","year":"2017","journal-title":"J\u00a0Subst Abuse Treat"},{"issue":"7","key":"10.1016\/j.cld.2024.06.011_bib82","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1111\/j.1360-0443.2007.01846.x","article-title":"An examination of main and interactive effects of substance abuse recovery housing on multiple indicators of adjustment","volume":"102","author":"Jason","year":"2007","journal-title":"Addiction"},{"issue":"6","key":"10.1016\/j.cld.2024.06.011_bib83","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.jceh.2022.03.003","article-title":"Management of alcohol withdrawal syndrome in patients with alcoholic liver disease","volume":"12","author":"Chand","year":"2022","journal-title":"J\u00a0Clin Exp Hepatol"}],"container-title":["Clinics in Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108932612400059X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108932612400059X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T12:36:05Z","timestamp":1729600565000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S108932612400059X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":83,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S108932612400059X"],"URL":"https:\/\/doi.org\/10.1016\/j.cld.2024.06.011","relation":{},"ISSN":["1089-3261"],"issn-type":[{"value":"1089-3261","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatment of Alcohol Use Disorder","name":"articletitle","label":"Article Title"},{"value":"Clinics in Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cld.2024.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}